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Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities
Development, February 15, 2009; 136(4): 585 - 594.
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H. L. Holen, M. Shadidi, K. Narvhus, O. Kjosnes, A. Tierens, and H.-C. Aasheim
Signaling through ephrin-A ligand leads to activation of Src-family kinases, Akt phosphorylation, and inhibition of antigen receptor-induced apoptosis
J. Leukoc. Biol., October 1, 2008; 84(4): 1183 - 1191.
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Arch Otolaryngol Head Neck SurgHome page
E. J. Yavrouian, U. K. Sinha, D. H. Rice, M. T. Salam, P. S. Gill, and R. Masood
The Significance of EphB4 and EphrinB2 Expression and Survival in Head and Neck Squamous Cell Carcinoma
Arch Otolaryngol Head Neck Surg, September 1, 2008; 134(9): 985 - 991.
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T. Yamashita, K. Ohneda, M. Nagano, C. Miyoshi, N. Kaneko, Y. Miwa, M. Yamamoto, O. Ohneda, and Y. Fujii-Kuriyama
Hypoxia-inducible Transcription Factor-2{alpha} in Endothelial Cells Regulates Tumor Neovascularization through Activation of Ephrin A1
J. Biol. Chem., July 4, 2008; 283(27): 18926 - 18936.
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R Holm, S Knopp, Z Suo, C Trope, and J M Nesland
Expression of EphA2 and EphrinA-1 in vulvar carcinomas and its relation to prognosis
J. Clin. Pathol., October 1, 2007; 60(10): 1086 - 1091.
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E. C. Bolton, A. Y. So, C. Chaivorapol, C. M. Haqq, H. Li, and K. R. Yamamoto
Cell- and gene-specific regulation of primary target genes by the androgen receptor
Genes & Dev., August 15, 2007; 21(16): 2005 - 2017.
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S. Alam, J Fujimoto, I Jahan, E Sato, and T Tamaya
Overexpression of ephrinB2 and EphB4 in tumor advancement of uterine endometrial cancers
Ann. Onc., March 1, 2007; 18(3): 485 - 490.
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F. Liu, P. J. Park, W. Lai, E. Maher, A. Chakravarti, L. Durso, X. Jiang, Y. Yu, A. Brosius, M. Thomas, et al.
A Genome-Wide Screen Reveals Functional Gene Clusters in the Cancer Genome and Identifies EphA2 as a Mitogen in Glioblastoma
Cancer Res., November 15, 2006; 66(22): 10815 - 10823.
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U. K. Sinha, K. Mazhar, S. B. Chinn, V. K. Dhillon, L. Liu, R. Masood, D. H. Rice, and P. S. Gill
The Association Between Elevated EphB4 Expression, Smoking Status, and Advanced-Stage Disease in Patients With Head and Neck Squamous Cell Carcinoma.
Arch Otolaryngol Head Neck Surg, October 1, 2006; 132(10): 1053 - 1059.
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H. Guo, H. Miao, L. Gerber, J. Singh, M. F. Denning, A. C. Gilliam, and B. Wang
Disruption of EphA2 Receptor Tyrosine Kinase Leads to Increased Susceptibility to Carcinogenesis in Mouse Skin.
Cancer Res., July 15, 2006; 66(14): 7050 - 7058.
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S. R. Kumar, J. Singh, G. Xia, V. Krasnoperov, L. Hassanieh, E. J. Ley, J. Scehnet, N. G. Kumar, D. Hawes, M. F. Press, et al.
Receptor Tyrosine Kinase EphB4 Is a Survival Factor in Breast Cancer
Am. J. Pathol., July 1, 2006; 169(1): 279 - 293.
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M. Takano-Maruyama, K. Hase, H. Fukamachi, Y. Kato, H. Koseki, and H. Ohno
Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine
Am J Physiol Gastrointest Liver Physiol, July 1, 2006; 291(1): G163 - G170.
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S. Abraham, D. W. Knapp, L. Cheng, P. W. Snyder, S. K. Mittal, D. S. Bangari, M. Kinch, L. Wu, J. Dhariwal, and S. I. Mohammed
Expression of EphA2 and Ephrin A-1 in Carcinoma of the Urinary Bladder
Clin. Cancer Res., January 15, 2006; 12(2): 353 - 360.
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M. Parri, F. Buricchi, M. L. Taddei, E. Giannoni, G. Raugei, G. Ramponi, and P. Chiarugi
EphrinA1 Repulsive Response Is Regulated by an EphA2 Tyrosine Phosphatase
J. Biol. Chem., October 7, 2005; 280(40): 34008 - 34018.
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H. Matsuoka, H. Obama, M. L. Kelly, T. Matsui, and M. Nakamoto
Biphasic Functions of the Kinase-defective Ephb6 Receptor in Cell Adhesion and Migration
J. Biol. Chem., August 12, 2005; 280(32): 29355 - 29363.
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G. Xia, S. R. Kumar, R. Masood, M. Koss, C. Templeman, D. Quinn, S. Zhu, R. Reddy, V. Krasnoperov, and P. S. Gill
Up-Regulation of EphB4 in Mesothelioma and Its Biological Significance
Clin. Cancer Res., June 15, 2005; 11(12): 4305 - 4315.
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G. Xia, S. R. Kumar, R. Masood, S. Zhu, R. Reddy, V. Krasnoperov, D. I. Quinn, S. M. Henshall, R. L. Sutherland, J. K. Pinski, et al.
EphB4 Expression and Biological Significance in Prostate Cancer
Cancer Res., June 1, 2005; 65(11): 4623 - 4632.
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X. Ran and J. Song
Structural Insight into the Binding Diversity between the Tyr-phosphorylated Human EphrinBs and Nck2 SH2 Domain
J. Biol. Chem., May 13, 2005; 280(19): 19205 - 19212.
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BloodHome page
H.-C. Aasheim, J. Delabie, and E. F. Finne
Ephrin-A1 binding to CD4+ T lymphocytes stimulates migration and induces tyrosine phosphorylation of PYK2
Blood, April 1, 2005; 105(7): 2869 - 2876.
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S. R. F. Twigg, R. Kan, C. Babbs, E. G. Bochukova, S. P. Robertson, S. A. Wall, G. M. Morriss-Kay, and A. O. M. Wilkie
Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome
PNAS, June 8, 2004; 101(23): 8652 - 8657.
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Arterioscler. Thromb. Vasc. Bio.Home page
B. R. Shepherd, H. Y.S. Chen, C. M. Smith, G. Gruionu, S. K. Williams, and J. B. Hoying
Rapid Perfusion and Network Remodeling in a Microvascular Construct After Implantation
Arterioscler Thromb Vasc Biol, May 1, 2004; 24(5): 898 - 904.
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DevelopmentHome page
B. Fuss, F. Josten, M. Feix, and M. Hoch
Cell movements controlled by the Notch signalling cascade during foregut development in Drosophila
Development, April 1, 2004; 131(7): 1587 - 1595.
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JCBHome page
S. H. Wimmer-Kleikamp, P. W. Janes, A. Squire, P. I.H. Bastiaens, and M. Lackmann
Recruitment of Eph receptors into signaling clusters does not require ephrin contact
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W. Mao, E. Luis, S. Ross, J. Silva, C. Tan, C. Crowley, C. Chui, G. Franz, P. Senter, H. Koeppen, et al.
EphB2 as a Therapeutic Antibody Drug Target for the Treatment of Colorectal Cancer
Cancer Res., February 1, 2004; 64(3): 781 - 788.
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J. G. Wohlfahrt, C. Karagiannidis, S. Kunzmann, M. M. Epstein, W. Kempf, K. Blaser, and C. B. Schmidt-Weber
Ephrin-A1 Suppresses Th2 Cell Activation and Provides a Regulatory Link to Lung Epithelial Cells
J. Immunol., January 15, 2004; 172(2): 843 - 850.
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M. Kaneko and A. Nighorn
Interaxonal Eph-Ephrin Signaling May Mediate Sorting of Olfactory Sensory Axons in Manduca sexta
J. Neurosci., December 17, 2003; 23(37): 11523 - 11538.
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P. M. S. Alves, O. Faure, S. Graff-Dubois, D.-A. Gross, S. Cornet, S. Chouaib, I. Miconnet, F. A. Lemonnier, and K. Kosmatopoulos
EphA2 as Target of Anticancer Immunotherapy: Identification of HLA-A*0201-Restricted Epitopes
Cancer Res., December 1, 2003; 63(23): 8476 - 8480.
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A. P. SOMLYO and A. V. SOMLYO
Ca2+ Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
Physiol Rev, October 1, 2003; 83(4): 1325 - 1358.
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H. Miao, C. H. Nickel, L. G. Cantley, L. A. Bruggeman, L. N. Bennardo, and B. Wang
EphA kinase activation regulates HGF-induced epithelial branching morphogenesis
J. Cell Biol., September 29, 2003; 162(7): 1281 - 1292.
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M. Egawa, S. Yoshioka, T. Higuchi, Y. Sato, K. Tatsumi, H. Fujiwara, and S. Fujii
Ephrin B1 Is Expressed on Human Luteinizing Granulosa Cells in Corpora Lutea of the Early Luteal Phase: The Possible Involvement of the B Class Eph-Ephrin System during Corpus Luteum Formation
J. Clin. Endocrinol. Metab., September 1, 2003; 88(9): 4384 - 4392.
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J. Song
Tyrosine Phosphorylation of the Well Packed EphrinB Cytoplasmic {beta}-Hairpin for Reverse Signaling: STRUCTURAL CONSEQUENCES AND BINDING PROPERTIES
J. Biol. Chem., June 27, 2003; 278(27): 24714 - 24720.
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DevelopmentHome page
D. W. Houston and C. Wylie
The Xenopus LIM-homeodomain protein Xlim5 regulates the differential adhesion properties of early ectoderm cells
Development, June 15, 2003; 130(12): 2695 - 2704.
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A. Palmer and R. Klein
Multiple roles of ephrins in morphogenesis, neuronal networking, and brain function
Genes & Dev., June 15, 2003; 17(12): 1429 - 1450.
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C. Deroanne, V. Vouret-Craviari, B. Wang, and J. Pouyssegur
EphrinA1 inactivates integrin-mediated vascular smooth muscle cell spreading via the Rac/PAK pathway
J. Cell Sci., April 1, 2003; 116(7): 1367 - 1376.
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A. Sakakibara, Y. Ohba, K. Kurokawa, M. Matsuda, and S. Hattori
Novel function of Chat in controlling cell adhesion via Cas-Crk-C3G-pathway-mediated Rap1 activation
J. Cell Sci., March 14, 2003; 115(24): 4915 - 4924.
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DevelopmentHome page
T. Bossing and A. H. Brand
Dephrin, a transmembrane ephrin with a unique structure, prevents interneuronal axons from exiting the Drosophila embryonic CNS
Development, March 11, 2003; 129(18): 4205 - 4218.
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DevelopmentHome page
J. Ghislain, C. Desmarquet-Trin-Dinh, P. Gilardi-Hebenstreit, P. Charnay, and M. Frain
Neural crest patterning: autoregulatory and crest-specific elements co-operate for Krox20 transcriptional control
Development, March 1, 2003; 130(5): 941 - 953.
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A. Sakakibara, S. Hattori, S. Nakamura, and T. Katagiri
A Novel Hematopoietic Adaptor Protein, Chat-H, Positively Regulates T Cell Receptor-mediated Interleukin-2 Production by Jurkat Cells
J. Biol. Chem., February 14, 2003; 278(8): 6012 - 6017.
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G. Berclaz, E. Karamitopoulou, L. Mazzucchelli, V. Rohrbach, E. Dreher, A. Ziemiecki, and A.-C. Andres
Activation of the receptor protein tyrosine kinase EphB4 in endometrial hyperplasia and endometrial carcinoma
Ann. Onc., February 1, 2003; 14(2): 220 - 226.
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K. Hamada, Y. Oike, Y. Ito, H. Maekawa, K. Miyata, T. Shimomura, and T. Suda
Distinct Roles of Ephrin-B2 Forward and EphB4 Reverse Signaling in Endothelial Cells
Arterioscler Thromb Vasc Biol, February 1, 2003; 23(2): 190 - 197.
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H. Fujiwara, S. Yoshioka, K. Tatsumi, K. Kosaka, Y. Satoh, Y. Nishioka, M. Egawa, T. Higuchi, and S. Fujii
Human Endometrial Epithelial Cells Express Ephrin A1: Possible Interaction between Human Blastocysts and Endometrium via Eph-Ephrin System
J. Clin. Endocrinol. Metab., December 1, 2002; 87(12): 5801 - 5807.
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K.-I. Nagashima, A. Endo, H. Ogita, A. Kawana, A. Yamagishi, A. Kitabatake, M. Matsuda, and N. Mochizuki
Adaptor Protein Crk Is Required for Ephrin-B1-induced Membrane Ruffling and Focal Complex Assembly of Human Aortic Endothelial Cells
Mol. Biol. Cell, December 1, 2002; 13(12): 4231 - 4242.
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Mol Cancer ResHome page
N. Cheng, D. M. Brantley, H. Liu, Q. Lin, M. Enriquez, N. Gale, G. Yancopoulos, D. P. Cerretti, T. O. Daniel, and J. Chen
Blockade of EphA Receptor Tyrosine Kinase Activation Inhibits Vascular Endothelial Cell Growth Factor-Induced Angiogenesis
Mol. Cancer Res., November 1, 2002; 1(1): 2 - 11.
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X. Qu, H. Wei, Y. Zhai, H. Que, Q. Chen, F. Tang, Y. Wu, G. Xing, Y. Zhu, S. Liu, et al.
Identification, Characterization, and Functional Study of the Two Novel Human Members of the Semaphorin Gene Family
J. Biol. Chem., September 13, 2002; 277(38): 35574 - 35585.
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GeneticsHome page
C. R. Coffman, R. C. Strohm, F. D. Oakley, Y. Yamada, D. Przychodzin, and R. E. Boswell
Identification of X-Linked Genes Required for Migration and Programmed Cell Death of Drosophila melanogaster Germ Cells
Genetics, September 1, 2002; 162(1): 273 - 284.
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DevelopmentHome page
Y. Sato, K. Yasuda, and Y. Takahashi
Morphological boundary forms by a novel inductive event mediated by Lunatic fringe and Notch during somitic segmentation
Development, August 1, 2002; 129(15): 3633 - 3644.
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BloodHome page
Y. Oike, Y. Ito, K. Hamada, X.-Q. Zhang, K. Miyata, F. Arai, T. Inada, K. Araki, N. Nakagata, M. Takeya, et al.
Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells
Blood, July 30, 2002; 100(4): 1326 - 1333.
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J. J. Munoz, L. M. Alonso-C., R. Sacedon, T. Crompton, A. Vicente, E. Jimenez, A. Varas, and A. G. Zapata
Expression and Function of the Eph A Receptors and Their Ligands Ephrins A in the Rat Thymus
J. Immunol., July 1, 2002; 169(1): 177 - 184.
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E. Trivier and T. S. Ganesan
RYK, a Catalytically Inactive Receptor Tyrosine Kinase, Associates with EphB2 and EphB3 but Does Not Interact with AF-6
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C. Gu, B. J. Limberg, G. B. Whitaker, B. Perman, D. J. Leahy, J. S. Rosenbaum, D. D. Ginty, and A. L. Kolodkin
Characterization of Neuropilin-1 Structural Features That Confer Binding to Semaphorin 3A and Vascular Endothelial Growth Factor 165
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N. Baumer, T. Marquardt, A. Stoykova, R. Ashery-Padan, K. Chowdhury, and P. Gruss
Pax6 is required for establishing naso-temporal and dorsal characteristics of the optic vesicle
Development, January 10, 2002; 129(19): 4535 - 4545.
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U. Huynh-Do, C. Vindis, H. Liu, D. P. Cerretti, J. T. McGrew, M. Enriquez, J. Chen, and T. O. Daniel
Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis
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I. D. Lawrenson, S. H. Wimmer-Kleikamp, P. Lock, S. M. Schoenwaelder, M. Down, A. W. Boyd, P. F. Alewood, and M. Lackmann
Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling
J. Cell Sci., January 3, 2002; 115(5): 1059 - 1072.
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J. P. Golding, M. Dixon, and M. Gassmann
Cues from neuroepithelium and surface ectoderm maintain neural crest-free regions within cranial mesenchyme of the developing chick
Development, January 3, 2002; 129(5): 1095 - 1105.
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E. I. Rugarli, E. Di Schiavi, M. A. Hilliard, S. Arbucci, C. Ghezzi, A. Facciolli, G. Coppola, A. Ballabio, and P. Bazzicalupo
The Kallmann syndrome gene homolog in C. elegans is involved in epidermal morphogenesis and neurite branching
Development, January 3, 2002; 129(5): 1283 - 1294.
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N. Munarini, R. Jager, S. Abderhalden, G. Zuercher, V. Rohrbach, S. Loercher, B. Pfanner-Meyer, A.-C. Andres, and A. Ziemiecki
Altered mammary epithelial development, pattern formation and involution in transgenic mice expressing the EphB4 receptor tyrosine kinase
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S. J. Fashena, M. B. Einarson, G. M. O'Neill, C. Patriotis, and E. A. Golemis
Dissection of HEF1-dependent functions in motility and transcriptional regulation
J. Cell Sci., January 1, 2002; 115(1): 99 - 111.
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R. Imondi and Z. Kaprielian
Commissural axon pathfinding on the contralateral side of the floor plate: a role for B-class ephrins in specifying the dorsoventral position of longitudinally projecting commissural axons
Development, December 1, 2001; 128(23): 4859 - 4871.
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T. Takahashi, K. Takahashi, S. Gerety, H. Wang, D. J. Anderson, and T. O. Daniel
Temporally Compartmentalized Expression of Ephrin-B2 during Renal Glomerular Development
J. Am. Soc. Nephrol., December 1, 2001; 12(12): 2673 - 2682.
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G. Jeffery
Architecture of the Optic Chiasm and the Mechanisms That Sculpt Its Development
Physiol Rev, October 1, 2001; 81(4): 1393 - 1414.
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T. Kume, H. Jiang, J. M. Topczewska, and B. L.M. Hogan
The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis
Genes & Dev., September 15, 2001; 15(18): 2470 - 2482.
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J. M. Topczewska, J. Topczewski, A. Shostak, T. Kume, L. Solnica-Krezel, and B. L.M. Hogan
The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish
Genes & Dev., September 15, 2001; 15(18): 2483 - 2493.
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BloodHome page
X.-Q. Zhang, N. Takakura, Y. Oike, T. Inada, N. W. Gale, G. D. Yancopoulos, and T. Suda
Stromal cells expressing ephrin-B2 promote the growth and sprouting of ephrin-B2+ endothelial cells
Blood, August 15, 2001; 98(4): 1028 - 1037.
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I. Stuckmann, A. Weigmann, A. Shevchenko, M. Mann, and W. B. Huttner
Ephrin B1 Is Expressed on Neuroepithelial Cells in Correlation with Neocortical Neurogenesis
J. Neurosci., April 15, 2001; 21(8): 2726 - 2737.
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J.-h. Chen, L. Wen, S. Dupuis, J. Y. Wu, and Y. Rao
The N-terminal Leucine-Rich Regions in Slit Are Sufficient To Repel Olfactory Bulb Axons and Subventricular Zone Neurons
J. Neurosci., March 1, 2001; 21(5): 1548 - 1556.
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B Knoll, K Zarbalis, W Wurst, and U Drescher
A role for the EphA family in the topographic targeting of vomeronasal axons
Development, January 3, 2001; 128(6): 895 - 906.
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J Cooke, C Moens, L Roth, L Durbin, K Shiomi, C Brennan, C Kimmel, S Wilson, and N Holder
Eph signalling functions downstream of Val to regulate cell sorting and boundary formation in the caudal hindbrain
Development, January 2, 2001; 128(4): 571 - 580.
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M. Sachs, H. Brohmann, D. Zechner, T. Muller, J. Hulsken, I. Walther, U. Schaeper, C. Birchmeier, and W. Birchmeier
Essential Role of Gab1 for Signaling by the C-Met Receptor in Vivo
J. Cell Biol., September 18, 2000; 150(6): 1375 - 1384.
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T. Nakashiba, T. Ikeda, S. Nishimura, K. Tashiro, T. Honjo, J. G. Culotti, and S. Itohara
Netrin-G1: a Novel Glycosyl Phosphatidylinositol-Linked Mammalian Netrin That Is Functionally Divergent from Classical Netrins
J. Neurosci., September 1, 2000; 20(17): 6540 - 6550.
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T. Pawson and P. Nash
Protein-protein interactions define specificity in signal transduction
Genes & Dev., May 1, 2000; 14(9): 1027 - 1047.
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C. Myers, A. Charboneau, and N. Boudreau
Homeobox B3 Promotes Capillary Morphogenesis and Angiogenesis
J. Cell Biol., January 24, 2000; 148(2): 343 - 352.
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H Paradis and R. Gendron
LIF transduces contradictory signals on capillary outgrowth through induction of stat3 and (P41/43)MAP kinase
J. Cell Sci., January 12, 2000; 113(23): 4331 - 4339.
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C. Miller, T. Schilling, K Lee, J Parker, and C. Kimmel
sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development
Development, January 9, 2000; 127(17): 3815 - 3828.
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S Orsulic and R Kemler
Expression of Eph receptors and ephrins is differentially regulated by E-cadherin
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DevelopmentHome page
R Imondi, C Wideman, and Z Kaprielian
Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons
Development, January 4, 2000; 127(7): 1397 - 1410.
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DevelopmentHome page
M Salminen, B. Meyer, E Bober, and P Gruss
Netrin 1 is required for semicircular canal formation in the mouse inner ear
Development, January 1, 2000; 127(1): 13 - 22.
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DevelopmentHome page
P. Helbling, D. Saulnier, and A. Brandli
The receptor tyrosine kinase EphB4 and ephrin-B ligands restrict angiogenic growth of embryonic veins in Xenopus laevis
Development, January 1, 2000; 127(2): 269 - 278.
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DevelopmentHome page
J. Zallen, S. Kirch, and C. Bargmann
Genes required for axon pathfinding and extension in the C. elegans nerve ring
Development, January 8, 1999; 126(16): 3679 - 3692.
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J. Biol. Chem.Home page
A. Klostermann, B. Lutz, F. Gertler, and C. Behl
The Orthologous Human and Murine Semaphorin 6A-1 Proteins (SEMA6A-1/Sema6A-1) Bind to the Enabled/Vasodilator-stimulated Phosphoprotein-like Protein (EVL) via a Novel Carboxyl-terminal Zyxin-like Domain
J. Biol. Chem., December 8, 2000; 275(50): 39647 - 39653.
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J. Biol. Chem.Home page
R. Inatome, T. Tsujimura, T. Hitomi, N. Mitsui, P. Hermann, S.'i. Kuroda, H. Yamamura, and S. Yanagi
Identification of CRAM, a Novel unc-33 Gene Family Protein That Associates with CRMP3 and Protein-tyrosine Kinase(s) in the Developing Rat Brain
J. Biol. Chem., August 25, 2000; 275(35): 27291 - 27302.
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