Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer

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Articles by Olson, E. N.

				K. Nagao, Y. Taniyama, T. Kietzmann, T. Doi, I. Komuro, and R. Morishita HIF-1{alpha} Signaling Upstream of NKX2.5 Is Required for Cardiac Development in Xenopus J. Biol. Chem., April 25, 2008; 283(17): 11841 - 11849. [Abstract] [Full Text] [PDF]

				P. F. van Loo, E. A. F. Mahtab, L. J. Wisse, J. Hou, F. Grosveld, G. Suske, S. Philipsen, and A. C. Gittenberger-de Groot Transcription Factor Sp3 Knockout Mice Display Serious Cardiac Malformations Mol. Cell. Biol., December 15, 2007; 27(24): 8571 - 8582. [Abstract] [Full Text] [PDF]

				Y. Zhang, N. Rath, S. Hannenhalli, Z. Wang, T. Cappola, S. Kimura, E. Atochina-Vasserman, M. M. Lu, M. F. Beers, and E. E. Morrisey GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo Development, January 1, 2007; 134(1): 189 - 198. [Abstract] [Full Text] [PDF]

				E. E. Creemers, L. B. Sutherland, J. McAnally, J. A. Richardson, and E. N. Olson Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development Development, November 1, 2006; 133(21): 4245 - 4256. [Abstract] [Full Text] [PDF]

				C. Karamboulas, G. D. Dakubo, J. Liu, Y. De Repentigny, K. Yutzey, V. A. Wallace, R. Kothary, and I. S. Skerjanc Disruption of MEF2 activity in cardiomyoblasts inhibits cardiomyogenesis J. Cell Sci., October 15, 2006; 119(20): 4315 - 4321. [Abstract] [Full Text] [PDF]

				M. Xin, C. A. Davis, J. D. Molkentin, C.-L. Lien, S. A. Duncan, J. A. Richardson, and E. N. Olson A threshold of GATA4 and GATA6 expression is required for cardiovascular development PNAS, July 25, 2006; 103(30): 11189 - 11194. [Abstract] [Full Text] [PDF]

				X. Chi, P. K. Chatterjee, W. Wilson III, S.-X. Zhang, F. J. DeMayo, and R. J. Schwartz Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modules PNAS, September 20, 2005; 102(38): 13490 - 13495. [Abstract] [Full Text] [PDF]

				A. Rojas, S. De Val, A. B. Heidt, S.-M. Xu, J. Bristow, and B. L. Black Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element Development, August 1, 2005; 132(15): 3405 - 3417. [Abstract] [Full Text] [PDF]

				D. Phan, T. L. Rasmussen, O. Nakagawa, J. McAnally, P. D. Gottlieb, P. W. Tucker, J. A. Richardson, R. Bassel-Duby, and E. N. Olson BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart Development, June 1, 2005; 132(11): 2669 - 2678. [Abstract] [Full Text] [PDF]

				J. K. Takeuchi, M. Mileikovskaia, K. Koshiba-Takeuchi, A. B. Heidt, A. D. Mori, E. P. Arruda, M. Gertsenstein, R. Georges, L. Davidson, R. Mo, et al. Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development Development, May 15, 2005; 132(10): 2463 - 2474. [Abstract] [Full Text] [PDF]

				D. G. McFadden, A. C. Barbosa, J. A. Richardson, M. D. Schneider, D. Srivastava, and E. N. Olson The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner Development, January 1, 2005; 132(1): 189 - 201. [Abstract] [Full Text] [PDF]

				I. S. Kathiriya, I. N. King, M. Murakami, M. Nakagawa, J. M. Astle, K. A. Gardner, R. D. Gerard, E. N. Olson, D. Srivastava, and O. Nakagawa Hairy-related Transcription Factors Inhibit GATA-dependent Cardiac Gene Expression through a Signal-responsive Mechanism J. Biol. Chem., December 24, 2004; 279(52): 54937 - 54943. [Abstract] [Full Text] [PDF]

				J. Oh, Z. Wang, D.-Z. Wang, C.-L. Lien, W. Xing, and E. N. Olson Target Gene-Specific Modulation of Myocardin Activity by GATA Transcription Factors Mol. Cell. Biol., October 1, 2004; 24(19): 8519 - 8528. [Abstract] [Full Text] [PDF]

				K.-H. Lee, S. Evans, T. Y. Ruan, and A. B. Lassar SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer Development, October 1, 2004; 131(19): 4709 - 4723. [Abstract] [Full Text] [PDF]

				E. Dodou, M. P. Verzi, J. P. Anderson, S.-M. Xu, and B. L. Black Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development Development, August 15, 2004; 131(16): 3931 - 3942. [Abstract] [Full Text] [PDF]

				S. Pikkarainen, H. Tokola, R. Kerkela, and H. Ruskoaho GATA transcription factors in the developing and adult heart Cardiovasc Res, August 1, 2004; 63(2): 196 - 207. [Abstract] [Full Text] [PDF]

				C. O. Brown III, X. Chi, E. Garcia-Gras, M. Shirai, X.-H. Feng, and R. J. Schwartz The Cardiac Determination Factor, Nkx2-5, Is Activated by Mutual Cofactors GATA-4 and Smad1/4 via a Novel Upstream Enhancer J. Biol. Chem., March 12, 2004; 279(11): 10659 - 10669. [Abstract] [Full Text] [PDF]

				E. N. Olson and M. D. Schneider Sizing up the heart: development redux in disease Genes & Dev., August 15, 2003; 17(16): 1937 - 1956. [Full Text] [PDF]

				P. E.M.H. Habets, A. F.M. Moorman, and V. M. Christoffels Regulatory modules in the developing heart Cardiovasc Res, May 1, 2003; 58(2): 246 - 263. [Abstract] [Full Text] [PDF]

				M. J. Solloway and R. P. Harvey Molecular pathways in myocardial development: a stem cell perspective Cardiovasc Res, May 1, 2003; 58(2): 264 - 277. [Abstract] [Full Text] [PDF]

				I. I. Rybkin, D. W. Markham, Z. Yan, R. Bassel-Duby, R. S. Williams, and E. N. Olson Conditional Expression of SV40 T-antigen in Mouse Cardiomyocytes Facilitates an Inducible Switch from Proliferation to Differentiation J. Biol. Chem., April 25, 2003; 278(18): 15927 - 15934. [Abstract] [Full Text] [PDF]

				M. L. Clabby, T. A. Robison, H. F. Quigley, D. B. Wilson, and D. P. Kelly Retinoid X Receptor alpha Represses GATA-4-mediated Transcription via a Retinoid-dependent Interaction with the Cardiac-enriched Repressor FOG-2 J. Biol. Chem., February 14, 2003; 278(8): 5760 - 5767. [Abstract] [Full Text] [PDF]

				S. Zaffran and M. Frasch Early Signals in Cardiac Development Circ. Res., September 20, 2002; 91(6): 457 - 469. [Abstract] [Full Text] [PDF]

				N. Bodyak, P. M. Kang, M. Hiromura, I. Sulijoadikusumo, N. Horikoshi, K. Khrapko, and A. Usheva Gene expression profiling of the aging mouse cardiac myocytes Nucleic Acids Res., September 1, 2002; 30(17): 3788 - 3794. [Abstract] [Full Text] [PDF]

				Y.-S. Dai, P. Cserjesi, B. E. Markham, and J. D. Molkentin The Transcription Factors GATA4 and dHAND Physically Interact to Synergistically Activate Cardiac Gene Expression through a p300-dependent Mechanism J. Biol. Chem., June 28, 2002; 277(27): 24390 - 24398. [Abstract] [Full Text] [PDF]

				D.-Z. Wang, M. R. Valdez, J. McAnally, J. Richardson, and E. N. Olson The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development Development, November 15, 2001; 128(22): 4623 - 4633. [Abstract] [Full Text] [PDF]

				M. Jamali, P. J. Rogerson, S. Wilton, and I. S. Skerjanc Nkx2-5 Activity Is Essential for Cardiomyogenesis J. Biol. Chem., November 2, 2001; 276(45): 42252 - 42258. [Abstract] [Full Text] [PDF]

				Y. Kong, J. M. Shelton, B. Rothermel, X. Li, J. A. Richardson, R. Bassel-Duby, and R. S. Williams Cardiac-Specific LIM Protein FHL2 Modifies the Hypertrophic Response to {beta}-Adrenergic Stimulation Circulation, June 5, 2001; 103(22): 2731 - 2738. [Abstract] [Full Text] [PDF]

				S. Bekri, G. Kispal, H. Lange, E. Fitzsimons, J. Tolmie, R. Lill, and D. F. Bishop Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation Blood, November 1, 2000; 96(9): 3256 - 3264. [Abstract] [Full Text] [PDF]

				D. McFadden, J Charite, J. Richardson, D Srivastava, A. Firulli, and E. Olson A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart Development, January 12, 2000; 127(24): 5331 - 5341. [Abstract] [PDF]