Pathogenesis of cleft palate in TGF-beta3 knockout mice

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Brunet, C. L., Sharpe, P. M. and Ferguson, M. W. J (1995). Inhibition of TGF-3 (but not TGF- 1 or TGF-2) activity prevents normal mouse embryonic palate fusion. Int. J. Dev. Biol 39, 345-355.[Medline]

Carette, M. J. M. and Ferguson, M. W. J (1992). The fate of medial edge epithelial cells during palatal fusion in vitro : an analysis by DiI labelling and confocal microscopy. Development 114, 379-388.[Abstract]

Curtis, A. S. and Buultjens, T. E (1973). Cell adhesion and locomotion. CIBA Found. Symp 14, 171-186.[Medline]

Ellis, I. R. and Schor, S. L (1998). Differential motogenic and biosynthetic response of fetal and adult skin fibroblasts to TGF-isoforms. Cytokine 10, 281-289.[Medline]

Ferguson, M. W. J., Honig, L. S. and Slavkin, H. C (1984). Differentiation of cultured palatal shelves from alligator, chick, and mouse embryos. Anat. Rec 209, 231-249.[Medline]

Ferguson, M. W. J (1988). Palate development. Development 103, 41-60.

Ferguson, M. W. J (1994). Craniofacial malformations: towards a molecular understanding. Nature Genet 6, 348-356.[Medline]

Fitchett, J. E. and Hay, E. D (1989). Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse. Dev. Biol 131, 455-474.[Medline]

Fitzpatrick, D. R., Denhez, F., Kondaiah, P. and Akhurst, R. J (1990). Differential expression of TGF-isoforms in murine palatogenesis. Development 109, 585-595.[Abstract]

Gedron-Maguire, M., Mallo, M., Zhang, M. and Gridley, T (1993). Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell 75, 1317-1331.[Medline]

Greene, M. R. and Pratt, R. M (1977). Inhibition by diazo-oxo-norleucine (DON) of rat palatal glycoprotein synthesis and epithelial cell adhesion in vitro. Exp. Cell Res 105, 27-37.[Medline]

Griffith, C. M. and Hay, E. D (1992). Epithelial-mesenchymal transformation during palatal fusion: carboxyfluorescein traces cells at light and electron microscopic levels. Development 116, 1087-1099.[Abstract]

Gumbiner, B. M (1996). Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell 84, 345-357.[Medline]

Imamura, T., Takase, M., Nishihara, A., Oede, E., Hanai., Kawabata, M. and Miyazono, K (1998). Smad6 inhibits signalling by the TGF-superfamily. Nature 389, 622-626.

Iozzo, R. V., Pillarisetti, J., Sharma, B., Murdoch, A. D., Danielson, K. G., Uitto, J. and Mauviel, A (1997). Structural and functional characterization of the human perlecan gene promoter. J. Biol. Chem 272, 5219-5228.[Abstract/Free Full Text]

Kaartinen, V., Volcken, J. W., Shuler, C., Warburton, D., Bu, D., Heisterkamp, N. and Groffen, J (1995). Abnormal lung development andcleft palate in mice lacking TGF-3 indicates defects of epithelial-mesenchymal interaction. Nature Genet 11, 415-421.[Medline]

Kingsley, D. M (1994). The TGF-superfamily: new members, new receptors and new genetic tests of function in different organisms. Genes. Dev 8, 133-146.[Free Full Text]

Kulkarni, A. B., Huh, C., Becker, D., Geiser, A., Lyght, M., Flanders, K. C., Roberts, A. B., Sporn, M. B., Ward, J. M. and Karlsson, S (1993). Transforming growth factor-1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA 90, 770-774.[Abstract/Free Full Text]

Kurihara, Y., Kurihara, H., Suzuki, H., Kodama, T., Maemura, K., Nagai, R., Oda, H., Kuwaki, T., Cao, W. H., Kamada, N., Jishage, K., Ouchi, Y., Azuma, S., Toyoda, Y., Ishikawa, T., Kumada, M. and Yazaki, Y (1994). Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature 368, 703-710.[Medline]

Laird, P. W. Zijderveld, A., Linders, K., Rudnicki, M. A., Jaenisch, R. and Berns, A (1991). Simplified mammalian DNA isolation procedure. Nucl. Acids Res 19, 4293-.[Free Full Text]

Letterio, J. J., Geiser, A. G., Kulkarni, A. B., Roche, N. S., Sporn, M. B. and Roberts, A. B (1994). Maternal rescue of transforming growth factor-1 null mice. Science 264, 1936-1938.[Abstract/Free Full Text]

Lohnes, D., Kastner, P., Dierich, A., Mark, M., LeMeur, M. and Chambon, P (1993). Function of retinoic acid receptors gamma in the mouse. Cell 73, 643-658.[Medline]

Lohnes, D., Mark, M., Mendelsohn, C., Dolle, P., Dierich, A., Gorry, P., Gansmuller, A. and Chambon, P (1994). Function of the retinoic acid receptors (RARs) during development, (I) Craniofacial and skeletal abnormalities in RAR double mutants. Development 120, 2723-2748.[Abstract]

Martin, J. F., Bradley, A. and Olsen, E. N (1995). The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages. Genes Dev 9, 1237-1249.[Abstract/Free Full Text]

Matzuk, M. M., Kumar, T. R., Vassalli, A., Bickenbach, J. R., Roop, D. R., Jaenisch, R. and Bradley, A (1995). Functional analysis of activins during mammalian development. Nature 374, 354-356.[Medline]

Matzuk, M. M., Kumar, T. R. and Bradley, A (1995). Different phenotypes for mice deficient in either activins or activin receptor type II. Nature 374, 356-360.[Medline]

Matzuk, M. M., Lu, N., Vogel, H., Sellheyer, K., Roop, D. R. and Bradley, A (1995). Multiple defects and perinatal death in mice deficient in follistatin. Nature 374, 360-363.[Medline]

Miettinen, P. J., Chin, J. R., Shum, L., Slavkin, H. C., Shuler, C. F., Derynck, R. and Werb, Z (1999). Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure. Nature Genet 22, 69-73.[Medline]

Mo, R. Freer, A. M., Zinyk, D. L., Crackower, M. A., Michaud, J., Heng, H. H., Chik, K. W., Shi, X. M., Tsui, L. C., Cheng, S. H., Joyner, A. L. and Hui, C (1997). Specific and redundant function of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development 124, 113-123.[Abstract]

Nakao, A., Afrakhte, M., Moren, A., Nakajima, T., Christian, J. L., Heuchel, R., Itoh, S., Kawabata, M., Heldin, N. E., Heldin, C. H. and ten Dijke, P (1997). Identification of smad7, a TGF-inducible antagonist of TGF- signalling. Nature 389, 631-635.[Medline]

Nobes, C. D. and Hall, A (1995). Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexs associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62.[Medline]

Orioli, D., Henkemeyer, M., Lemke, G., Klein, R. and Pawson, T (1996). Sek4 and nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J 15, 6035-6049.[Medline]

Pelton, R. W., Hogan, B. L., M., Miller, D. A. and Moses, H. L (1990). Differential expression of genes encoding TGF-1, 2 and3 during murine palate formation. Dev. Biol 141, 456-460.[Medline]

Peters, H., Neubuser, A. and Balling, R (1997). The role of Pax9 during mouse development. Dev. Biol 186, 333-.

Proetzel, G., Pawlowski, S. A., Wiles, M. V., Yin, M., Boivin, G. P., Howles, P. N., Ding, J., Ferguson, M. W. J. and Doetschman, T (1995). Transformating growth factor-3 is required for secondary palate fusion. Nature Genet 11, 409-414.[Medline]

Ramsdell, A. F. and Markwald R. R (1997). Induction of endocardial cushion tissue in the avian heart is regulated, in part, by TGF beta-3-mediated autocrine signalling. Dev. Biol 188, 64-74.[Medline]

Rijli, F. M., Mark, M., Lakkaraju, S., Dierich, A., Dolle, P. and Chambon,P (1993). A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene. Cell 75, 1333-1349.[Medline]

Sanford, L. P., Ormsby I., Groot A. C. G., Sarinola H., Friedman R., Boivin, G. P., Cardell E. L. and Doetschman T (1997). TGF-2 knockout mice have multiple developmental defects that are non-overlapping with other TGF- knockout phenotype. Development 124, 2659-2670.[Abstract]

Satokata, I. and Maas, R (1994). Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nature Genet 6, 348-355.

Schupback, P. M. and Schroeder, H. E (1986). Fate of unfused medial edge epithelia in rat fetuses with experimentally induced cleft palate: 1. from 16.3 to 17.7 days of gestation. J. Craniofacial. Genet 2, 293-318.

Shah, M., Foreman, D. M. and Ferguson, M. W. J (1995). Neutralisation of TGF-1 and TGF- 2 or exogenous addition of TGF-3 to cutaneous rat wounds reduces scarring. J. Cell Sci 108, 985-1002.[Abstract]

Shuler, C. F., Guo, Y., Majumder, A. and Luo, R (1991). Molecular and morphologic changes during the epithelial-mesenchymal transformation of palatal shelf medial edge epithelium in vitro. Int. J. Dev. Biol 35, 463-472.[Medline]

Shuler, C. F., Halpern, D. E., Guo, Y. and Sank, A. C (1992). Medial edge epithelium fate traced by cell lineage analysis during epithelial-mesenchymal transformation in vivo. Dev. Biol 154, 318-330.[Medline]

Shull, M. M., Ormsby, I., Kier, A. B., Pawlowski, S., Diebold, R. J., Yin,M., Allen, R., Sidman, C., Proetzel, G., Calvin, D., Annunziata, N. and Doetschman, T (1992). Targeted disruption of the mouse transforming growth factor-1 gene results in multifocal inflammatory disease. Nature 359, 693-699.[Medline]

Sun, D., Vandergurg, C. R., Odierna, G. S. and Hay, E (1998). TGF-3 promotes transformation of chicken palate medial edge epithelium to mesenchyme in vitro. Development 125, 95-105.[Abstract]

Takagi, T., Moribe, H., Kondoh, H. and Higashi, Y (1998). deltaEF1, a zinc finger and homeodomein transcription factor, is required for skelton patterning in multi lineages. Development 125, 21-31.[Abstract]

Takihara, Y., Tomotsune, D., Shirai, M., Katoh, F. Y., Nishii, K., Motaleb, M. A., Nomura, M., Tsuchiya, R., Fujita, Y., Shibata, Y., Higashinakagawa, T. and Shimada, K (1997). Targeted distruption of the mouse homolog of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects. Development 124, 3673-3682.[Abstract]

Tissier-Seta, J-P., Mucchielli, M-L., Mark, M., Mattei, M-G., Goridis, C. and Brunet, J-F (1995). Barx1, a new mouse homeodomain transcription factor expressed in cranio-facial ectomesenchyme and the stomach. Mech. Dev 51, 3-15.[Medline]

Waterman, R. E., Ross, L. M. and Meller, S. M (1973). Alternations in the epithelial surface of A/Jax mouse palatal shelves prior to and during of palatal fusion: a scanning electron microscopic study. Anat. Rec 176, 361-376.[Medline]

Winograd, J., Reilly, M. P., Roe, R., Lutz, J., Laughner, E., Xu, X., Hu, L., Asakura, T., vander Kolk, C., Strandberg, J. D. and Semenza, G. L (1997). Perinatal lethality and multiple craniofacial malformations in MSX2 transgenic mice. Human Mol. Genet 6, 369-379.[Abstract/Free Full Text]

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				L.-q. Gan, Y.-x. Fu, X. Liu, L. Qiu, S.-d. Wu, X.-f. Tian, Y. Liu, and G.-h. Wei Transforming growth factor-{beta}3 expression up-regulates on cleft palates induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice Toxicology and Industrial Health, August 1, 2009; 25(7): 473 - 478. [Abstract] [PDF]

				R. J. Richardson, J. Dixon, R. Jiang, and M. J. Dixon Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence Hum. Mol. Genet., July 15, 2009; 18(14): 2632 - 2642. [Abstract] [Full Text] [PDF]

				W. Yu, L.-B. Ruest, and K. K. H. Svoboda Regulation of Epithelial-Mesenchymal Transition in Palatal Fusion Experimental Biology and Medicine, May 1, 2009; 234(5): 483 - 491. [Abstract] [Full Text] [PDF]

				L. Meng, Z. Bian, R. Torensma, and J.W. Von den Hoff Biological Mechanisms in Palatogenesis and Cleft Palate Journal of Dental Research, January 1, 2009; 88(1): 22 - 33. [Abstract] [Full Text] [PDF]

				F. He, W. Xiong, X. Yu, R. Espinoza-Lewis, C. Liu, S. Gu, M. Nishita, K. Suzuki, G. Yamada, Y. Minami, et al. Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development Development, December 1, 2008; 135(23): 3871 - 3879. [Abstract] [Full Text] [PDF]

				D. E. Clouthier, J. Gray, and K. B. Artinger Micromanaging Palate Development Speech Science and Orofacial Disorders, October 1, 2008; 18(2): 62 - 72. [Abstract] [Full Text] [PDF]

				D. M. Gupta, N. J. Panetta, M. T. Longaker, and H. P. Lorenz Tissue Engineering Applications for Cleft Palate Reconstruction Speech Science and Orofacial Disorders, October 1, 2008; 18(2): 73 - 86. [Abstract] [Full Text] [PDF]

				A. Nawshad, D. Medici, C.-C. Liu, and E. D. Hay TGFbeta3 inhibits E-cadherin gene expression in palate medial-edge epithelial cells through a Smad2-Smad4-LEF1 transcription complex J. Cell Sci., May 1, 2007; 120(9): 1646 - 1653. [Abstract] [Full Text] [PDF]

				S. A. Murray, K. F. Oram, and T. Gridley Multiple functions of Snail family genes during palate development in mice Development, May 1, 2007; 134(9): 1789 - 1797. [Abstract] [Full Text] [PDF]

				V. C Dhulipala, W. V Welshons, and C. S Reddy Cell cycle proteins in normal and chemically induced abnormal secondary palate development: a review Human and Experimental Toxicology, November 1, 2006; 25(11): 675 - 682. [Abstract] [PDF]

				S. McDougall, J. Dallon, J. Sherratt, and P. Maini Fibroblast migration and collagen deposition during dermal wound healing: mathematical modelling and clinical implications Phil Trans R Soc A, June 15, 2006; 364(1843): 1385 - 1405. [Abstract] [Full Text] [PDF]

				D. A. Gorvy, S. E. Herrick, M. Shah, and M. W.J. Ferguson Experimental Manipulation of Transforming Growth Factor-{beta} Isoforms Significantly Affects Adhesion Formation in a Murine Surgical Model Am. J. Pathol., October 1, 2005; 167(4): 1005 - 1019. [Abstract] [Full Text] [PDF]

				P. Kang and K.K.H. Svoboda Epithelial-Mesenchymal Transformation during Craniofacial Development Journal of Dental Research, August 1, 2005; 84(8): 678 - 690. [Abstract] [Full Text] [PDF]

				P. Pungchanchaikul, M. Gelbier, P. Ferretti, and A. Bloch-Zupan Gene Expression during Palate Fusion in vivo and in vitro Journal of Dental Research, June 1, 2005; 84(6): 526 - 531. [Abstract] [Full Text] [PDF]

				T. L. Thomae, E. A. Stevens, and C. A. Bradfield Transforming Growth Factor-{beta}3 Restores Fusion in Palatal Shelves Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin J. Biol. Chem., April 1, 2005; 280(13): 12742 - 12746. [Abstract] [Full Text] [PDF]

				S.S. Prime, M. Pring, M. Davies, and I.C. Paterson TGF-{beta} SIGNAL TRANSDUCTION IN ORO-FACIAL HEALTH AND NON-MALIGNANT DISEASE (PART I) Critical Reviews in Oral Biology & Medicine, November 1, 2004; 15(6): 324 - 336. [Abstract] [Full Text] [PDF]

				Y. Sasaki, S. Tanaka, T. Hamachi, and Y. Taya Deficient Cell Proliferation in Palatal Shelf Mesenchyme of CL/Fr Mouse Embryos Journal of Dental Research, October 1, 2004; 83(10): 797 - 801. [Abstract] [Full Text] [PDF]

				T. L. Thomae, E. Glover, and C. A. Bradfield A Maternal Ahr Null Genotype Sensitizes Embryos to Chemical Teratogenesis J. Biol. Chem., July 16, 2004; 279(29): 30189 - 30194. [Abstract] [Full Text] [PDF]

				P. Martin and S. M. Parkhurst Parallels between tissue repair and embryo morphogenesis Development, July 1, 2004; 131(13): 3021 - 3034. [Abstract] [Full Text] [PDF]

				Y. Lan, C. E. Ovitt, E.-S. Cho, K. M. Maltby, Q. Wang, and R. Jiang Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis Development, July 1, 2004; 131(13): 3207 - 3216. [Abstract] [Full Text] [PDF]

				P. Stanier and G. E. Moore Genetics of cleft lip and palate: syndromic genes contribute to the incidence of non-syndromic clefts Hum. Mol. Genet., April 1, 2004; 13(suppl_1): R73 - R81. [Abstract] [Full Text] [PDF]

				R. Cuervo and L. Covarrubias Death is the major fate of medial edge epithelial cells and the cause of basal lamina degradation during palatogenesis Development, January 1, 2004; 131(1): 15 - 24. [Abstract] [Full Text] [PDF]

				Y. Ito, J. Y. Yeo, A. Chytil, J. Han, P. Bringas Jr, A. Nakajima, C. F. Shuler, H. L. Moses, and Y. Chai Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects Development, November 1, 2003; 130(21): 5269 - 5280. [Abstract] [Full Text] [PDF]

				M. K. Bunger, S. M. Moran, E. Glover, T. L. Thomae, G. P. Lahvis, B. C. Lin, and C. A. Bradfield Resistance to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Toxicity and Abnormal Liver Development in Mice Carrying a Mutation in the Nuclear Localization Sequence of the Aryl Hydrocarbon Receptor J. Biol. Chem., May 9, 2003; 278(20): 17767 - 17774. [Abstract] [Full Text] [PDF]

				H. Chang, C. W. Brown, and M. M. Matzuk Genetic Analysis of the Mammalian Transforming Growth Factor-{beta} Superfamily Endocr. Rev., December 1, 2002; 23(6): 787 - 823. [Abstract] [Full Text] [PDF]

				K. Kohama, K. Nonaka, R. Hosokawa, L. Shum, and M. Ohishi TGF-beta-3 Promotes Scarless Repair of Cleft Lip in Mouse Fetuses Journal of Dental Research, October 1, 2002; 81(10): 688 - 694. [Abstract] [Full Text] [PDF]

				Z. Zhang, Y. Song, X. Zhao, X. Zhang, C. Fermin, and Y. Chen Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis Development, September 1, 2002; 129(17): 4135 - 4146. [Abstract] [Full Text] [PDF]

				L. Blavier, A. Lazaryev, J. Groffen, N. Heisterkamp, Y. A. DeClerck, and V. Kaartinen TGF-{beta}3-induced Palatogenesis Requires Matrix Metalloproteinases Mol. Biol. Cell, May 1, 2001; 12(5): 1457 - 1466. [Abstract] [Full Text]

				V. M. Riccardi Of Mass and Men: Neurofibromas and Histogenesis Arch Dermatol, October 1, 2000; 136(10): 1257 - 1258. [Full Text] [PDF]

				E. Martin-Blanco, J. C. Pastor-Pareja, and A. Garcia-Bellido From the Cover: JNK and decapentaplegic signaling control adhesiveness and cytoskeleton dynamics during thorax closure in Drosophila PNAS, July 5, 2000; 97(14): 7888 - 7893. [Abstract] [Full Text] [PDF]