Loss of p27Kip1 function results in increased proliferative capacity of oligodendrocyte progenitors but unaltered timing of differentiation

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Barres, B., Lazar, M. and Raff, M (1994). A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing of oligodendrocyte development. Development 120, 1097-1108.[Abstract]

Barres, B. A. and Raff, M. C (1993). Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons. Nature 361, 258-260.[Medline]

Blaschuck, K. L. and ffrench-Constant, C (1998). Notch is tops in the developing brain. Curr. Biol 8, 334-.

Calver, A. R., Hall, A. C., Yu W. P, Walsh F. S., Heath J. K., Betsholtz C.and Richardson, W. D (1998). Oligodendrocyte population dynamics and the role of PDGF in vivo. Neuron 20, 869-882.[Medline]

Casaccia-Bonnefil, P., Tikoo, R., Kiyokawa, H., Friedrich, V., Chao, M. V. and Koff, A (1997). Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1. Genes Dev 11, 2335-2346.[Abstract/Free Full Text]

Clurman, B., Sheaff, R., Thress, K., Groudine, M. and Roberts, J (1996). Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by CDK2 binding and cyclin phosphorylation. Genes Dev 10, 1979-1990.[Abstract/Free Full Text]

Curtis, R., Cohen, J., Fok-Seang, J., Hanley, M., Gregson, N., Reynolds, R. and Wilkin, G (1988). Development of macroglial cells in rat cerebellum.I. Use of antibodies to follow early in vivo development and migration of oligodendrocytes. J. Neurocytol 17, 51-59.

de Nooij, J., Letendre, M. and Hariharan, I (1996). A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis. Cell 87, 1237-1247.[Medline]

Demerens, C., Stankoff, B., Logak, M., Anglade, P. M., Alliquant, B., Courad, F., Zalc, B. and Lubetzki, C (1996). Induction of myelination in the central nervous system by electrical activity. Proc. Natl. Acad. Sci.USA 93, 9887-9892.[Abstract/Free Full Text]

Durand, B., Fero, M. L., Roberts, J. M. and Raff, M. C (1998). p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation. Curr. Biol 8, 431-440.[Medline]

Durand, B., Gao, F.-B. and Raff, M (1997). Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation. EMBO J 16, 306-317.[Medline]

Duronio, R. and O'Farrell, P (1995). Developmental control of the G1 to S transition in Drosophila: cyclin E is a limiting downstream target of E2F. Genes Dev 9, 1456-1468.[Abstract/Free Full Text]

Edgar, A. and Pfeiffer, S (1985). Extracts from neuron-enriched cultures of chick telencephalon stimulate the proliferation of rat oligodendrocytes. Dev. Neurosci 7, 206-215.[Medline]

Fero, M. L., Rivkin, M., Tasch, M., Porter, P., Carow, C. E., Firpo, E., Polyak, K., Tsai, L.-H., Broudy, V., Perlmutter, R. M. et al (1996). A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27Kip1-deficient mice. Cell 85, 733-744.[Medline]

Gallo, V. and Russel, J. T (1995). Excitatory amino acid receptor in glia. Different subtypes for distinct functions?. J. Neurosci. Res 42, 1-8.[Medline]

Gao, F.-B. and Raff, M (1997). Oligodendrocyte precursor cells count time but not cell divisions before differentiation. Curr. Biol 7, 152-155.[Medline]

Gao, F.-B., Apperly, J. andRaff, M (1998). Cell-intrinsic timers and thyroid hormone regulate the probability of cell-cycle withdrawal and differentiation of oligodendrocyte precursor cells. Dev. Biol 197, 54-66.[Medline]

Gard, A. L. and Pfeiffer, S. E (1990). Two proliferative stages of the oligodendrocyte lineage (A2B5+O4and O4+GalC ) under different mitogenic control. Neuron 5, 615-625.[Medline]

Ghiani, C. A., Eisen, A. M., Yuan, X., DePinho, R. A., McBain, C. J. and Gallo, V (1999). Neurotransmitter receptor activation triggers p27kip1 and p21cip1 accumulation and G1 cell cycle arrest in oligodendrocyte progenitors. Development 126, 1077-1090.[Abstract]

Goldman, J., Zerlin, M., Newman, S., Zhang, L. and Gensert, J (1997). Fate determination and migration of progenitors in the postnatal mammalian CNS. Dev. Neurosci 19, 42-48.[Medline]

Hardy, R (1997). Dorsoventral patterning and oligodendroglial specification in the developing central nervous system. J. Neurosci. Res 50, 139-145.[Medline]

Hardy, R (1998). QKI expression is regulated during neuron-glial cell fate decisions. J. Neurosci. Res 54, 46-57.[Medline]

Hardy, R (1998). Molecular defects in the dysmyelinating mutant quaking. J. Neurosci. Res 51, 417-422.[Medline]

Hardy, R., Loushin, C., Friedrich, V. J., Chen, Q., Ebersole, T., Lazzarini, R. and Artzt, K (1996). Neural cell type-specific expression of QKI proteins is altered in quakingviable mutant mice. J. Neurosci 16, 7941-7949.[Abstract/Free Full Text]

Hardy, R. and Reynolds, R (1991). Proliferation and differentiation potential of rat forebrain oligodendroglial progenitors both in vitro and in vivo. Development 111, 1061-1080.[Abstract/Free Full Text]

Hardy, R. and Reynolds, R (1993). Neuron-oligodendroglial interactions during central nervous system development. J. Neurosci. Res 36, 121-126.[Medline]

Hong, Y., Roy R. and Ambros, V (1998). Developmental regulation of a cyclin-dpendent kinase inhibitor controls cell cycle progression in Caenorhabditis elegans. Development 125, 3585-3597.[Abstract]

Ibarrola, N., Mayer-Proschel, M., Rodriguez-Pena, A. and Noble, M (1996). Evidence for the existence of at least two timing mechanisms that contribute to oligodendrocyte generation in vitro. Dev. Biol 180, 1-21.[Medline]

Jacques, T., Relvas, J., Nishimura, S., Pytela, R., Edwards, G. M., Streuli, C. and ffrench-Constant, C (1998). Neural precursor chain migration and division are regulated through different beta1-integrins. Development 125, 3167-3177.[Abstract]

Kiyokawa, H., Kineman, R. D., Manova-Todorova, K. O., Soares, V. C., Hoffman, E. S., Ono, M., Khanam, D., Hayday, A. C., Frohman, L. A. and Koff, A (1996). Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27kip1. Cell 85, 721-732.[Medline]

Kiyokawa, H., Richon, V., Rifkind, R. and Marks, P (1994). Suppression of cyclin-dependent kinase 4 (CDK4) during induced differentiation of erythroleukemia cells. Mol. Cell Biol 14, 7195-7203.[Abstract/Free Full Text]

Knoblich, J., Sauer, K., Jones, L., Richardson, H., Saint, R. and Lehner, C. F (1994). Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell 77, 107-120.[Medline]

Lane, M., Sauer K, Wallace K, Jan, Y., Lehner, C. and Vaessin, H (1996). Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell 87, 1225-1235.[Medline]

Levine, J. and Stallcup, W. B (1987). Plasticity of developing cerebellar cells in vitro studied with antibodies against the NG2 antigen. J. Neurosci 7, 2721-2731.[Abstract]

Levine, J. M., Stincone, F. and Lee, Y. S (1993). Development and differentiation of glial precursor cells in the rat cerebellum. Glia 7, 307-321.[Medline]

Levison, S., Chuang, C., Abramson, B. and Goldman, J (1993). The migrational patterns and developmental fates of glial precursors in the ratsubventricular zone are temporally regulated. Development 119, 611-622.[Abstract]

Levison, S. and Goldman, J (1993). Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain. Neuron 10, 201-212.[Medline]

Luskin, M. and McDermott, K (1994). Divergent lineages for oligodendrocytes and astrocytes in the neonatal forebrain subventricular zone. Glia 11, 211-226.[Medline]

Miller, R. H (1996). Oligodendrocyte origins. Trends Neurosci 19, 92-96.[Medline]

Miyajima, M., Nornes, H. and Neuman, T (1995). Cyclin E is expressed in neurons and forms complexes with cdk5. Neuroreport 6, 1130-1132.[Medline]

Nakayama, K., Isshida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Horii, I., Loh, D. and Nakayama, K.-I (1996). Mice lacking p27kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85, 707-720.[Medline]

Neufeld, T. P., de la Cruz, A. F. A., Johnston, L. A. and Edgar, B. A (1998). Coordination of growth and cell division in the drosophila wing. Cell 93, 1183-1193.[Medline]

Nornes, H. and Carry, M (1978). Neurogenesis in spinal cord of mouse:an autoradiographic analysis. Brain Res 159, 1-16.[Medline]

Nornes, H. and Das, G (1974). Temporal pattern of neurogenesis in spinal cord of rat. I. An autoradiographic study-Time and sites of origin and migration and settling patterns of neuroblasts. Brain Res 73, 121-138.[Medline]

Pringle, N., Guthrie, S., Lumsden, A. and Richardson, W (1998). Dorsal spinal cord neuroepithelium generates astrocytes but not oligodendrocytes. Neuron 20, 883-893.[Medline]

Pringle, N. P., Yu, W.-P., Guthrie, S., Roelink, H., Lumsden, A., Peterson, A. C. and Richardson, W. D (1996). Determination of neuroepithelial cell fate: Induction of the oligodendrocyte lineage by ventral midline cells and sonic hedgehog. Dev. Biol 177, 30-42.[Medline]

Raff, M. C (1996). Size control: The regulation of cell numbers in animal development. Cell 86, 173-175.[Medline]

Reynolds, R. and Wilkin, G (1991). Oligodendroglial progenitor cells but not oligodendroglia divide during normal development of the rat cerebellum. J. Neurocytol 20, 216-224.[Medline]

Reynolds, R. and Wilkin, G. P (1988). Development of macroglial cells in rat cerebellum II. An in situ immunohistochemical study of oligodendroglial lineage from precursor to mature myelinating cells. Development 102, 409-425.[Abstract]

Richardson, W., Pringle, N., Yu, W. and Hall, A (1997). Origins of spinal cord oligodendrocytes: possible developmental and evolutionary relationship with motor neurons. Dev. Neurosci 19, 58-68.[Medline]

Ross, M (1996). Cell division and the nervous system:regulating the cycle from neural differentiation to death. Trends Neurosci 19, 62-68.[Medline]

Ross, M. and Risken, M (1994). MN20, a D2 cyclin found in brain, is implicated in neural differentiation. J. Neurosci 14, 6384-6391.[Abstract]

Ross, M. E., Carter, M. L. and Lee, J. H (1996). MN20, a D2 cyclin, is transiently expressed in selected neural populations during embryogenesis. J. Neurosci 16, 210-219.[Abstract/Free Full Text]

Sherr, C. J. and Roberts, J. M (1995). Inhibitors of mammalian G1 cyclin-dependent kinases. Genes and Dev 79, 551-555.

Tang, X., Strocchi, P. and Cambi, F (1998). Changes in the activity of cdk2 and cdk5 accompany differentiation of rat primary oligodendrocytes. J. Cell. Biochem 68, 128-137.[Medline]

Temple, S. and Raff, M. C (1986). Clonal analysis of oligodendrocyte development in culture:evidence for a developmental clock that counts cell divisions. Cell 44, 773-779.[Medline]

Tikoo, R., Osterhout, D. J., Casaccia-Bonnefil, P., Seth, P., Koff, A. and Chao, M. V (1998). Ectopic expression of p27Kip1in oligodendrocyte progenitor cells results in cell cycle growth arrest. J. Neurobiol 36, 431-440.[Medline]

Timsit, S., Martinez, S., Allinquant, B., Peyron, F., Puelles, L. and Zalc, B (1995). Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tubedefined by DM-20 mRNA expression. J. Neurosci 15, 1012-1024.[Abstract]

Vlach, J., Hennecke, S. and Amati, B (1997). Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1. EMBO J 16, 5334-5344.[Medline]

Wang, S., Sdrulla AD, diSibio G, Bush G, Nofziger D, Hicks, C., Weinmaster, G. and Barres, B (1998). Notch receptor activation inhibits oligodendrocyte differentiation. Neuron 21, 63-75.[Medline]

Wood, P. and Bunge, R (1986). Evidence that axons are mitogenic for oligodendrocytes isolated from adult animals. Nature 320, 756-758.[Medline]

Yuan, X., Eisen, A. M., McBain, C. J. and Gallo, V (1998). A role for glutamate and its receptors in the regulation of oligodendrocyte development in cerebellar tisuue slices. Development 125, 2901-2914.[Abstract]

Zavitz, H. K. and Zipursky, S. L (1997). Controlling cell proliferation in differentiating tissues:genetic analysis of negative regulators of G1-S phase progression. Curr. Opin. Cell Biol 9, 773-781.[Medline]

Zerlin, M., Levison, S. and Goldman, J (1995). Early patterns of migration, morphogenesis, and intermeduate filament expression of subventricular zone cells in the postnatal rat forebrain. J. Neurosci 15, 7238-7249.[Abstract]

Zindy, F., Soares, H., Herzog, K.-H., Morgan, J., Sherr, C. J. and Roussel, M. F (1997). Expression of INK4 inhibitors of cyclin D-dependent kinases during mouse brain development. Cell Growth Differ 8, 1139-1150.[Abstract]

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				Y. Chen, D. Tian, L. Ku, D. J. Osterhout, and Y. Feng The Selective RNA-binding Protein Quaking I (QKI) Is Necessary and Sufficient for Promoting Oligodendroglia Differentiation J. Biol. Chem., August 10, 2007; 282(32): 23553 - 23560. [Abstract] [Full Text] [PDF]

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				J. C. Dugas, A. Ibrahim, and B. A. Barres A Crucial Role for p57Kip2 in the Intracellular Timer that Controls Oligodendrocyte Differentiation J. Neurosci., June 6, 2007; 27(23): 6185 - 6196. [Abstract] [Full Text] [PDF]

				L. Zhao, D. Tian, M. Xia, W. B. Macklin, and Y. Feng Rescuing qkv Dysmyelination by a Single Isoform of the Selective RNA-Binding Protein QKI. J. Neurosci., November 1, 2006; 26(44): 11278 - 11286. [Abstract] [Full Text] [PDF]

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				Y.-S. Lee, F. Liu, and N. Segil A morphogenetic wave of p27Kip1 transcription directs cell cycle exit during organ of Corti development Development, August 1, 2006; 133(15): 2817 - 2826. [Abstract] [Full Text] [PDF]

				T. Tarui, T. Takahashi, R.S. Nowakowski, N.L. Hayes, P.G. Bhide, and V.S. Caviness Overexpression of p27Kip1, Probability of Cell Cycle Exit, and Laminar Destination of Neocortical Neurons Cereb Cortex, September 1, 2005; 15(9): 1343 - 1355. [Abstract] [Full Text] [PDF]

				V. Bryja, L. Cajanek, J. Pachernik, A. C. Hall, V. Horvath, P. Dvorak, and A. Hampl Abnormal Development of Mouse Embryoid Bodies Lacking p27Kip1 Cell Cycle Regulator Stem Cells, August 1, 2005; 23(7): 965 - 974. [Abstract] [Full Text] [PDF]

				H.-C. Park, J. Boyce, J. Shin, and B. Appel Oligodendrocyte Specification in Zebrafish Requires Notch-Regulated Cyclin-Dependent Kinase Inhibitor Function J. Neurosci., July 20, 2005; 25(29): 6836 - 6844. [Abstract] [Full Text] [PDF]

				B. Dasgupta and D. H. Gutmann Neurofibromin Regulates Neural Stem Cell Proliferation, Survival, and Astroglial Differentiation In Vitro and In Vivo J. Neurosci., June 8, 2005; 25(23): 5584 - 5594. [Abstract] [Full Text] [PDF]

				S. Shen, J. Li, and P. Casaccia-Bonnefil Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain J. Cell Biol., May 23, 2005; 169(4): 577 - 589. [Abstract] [Full Text] [PDF]

				A. Chittka, J. C. Arevalo, M. Rodriguez-Guzman, P. Perez, M. V. Chao, and M. Sendtner The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E J. Cell Biol., March 29, 2004; 164(7): 985 - 996. [Abstract] [Full Text] [PDF]

				S. Sell Mouse Models to Study the Interaction of Risk Factors for Human Liver Cancer Cancer Res., November 15, 2003; 63(22): 7553 - 7562. [Abstract] [Full Text] [PDF]

				J. Imitola, E. Y. Snyder, and S. J. Khoury Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis Physiol Genomics, August 15, 2003; 14(3): 171 - 197. [Abstract] [Full Text] [PDF]

				M. Marin-Husstege, M. Muggironi, A. Liu, and P. Casaccia-Bonnefil Histone Deacetylase Activity Is Necessary for Oligodendrocyte Lineage Progression J. Neurosci., December 1, 2002; 22(23): 10333 - 10345. [Abstract] [Full Text] [PDF]

				F. Doetsch, J. M.-G. Verdugo, I. Caille, A. Alvarez-Buylla, M. V. Chao, and P. Casaccia-Bonnefil Lack of the Cell-Cycle Inhibitor p27Kip1 Results in Selective Increase of Transit-Amplifying Cells for Adult Neurogenesis J. Neurosci., March 15, 2002; 22(6): 2255 - 2264. [Abstract] [Full Text] [PDF]

				R. G. Carey, B. Li, and E. DiCicco-Bloom Pituitary Adenylate Cyclase Activating Polypeptide Anti-Mitogenic Signaling in Cerebral Cortical Progenitors Is Regulated by p57Kip2-Dependent CDK2 Activity J. Neurosci., March 1, 2002; 22(5): 1583 - 1591. [Abstract] [Full Text] [PDF]

				I. Kostic and R. Roy Organ-specific cell division abnormalities caused by mutation in a general cell cycle regulator in C. elegans Development, January 5, 2002; 129(9): 2155 - 2165. [Abstract] [Full Text] [PDF]

				M.-E. Legrier, A. Ducray, A. Propper, M. Chao, and A. Kastner Cell Cycle Regulation during Mouse Olfactory Neurogenesis Cell Growth Differ., December 1, 2001; 12(12): 591 - 601. [Abstract] [Full Text] [PDF]

				V. Coskun and M. B. Luskin The Expression Pattern of the Cell Cycle Inhibitor p19INK4d by Progenitor Cells of the Rat Embryonic Telencephalon and Neonatal Anterior Subventricular Zone J. Neurosci., May 1, 2001; 21(9): 3092 - 3103. [Abstract] [Full Text] [PDF]

				C. A. Ghiani and V. Gallo Inhibition of Cyclin E-Cyclin-Dependent Kinase 2 Complex Formation and Activity Is Associated with Cell Cycle Arrest and Withdrawal in Oligodendrocyte Progenitor Cells J. Neurosci., February 15, 2001; 21(4): 1274 - 1282. [Abstract] [Full Text] [PDF]

				R. Tikoo, G. Zanazzi, D. Shiffman, J. Salzer, and M. V. Chao Cell Cycle Control of Schwann Cell Proliferation: Role of Cyclin-Dependent Kinase-2 J. Neurosci., June 15, 2000; 20(12): 4627 - 4634. [Abstract] [Full Text] [PDF]