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Alexandre, C., Jacinto, A. and Ingham, P. W (1996). Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the Cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. Genes Dev 10, 2003-2013.[Abstract/Free Full Text]

Brand, A. H. and Perrimon, N (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.[Abstract]

Brou, C., Chaudhary, S., Davidson, I., Lutz, Y., Wu, J., Egly, J.-M., Tora, L. and Chambon, P (1993). Distinct TFIID complexes mediate the effect of different transcriptional activators. EMBO J 12, 489-499.[Medline]

Chen, Y., Gallaher, N., Goodman, R. H. and Smolik, S. M (1998). Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus. Proc. Natl. Acad. Sci. USA 95, 2349-2354.[Abstract/Free Full Text]

Cheng, H.-C., Kemp, B. E., Pearson, R. B., Smith, A. J., Misconi, L., Van Patten, S. M. and Walsh, D. A (1986). A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. J. Biol. Chem 261, 989-992.[Abstract/Free Full Text]

Dom\222nguez, M., Brunner, M., Hafen, E. and Basler, K (1996). Sending and receiving the hedgehog signal: control by the Drosophila Gli protein cubitus interruptus. Science 272, 1621-1625.[Abstract]

Fan, C.-M., Porter, J. A., Chiang, C., Chang, D. T., Beachy, P. A. andTessier-Lavigne, M (1995). Long-range sclerotome induction by Sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway. Cell 81, 457-465.[Medline]

Hammerschmidt, M., Bitgood, M. J. and McMahon, A. P (1996). Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes Dev 10, 647658-.

Ingham, P. W (1998). Transducing Hedgehog: the story so far. EMBO J 17, 3505-3511.[Medline]

Jiang, J. and Struhl, G (1998). Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature 391, 493-496.[Medline]

Johnson, R. L., Grenier, J. K. and Scott, M. P (1995). patched overexpression alters wing disc size and pattern: transcriptional and post-transcriptional effects on hedgehog targets. Development 121, 4161-4170.[Abstract]

Krishnan, V., Pereira, F. A., Qiu, Y., Chen, C. H., Beachy, P. A., Tsai, S. Y. and Tsai, M. J (1997). Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase. Science 278, 1947-1950.[Abstract/Free Full Text]

Li, W., Ohlmeyer, J. T., Lane, M. E. and Kalderon, D (1995). Function of protein kinase A in Hedgehog signal transduction and Drosophila imaginal disc development. Cell 80, 553-562.[Medline]

Maniatis, T (1999). A ubiquitin ligase complex essential for the NF-B, Wnt/Wingless, and Hedgehog signaling pathways. Genes Dev 13, 505-510.[Free Full Text]

Methot, N. and Basler, K (1999). Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. Cell 96, 819-831.[Medline]

Monnier, V., Dussillol, F., Alves, G., Lamour-Isnard, C. and Plessis, A (1998). Supressor of fused links Fused and Cubitus interruptus on the Hedgehog signalling pathway. Current Biol 8, 583-586.[Medline]

Motzny, C. K. and Holmgren, R (1995). The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways. Mech. Dev 52, 137-150.[Medline]

Ohlmeyer, J. T. and Kalderon, D (1997). Dual pathways for induction of wingless expression by protein kinase A and Hedgehog in Drosophila embryos. Genes Dev 11, 2250-2258.[Abstract/Free Full Text]

Ohlmeyer, J. T. and Kalderon, D (1998). Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator. Nature 396, 749-753.[Medline]

Orenic, T. V., Slusarski, D. C., Kroll, K. L. and Holmgren, R. A (1990). Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila. Genes Dev 4, 1053-1067.[Abstract/Free Full Text]

Robbins, D. J., Nybakken, K. E., Kobayashi, R., Sisson, J. C., Bishop, J. M. and Therond, P. P (1997). Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein Costal2. Cell 90, 225-234.[Medline]

Ruiz i Altaba, A (1999). Gli proteins encode context-dependent positive and negative functions: implications for development and disease. Development 126, 3205-3216.[Abstract]

Ruppert, J. M., Vogelstein, B., Arheden, K. and Kinzler, K. W (1990). GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity. Mol. Cell. Biol 10, 5408-5414.[Abstract/Free Full Text]

Sisson, J. C., Ho, K. S., Suyama, K. and Scott, M. P (1997). Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway. Cell 90, 235-245.[Medline]

Slusarski, D. C., Motzny, C. K. and Holmgren, R (1995). Mutations that alter the timing and pattern of cubitusinterruptus gene expression in Drosophilamelanogaster. Genetics 139, 229-240.[Abstract]

Theodosiou, N. A., Zhang, S., Wang, W. Y. and Xu, T (1998). slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development. Development 125, 3411-3416.[Abstract]

Therond, P. P., Knight, J. D., Kornberg, T. and Bishop, J. M (1996). Phosphorylation of the Fused protein kinase in response to signaling from hedgehog. Proc. Natl. Acad. Sci. USA 93, 4224-4228.[Abstract/Free Full Text]

Walsh, D. A. and Van Patten, S. M (1994). Multiple pathway signal transduction by the cAMP-dependent protein kinase. FASEB J 8, 1227-1236.[Abstract]

Yoffe, K. B., Manoukian, A. S., Wilder, E. S., Brand, A. H. and Perrimon, N (1995). Evidence for engrailed -independent wingless autoregulation in Drosophila. Dev. Biol 170, 636-650.[Medline]


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