Sonic hedgehog regulates the growth and patterning of the cerebellum

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Plexin-B2, But Not Plexin-B1, Critically Modulates Neuronal Migration and Patterning of the Developing Nervous System In Vivo
J. Neurosci., June 6, 2007; 27(23): 6333 - 6347.
[Abstract] [Full Text] [PDF]

T. D. McCall, C. A. Pedone, and D. W. Fults
Apoptosis Suppression by Somatic Cell Transfer of Bcl-2 Promotes Sonic Hedgehog-Dependent Medulloblastoma Formation in Mice
Cancer Res., June 1, 2007; 67(11): 5179 - 5185.
[Abstract] [Full Text] [PDF]

F. Balordi and G. Fishell
Hedgehog Signaling in the Subventricular Zone Is Required for Both the Maintenance of Stem Cells and the Migration of Newborn Neurons
J. Neurosci., May 30, 2007; 27(22): 5936 - 5947.
[Abstract] [Full Text] [PDF]

C. Vaillant, O. Michos, S. Orolicki, F. Brellier, S. Taieb, E. Moreno, H. Te, R. Zeller, and D. Monard
Protease nexin 1 and its receptor LRP modulate SHH signalling during cerebellar development
Development, May 1, 2007; 134(9): 1745 - 1754.
[Abstract] [Full Text] [PDF]

R. H. Friedel, G. Kerjan, H. Rayburn, U. Schuller, C. Sotelo, M. Tessier-Lavigne, and A. Chedotal
Plexin-B2 Controls the Development of Cerebellar Granule Cells
J. Neurosci., April 4, 2007; 27(14): 3921 - 3932.
[Abstract] [Full Text] [PDF]

B. Stecca, C. Mas, V. Clement, M. Zbinden, R. Correa, V. Piguet, F. Beermann, and A. Ruiz i Altaba
Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways
PNAS, April 3, 2007; 104(14): 5895 - 5900.
[Abstract] [Full Text] [PDF]

W. A. Alcaraz, D. A. Gold, E. Raponi, P. M. Gent, D. Concepcion, and B. A. Hamilton
Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation
PNAS, December 19, 2006; 103(51): 19424 - 19429.
[Abstract] [Full Text] [PDF]

B. A. Hatton, P. S. Knoepfler, A. M. Kenney, D. H. Rowitch, I. M. de Alboran, J. M. Olson, and R. N. Eisenman
N-myc Is an Essential Downstream Effector of Shh Signaling during both Normal and Neoplastic Cerebellar Growth.
Cancer Res., September 1, 2006; 66(17): 8655 - 8661.
[Abstract] [Full Text] [PDF]

J. D. Corrales, S. Blaess, E. M. Mahoney, and A. L. Joyner
The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation
Development, May 1, 2006; 133(9): 1811 - 1821.
[Abstract] [Full Text] [PDF]

S. R. Browd, A. M. Kenney, O. N. Gottfried, J. W. Yoon, D. Walterhouse, C. A. Pedone, and D. W. Fults
N-myc Can Substitute for Insulin-Like Growth Factor Signaling in a Mouse Model of Sonic Hedgehog-Induced Medulloblastoma.
Cancer Res., March 1, 2006; 66(5): 2666 - 2672.
[Abstract] [Full Text] [PDF]

J. Cayuso, F. Ulloa, B. Cox, J. Briscoe, and E. Marti
The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity
Development, February 1, 2006; 133(3): 517 - 528.
[Abstract] [Full Text] [PDF]

R. J. Roper, L. L. Baxter, N. G. Saran, D. K. Klinedinst, P. A. Beachy, and R. H. Reeves
Defective cerebellar response to mitogenic Hedgehog signaling in Down's syndrome mice
PNAS, January 31, 2006; 103(5): 1452 - 1456.
[Abstract] [Full Text] [PDF]

J. Mills, A. Niewmierzycka, A. Oloumi, B. Rico, R. St-Arnaud, I. R. Mackenzie, N. M. Mawji, J. Wilson, L. F. Reichardt, and S. Dedhar
Critical Role of Integrin-Linked Kinase in Granule Cell Precursor Proliferation and Cerebellar Development
J. Neurosci., January 18, 2006; 26(3): 830 - 840.
[Abstract] [Full Text] [PDF]

K. Nagao, N. Togawa, K. Fujii, H. Uchikawa, Y. Kohno, M. Yamada, and T. Miyashita
Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarrays
Hum. Mol. Genet., November 15, 2005; 14(22): 3379 - 3388.
[Abstract] [Full Text] [PDF]

Y. Choi, P. R. Borghesani, J. A. Chan, and R. A. Segal
Migration from a Mitogenic Niche Promotes Cell-Cycle Exit
J. Neurosci., November 9, 2005; 25(45): 10437 - 10445.
[Abstract] [Full Text] [PDF]

C. M. Louie and J. G. Gleeson
Genetic basis of Joubert syndrome and related disorders of cerebellar development
Hum. Mol. Genet., October 15, 2005; 14(suppl_2): R235 - R242.
[Abstract] [Full Text] [PDF]

C. Klein, S. J. B. Butt, R. P. Machold, J. E. Johnson, and G. Fishell
Cerebellum- and forebrain-derived stem cells possess intrinsic regional character
Development, October 15, 2005; 132(20): 4497 - 4508.
[Abstract] [Full Text] [PDF]

B. Argenti, R. Gallo, L. Di Marcotullio, E. Ferretti, M. Napolitano, S. Canterini, E. De Smaele, A. Greco, M. T. Fiorenza, M. Maroder, et al.
Hedgehog Antagonist RENKCTD11 Regulates Proliferation and Apoptosis of Developing Granule Cell Progenitors
J. Neurosci., September 7, 2005; 25(36): 8338 - 8346.
[Abstract] [Full Text] [PDF]

J. L. Close, B. Gumuscu, and T. A. Reh
Retinal neurons regulate proliferation of postnatal progenitors and Muller glia in the rat retina via TGF{beta} signaling
Development, July 1, 2005; 132(13): 3015 - 3026.
[Abstract] [Full Text] [PDF]

S. W.M. Bruggeman, M. E. Valk-Lingbeek, P. P.M. van der Stoop, J. J.L. Jacobs, K. Kieboom, E. Tanger, D. Hulsman, C. Leung, Y. Arsenijevic, S. Marino, et al.
Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice
Genes & Dev., June 15, 2005; 19(12): 1438 - 1443.
[Abstract] [Full Text] [PDF]

V. Palma, D. A. Lim, N. Dahmane, P. Sanchez, T. C. Brionne, C. D. Herzberg, Y. Gitton, A. Carleton, A. Alvarez-Buylla, and A. R. i Altaba
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain
Development, January 15, 2005; 132(2): 335 - 344.
[Abstract] [Full Text] [PDF]

A. M. Canudas, V. Di Giorgi-Gerevini, L. Iacovelli, G. Nano, M. D'Onofrio, A. Arcella, F. Giangaspero, C. Busceti, L. Ricci-Vitiani, G. Battaglia, et al.
PHCCC, a Specific Enhancer of Type 4 Metabotropic Glutamate Receptors, Reduces Proliferation and Promotes Differentiation of Cerebellar Granule Cell Neuroprecursors
J. Neurosci., November 17, 2004; 24(46): 10343 - 10352.
[Abstract] [Full Text] [PDF]

J. D. Corrales, G. L. Rocco, S. Blaess, Q. Guo, and A. L. Joyner
Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development
Development, November 15, 2004; 131(22): 5581 - 5590.
[Abstract] [Full Text] [PDF]

H. Miura, H. Kato, Y. Kusakabe, M. Tagami, J. Miura-Ohnuma, Y. Ninomiya, and A. Hino
A Strong Nerve Dependence of Sonic hedgehog Expression in Basal Cells in Mouse Taste Bud and an Autonomous Transcriptional Control of Genes in Differentiated Taste Cells
Chem Senses, November 1, 2004; 29(9): 823 - 831.
[Abstract] [Full Text] [PDF]

L. Di Marcotullio, E. Ferretti, E. De Smaele, B. Argenti, C. Mincione, F. Zazzeroni, R. Gallo, L. Masuelli, M. Napolitano, M. Maroder, et al.
RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
PNAS, July 20, 2004; 101(29): 10833 - 10838.
[Abstract] [Full Text] [PDF]

I. Rios, R. Alvarez-Rodriguez, E. Marti, and S. Pons
Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling
Development, July 1, 2004; 131(13): 3159 - 3168.

				M. Komada, H. Saitsu, M. Kinboshi, T. Miura, K. Shiota, and M. Ishibashi Hedgehog signaling is involved in development of the neocortex Development, August 15, 2008; 135(16): 2717 - 2727. [Abstract] [Full Text] [PDF]

				S. Blaess, D. Stephen, and A. L. Joyner Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling Development, June 15, 2008; 135(12): 2093 - 2103. [Abstract] [Full Text] [PDF]

				X. Fan and C. G. Eberhart Medulloblastoma Stem Cells J. Clin. Oncol., June 10, 2008; 26(17): 2821 - 2827. [Abstract] [Full Text] [PDF]

				P. B. Dirks Brain Tumor Stem Cells: Bringing Order to the Chaos of Brain Cancer J. Clin. Oncol., June 10, 2008; 26(17): 2916 - 2924. [Abstract] [Full Text] [PDF]

				B. A. Hatton, E. H. Villavicencio, K. D. Tsuchiya, J. I. Pritchard, S. Ditzler, B. Pullar, S. Hansen, S. E. Knoblaugh, D. Lee, C. G. Eberhart, et al. The Smo/Smo Model: Hedgehog-Induced Medulloblastoma with 90% Incidence and Leptomeningeal Spread Cancer Res., March 15, 2008; 68(6): 1768 - 1776. [Abstract] [Full Text] [PDF]

				M. R. Grimmer and W. A. Weiss BMPs oppose Math1 in cerebellar development and in medulloblastoma Genes & Dev., March 15, 2008; 22(6): 693 - 699. [Full Text] [PDF]

				K. J. Briggs, I. M. Corcoran-Schwartz, W. Zhang, T. Harcke, W. L. Devereux, S. B. Baylin, C. G. Eberhart, and D. N. Watkins Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma Genes & Dev., March 15, 2008; 22(6): 770 - 785. [Abstract] [Full Text] [PDF]

				A-r. Jung, T. W. Kim, I. J. Rhyu, H. Kim, Y. D. Lee, S. Vinsant, R. W. Oppenheim, and W. Sun Misplacement of Purkinje Cells during Postnatal Development in Bax Knock-Out Mice: A Novel Role for Programmed Cell Death in the Nervous System? J. Neurosci., March 12, 2008; 28(11): 2941 - 2948. [Abstract] [Full Text] [PDF]

				R. V. Sillitoe and M. W. Vogel Desire, Disease, and the Origins of the Dopaminergic System Schizophr Bull, March 1, 2008; 34(2): 212 - 219. [Abstract] [Full Text] [PDF]

				D. Hambardzumyan, O. J. Becher, M. K. Rosenblum, P. P. Pandolfi, K. Manova-Todorova, and E. C. Holland PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo Genes & Dev., February 15, 2008; 22(4): 436 - 448. [Abstract] [Full Text] [PDF]

				B. Carletti and F. Rossi Neurogenesis in the Cerebellum Neuroscientist, February 1, 2008; 14(1): 91 - 100. [Abstract] [PDF]

				F. Balordi and G. Fishell Mosaic Removal of Hedgehog Signaling in the Adult SVZ Reveals That the Residual Wild-Type Stem Cells Have a Limited Capacity for Self-Renewal J. Neurosci., December 26, 2007; 27(52): 14248 - 14259. [Abstract] [Full Text] [PDF]

				R. Alvarez-Rodriguez, M. Barzi, J. Berenguer, and S. Pons Bone Morphogenetic Protein 2 Opposes Shh-mediated Proliferation in Cerebellar Granule Cells through a TIEG-1-based Regulation of Nmyc J. Biol. Chem., December 21, 2007; 282(51): 37170 - 37180. [Abstract] [Full Text] [PDF]

				J.-S. Yun, J. M. Rust, T. Ishimaru, and E. Diaz A Novel Role of the Mad Family Member Mad3 in Cerebellar Granule Neuron Precursor Proliferation Mol. Cell. Biol., December 1, 2007; 27(23): 8178 - 8189. [Abstract] [Full Text] [PDF]

				E. E. Bar, A. Chaudhry, A. Lin, X. Fan, K. Schreck, W. Matsui, S. Piccirillo, A. L. Vescovi, F. DiMeco, A. Olivi, et al. Cyclopamine-Mediated Hedgehog Pathway Inhibition Depletes Stem-Like Cancer Cells in Glioblastoma Stem Cells, October 1, 2007; 25(10): 2524 - 2533. [Abstract] [Full Text] [PDF]

				V. V. Chizhikov, J. Davenport, Q. Zhang, E. K. Shih, O. A. Cabello, J. L. Fuchs, B. K. Yoder, and K. J. Millen Cilia Proteins Control Cerebellar Morphogenesis by Promoting Expansion of the Granule Progenitor Pool J. Neurosci., September 5, 2007; 27(36): 9780 - 9789. [Abstract] [Full Text] [PDF]

				E. Salsano, L. Croci, E. Maderna, L. Lupo, B. Pollo, M. T. Giordana, G. G. Consalez, and G. Finocchiaro Expression of the neurogenic basic helix-loop-helix transcription factor NEUROG1 identifies a subgroup of medulloblastomas not expressing ATOH1 Neuro-oncol, July 1, 2007; 9(3): 298 - 307. [Abstract] [Full Text] [PDF]

				S. Farioli-Vecchioli, M. Tanori, L. Micheli, M. Mancuso, L. Leonardi, A. Saran, M. T. Ciotti, E. Ferretti, A. Gulino, S. Pazzaglia, et al. Inhibition of medulloblastoma tumorigenesis by the antiproliferative and pro-differentiative gene PC3 FASEB J, July 1, 2007; 21(9): 2215 - 2225. [Abstract] [Full Text] [PDF]

				S. Deng, A. Hirschberg, T. Worzfeld, J. Y. Penachioni, A. Korostylev, J. M. Swiercz, P. Vodrazka, O. Mauti, E. T. Stoeckli, L. Tamagnone, et al. Plexin-B2, But Not Plexin-B1, Critically Modulates Neuronal Migration and Patterning of the Developing Nervous System In Vivo J. Neurosci., June 6, 2007; 27(23): 6333 - 6347. [Abstract] [Full Text] [PDF]

				T. D. McCall, C. A. Pedone, and D. W. Fults Apoptosis Suppression by Somatic Cell Transfer of Bcl-2 Promotes Sonic Hedgehog-Dependent Medulloblastoma Formation in Mice Cancer Res., June 1, 2007; 67(11): 5179 - 5185. [Abstract] [Full Text] [PDF]

				F. Balordi and G. Fishell Hedgehog Signaling in the Subventricular Zone Is Required for Both the Maintenance of Stem Cells and the Migration of Newborn Neurons J. Neurosci., May 30, 2007; 27(22): 5936 - 5947. [Abstract] [Full Text] [PDF]

				C. Vaillant, O. Michos, S. Orolicki, F. Brellier, S. Taieb, E. Moreno, H. Te, R. Zeller, and D. Monard Protease nexin 1 and its receptor LRP modulate SHH signalling during cerebellar development Development, May 1, 2007; 134(9): 1745 - 1754. [Abstract] [Full Text] [PDF]

				R. H. Friedel, G. Kerjan, H. Rayburn, U. Schuller, C. Sotelo, M. Tessier-Lavigne, and A. Chedotal Plexin-B2 Controls the Development of Cerebellar Granule Cells J. Neurosci., April 4, 2007; 27(14): 3921 - 3932. [Abstract] [Full Text] [PDF]

				B. Stecca, C. Mas, V. Clement, M. Zbinden, R. Correa, V. Piguet, F. Beermann, and A. Ruiz i Altaba Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways PNAS, April 3, 2007; 104(14): 5895 - 5900. [Abstract] [Full Text] [PDF]

				W. A. Alcaraz, D. A. Gold, E. Raponi, P. M. Gent, D. Concepcion, and B. A. Hamilton Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation PNAS, December 19, 2006; 103(51): 19424 - 19429. [Abstract] [Full Text] [PDF]

				B. A. Hatton, P. S. Knoepfler, A. M. Kenney, D. H. Rowitch, I. M. de Alboran, J. M. Olson, and R. N. Eisenman N-myc Is an Essential Downstream Effector of Shh Signaling during both Normal and Neoplastic Cerebellar Growth. Cancer Res., September 1, 2006; 66(17): 8655 - 8661. [Abstract] [Full Text] [PDF]

				J. D. Corrales, S. Blaess, E. M. Mahoney, and A. L. Joyner The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation Development, May 1, 2006; 133(9): 1811 - 1821. [Abstract] [Full Text] [PDF]

				S. R. Browd, A. M. Kenney, O. N. Gottfried, J. W. Yoon, D. Walterhouse, C. A. Pedone, and D. W. Fults N-myc Can Substitute for Insulin-Like Growth Factor Signaling in a Mouse Model of Sonic Hedgehog-Induced Medulloblastoma. Cancer Res., March 1, 2006; 66(5): 2666 - 2672. [Abstract] [Full Text] [PDF]

				J. Cayuso, F. Ulloa, B. Cox, J. Briscoe, and E. Marti The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity Development, February 1, 2006; 133(3): 517 - 528. [Abstract] [Full Text] [PDF]

				R. J. Roper, L. L. Baxter, N. G. Saran, D. K. Klinedinst, P. A. Beachy, and R. H. Reeves Defective cerebellar response to mitogenic Hedgehog signaling in Down's syndrome mice PNAS, January 31, 2006; 103(5): 1452 - 1456. [Abstract] [Full Text] [PDF]