Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain

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Blackwood, E. M. and Kadonaga, J. T (1998). Going the distance: a current view of enhancer action. Science 281, 60-63.[Abstract/Free Full Text]

Burns, J. C., Friedmann, T., Driever, W., Burrascano, M. and Yee, J.-K (1993). Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc. Natl. Acad. Sci. USA 90, 8033-8037.[Abstract/Free Full Text]

Castillo, S. O., Baffi, J. S., Palkovits, M., Goldstein, D. S., Kopin, I. J., Witta, J., Magnuson, M. A. and Nikodem, V. M (1998). DA biosynthesis is selectively abolished in substantia nigra/ventral tegmental area but not in hypothalamic neurons in mice with targeted disruption of the Nurr1 gene. Mol. Cell.Neurosci 11, 36-46.[Medline]

Castillo, S. O., Xiao, Q., Kostrouch, Z., Dozin, B. and Nikodem, V. M (1998). A divergent role of COOH-terminal domains in Nurr1 and Nur77 transactivation. Gene Expression 7, 1-12.[Medline]

Castillo, S. O., Xiao, Q., Lyu, M. S., Kozak, C. A. and Nikodem, V. M (1997). Organization, sequence, chromosomal localization, and promoter identification of the mouse orphan nuclear receptor Nurr1 gene. Genomics 41, 250-257.[Medline]

Crossley, P. H., Martinez, S. and Martin, G. R (1996). Midbrain development induced by FGF8 in the chick embryo. Nature 380, 66-68.[Medline]

Ericson, J., Morton, S., Kawakami, A., Roelink, H., Jessell T.,M (1996). Two critical periods of sonic hedgehog signaling required for the specification of motor neuron identity. Cell 87, 661-673.[Medline]

Ericson, J., Muhr, J., Placzek, M., Lints, T., Jessell,T. M. and Edlund, T (1995). Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube. Cell 81, 747-756.[Medline]

Forman, B. M., Umesono, K., Chen, J. and Evans, R. M (1995). Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell 81, 541-550.[Medline]

Gage, F. H., Ray, J. and Fisher, L. J (1995). Isolation, characterization, and use of stem cells from the CNS. Annu. Rev.Neurosci 18, 159-192.[Medline]

Gritti, A., Parati, E. A., Cova, L., Frolichsthal, P., Galli, R., Wanke, E., Faravelli, L., Morassutti, D. J., Roisen, F., Nickel, D. D. and Vescovi, A. L (1996). Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J. Neurosci 16, 1091-1100.[Abstract/Free Full Text]

Hammerschmidt, M., Brook, A. and McMahon, A. P (1997). The world according to hedgehog. Trends Genet 13, 14-21.[Medline]

Hoshimaru, M., Ray, J., Sah, D. W. Y. and Gage, F. H (1996). Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene. Proc. Natl. Acad. Sci.USA 93, 1518-1523.[Abstract/Free Full Text]

Hui, C.-C., Slusarski, D., Platt, K. A., Holmgren, R. and Joyner, A. L (1994). Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli1, Gli-2, and Gli-3, in ectoderm-and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev. Biol 162, 402-413.[Medline]

Hynes, M., Porter, J. A., Chiang, C., Chang, D., Tessier-Lavigne, M., Beachy, P. A. and Rosenthal, A (1995). Induction of midbrain dopaminergic neurons by Sonic hedgehog. Neuron 15, 35-44.[Medline]

Hynes, M., Stone, D. M., Dowd, M., Pitts-Meek, S., Goddard, A., Gurney, A. and Rosenthal, A (1997). Control of cell pattern in the neural tube bythe zinc finger transcription factor and oncogene Gli-1. Neuron 19, 15-26.[Medline]

Johansson, C. B., Momma, S., Clarke, D. L., Risling, M., Lendahl, U. and Frisen, J (1999). Identification of a neural stem cell in the adult mammalian central nervous system. Cell 96, 25-34.[Medline]

Johe, K. K., Hazel, T. G., Muller, T., Dugich-Djordjevic, M. M. and McKay, R. D. G (1996). Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev 10, 3129-3140.[Abstract/Free Full Text]

Law, S. W., Conneely, O. M., DeMayo, F. J., O'Malley, B. W (1992). Identification of a new brain-specific transcription factor, NURR1. Mol. Endocrinol 6, 2192-2135.

McEwen, D. G. and Ornitz, D. M (1997). Determination of fibroblast growth factor receptor expression in mouse, rat and human samples using a single primer pair. BioTechniques 22, 1068-1069.[Medline]

McKay, R (1997). Stem cells in the central nervous system. Science 276, 66-71.[Abstract/Free Full Text]

Miller, A. D. and Rosman, G. J (1989). Improved retroviral vectors for gene transfer and expression. BioTechniques 7, 980-989.[Medline]

Morrison, S. J., Shah, N. M. and Anderson, D. J (1997). Regulatory mechanisms in stem cell biology. Cell 88, 287-298.[Medline]

Naviaux, R. K., Costanzi, E., Haas, M. and Verma, I. M (1996). The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses. J. Virol 70, 5701-5705.[Abstract/Free Full Text]

Okayama, H., Kawaichi, M., Brownstein, M., Lee, F., Yokota, T. and Arai, K (1987). High-efficiency cloning of full-length cDNA: Construction and screening of cDNA expression libraries for mammalian cells. Methods Enzymol 154, 3-28.[Medline]

Ornitz, D. M., Xu, J., Colvin, J. S., McEwen, D. G., MacArthur, C. A., Coulier, F., Gao, G. and Goldfarb, M (1996). Receptor specificity of the fibroblast growth factor family. J. Biol. Chem 271, 15292-15297.[Abstract/Free Full Text]

Palmer, T. D., Takahashi, J. and Gage, F. H (1997). The adult rat hippocampus contains primordial neural stem cells. Mol.Cell. Neurosci 8, 389-404.[Medline]

Perlmann, T. and Jansson, L (1995). A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev 9, 769-782.[Abstract/Free Full Text]

Placzek, M., Yamada, T., Tessier-Lavigne, M., Jessell, T. and Dodd, J (1991). Control of dorsoventral pattern in vertebrate neural development: induction and polarizing properties of the floor plate. Development 2, 105-122.

Ray, J., Peterson, D. A., Schinstine, M. and Gage, F. H (1993). Proliferation, differentiation, and long-term culture of primary hippocampal neurons. Proc. Natl. Acad. Sci. USA 90, 3602-3606.[Abstract/Free Full Text]

Saucedo-Cardenas, O., Quintana-Hau, J. D., Le, W.-D., Smidt, M. P., Cox, J. J., De Mayo, F., Burbach, J. P. H. and Conneely, O. M (1998). Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc. Natl. Acad. Sci. USA 95, 4013-4018.[Abstract/Free Full Text]

Semina, E. V., Ferrell, R. E., Mintz-Hittner, H. A., Bitoun, P., Alward, W. L. M., Reiter, R. S., Funkhauser, C., Daack-Hirsch, S. and Murray, J. C (1998). A novel homeobox gene PITX3 is mutated in families with autosomal-dominant cataracts and ASMD. Nature Genet 19, 167-170.[Medline]

Semina, E. V., Reiter, R. S. and Murray, J. C (1997). Isolation of a new homeobox gene belonging to the Pitx/Rieg family: expression during lens development and mapping to the aphakia region on mouse chromosome 19. Human Mol. Genet 6, 2109-2116.[Abstract/Free Full Text]

Smidt, M. P., van Schaick, H. S. A., Lanctot, C., Tremblay, J. J., Cox, J. J., van der Kleij, A. A. M., Wolterink, G., Drouin, J. and Burbach, J. P. H (1997). A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons. Proc. Natl. Acad. Sci. USA 94, 13305-13310.[Abstract/Free Full Text]

Stemple, D. L. and Mahanthappa, N. K (1997). Neural stem cells are blasting off. Neuron 18, 1-4.[Medline]

Suhonen, J. O., Peterson, D. A., Ray, J. and Gage, F. H (1996). Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature 383, 624-627.[Medline]

Takahashi, J., Palmer, T. D. and Gage, F. H (1999). Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures. J. Neurobiol 38, 65-81.[Medline]

Tinti, C., Yang, C., Seo, H., Conti, B., Kim, C., Joh, T. H. and Kim, K.-S (1997). Structure/function relationship of the cAMP response element in tyrosine hydroxylase gene transcription. J.Biol. Chem 272, 19158-19164.[Abstract/Free Full Text]

Tiveron, M. C., Hirsch, M. R. and Brunet, J. F (1996). The expression pattern of the transcription factor Phox2a delineates synaptic pathways of the autonomic nervous system. J. Neurosci 16, 7649-7660.[Abstract/Free Full Text]

Valarche, I., Tissier-Seta, J. P., Hirsch, M. R., Martinez, S., Goridis, C. and Brunet, J. F (1993). The mouse homeodomain protein Phox2 regulates NCAM promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype. Development 119, 881-896.[Abstract]

Wechsler-Reya R. J., Scott, M. P (1999). Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. Neuron 22, 103-114.[Medline]

Wilson, T. E., T. E., Fahrner, T. J., Milbrandt, J (1993). The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction. Mol. Cell Biol 13, 5794-5804.[Abstract/Free Full Text]

Wilson, T. E., T. E., Fahrner, T. J., Johnston, M., Milbrandt, J (1991). Identification of the DNA binding site for NGFI-B by genetic selection in yeast. Science 252, 1297-1300.

Ye, W., Shimamura, K., Rubenstein, J. L. R., Hynes, M. A. and Rosenthal, A (1998). FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell 93, 755-766.[Medline]

Yokoi, H., Natsuyama, S., Iwai, M., Noda, Y., Mori, T., Mori, K. J., Fujita, K., Nakayama, H. and Fujita, J (1993). Non-radioisotopic quantitative RT-PCR to detect changes in mRNA levels during early mouse embryo development. Biochem. Biophys. Res. Commun 195, 769-775.[Medline]

Zetterstrom, R. H., Solomin, L., Jansson, L., Hoffer, B. J., Olson, L. and Perlmann, T (1997). Dopamine neuron agenesis in Nurr1-deficient mice. Science 276, 248-250.[Abstract/Free Full Text]

Zetterstrom, R. H., Solomin, L., Mitsiadis, T., Olson, L. and Perlmann, T (1996). Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1. Mol. Endocrinol 10, 1656-1666.[Abstract]

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				N. Prakash and W. Wurst Genetic networks controlling the development of midbrain dopaminergic neurons J. Physiol., September 1, 2006; 575(2): 403 - 410. [Abstract] [Full Text] [PDF]

				E. Roussa, M. Wiehle, N. Dunker, S. Becker-Katins, O. Oehlke, and K. Krieglstein Transforming Growth Factor {beta} Is Required for Differentiation of Mouse Mesencephalic Progenitors into Dopaminergic Neurons In Vitro and In Vivo: Ectopic Induction in Dorsal Mesencephalon Stem Cells, September 1, 2006; 24(9): 2120 - 2129. [Abstract] [Full Text] [PDF]

				S. Traver, M. Marien, E. Martin, E. C. Hirsch, and P. P. Michel The Phenotypic Differentiation of Locus Ceruleus Noradrenergic Neurons Mediated by Brain-Derived Neurotrophic Factor Is Enhanced by Corticotropin Releasing Factor through the Activation of a cAMP-Dependent Signaling Pathway Mol. Pharmacol., July 1, 2006; 70(1): 30 - 40. [Abstract] [Full Text] [PDF]

				C.-H. Park, J. S. Kang, J.-S. Kim, S. Chung, J.-Y. Koh, E.-H. Yoon, A. Y. Jo, M.-Y. Chang, H.-C. Koh, S. Hwang, et al. Differential actions of the proneural genes encoding Mash1 and neurogenins in Nurr1-induced dopamine neuron differentiation J. Cell Sci., June 1, 2006; 119(11): 2310 - 2320. [Abstract] [Full Text] [PDF]

				L. Pei, A. Castrillo, and P. Tontonoz Regulation of Macrophage Inflammatory Gene Expression by the Orphan Nuclear Receptor Nur77 Mol. Endocrinol., April 1, 2006; 20(4): 786 - 794. [Abstract] [Full Text] [PDF]

				J.-Y. Jeong, Z. Einhorn, S. Mercurio, S. Lee, B. Lau, M. Mione, S. W. Wilson, and S. Guo Neurogenin1 is a determinant of zebrafish basal forebrain dopaminergic neurons and is regulated by the conserved zinc finger protein Tof/Fezl PNAS, March 28, 2006; 103(13): 5143 - 5148. [Abstract] [Full Text] [PDF]

				D.-W. Kim, S. Chung, M. Hwang, A. Ferree, H.-C. Tsai, J.-J. Park, S. Chung, T. S. Nam, U. J. Kang, O. Isacson, et al. Stromal Cell-Derived Inducing Activity, Nurr1, and Signaling Molecules Synergistically Induce Dopaminergic Neurons from Mouse Embryonic Stem Cells Stem Cells, March 1, 2006; 24(3): 557 - 567. [Abstract] [Full Text] [PDF]

				C. Martinat, J.-J. Bacci, T. Leete, J. Kim, W. B. Vanti, A. H. Newman, J. H. Cha, U. Gether, H. Wang, and A. Abeliovich Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype PNAS, February 21, 2006; 103(8): 2874 - 2879. [Abstract] [Full Text] [PDF]

				K. Ohyama, P. Ellis, S. Kimura, and M. Placzek Directed differentiation of neural cells to hypothalamic dopaminergic neurons Development, December 1, 2005; 132(23): 5185 - 5197. [Abstract] [Full Text] [PDF]

				S. Z. Imam, J. Jankovic, S. F. Ali, J. T. Skinner, W. Xie, O. M. Conneely, and W.-D. Le Nitric oxide mediates increased susceptibility to dopaminergic damage in Nurr1 heterozygous mice FASEB J, September 1, 2005; 19(11): 1441 - 1450. [Abstract] [Full Text] [PDF]

				L. Pei, A. Castrillo, M. Chen, A. Hoffmann, and P. Tontonoz Induction of NR4A Orphan Nuclear Receptor Expression in Macrophages in Response to Inflammatory Stimuli J. Biol. Chem., August 12, 2005; 280(32): 29256 - 29262. [Abstract] [Full Text] [PDF]

				Y L Bao, K Tsuchida, B Liu, A Kurisaki, T Matsuzaki, and H Sugino Synergistic activity of activin A and basic fibroblast growth factor on tyrosine hydroxylase expression through Smad3 and ERK1/ERK2 MAPK signaling pathways J. Endocrinol., March 1, 2005; 184(3): 493 - 504. [Abstract] [Full Text] [PDF]

				T. Akagi, M. Mandai, S. Ooto, Y. Hirami, F. Osakada, R. Kageyama, N. Yoshimura, and M. Takahashi Otx2 Homeobox Gene Induces Photoreceptor-Specific Phenotypes in Cells Derived from Adult Iris and Ciliary Tissue Invest. Ophthalmol. Vis. Sci., December 1, 2004; 45(12): 4570 - 4575. [Abstract] [Full Text] [PDF]

				X. Zeng, J. Cai, J. Chen, Y. Luo, Z.-B. You, E. Fotter, Y. Wang, B. Harvey, T. Miura, C. Backman, et al. Dopaminergic Differentiation of Human Embryonic Stem Cells Stem Cells, November 1, 2004; 22(6): 925 - 940. [Abstract] [Full Text] [PDF]

				J. Lammi, J. Huppunen, and P. Aarnisalo Regulation of the Osteopontin Gene by the Orphan Nuclear Receptor NURR1 in Osteoblasts Mol. Endocrinol., June 1, 2004; 18(6): 1546 - 1557. [Abstract] [Full Text] [PDF]

				D. Galleguillos, A. Vecchiola, J. A. Fuentealba, V. Ojeda, K. Alvarez, A. Gomez, and M. E. Andres PIAS{gamma} Represses the Transcriptional Activation Induced by the Nuclear Receptor Nurr1 J. Biol. Chem., January 16, 2004; 279(3): 2005 - 2011. [Abstract] [Full Text] [PDF]

				B. Joseph, A. Wallen-Mackenzie, G. Benoit, T. Murata, E. Joodmardi, S. Okret, and T. Perlmann p57Kip2 cooperates with Nurr1 in developing dopamine cells PNAS, December 23, 2003; 100(26): 15619 - 15624. [Abstract] [Full Text] [PDF]

				K. D. S. A. Wansa, J. M. Harris, G. Yan, P. Ordentlich, and G. E. O. Muscat The AF-1 Domain of the Orphan Nuclear Receptor NOR-1 Mediates Trans-activation, Coactivator Recruitment, and Activation by the Purine Anti-metabolite 6-Mercaptopurine J. Biol. Chem., June 27, 2003; 278(27): 24776 - 24790. [Abstract] [Full Text] [PDF]

				P. Ordentlich, Y. Yan, S. Zhou, and R. A. Heyman Identification of the Antineoplastic Agent 6-Mercaptopurine as an Activator of the Orphan Nuclear Hormone Receptor Nurr1 J. Biol. Chem., June 27, 2003; 278(27): 24791 - 24799. [Abstract] [Full Text] [PDF]

				R. Dono Fibroblast growth factors as regulators of central nervous system development and function Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2003; 284(4): R867 - R881. [Abstract] [Full Text] [PDF]

				Y. Arsenijevic, N. Taverney, C. Kostic, M. Tekaya, F. Riva, L. Zografos, D. Schorderet, and F. Munier Non-neural Regions of the Adult Human Eye: A Potential Source of Neurons? Invest. Ophthalmol. Vis. Sci., February 1, 2003; 44(2): 799 - 807. [Abstract] [Full Text] [PDF]

				T. Suzuki, T. Yamakuni, M. Hagiwara, and H. Ichinose Identification of ATF-2 as a Transcriptional Regulator for the Tyrosine Hydroxylase Gene J. Biol. Chem., October 18, 2002; 277(43): 40768 - 40774. [Abstract] [Full Text] [PDF]

				P. Sacchetti, H. Dwornik, P. Formstecher, C. Rachez, and P. Lefebvre Requirements for Heterodimerization between the Orphan Nuclear Receptor Nurr1 and Retinoid X Receptors J. Biol. Chem., September 13, 2002; 277(38): 35088 - 35096. [Abstract] [Full Text] [PDF]

				K. D. S. A. Wansa, J. M. Harris, and G. E. O. Muscat The Activation Function-1 Domain of Nur77/NR4A1 Mediates Trans-activation, Cell Specificity, and Coactivator Recruitment J. Biol. Chem., August 30, 2002; 277(36): 33001 - 33011. [Abstract] [Full Text] [PDF]