The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo

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				M. Yamamoto, H. Beppu, K. Takaoka, C. Meno, E. Li, K. Miyazono, and H. Hamada Antagonism between Smad1 and Smad2 signaling determines the site of distal visceral endoderm formation in the mouse embryo J. Cell Biol., January 26, 2009; 184(2): 323 - 334. [Abstract] [Full Text] [PDF]

				R. Rajagopal, L. K. Dattilo, V. Kaartinen, C.-X. Deng, L. Umans, A. Zwijsen, A. B. Roberts, E. P. Bottinger, and D. C. Beebe Functions of the Type 1 BMP Receptor Acvr1 (Alk2) in Lens Development: Cell Proliferation, Terminal Differentiation, and Survival Invest. Ophthalmol. Vis. Sci., November 1, 2008; 49(11): 4953 - 4960. [Abstract] [Full Text] [PDF]

				S. Pearson, P. Sroczynska, G. Lacaud, and V. Kouskoff The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF Development, April 15, 2008; 135(8): 1525 - 1535. [Abstract] [Full Text] [PDF]

				J. Sun, H. Chen, C. Chen, J. A. Whitsett, Y. Mishina, P. Bringas Jr., J. C. Ma, D. Warburton, and W. Shi Prenatal Lung Epithelial Cell-Specific Abrogation of Alk3-Bone Morphogenetic Protein Signaling Causes Neonatal Respiratory Distress by Disrupting Distal Airway Formation Am. J. Pathol., March 1, 2008; 172(3): 571 - 582. [Abstract] [Full Text] [PDF]

				A. Di-Gregorio, M. Sancho, D. W. Stuckey, L. A. Crompton, J. Godwin, Y. Mishina, and T. A. Rodriguez BMP signalling inhibits premature neural differentiation in the mouse embryo Development, September 15, 2007; 134(18): 3359 - 3369. [Abstract] [Full Text] [PDF]

				B. van Wijk, A. F.M. Moorman, and M. J.B. van den Hoff Role of bone morphogenetic proteins in cardiac differentiation Cardiovasc Res, May 1, 2007; 74(2): 244 - 255. [Abstract] [Full Text] [PDF]

				R. Pieretti-Vanmarcke, P. K. Donahoe, L. A. Pearsall, D. M. Dinulescu, D. C. Connolly, E. F. Halpern, M. V. Seiden, and D. T. MacLaughlin Mullerian Inhibiting Substance enhances subclinical doses of chemotherapeutic agents to inhibit human and mouse ovarian cancer PNAS, November 14, 2006; 103(46): 17426 - 17431. [Abstract] [Full Text] [PDF]

				E. A. Bosman, K. A. Lawson, J. Debruyn, L. Beek, A. Francis, L. Schoonjans, D. Huylebroeck, and A. Zwijsen Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels Development, September 1, 2006; 133(17): 3399 - 3409. [Abstract] [Full Text] [PDF]

				R. L Jones, C. Stoikos, J. K Findlay, and L. A Salamonsen TGF-{beta} superfamily expression and actions in the endometrium and placenta. Reproduction, August 1, 2006; 132(2): 217 - 232. [Abstract] [Full Text] [PDF]

				C. Itman, S. Mendis, B. Barakat, and K. L. Loveland All in the family: TGF-{beta} family action in testis development. Reproduction, August 1, 2006; 132(2): 233 - 246. [Abstract] [Full Text] [PDF]

				R. Pieretti-Vanmarcke, P. K. Donahoe, P. Szotek, T. Manganaro, M. K. Lorenzen, J. Lorenzen, D. C. Connolly, E. F. Halpern, and D. T. MacLaughlin Recombinant Human Mullerian Inhibiting Substance Inhibits Long-term Growth of MIS Type II Receptor-Directed Transgenic Mouse Ovarian Cancers In vivo Clin. Cancer Res., March 1, 2006; 12(5): 1593 - 1598. [Abstract] [Full Text] [PDF]

				L. Vallier, M. Alexander, and R. A. Pedersen Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells J. Cell Sci., October 1, 2005; 118(19): 4495 - 4509. [Abstract] [Full Text] [PDF]

				T. Kunath, D. Arnaud, G. D. Uy, I. Okamoto, C. Chureau, Y. Yamanaka, E. Heard, R. L. Gardner, P. Avner, and J. Rossant Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts Development, April 1, 2005; 132(7): 1649 - 1661. [Abstract] [Full Text] [PDF]

				S. M. C. de Sousa Lopes, B. A.J. Roelen, R. M. Monteiro, R. Emmens, H. Y. Lin, E. Li, K. A. Lawson, and C. L. Mummery BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo Genes & Dev., August 1, 2004; 18(15): 1838 - 1849. [Abstract] [Full Text] [PDF]

				V. Kaartinen, M. Dudas, A. Nagy, S. Sridurongrit, M. M. Lu, and J. A. Epstein Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells Development, July 15, 2004; 131(14): 3481 - 3490. [Abstract] [Full Text] [PDF]

				R. W. Stottmann, M. Choi, Y. Mishina, E. N. Meyers, and J. Klingensmith BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium Development, May 1, 2004; 131(9): 2205 - 2218. [Abstract] [Full Text] [PDF]

				T. Ueyama, H. Kasahara, T. Ishiwata, Q. Nie, and S. Izumo Myocardin Expression Is Regulated by Nkx2.5, and Its Function Is Required for Cardiomyogenesis Mol. Cell. Biol., December 15, 2003; 23(24): 9222 - 9232. [Abstract] [Full Text] [PDF]

				H. Chang, C. W. Brown, and M. M. Matzuk Genetic Analysis of the Mammalian Transforming Growth Factor-{beta} Superfamily Endocr. Rev., December 1, 2002; 23(6): 787 - 823. [Abstract] [Full Text] [PDF]

				V. Gaussin, T. Van de Putte, Y. Mishina, M. C. Hanks, A. Zwijsen, D. Huylebroeck, R. R. Behringer, and M. D. Schneider Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3 PNAS, February 14, 2002; (2002) 42390499. [Abstract] [Full Text] [PDF]

				C. A. Ferguson, A. S. Tucker, K. Heikinheimo, M. Nomura, P. Oh, E. Li, and P. T. Sharpe The role of effectors of the activin signalling pathway, activin receptors IIA and IIB, and Smad2, in patterning of tooth development Development, November 15, 2001; 128(22): 4605 - 4613. [Abstract] [Full Text] [PDF]

				T.L. Payne, Z. Skobe, and P.C. Yelick Regulation of Tooth Development by the Novel Type I TGF{beta} Family Member Receptor Alk8 Journal of Dental Research, November 1, 2001; 80(11): 1968 - 1973. [Abstract] [PDF]

				J. Teixeira, S. Maheswaran, and P. K. Donahoe Mullerian Inhibiting Substance: An Instructive Developmental Hormone with Diagnostic and Possible Therapeutic Applications Endocr. Rev., October 1, 2001; 22(5): 657 - 674. [Abstract] [Full Text] [PDF]

				T. R. Kumar, S. Varani, N. G. Wreford, N. M. Telfer, D. M. de Kretser, and M. M. Matzuk Male Reproductive Phenotypes in Double Mutant Mice Lacking Both FSH{beta} and Activin Receptor IIA Endocrinology, August 1, 2001; 142(8): 3512 - 3518. [Abstract] [Full Text] [PDF]

				Y. Ying, X. Qi, and G.-Q. Zhao Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways PNAS, June 20, 2001; (2001) 151242798. [Abstract] [Full Text] [PDF]

				S. E. Yi, P. S. LaPolt, B. S. Yoon, J. Y.-C. Chen, J. K. H. Lu, and K. M. Lyons The type I BMP receptor BmprIB is essential for female reproductive function PNAS, June 12, 2001; (2001) 141002798. [Abstract] [Full Text] [PDF]

				J. A. Visser, R. Olaso, M. Verhoef-Post, P. Kramer, A. P. N. Themmen, and H. A. Ingraham The Serine/Threonine Transmembrane Receptor ALK2 Mediates Mullerian Inhibiting Substance Signaling Mol. Endocrinol., June 1, 2001; 15(6): 936 - 945. [Abstract] [Full Text] [PDF]

				T. R. Clarke, Y. Hoshiya, S. E. Yi, X. Liu, K. M. Lyons, and P. K. Donahoe Mullerian Inhibiting Substance Signaling Uses a Bone Morphogenetic Protein (BMP)-Like Pathway Mediated by ALK2 and Induces Smad6 Expression Mol. Endocrinol., June 1, 2001; 15(6): 946 - 959. [Abstract] [Full Text] [PDF]

				P Murray and D Edgar Regulation of the differentiation and behaviour of extra-embryonic endodermal cells by basement membranes J. Cell Sci., January 3, 2001; 114(5): 931 - 939. [Abstract] [PDF]

				K. Mintzer, M. Lee, G Runke, J Trout, M Whitman, and M. Mullins Lost-a-fin encodes a type I BMP receptor, Alk8, acting maternally and zygotically in dorsoventral pattern formation Development, January 3, 2001; 128(6): 859 - 869. [Abstract] [PDF]

				Y. Ying, X.-M. Liu, A. Marble, K. A. Lawson, and G.-Q. Zhao Requirement of Bmp8b for the Generation of Primordial Germ Cells in the Mouse Mol. Endocrinol., July 1, 2000; 14(7): 1053 - 1063. [Abstract] [Full Text]