Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Fong, G. H.
	Articles by Peng, J.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Fong, G. H.
	Articles by Peng, J.


Social Bookmarking

	What's this?

Achen, M. G., Jeltsch, M., Kukk, E., Makinen, T., Vitali, A., Wilks, A. F., Alitalo, K. and Stacker, S. A (1998). Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). Proc. Natl. Acad. Sci. USA 95, 548-553.[Abstract/Free Full Text]

Albini, A., Soldi, R., Giunciuglio, D., Giraudo, E., Benelli, R., Primo, L., Noonan, D., Salio, M., Camussi, G., Rockl, W. et al (1996). The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells. Nat. Med 2, 1371-1375.[Medline]

Baldwin, H. S., Shen, H. M., Yan, H. C., DeLisser, H. M., Chung, A., Mickanin, C., Trask, T., Kirschbaum, N. E., Newman, P. J., Albelda, S. M. et al (1994). Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development 120, 2539-2553.[Abstract/Free Full Text]

Bautch, V. L., Stanford, W. L., Rapoport, R., Russell, S., Byrum, R. S. and Futch, T. A (1996). Blood island formation in attached cultures of murine embryonic stem cells. Dev. Dyn 205, 1-12.[Medline]

Breier, G., Albrecht, U., Sterrer, S. and Risau, W (1992). Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development 114, 521-532.[Abstract]

Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Eberhardt, C. et al (1996). Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380, 435-439.[Medline]

Choi, K., Kennedy, M., Kazarov, A., Papadimitriou, J. C. and Keller, G (1998). A common precursor for hematopoietic and endothelial cells. Development 125, 725-732.[Abstract]

de Vries, C., Escobedo, J. A., Ueno, H., Houck, K., Ferrara, N. and Williams, L. T (1992). The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255, 989-991.[Abstract/Free Full Text]

Drake, C. J. and Little, C. D (1995). Exogenous vascular endothelial growth factor induces malformed and hyperfused vessels during embryonic neovascularization. Proc. Natl. Acad. Sci. USA 92, 7657-7661.[Abstract/Free Full Text]

Dumont, D. J., Fong, G. H., Puri, M. C., Gradwohl, G., Alitalo, K. and Breitman, M. L (1995). Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development. Dev. Dyn 203, 80-92.[Medline]

Dumont, D. J., Gradwohl, G., Fong, G. H., Puri, M. C., Gertsenstein, M., Auerbach, A. and Breitman, M. L (1994). Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek , reveal a critical role in vasculogenesis of the embryo. Genes Dev 8, 1897-1909.[Abstract/Free Full Text]

Ferrara, N., Carver-Moore, K., Chen, H., Dowd, M., Lu, L., O'Shea, K. S., Powell-Braxton, L., Hillan, K. J. and Moore, M. W (1996). Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380, 439-442.[Medline]

Folkman, J. and D'Amore, P. A (1996). Blood vessel formation: what is its molecular basis? [comment]. Cell 87, 1153-1155.[Medline]

Fong, G. H., Klingensmith, J., Wood, C. R., Rossant, J. and Breitman, M. L (1996). Regulation of flt-1 expression during mouse embryogenesis suggests a role in the establishment of vascular endothelium. Dev. Dyn 207, 1-10.[Medline]

Fong, G. H., Rossant, J., Gertsenstein, M. and Breitman, M. L (1995). Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376, 66-70.[Medline]

Gitay-Goren, H., Cohen, T., Tessler, S., Soker, S., Gengrinovitch, S., Rockwell, P., Klagsbrun, M., Levi, B. Z. and Neufeld, G (1996). Selective binding of VEGF121 to one of the three vascular endothelial growth factor receptors of vascular endothelial cells. J. Biol. Chem 271, 5519-5523.[Abstract/Free Full Text]

Hakem, R., de la Pompa, J. L., Sirard, C., Mo, R., Woo, M., Hakem, A.,Wakeham, A., Potter, J., Reitmair, A., Billia, F. et al (1996). The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. Cell 85, 1009-1023.[Medline]

Hiratsuka, S., Minowa, O., Kuno, J., Noda, T. and Shibuya, M (1998). Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc. Natl. Acad. Sci. USA 95, 9349-9354.[Abstract/Free Full Text]

Houck, K. A., Leung, D. W., Rowland, A. M., Winer, J. and Ferrara, N (1992). Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J. Biol. Chem 267, 26031-26037.[Abstract/Free Full Text]

Joukov, V., Pajusola, K., Kaipainen, A., Chilov, D., Lahtinen, I., Kukk, E., Saksela, O., Kalkkinen, N. and Alitalo, K (1996). A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases [published erratum appears in EMBO J 1996 Apr 1;15(7):1751]. EMBO J 15, 290-298.[Medline]

Keck, P. J., Hauser, S. D., Krivi, G., Sanzo, K., Warren, T., Feder, J. and Connolly, D. T (1989). Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 246, 1309-1312.[Abstract/Free Full Text]

Leung, D. W., Cachianes, G., Kuang, W. J., Goeddel, D. V. and Ferrara, N (1989). Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246, 1306-1309.[Abstract/Free Full Text]

Matthews, W., Jordan, C. T., Gavin, M., Jenkins, N. A., Copeland, N. G. and Lemischka, I. R (1991). A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc. Natl. Acad. Sci. USA 88, 9026-9030.[Abstract/Free Full Text]

Millauer, B., Wizigmann-Voos, S., Schnurch, H., Martinez, R., Moller, N. P., Risau, W. and Ullrich, A (1993). High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72, 835-846.[Medline]

Nishikawa, S. I., Nishikawa, S., Hirashima, M., Matsuyoshi, N. and Kodama, H (1998). Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development 125, 1747-1757.[Abstract]

Olofsson, B., Pajusola, K., Kaipainen, A., von Euler, G., Joukov, V., Saksela, O., Orpana, A., Pettersson, R. F., Alitalo, K. and Eriksson, U (1996). Vascular endothelial growth factor B, a novel growth factor for endothelial cells. Proc. Natl. Acad. Sci. USA 93, 2576-2581.[Abstract/Free Full Text]

Pardanaud, L., Yassine, F. and Dieterlen-Lievre, F (1989). Relationship between vasculogenesis, angiogenesis and haemopoiesis during avian ontogeny. Development 105, 473-485.[Abstract/Free Full Text]

Park, J. E., Chen, H. H., Winer, J., Houck, K. A. and Ferrara, N (1994). Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J. Biol. Chem 269, 25646-25654.[Abstract/Free Full Text]

Plouet, J., Moro, F., Bertagnolli, S., Coldeboeuf, N., Mazarguil, H., Clamens, S. and Bayard, F (1997). Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect. J. Biol. Chem 272, 13390-13396.[Abstract/Free Full Text]

Puri, M. C., Rossant, J., Alitalo, K., Bernstein, A. and Partanen, J (1995). The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. EMBO J 14, 5884-5891.[Medline]

Risau, W (1997). Mechanisms of angiogenesis. Nature 386, 671-674.[Medline]

Risau, W., Sariola, H., Zerwes, H. G., Sasse, J., Ekblom, P., Kemler, R. and Doetschman, T (1988). Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. Development 102, 471-478.[Abstract]

Sato, T. N., Tozawa, Y., Deutsch, U., Wolburg-Buchholz, K., Fujiwara, Y., Gendron-Maguire, M., Gridley, T., Wolburg, H., Risau, W. and Qin, Y (1995). Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 376, 70-74.[Medline]

Schuh, A. C., Faloon, P., Hu, Q. L., Bhimani, M. and Choi, K (1999). In vitro hematopoietic and endothelial potential of flk-1 (-/-) embryonic stem cells and embryos. Proc. Natl. Acad. Sci. USA 96, 2159-2164.[Abstract/Free Full Text]

Shalaby, F., Ho, J., Stanford, W. L., Fischer, K. D., Schuh, A. C., Schwartz, L., Bernstein, A. and Rossant, J (1997). A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89, 981-990.[Medline]

Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L. and Schuh, A. C (1995). Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376, 62-66.[Medline]

Shibuya, M., Yamaguchi, S., Yamane, A., Ikeda, T., Tojo, A., Matsushime, H. and Sato, M (1990). Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene ( flt ) closely related to the fms family. Oncogene 5, 519-524.[Medline]

Shima, D. T., Kuroki, M., Deutsch, U., Ng, Y. S., Adamis, A. P. and D'Amore, P. A (1996). The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences. J. Biol. Chem 271, 3877-3883.[Abstract/Free Full Text]

Soker, S., Takashima, S., Miao, H. Q., Neufeld, G. and Klagsbrun, M (1998). Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92, 735-745.[Medline]

Sugihara, T., Wadhwa, R., Kaul, S. C. and Mitsui, Y (1998). A novel alternatively spliced form of murine vascular endothelial growth factor, VEGF 115. J. Biol. Chem 273, 3033-3038.[Abstract/Free Full Text]

Thomas, P. Q., Brown, A. and Beddington, R. S (1998). Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and anearly transient marker of endothelial cell precursors. Development 125, 85-94.[Abstract]

Vittet, D., Prandini, M. H., Berthier, R., Schweitzer, A., Martin-Sisteron, H., Uzan, G. and Dejana, E (1996). Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps. Blood 88, 3424-3431.[Abstract/Free Full Text]

Wang, R., Clark, R. and Bautch, V. L (1992). Embryonic stem cell-derived cystic embryoid bodies form vascular channels: an in vitro model of blood vessel development. Development 114, 303-316.[Abstract]

Yamada, Y., Nezu, J., Shimane, M. and Hirata, Y (1997). Molecular cloning of a novel vascular endothelial growth factor, VEGF-D. Genomics 42, 483-488.[Medline]

Yamaguchi, T. P., Dumont, D. J., Conlon, R. A., Breitman, M. L. and Rossant, J (1993). flk-1 , an flt -related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development 118, 489-498.[Abstract]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

K. Yamamizu, K. Kawasaki, S. Katayama, T. Watabe, and J. K. Yamashita
Enhancement of vascular progenitor potential by protein kinase A through dual induction of Flk-1 and Neuropilin-1
Blood, October 22, 2009; 114(17): 3707 - 3716.
[Abstract] [Full Text] [PDF]

S.-W. Jin and C. Patterson
The Opening Act: Vasculogenesis and the Origins of Circulation
Arterioscler Thromb Vasc Biol, May 1, 2009; 29(5): 623 - 629.
[Abstract] [Full Text] [PDF]

N. Rahimi, T. E. Golde, and R. D. Meyer
Identification of Ligand-Induced Proteolytic Cleavage and Ectodomain Shedding of VEGFR-1/FLT1 in Leukemic Cancer Cells
Cancer Res., March 15, 2009; 69(6): 2607 - 2614.
[Abstract] [Full Text] [PDF]

D. Mariappan, J. Winkler, S. Chen, H. Schulz, J. Hescheler, and A. Sachinidis
Transcriptional profiling of CD31(+) cells isolated from murine embryonic stem cells.
Genes Cells, February 1, 2009; 14(2): 243 - 260.
[Abstract] [Full Text] [PDF]

K. Pramanik, C. Z. Chun, M. K. Garnaas, G. V. Samant, K. Li, M. A. Horswill, P. E. North, and R. Ramchandran
Dusp-5 and Snrk-1 coordinately function during vascular development and disease
Blood, January 29, 2009; 113(5): 1184 - 1191.
[Abstract] [Full Text] [PDF]

J. K. Liao
Fine-Tuning the Angiogenic Response to Vascular Endothelial Growth Factor
Circ. Res., August 1, 2008; 103(3): 229 - 230.
[Full Text] [PDF]

J.-i. Nishi, T. Minamino, H. Miyauchi, A. Nojima, K. Tateno, S. Okada, M. Orimo, J. Moriya, G.-H. Fong, K. Sunagawa, et al.
Vascular Endothelial Growth Factor Receptor-1 Regulates Postnatal Angiogenesis Through Inhibition of the Excessive Activation of Akt
Circ. Res., August 1, 2008; 103(3): 261 - 268.
[Abstract] [Full Text] [PDF]

S. Soro, A. Orecchia, L. Morbidelli, P. M. Lacal, V. Morea, K. Ballmer-Hofer, F. Ruffini, M. Ziche, S. D'Atri, G. Zambruno, et al.
A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through {alpha}5{beta}1 integrin
Blood, April 1, 2008; 111(7): 3479 - 3488.
[Abstract] [Full Text] [PDF]

M. T. Holderfield and C. C.W. Hughes
Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-{beta} in Vascular Morphogenesis
Circ. Res., March 28, 2008; 102(6): 637 - 652.
[Abstract] [Full Text] [PDF]

R. Ria, C. Piccoli, T. Cirulli, F. Falzetti, G. Mangialardi, D. Guidolin, A. Tabilio, N. Di Renzo, A. Guarini, D. Ribatti, et al.
Endothelial Differentiation of Hematopoietic Stem and Progenitor Cells from Patients with Multiple Myeloma
Clin. Cancer Res., March 15, 2008; 14(6): 1678 - 1685.
[Abstract] [Full Text] [PDF]

N. Bahary, K. Goishi, C. Stuckenholz, G. Weber, J. LeBlanc, C. A. Schafer, S. S. Berman, M. Klagsbrun, and L. I. Zon
Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish
Blood, November 15, 2007; 110(10): 3627 - 3636.
[Abstract] [Full Text] [PDF]

V. Muthig, R. Gilsbach, M. Haubold, M. Philipp, T. Ivacevic, M. Gessler, and L. Hein
Upregulation of Soluble Vascular Endothelial Growth Factor Receptor 1 Contributes to Angiogenesis Defects in the Placenta of {alpha}2B-Adrenoceptor Deficient Mice
Circ. Res., September 28, 2007; 101(7): 682 - 691.
[Abstract] [Full Text] [PDF]

T. Nakagawa
Uncoupling of the VEGF-endothelial nitric oxide axis in diabetic nephropathy: an explanation for the paradoxical effects of VEGF in renal disease
Am J Physiol Renal Physiol, June 1, 2007; 292(6): F1665 - F1672.
[Abstract] [Full Text] [PDF]

M. Abdelrahim, C. H. Baker, J. L. Abbruzzese, D. Sheikh-Hamad, S. Liu, S. D. Cho, K. Yoon, and S. Safe
Regulation of Vascular Endothelial Growth Factor Receptor-1 Expression by Specificity Proteins 1, 3, and 4 in Pancreatic Cancer Cells
Cancer Res., April 1, 2007; 67(7): 3286 - 3294.
[Abstract] [Full Text] [PDF]

R. N. Kaplan, S. Rafii, and D. Lyden
Preparing the "Soil": The Premetastatic Niche
Cancer Res., December 1, 2006; 66(23): 11089 - 11093.
[Abstract] [Full Text] [PDF]

E. Kamoshita, Y. Ikeda, M. Fujita, H. Amano, A. Oikawa, T. Suzuki, Y. Ogawa, S. Yamashina, S. Azuma, S. Narumiya, et al.
Recruitment of a Prostaglandin E Receptor Subtype, EP3-Expressing Bone Marrow Cells Is Crucial in Wound-Induced Angiogenesis
Am. J. Pathol., October 1, 2006; 169(4): 1458 - 1472.
[Abstract] [Full Text] [PDF]

S. Ahmad, P. W. Hewett, P. Wang, B. Al-Ani, M. Cudmore, T. Fujisawa, J. J. Haigh, F. le Noble, L. Wang, D. Mukhopadhyay, et al.
Direct Evidence for Endothelial Vascular Endothelial Growth Factor Receptor-1 Function in Nitric Oxide-Mediated Angiogenesis
Circ. Res., September 29, 2006; 99(7): 715 - 722.
[Abstract] [Full Text] [PDF]

A R L Medford and A B Millar
Vascular endothelial growth factor (VEGF) in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS): paradox or paradigm?
Thorax, July 1, 2006; 61(7): 621 - 626.
[Abstract] [Full Text] [PDF]

T. Wada, J. J. Haigh, M. Ema, S. Hitoshi, R. Chaddah, J. Rossant, A. Nagy, and D. van der Kooy
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival.
J. Neurosci., June 21, 2006; 26(25): 6803 - 6812.
[Abstract] [Full Text] [PDF]

L. Xu, D. M. Cochran, R. T. Tong, F. Winkler, S. Kashiwagi, R. K. Jain, and D. Fukumura
Placenta growth factor overexpression inhibits tumor growth, angiogenesis, and metastasis by depleting vascular endothelial growth factor homodimers in orthotopic mouse models.
Cancer Res., April 15, 2006; 66(8): 3971 - 3977.
[Abstract] [Full Text] [PDF]

T. Nakagawa, W. Sato, Y. Y. Sautin, O. Glushakova, B. Croker, M. A. Atkinson, C. C. Tisher, and R. J. Johnson
Uncoupling of Vascular Endothelial Growth Factor with Nitric Oxide as a Mechanism for Diabetic Vasculopathy
J. Am. Soc. Nephrol., March 1, 2006; 17(3): 736 - 745.
[Abstract] [Full Text] [PDF]

P. A. Campochiaro and the First ARVO/Pfizer Institute Working Group
Ocular versus Extraocular Neovascularization: Mirror Images or Vague Resemblances
Invest. Ophthalmol. Vis. Sci., February 1, 2006; 47(2): 462 - 474.
[Full Text] [PDF]

D. Menendez, O. Krysiak, A. Inga, B. Krysiak, M. A. Resnick, and G. Schonfelder
A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network
PNAS, January 31, 2006; 103(5): 1406 - 1411.
[Abstract] [Full Text] [PDF]

A. K. Malik, M. E. Baldwin, F. Peale, G. Fuh, W.-C. Liang, H. Lowman, G. Meng, N. Ferrara, and H.-P. Gerber
Redundant roles of VEGF-B and PlGF during selective VEGF-A blockade in mice
Blood, January 15, 2006; 107(2): 550 - 557.
[Abstract] [Full Text] [PDF]

R. D. Meyer, M. Mohammadi, and N. Rahimi
A Single Amino Acid Substitution in the Activation Loop Defines the Decoy Characteristic of VEGFR-1/FLT-1
J. Biol. Chem., January 13, 2006; 281(2): 867 - 875.
[Abstract] [Full Text] [PDF]

E. M. Morin-Kensicki, B. N. Boone, M. Howell, J. R. Stonebraker, J. Teed, J. G. Alb, T. R. Magnuson, W. O'Neal, and S. L. Milgram
Defects in Yolk Sac Vasculogenesis, Chorioallantoic Fusion, and Embryonic Axis Elongation in Mice with Targeted Disruption of Yap65
Mol. Cell. Biol., January 1, 2006; 26(1): 77 - 87.
[Abstract] [Full Text] [PDF]

M. Ema, S. Takahashi, and J. Rossant
Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors
Blood, January 1, 2006; 107(1): 111 - 117.
[Abstract] [Full Text] [PDF]

X. Gao, X. Chen, M. Taglienti, B. Rumballe, M. H. Little, and J. A. Kreidberg
Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa
Development, December 15, 2005; 132(24): 5437 - 5449.
[Abstract] [Full Text] [PDF]

A. W. Mould, S. A. Greco, M. M. Cahill, I. D. Tonks, D. Bellomo, C. Patterson, A. Zournazi, A. Nash, P. Scotney, N. K. Hayward, et al.
Transgenic Overexpression of Vascular Endothelial Growth Factor-B Isoforms by Endothelial Cells Potentiates Postnatal Vessel Growth In Vivo and In Vitro
Circ. Res., September 16, 2005; 97(6): e60 - e70.
[Abstract] [Full Text] [PDF]

L.-J. Duan, Y. Zhang-Benoit, and G.-H. Fong
Endothelium-Intrinsic Requirement for Hif-2{alpha} During Vascular Development
Circulation, May 3, 2005; 111(17): 2227 - 2232.
[Abstract] [Full Text] [PDF]

S. A. McGrath-Morrow, C. Cho, C. Cho, L. Zhen, D. J. Hicklin, and R. M. Tuder
Vascular Endothelial Growth Factor Receptor 2 Blockade Disrupts Postnatal Lung Development
Am. J. Respir. Cell Mol. Biol., May 1, 2005; 32(5): 420 - 427.
[Abstract] [Full Text] [PDF]

C. J Teng, K. Lachapelle, and R. C. Chiu
Reappraisal of Recent Clinical Trials of Angiogenic Therapy in Myocardial Ischemia
Asian Cardiovasc Thorac Ann, March 1, 2005; 13(1): 90 - 97.
[Abstract] [Full Text] [PDF]

K. Podar and K. C. Anderson
The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications
Blood, February 15, 2005; 105(4): 1383 - 1395.
[Abstract] [Full Text] [PDF]

S. Hiratsuka, Y. Kataoka, K. Nakao, K. Nakamura, S. Morikawa, S. Tanaka, M. Katsuki, Y. Maru, and M. Shibuya
Vascular Endothelial Growth Factor A (VEGF-A) Is Involved in Guidance of VEGF Receptor-Positive Cells to the Anterior Portion of Early Embryos
Mol. Cell. Biol., January 1, 2005; 25(1): 355 - 363.
[Abstract] [Full Text] [PDF]

C.N. Mowa, S. Jesmin, I. Sakuma, S. Usip, H. Togashi, M. Yoshioka, Y. Hattori, and R. Papka
Characterization of Vascular Endothelial Growth Factor (VEGF) in the Uterine Cervix over Pregnancy: Effects of Denervation and Implications for Cervical Ripening
J. Histochem. Cytochem., December 1, 2004; 52(12): 1665 - 1674.
[Abstract] [Full Text] [PDF]

K. Nakamura, A. Yamamoto, M. Kamishohara, K. Takahashi, E. Taguchi, T. Miura, K. Kubo, M. Shibuya, and T. Isoe
KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth
Mol. Cancer Ther., December 1, 2004; 3(12): 1639 - 1649.
[Abstract] [Full Text] [PDF]

M. Mura, C. C. dos Santos, D. Stewart, and M. Liu
Vascular endothelial growth factor and related molecules in acute lung injury
J Appl Physiol, November 1, 2004; 97(5): 1605 - 1617.
[Abstract] [Full Text] [PDF]

I. NILSSON, C. ROLNY, Y. WU, B. PYTOWSKI, D. HICKLIN, K. ALITALO, L. CLAESSON-WELSH, and S. WENNSTROM
Vascular endothelial growth factor receptor-3 in hypoxia-induced vascular development
FASEB J, October 1, 2004; 18(13): 1507 - 1515.
[Abstract] [Full Text] [PDF]

J.-C. Tille and M.S. Pepper
Hereditary Vascular Anomalies: New Insights Into Their Pathogenesis
Arterioscler Thromb Vasc Biol, September 1, 2004; 24(9): 1578 - 1590.
[Abstract] [Full Text] [PDF]

S. A. Vokes, T. A. Yatskievych, R. L. Heimark, J. McMahon, A. P. McMahon, P. B. Antin, and P. A. Krieg
Hedgehog signaling is essential for endothelial tube formation during vasculogenesis
Development, September 1, 2004; 131(17): 4371 - 4380.
[Abstract] [Full Text] [PDF]

N. Ferrara
Vascular Endothelial Growth Factor: Basic Science and Clinical Progress
Endocr. Rev., August 1, 2004; 25(4): 581 - 611.
[Abstract] [Full Text] [PDF]

J. B. Kearney, N. C. Kappas, C. Ellerstrom, F. W. DiPaola, and V. L. Bautch
The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis
Blood, June 15, 2004; 103(12): 4527 - 4535.
[Abstract] [Full Text] [PDF]

L. Ye, H. K Haider, S.-J. Jiang, and E. K. Sim
Therapeutic Angiogenesis Using Vascular Endothelial Growth Factor
Asian Cardiovasc Thorac Ann, June 1, 2004; 12(2): 173 - 181.
[Abstract] [Full Text] [PDF]

C. Park, I. Afrikanova, Y. S. Chung, W. J. Zhang, E. Arentson, G. h. Fong, A. Rosendahl, and K. Choi
A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells
Development, June 1, 2004; 131(11): 2749 - 2762.
[Abstract] [Full Text] [PDF]

Y. Sassa, Y. Hata, L. P. Aiello, Y. Taniguchi, K. Kohno, and T. Ishibashi
Bifunctional Properties of Peroxisome Proliferator-Activated Receptor {gamma}1 in KDR Gene Regulation Mediated via Interaction With Both Sp1 and Sp3
Diabetes, May 1, 2004; 53(5): 1222 - 1229.
[Abstract] [Full Text] [PDF]

D. M. Roberts, J. B. Kearney, J. H. Johnson, M. P. Rosenberg, R. Kumar, and V. L. Bautch
The Vascular Endothelial Growth Factor (VEGF) Receptor Flt-1 (VEGFR-1) Modulates Flk-1 (VEGFR-2) Signaling During Blood Vessel Formation
Am. J. Pathol., May 1, 2004; 164(5): 1531 - 1535.
[Abstract] [Full Text] [PDF]

L.-J. Duan, A. Imamoto, and G.-H. Fong
Dual roles of the C-terminal Src kinase (Csk) during developmental vascularization
Blood, February 15, 2004; 103(4): 1370 - 1372.
[Abstract] [Full Text] [PDF]

J. J. Haigh, M. Ema, K. Haigh, M. Gertsenstein, P. Greer, J. Rossant, A. Nagy, and E. F. Wagner
Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells
Blood, February 1, 2004; 103(3): 912 - 920.
[Abstract] [Full Text] [PDF]

F. Mac Gabhann and A. S. Popel
Model of competitive binding of vascular endothelial growth factor and placental growth factor to VEGF receptors on endothelial cells
Am J Physiol Heart Circ Physiol, January 1, 2004; 286(1): H153 - H164.
[Abstract] [Full Text] [PDF]

M. Hirashima, Y. Lu, L. Byers, and J. Rossant
Trophoblast expression of fms-like tyrosine kinase 1 is not required for the establishment of the maternal-fetal interface in the mouse placenta
PNAS, December 23, 2003; 100(26): 15637 - 15642.
[Abstract] [Full Text] [PDF]

X. Jiang and J. R. Couchman
Perlecan and Tumor Angiogenesis
J. Histochem. Cytochem., November 1, 2003; 51(11): 1393 - 1410.
[Abstract] [Full Text] [PDF]

Y.-B. Shui, X. Wang, J. S. Hu, S.-P. Wang, C. M. Garcia, J. D. Potts, Y. Sharma, and D. C. Beebe
Vascular Endothelial Growth Factor Expression and Signaling in the Lens
Invest. Ophthalmol. Vis. Sci., September 1, 2003; 44(9): 3911 - 3919.
[Abstract] [Full Text] [PDF]

A. Orecchia, P. M. Lacal, C. Schietroma, V. Morea, G. Zambruno, and C. M. Failla
Vascular endothelial growth factor receptor-1 is deposited in the extracellular matrix by endothelial cells and is a ligand for the {alpha}5{beta}1 integrin
J. Cell Sci., September 1, 2003; 116(17): 3479 - 3489.
[Abstract] [Full Text] [PDF]

Y. Wu, M. Moser, V. L. Bautch, and C. Patterson
HoxB5 Is an Upstream Transcriptional Switch for Differentiation of the Vascular Endothelium from Precursor Cells
Mol. Cell. Biol., August 15, 2003; 23(16): 5680 - 5691.
[Abstract] [Full Text] [PDF]

Y.-s. Yoon and D. W. Losordo
All in the Family: VEGF-B Joins the Ranks of Proangiogenic Cytokines
Circ. Res., July 25, 2003; 93(2): 87 - 90.
[Full Text] [PDF]

G. E. Hosford and D. M. Olson
Effects of hyperoxia on VEGF, its receptors, and HIF-2{alpha} in the newborn rat lung
Am J Physiol Lung Cell Mol Physiol, July 1, 2003; 285(1): L161 - L168.
[Abstract] [Full Text] [PDF]

M. Hirashima, M. Ogawa, S. Nishikawa, K. Matsumura, K. Kawasaki, M. Shibuya, and S.-I. Nishikawa
A chemically defined culture of VEGFR2+ cells derived from embryonic stem cells reveals the role of VEGFR1 in tuning the threshold for VEGF in developing endothelial cells
Blood, March 15, 2003; 101(6): 2261 - 2267.
[Abstract] [Full Text] [PDF]

A. Damert, L. Miquerol, M. Gertsenstein, W. Risau, and A. Nagy
Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation
Development, March 6, 2003; 129(8): 1881 - 1892.
[Abstract] [Full Text] [PDF]

H. Kubo and K. Alitalo
The bloody fate of endothelial stem cells
Genes & Dev., February 1, 2003; 17(3): 322 - 329.
[Full Text] [PDF]

T. P. Boesen, B. Soni, T. W. Schwartz, and T. Halkier
Single-chain Vascular Endothelial Growth Factor Variant with Antagonist Activity
J. Biol. Chem., October 18, 2002; 277(43): 40335 - 40341.
[Abstract] [Full Text] [PDF]

L. Jussila and K. Alitalo
Vascular Growth Factors and Lymphangiogenesis
Physiol Rev, July 1, 2002; 82(3): 673 - 700.
[Abstract] [Full Text] [PDF]

J. B. Kearney, C. A. Ambler, K.-A. Monaco, N. Johnson, R. G. Rapoport, and V. L. Bautch
Vascular endothelial growth factor receptor Flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division
Blood, April 1, 2002; 99(7): 2397 - 2407.
[Abstract] [Full Text] [PDF]

P. Guo, L. Xu, S. Pan, R. A. Brekken, S.-T. Yang, G. B. Whitaker, M. Nagane, P. E. Thorpe, J. S. Rosenbaum, H.-J. Su Huang, et al.
Vascular Endothelial Growth Factor Isoforms Display Distinct Activities in Promoting Tumor Angiogenesis at Different Anatomic Sites
Cancer Res., December 1, 2001; 61(23): 8569 - 8577.
[Abstract] [Full Text] [PDF]

B. Bussolati, C. Dunk, M. Grohman, C. D. Kontos, J. Mason, and A. Ahmed
Vascular Endothelial Growth Factor Receptor-1 Modulates Vascular Endothelial Growth Factor-Mediated Angiogenesis via Nitric Oxide
Am. J. Pathol., September 1, 2001; 159(3): 993 - 1008.
[Abstract] [Full Text] [PDF]

S. Soker, M. Kaefer, M. Johnson, M. Klagsbrun, A. Atala, and M. R. Freeman
Vascular Endothelial Growth Factor-Mediated Autocrine Stimulation of Prostate Tumor Cells Coincides with Progression to a Malignant Phenotype
Am. J. Pathol., August 1, 2001; 159(2): 651 - 659.
[Abstract] [Full Text]

K. Aase, G. von Euler, X. Li, A. Ponten, P. Thoren, R. Cao, Y. Cao, B. Olofsson, S. Gebre-Medhin, M. Pekny, et al.
Vascular Endothelial Growth Factor-B-Deficient Mice Display an Atrial Conduction Defect
Circulation, July 17, 2001; 104(3): 358 - 364.
[Abstract] [Full Text] [PDF]

N. Ferrara
Role of vascular endothelial growth factor in regulation of physiological angiogenesis
Am J Physiol Cell Physiol, June 1, 2001; 280(6): C1358 - C1366.
[Abstract] [Full Text] [PDF]

I. Zachary
Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor
Am J Physiol Cell Physiol, June 1, 2001; 280(6): C1375 - C1386.
[Abstract] [Full Text] [PDF]

K. ILJIN, M. J. KARKKAINEN, E. C. LAWRENCE, M. A. KIMAK, M. UUTELA, J. TAIPALE KATRI PAJUSOLA LEENA ALHONEN, M. HALMEKYTO, D. N. FINEGOLD, R. E. FERRELL, and K. ALITALO
VEGFR3 gene structure, regulatory region, and sequence polymorphisms
FASEB J, April 1, 2001; 15(6): 1028 - 1036.
[Abstract] [Full Text] [PDF]

E. M. Conway, D. Collen, and P. Carmeliet
Molecular mechanisms of blood vessel growth
Cardiovasc Res, February 16, 2001; 49(3): 507 - 521.
[Full Text] [PDF]

C. Robinson and S. Stringer
The splice variants of vascular endothelial growth factor (VEGF) and their receptors
J. Cell Sci., January 3, 2001; 114(5): 853 - 865.
[Abstract] [PDF]

M Mahlapuu, M Ormestad, S Enerback, and P Carlsson
The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm
Development, January 1, 2001; 128(2): 155 - 166.
[Abstract] [PDF]

K. Hamada, Y. Oike, N. Takakura, Y. Ito, L. Jussila, D. J. Dumont, K. Alitalo, and T. Suda
VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis
Blood, December 1, 2000; 96(12): 3793 - 3800.
[Abstract] [Full Text] [PDF]

R. A. Brekken, J. P. Overholser, V. A. Stastny, J. Waltenberger, J. D. Minna, and P. E. Thorpe
Selective Inhibition of Vascular Endothelial Growth Factor (VEGF) Receptor 2 (KDR/Flk-1) Activity by a Monoclonal Anti-VEGF Antibody Blocks Tumor Growth in Mice
Cancer Res., September 1, 2000; 60(18): 5117 - 5124.
[Abstract] [Full Text]

A. Saaristo, T. A. Partanen, J. Arola, L. Jussila, M. Hytonen, A. Makitie, S. Vento, A. Kaipainen, H. Malmberg, and K. Alitalo
Vascular Endothelial Growth Factor-C and Its Receptor VEGFR-3 in the Nasal Mucosa and in Nasopharyngeal Tumors
Am. J. Pathol., July 1, 2000; 157(1): 7 - 14.
[Abstract] [Full Text] [PDF]

S. J. Mandriota, C. Pyke, C. Di Sanza, P. Quinodoz, B. Pittet, and M. S. Pepper
Hypoxia-Inducible Angiopoietin-2 Expression Is Mimicked by Iodonium Compounds and Occurs in the Rat Brain and Skin in Response to Systemic Hypoxia and Tissue Ischemia
Am. J. Pathol., June 1, 2000; 156(6): 2077 - 2089.
[Abstract] [Full Text] [PDF]

F. Vidal, J. Aragones, A. Alfranca, and M. O. de Landazuri
Up-regulation of vascular endothelial growth factor receptor Flt-1 after endothelial denudation: role of transcription factor Egr-1
Blood, June 1, 2000; 95(11): 3387 - 3395.
[Abstract] [Full Text] [PDF]

L Miquerol, B. Langille, and A Nagy
Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression
Development, January 9, 2000; 127(18): 3941 - 3946.
[Abstract] [PDF]

T. Veikkola, M. Karkkainen, L. Claesson-Welsh, and K. Alitalo
Regulation of Angiogenesis via Vascular Endothelial Growth Factor Receptors
Cancer Res., January 1, 2000; 60(2): 203 - 212.
[Full Text]

N. Rahimi, V. Dayanir, and K. Lashkari
Receptor Chimeras Indicate That the Vascular Endothelial Growth Factor Receptor-1 (VEGFR-1) Modulates Mitogenic Activity of VEGFR-2 in Endothelial Cells
J. Biol. Chem., May 26, 2000; 275(22): 16986 - 16992.
[Abstract] [Full Text] [PDF]

H. Gille, J. Kowalski, B. Li, J. LeCouter, B. Moffat, T. F. Zioncheck, N. Pelletier, and N. Ferrara
Analysis of Biological Effects and Signaling Properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A REASSESSMENT USING NOVEL RECEPTOR-SPECIFIC VASCULAR ENDOTHELIAL GROWTH FACTOR MUTANTS
J. Biol. Chem., January 26, 2001; 276(5): 3222 - 3230.
[Abstract] [Full Text] [PDF]

V. Dayanir, R. D. Meyer, K. Lashkari, and N. Rahimi
Identification of Tyrosine Residues in Vascular Endothelial Growth Factor Receptor-2/FLK-1 Involved in Activation of Phosphatidylinositol 3-Kinase and Cell Proliferation
J. Biol. Chem., May 18, 2001; 276(21): 17686 - 17692.
[Abstract] [Full Text] [PDF]

G. B. Whitaker, B. J. Limberg, and J. S. Rosenbaum
Vascular Endothelial Growth Factor Receptor-2 and Neuropilin-1 Form a Receptor Complex That Is Responsible for the Differential Signaling Potency of VEGF165 and VEGF121
J. Biol. Chem., June 29, 2001; 276(27): 25520 - 25531.
[Abstract] [Full Text] [PDF]

J. Peng, L. Zhang, L. Drysdale, and G.-H. Fong
The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling
PNAS, July 18, 2000; 97(15): 8386 - 8391.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Fong, G. H.

Articles by Peng, J.

Search for Related Content

PubMed

PubMed Citation

Articles by Fong, G. H.

Articles by Peng, J.

Social Bookmarking

What's this?

				S.-W. Jin and C. Patterson The Opening Act: Vasculogenesis and the Origins of Circulation Arterioscler Thromb Vasc Biol, May 1, 2009; 29(5): 623 - 629. [Abstract] [Full Text] [PDF]

				N. Rahimi, T. E. Golde, and R. D. Meyer Identification of Ligand-Induced Proteolytic Cleavage and Ectodomain Shedding of VEGFR-1/FLT1 in Leukemic Cancer Cells Cancer Res., March 15, 2009; 69(6): 2607 - 2614. [Abstract] [Full Text] [PDF]

				D. Mariappan, J. Winkler, S. Chen, H. Schulz, J. Hescheler, and A. Sachinidis Transcriptional profiling of CD31(+) cells isolated from murine embryonic stem cells. Genes Cells, February 1, 2009; 14(2): 243 - 260. [Abstract] [Full Text] [PDF]

				K. Pramanik, C. Z. Chun, M. K. Garnaas, G. V. Samant, K. Li, M. A. Horswill, P. E. North, and R. Ramchandran Dusp-5 and Snrk-1 coordinately function during vascular development and disease Blood, January 29, 2009; 113(5): 1184 - 1191. [Abstract] [Full Text] [PDF]

				J. K. Liao Fine-Tuning the Angiogenic Response to Vascular Endothelial Growth Factor Circ. Res., August 1, 2008; 103(3): 229 - 230. [Full Text] [PDF]

				J.-i. Nishi, T. Minamino, H. Miyauchi, A. Nojima, K. Tateno, S. Okada, M. Orimo, J. Moriya, G.-H. Fong, K. Sunagawa, et al. Vascular Endothelial Growth Factor Receptor-1 Regulates Postnatal Angiogenesis Through Inhibition of the Excessive Activation of Akt Circ. Res., August 1, 2008; 103(3): 261 - 268. [Abstract] [Full Text] [PDF]

				S. Soro, A. Orecchia, L. Morbidelli, P. M. Lacal, V. Morea, K. Ballmer-Hofer, F. Ruffini, M. Ziche, S. D'Atri, G. Zambruno, et al. A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through {alpha}5{beta}1 integrin Blood, April 1, 2008; 111(7): 3479 - 3488. [Abstract] [Full Text] [PDF]

				M. T. Holderfield and C. C.W. Hughes Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-{beta} in Vascular Morphogenesis Circ. Res., March 28, 2008; 102(6): 637 - 652. [Abstract] [Full Text] [PDF]

				R. Ria, C. Piccoli, T. Cirulli, F. Falzetti, G. Mangialardi, D. Guidolin, A. Tabilio, N. Di Renzo, A. Guarini, D. Ribatti, et al. Endothelial Differentiation of Hematopoietic Stem and Progenitor Cells from Patients with Multiple Myeloma Clin. Cancer Res., March 15, 2008; 14(6): 1678 - 1685. [Abstract] [Full Text] [PDF]

				N. Bahary, K. Goishi, C. Stuckenholz, G. Weber, J. LeBlanc, C. A. Schafer, S. S. Berman, M. Klagsbrun, and L. I. Zon Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish Blood, November 15, 2007; 110(10): 3627 - 3636. [Abstract] [Full Text] [PDF]

				V. Muthig, R. Gilsbach, M. Haubold, M. Philipp, T. Ivacevic, M. Gessler, and L. Hein Upregulation of Soluble Vascular Endothelial Growth Factor Receptor 1 Contributes to Angiogenesis Defects in the Placenta of {alpha}2B-Adrenoceptor Deficient Mice Circ. Res., September 28, 2007; 101(7): 682 - 691. [Abstract] [Full Text] [PDF]

				T. Nakagawa Uncoupling of the VEGF-endothelial nitric oxide axis in diabetic nephropathy: an explanation for the paradoxical effects of VEGF in renal disease Am J Physiol Renal Physiol, June 1, 2007; 292(6): F1665 - F1672. [Abstract] [Full Text] [PDF]

				M. Abdelrahim, C. H. Baker, J. L. Abbruzzese, D. Sheikh-Hamad, S. Liu, S. D. Cho, K. Yoon, and S. Safe Regulation of Vascular Endothelial Growth Factor Receptor-1 Expression by Specificity Proteins 1, 3, and 4 in Pancreatic Cancer Cells Cancer Res., April 1, 2007; 67(7): 3286 - 3294. [Abstract] [Full Text] [PDF]

				R. N. Kaplan, S. Rafii, and D. Lyden Preparing the "Soil": The Premetastatic Niche Cancer Res., December 1, 2006; 66(23): 11089 - 11093. [Abstract] [Full Text] [PDF]

				E. Kamoshita, Y. Ikeda, M. Fujita, H. Amano, A. Oikawa, T. Suzuki, Y. Ogawa, S. Yamashina, S. Azuma, S. Narumiya, et al. Recruitment of a Prostaglandin E Receptor Subtype, EP3-Expressing Bone Marrow Cells Is Crucial in Wound-Induced Angiogenesis Am. J. Pathol., October 1, 2006; 169(4): 1458 - 1472. [Abstract] [Full Text] [PDF]

				S. Ahmad, P. W. Hewett, P. Wang, B. Al-Ani, M. Cudmore, T. Fujisawa, J. J. Haigh, F. le Noble, L. Wang, D. Mukhopadhyay, et al. Direct Evidence for Endothelial Vascular Endothelial Growth Factor Receptor-1 Function in Nitric Oxide-Mediated Angiogenesis Circ. Res., September 29, 2006; 99(7): 715 - 722. [Abstract] [Full Text] [PDF]

				A R L Medford and A B Millar Vascular endothelial growth factor (VEGF) in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS): paradox or paradigm? Thorax, July 1, 2006; 61(7): 621 - 626. [Abstract] [Full Text] [PDF]

				T. Wada, J. J. Haigh, M. Ema, S. Hitoshi, R. Chaddah, J. Rossant, A. Nagy, and D. van der Kooy Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival. J. Neurosci., June 21, 2006; 26(25): 6803 - 6812. [Abstract] [Full Text] [PDF]

				L. Xu, D. M. Cochran, R. T. Tong, F. Winkler, S. Kashiwagi, R. K. Jain, and D. Fukumura Placenta growth factor overexpression inhibits tumor growth, angiogenesis, and metastasis by depleting vascular endothelial growth factor homodimers in orthotopic mouse models. Cancer Res., April 15, 2006; 66(8): 3971 - 3977. [Abstract] [Full Text] [PDF]

				T. Nakagawa, W. Sato, Y. Y. Sautin, O. Glushakova, B. Croker, M. A. Atkinson, C. C. Tisher, and R. J. Johnson Uncoupling of Vascular Endothelial Growth Factor with Nitric Oxide as a Mechanism for Diabetic Vasculopathy J. Am. Soc. Nephrol., March 1, 2006; 17(3): 736 - 745. [Abstract] [Full Text] [PDF]

				P. A. Campochiaro and the First ARVO/Pfizer Institute Working Group Ocular versus Extraocular Neovascularization: Mirror Images or Vague Resemblances Invest. Ophthalmol. Vis. Sci., February 1, 2006; 47(2): 462 - 474. [Full Text] [PDF]

				D. Menendez, O. Krysiak, A. Inga, B. Krysiak, M. A. Resnick, and G. Schonfelder A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network PNAS, January 31, 2006; 103(5): 1406 - 1411. [Abstract] [Full Text] [PDF]

				A. K. Malik, M. E. Baldwin, F. Peale, G. Fuh, W.-C. Liang, H. Lowman, G. Meng, N. Ferrara, and H.-P. Gerber Redundant roles of VEGF-B and PlGF during selective VEGF-A blockade in mice Blood, January 15, 2006; 107(2): 550 - 557. [Abstract] [Full Text] [PDF]

				R. D. Meyer, M. Mohammadi, and N. Rahimi A Single Amino Acid Substitution in the Activation Loop Defines the Decoy Characteristic of VEGFR-1/FLT-1 J. Biol. Chem., January 13, 2006; 281(2): 867 - 875. [Abstract] [Full Text] [PDF]

				E. M. Morin-Kensicki, B. N. Boone, M. Howell, J. R. Stonebraker, J. Teed, J. G. Alb, T. R. Magnuson, W. O'Neal, and S. L. Milgram Defects in Yolk Sac Vasculogenesis, Chorioallantoic Fusion, and Embryonic Axis Elongation in Mice with Targeted Disruption of Yap65 Mol. Cell. Biol., January 1, 2006; 26(1): 77 - 87. [Abstract] [Full Text] [PDF]

				M. Ema, S. Takahashi, and J. Rossant Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors Blood, January 1, 2006; 107(1): 111 - 117. [Abstract] [Full Text] [PDF]

				X. Gao, X. Chen, M. Taglienti, B. Rumballe, M. H. Little, and J. A. Kreidberg Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa Development, December 15, 2005; 132(24): 5437 - 5449. [Abstract] [Full Text] [PDF]

				A. W. Mould, S. A. Greco, M. M. Cahill, I. D. Tonks, D. Bellomo, C. Patterson, A. Zournazi, A. Nash, P. Scotney, N. K. Hayward, et al. Transgenic Overexpression of Vascular Endothelial Growth Factor-B Isoforms by Endothelial Cells Potentiates Postnatal Vessel Growth In Vivo and In Vitro Circ. Res., September 16, 2005; 97(6): e60 - e70. [Abstract] [Full Text] [PDF]

				L.-J. Duan, Y. Zhang-Benoit, and G.-H. Fong Endothelium-Intrinsic Requirement for Hif-2{alpha} During Vascular Development Circulation, May 3, 2005; 111(17): 2227 - 2232. [Abstract] [Full Text] [PDF]

				S. A. McGrath-Morrow, C. Cho, C. Cho, L. Zhen, D. J. Hicklin, and R. M. Tuder Vascular Endothelial Growth Factor Receptor 2 Blockade Disrupts Postnatal Lung Development Am. J. Respir. Cell Mol. Biol., May 1, 2005; 32(5): 420 - 427. [Abstract] [Full Text] [PDF]