Transgenic rescue of congenital heart disease and spina bifida in Splotch mice

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				G. N. Corry, M. J. Hendzel, and D. A. Underhill Subnuclear localization and mobility are key indicators of PAX3 dysfunction in Waardenburg syndrome Hum. Mol. Genet., June 15, 2008; 17(12): 1825 - 1837. [Abstract] [Full Text] [PDF]

				E. Vasyutina, D. C. Lenhard, H. Wende, B. Erdmann, J. A. Epstein, and C. Birchmeier RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells PNAS, March 13, 2007; 104(11): 4443 - 4448. [Abstract] [Full Text] [PDF]

				J. Jung, T.-g. Kim, G. E. Lyons, H.-R. C. Kim, and Y. Lee Jumonji Regulates Cardiomyocyte Proliferation via Interaction with Retinoblastoma Protein J. Biol. Chem., September 2, 2005; 280(35): 30916 - 30923. [Abstract] [Full Text] [PDF]

				C. Keller, B. R. Arenkiel, C. M. Coffin, N. El-Bardeesy, R. A. DePinho, and M. R. Capecchi Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function Genes & Dev., November 1, 2004; 18(21): 2614 - 2626. [Abstract] [Full Text] [PDF]

				W. Y. Chan, C. S. Cheung, K. M. Yung, and A. J. Copp Cardiac neural crest of the mouse embryo: axial level of origin, migratory pathway and cell autonomy of the splotch (Sp2H) mutant effect Development, July 15, 2004; 131(14): 3367 - 3379. [Abstract] [Full Text] [PDF]

				R. W. Stottmann, M. Choi, Y. Mishina, E. N. Meyers, and J. Klingensmith BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium Development, May 1, 2004; 131(9): 2205 - 2218. [Abstract] [Full Text] [PDF]

				P. J. Gruber and J. A. Epstein Development Gone Awry: Congenital Heart Disease Circ. Res., February 20, 2004; 94(3): 273 - 283. [Abstract] [Full Text] [PDF]

				R. C. Milewski, N. C. Chi, J. Li, C. Brown, M. M. Lu, and J. A. Epstein Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3 Development, February 15, 2004; 131(4): 829 - 837. [Abstract] [Full Text] [PDF]

				D. Lang and J. A. Epstein Sox10 and Pax3 physically interact to mediate activation of a conserved c-RET enhancer Hum. Mol. Genet., April 15, 2003; 12(8): 937 - 945. [Abstract] [Full Text] [PDF]

				S. J. Kwang, S. M. Brugger, A. Lazik, A. E. Merrill, L.-Y. Wu, Y.-H. Liu, M. Ishii, F. O. Sangiorgi, M. Rauchman, H. M. Sucov, et al. Msx2 is an immediate downstream effector of Pax3 in the development of the murine cardiac neural crest Development, March 3, 2003; 129(2): 527 - 538. [Abstract] [Full Text] [PDF]

				I. STUCKMANN and A.B. LASSAR Erythropoietin and Retinoic Acid Signaling in the Epicardium Is Required for Cardiac Myocyte Proliferation Cold Spring Harb Symp Quant Biol, January 1, 2002; 67(0): 45 - 48. [Abstract] [PDF]

				A.D. GITLER, C.B. BROWN, L. KOCHILAS, J. LI, and J.A. EPSTEIN Neural Crest Migration and Mouse Models of Congenital Heart Disease Cold Spring Harb Symp Quant Biol, January 1, 2002; 67(0): 57 - 62. [Abstract] [PDF]

				C. B. Brown, L. Feiner, M.-M. Lu, J. Li, X. Ma, A. L. Webber, L. Jia, J. A. Raper, and J. A. Epstein PlexinA2 and semaphorin signaling during cardiac neural crest development Development, August 15, 2001; 128(16): 3071 - 3080. [Abstract] [Full Text] [PDF]

				D. E. Gutstein, G. E. Morley, H. Tamaddon, D. Vaidya, M. D. Schneider, J. Chen, K. R. Chien, H. Stuhlmann, and G. I. Fishman Conduction Slowing and Sudden Arrhythmic Death in Mice With Cardiac-Restricted Inactivation of Connexin43 Circ. Res., February 16, 2001; 88(3): 333 - 339. [Abstract] [Full Text] [PDF]

				S. J. Conway, J. Bundy, J. Chen, E. Dickman, R. Rogers, and B. M. Will Decreased neural crest stem cell expansion is responsible for the conotruncal heart defects within the Splotch (Sp2H)/Pax3 mouse mutant Cardiovasc Res, August 1, 2000; 47(2): 314 - 328. [Abstract] [Full Text] [PDF]

				J. Epstein, J Li, D Lang, F Chen, C. Brown, F Jin, M. Lu, M Thomas, E Liu, A Wessels, et al. Migration of cardiac neural crest cells in Splotch embryos Development, January 5, 2000; 127(9): 1869 - 1878. [Abstract] [PDF]

				H Brohmann, K Jagla, and C Birchmeier The role of Lbx1 in migration of muscle precursor cells Development, January 1, 2000; 127(2): 437 - 445. [Abstract] [PDF]

				L Milenkovic, L. Goodrich, K. Higgins, and M. Scott Mouse patched1 controls body size determination and limb patterning Development, January 10, 1999; 126(20): 4431 - 4440. [Abstract] [PDF]