A requirement for neuropilin-1 in embryonic vessel formation

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Ashwell, K (1991). The distribution of microglia and cell death in the fetal rat forebrain. Dev. Brain Res 58, 1-12.[Medline]

Behar, O., Golden, J. A., Mashimo, H., Schoen, F. J. and Fishman, M. C (1996). Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature 383, 525-528.[Medline]

Breier, G., Albrecht, U., Sterrer, S. and Risau W (1992). Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development 114, 521-532.[Abstract]

Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Eberhardt, C., Declercq, C., Pawling, J., Moons, L., Collen, D., Risau, W. and Nagy, A (1996). Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380, 435-439.[Medline]

Conway, S. J., Henderson, D. J. and Copp, A. J (1997). Pax3 is required for cardiac neural crest migration in the mouse: evidence from the splotch ( Sp2H ) mutant. Development 124, 505-514.[Abstract]

de Vries, C., Escobedo, J. A., Ueno, H., Houck, K., Ferrara, N. and Williams, L. T (1992). The fms -like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255, 986-991.[Abstract/Free Full Text]

Eickholt, B. J., Mackenzie, S. L., Graham, A., Walsh, F. S. and Doherty, P (1999). Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions. Development 126, 2181-2189.[Abstract]

Ferrara, N. and Henzel, W. J (1989). Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem. Biophys. Res. Commun 161, 851-858.[Medline]

Ferrara, N., Carver-Moore, K., Chen, H., Dowd, M., Lu, L., S. O'Shea, K., Powell-Braxton, L., Hillan, K. J. and Moore, M. W (1996). Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380, 439-442.[Medline]

Fong, G.-H., Rossant, J., Gertsenstein, M. and Breitman, M. L (1995). Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascularendothelium. Nature 376, 66-70.[Medline]

Fujisawa, H. and Kitsukawa, T (1998). Receptors for collapsin/semaphorins. Curr. Opin. Neurobiol 8, 587-592.[Medline]

Giger, R. J., Urquhart, E. R., Gillespie, S. K., Levengood, D. V., Ginty, D. D. and Kolodkin, A. L (1998). Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity. Neuron 21, 1079-1092.[Medline]

He Z. and Tessier-Lavigne, M (1997). Neuropilin is a receptor for the axonal chemorepellent semaphorin III. Cell 90, 739-751.[Medline]

Johnson, M. C., Payne, R. M., Grant, J. W. and Strauss, A. W (1995). The genetic basis of paediatric heart disease. Ann. Med 27, 289-300.[Medline]

Kawakami, A., Kitsukawa, T., Takagi, S. and Fujisawa, H (1996). Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system. J. Neurobiol 29, 1-17.[Medline]

Keck, P. J., Hauser, S. D., Krive, G., Sanzo, K., Warren, T., Feder, J. and Connolly, D. T (1989). Vascular permeability factor, and endothelial cell mitogen related to PDGF. Science 246, 1309-1312.[Abstract/Free Full Text]

Kitsukawa, T., Shimizu, M., Sanbo, M., Hirata, T., Taniguchi, M., Bekku, Y., Yagi, T. and Fujisawa, H (1997). Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron 19, 995-1005.[Medline]

Kitsukawa, T., Shimono, A., Kawakami, A., Kondoh, H. and Fujisawa, H (1995). Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limb. Development 121, 4309-4318.[Abstract]

Kolodkin, A. L., Levengood, D. V., Rowe, E. G., Tai, Y.-T., Giger, R. J. and Ginty, D. D (1997). Neuropilin is a semaphorin III receptor. Cell 90, 753-762.[Medline]

Kurihara, Y., Kurihara, H., Oda, H., Maemura, K., Nagai, R., Ishikawa, T. and Yazaki, Y (1995). Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1. J. Clin. Invest 96, 293-300.

Le Lievre, C. S. and Le Douarin, N. M (1975). Mesenchymal derivatives of the neural crest: analysis of chimaeric quail and chick embryos. J. Embryol. exp. Morph 34, 125-154.[Medline]

Leung, D. W., Cachianes, G., Kuang, W.-J., Goeddel, D. V. and Ferrara, N (1989). Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246, 1306-1309.[Abstract/Free Full Text]

Lindsay, E. A. and Baldini, A (1998). Congenital heart defects and 22q11 deletions: which genes count?. Mol. Med. Today 4, 350-357.[Medline]

Matsuda, Y. and Chapman, V. M (1995). Application of fluorescence in situ hybridization in genome analysis of the mouse. Electrophoresis 16, 261-272.[Medline]

Matsuda, Y., Harada, Y.-N., Natsuume-Sakai, S., Lee, K., Shiomi, T. and Chapman, V. M (1992). Location of the mouse complement factor H gene ( cfh ) by FISH analysis and replication R-banding. Cytogenet. Cell Genet 61, 282-285.[Medline]

Matthews, W., Jordan, C. T., Gavin, M., Jenkins, N. A., Copeland, N. G. and Lemischka, I. R (1991). A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc. Natl. Acad. Sci.USA 88, 9026-9030.[Abstract/Free Full Text]

Mendelsohn, C., Lohnes, D., Decimo, D., Lufkin, T., LeMeur, M., Pierre Chambon, P. and Mark, M (1994). Function of the retinoic acid receptors (RARs) during development. (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 120, 2749-2771.[Abstract]

Miao, H. Q., Soker, S., Feiner, L., Alonso, J. L., Raper, J. A. and Klagsbrun, M (1999). Neuropilin-1 mediates collapsin-1/Semaphorin III inhibition of endothelial cell motility. Functional competition of collapsin-1 and vascular endothelial growth factor-165. J. Cell Biol 146, 233-242.[Abstract/Free Full Text]

Migdal, M., Huppertz, B., Tessler, S., Comforti, A., Shibuya, M., Reich, R., Baumann, H. and Neufeld, G (1998). Neuropilin-1 is a placenta growth factor-2 receptor. J. Biol. Chem 273, 22272-22278.[Abstract/Free Full Text]

Millauer, B., Wizigmann-Voos, S., Schnurch, H., Martinez, R., M\257ller, N. P. H., Risau, W. and Ullrich, A (1993). High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72, 835-846.[Medline]

Miyagawa, S. and Kirby, M. L (1989). Pathogenesis of persistent truncusarteriosus induced by nimustine hydrochloride in chick embryos. Teratology 39, 287-294.[Medline]

Miyagawa-Tomita, S., Waldo, K., Tomita, H. and Kirby, M. L (1991). Temporospatial study of the migration and distribution of cardiac neural crest in quail-chick chimeras. Am. J. Anat 192, 79-88.[Medline]

Nishibatake, M., Kirby, M. L. and Van Mierop, L. H (1987). Pathogenesis of persistent truncus arteriosus and dextroposed aorta in the chick embryo after neural crest ablation. Circulation 75, 255-264.[Abstract/Free Full Text]

Noden, D. M (1991). Origins and patterning of avian outflow tract endocardium. Development 111, 867-876.[Abstract/Free Full Text]

Okishima, T., Takamura, K., Matsuoka, Y., Ohdo, S. and Hayakawa, K (1992). Cardiovascular anomalies in chick embryos produced by bis-diamine in dimethylsulfoxide. Teratology 45, 155-162.[Medline]

Quinn, T. P., Peters, K. G., de Vries, C., Ferrare, N. and Williams, L. T (1993). Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc. Natl. Acad. Sci. USA 90, 7533-7537.[Abstract/Free Full Text]

Risau, W (1997). Mechanisms of angiogenesis. Nature 386, 671-674.[Medline]

Rossignol, M., Beggs, A. H., Pierce, E. A. and Klagsbrun, M (1999). Human neuropilin-1 and neuropilin-2 map to 10p12 and 2q34, respectively. Genomics 57, 459-460.[Medline]

Satoh, H., Yoshida, M. C. and Sasaki, M (1989). High resolution chromosome banding in the Norway rat, Rattus norvegicus. Cytogenet. Cell Genet 50, 151-154.[Medline]

Schlaeger, T. M., Qin, Y., Fujiwara, Y., Magram, J. and Sato, T. N (1995). Vascular endothelial cell lineage-specific promoter in transgenic mice. Development 121, 1089-1098.[Abstract]

Serikawa, T., Cui, Z., Yokoi, N., Kuramoto, T., Kondo, Y., Kitada, K. and Guenet, J.-A (1998). A comparative genetic map of rat, mouse and human genomes. Exp. Anim 47, 1-9.[Medline]

Shalaby, F., Ho, J., Stanford, W. L., Fischer, K.-D., Schuh, A., C., Schwartz, L., Bernstein, A. and Rossant, J (1997). A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89, 981-990.[Medline]

Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X.-F., Breitman, M. L. and Schuh, A. C (1995). Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376, 62-66.[Medline]

Shibuya, M., Yamaguchi, S., Yamane, A., Ikeda, T., Tojo, A., Matsushima, H. and Sato, M (1990). Neucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene ( flt ) closely related to the fms family. Oncogene 5, 519-524.[Medline]

Soker, S., Takashima, S., Miao, H. Q., Neufeld, G. and Klagsbrun, M (1998). Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92, 735-745.[Medline]

Takagi S., Kasuya, Y., Shimizu, M., Matsuura, T., Tsuboi, M., Kawakami, A. and Fujisawa H (1995). Expression of a cell adhesion molecule, neuropilin, in the developing chick nervous system. Dev. Biol 170, 207-222.[Medline]

Takagi, S., Hirata, T., Agata, K., Mochii, M., Eguchi, G. and Fujisawa, H (1991). The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors. Neuron 7, 295-307.[Medline]

Takagi, S., Tsuji, T., Amagai, T., Takamatsu, T. and Fujisawa, H (1987). Specific cell surface labels in the visual centers of Xenopus laevis tadpole identified using monoclonal antibodies. Dev. Biol 122, 90-100.[Medline]

Taniguchi, M., Yuasa, S., Fujisawa, H., Naruse, I., Saga, S., Mishina, M. and Yagi, T (1997). Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection. Neuron 19, 519-530.[Medline]

Terman, B. I., Carrion, M. E., Kovacs, E., Rasmussen, B. A., Eddy, R. L. and Shows, T. B (1991). Identification of a new endothelial cell growth factor receptor tyrosine kinase. Oncogene 6, 1677-1683.[Medline]

Waldo, K. L. and Kirby, M. L (1993). Cardiac neural crest contribution to the pulmonary artery and sixth aortic arch artery complex in chick embryos aged 6 to 18 days. Anat. Rec 237, 385-399.[Medline]

Waldo, K., Miyagawa-Tomita, S., Kumiski, D. and Kirby, M. L (1998). Cardiac neural crest cells provide new insight into septation of the cardiac outflow tract: aortic sac to ventricular septal closure. Dev. Biol 196, 129-144.[Medline]

Yamada, J., Kuramoto, T. and Serikawa, T (1994). A rat genetic linkage map and comparative maps for mouse or human homologous rat genes. Mammalian Genome 5, 63-83.[Medline]

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[Abstract] [Full Text] [PDF]

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Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2
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[Abstract] [Full Text] [PDF]

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[Abstract] [Full Text] [PDF]

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J. Clin. Oncol., February 10, 2005; 23(5): 1011 - 1027.
[Abstract] [Full Text] [PDF]

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Semaphorin 3E and Plexin-D1 Control Vascular Pattern Independently of Neuropilins
Science, January 14, 2005; 307(5707): 265 - 268.
[Abstract] [Full Text] [PDF]

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Common Cues in Vascular and Axon Guidance
Physiology, December 1, 2004; 19(6): 348 - 354.
[Abstract] [Full Text] [PDF]

Q. Schwarz, C. Gu, H. Fujisawa, K. Sabelko, M. Gertsenstein, A. Nagy, M. Taniguchi, A. L. Kolodkin, D. D. Ginty, D. T. Shima, et al.
Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve
Genes & Dev., November 15, 2004; 18(22): 2822 - 2834.
[Abstract] [Full Text] [PDF]

M. Mura, C. C. dos Santos, D. Stewart, and M. Liu
Vascular endothelial growth factor and related molecules in acute lung injury
J Appl Physiol, November 1, 2004; 97(5): 1605 - 1617.
[Abstract] [Full Text] [PDF]

N. Ferrara
Vascular Endothelial Growth Factor: Basic Science and Clinical Progress
Endocr. Rev., August 1, 2004; 25(4): 581 - 611.
[Abstract] [Full Text] [PDF]

D. S. Rice, W. Huang, H. A. Jones, G. Hansen, G.-L. Ye, N. Xu, E. A. Wilson, K. Troughton, K. Vaddi, R. C. Newton, et al.
Severe Retinal Degeneration Associated with Disruption of Semaphorin 4A
Invest. Ophthalmol. Vis. Sci., August 1, 2004; 45(8): 2767 - 2777.
[Abstract] [Full Text] [PDF]

L. Cheng, H. Jia, M. Lohr, A. Bagherzadeh, D. I. R. Holmes, D. Selwood, and I. Zachary
Anti-chemorepulsive Effects of Vascular Endothelial Growth Factor and Placental Growth Factor-2 in Dorsal Root Ganglion Neurons Are Mediated via Neuropilin-1 and Cyclooxygenase-derived Prostanoid Production
J. Biol. Chem., July 16, 2004; 279(29): 30654 - 30661.
[Abstract] [Full Text] [PDF]

S. K. Dey, H. Lim, S. K. Das, J. Reese, B. C. Paria, T. Daikoku, and H. Wang
Molecular Cues to Implantation
Endocr. Rev., June 1, 2004; 25(3): 341 - 373.
[Abstract] [Full Text] [PDF]

				H. Kawamura, X. Li, S. J. Harper, D. O. Bates, and L. Claesson-Welsh Vascular Endothelial Growth Factor (VEGF)-A165b Is a Weak In vitro Agonist for VEGF Receptor-2 Due to Lack of Coreceptor Binding and Deficient Regulation of Kinase Activity Cancer Res., June 15, 2008; 68(12): 4683 - 4692. [Abstract] [Full Text] [PDF]

				Q. Schwarz, J. M. Vieira, B. Howard, B. J. Eickholt, and C. Ruhrberg Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells Development, May 1, 2008; 135(9): 1605 - 1613. [Abstract] [Full Text] [PDF]

				H. R. Lijnen Angiogenesis and obesity Cardiovasc Res, May 1, 2008; 78(2): 286 - 293. [Abstract] [Full Text] [PDF]

				G. Serini, L. Napione, M. Arese, and F. Bussolino Besides adhesion: new perspectives of integrin functions in angiogenesis Cardiovasc Res, May 1, 2008; 78(2): 213 - 222. [Abstract] [Full Text] [PDF]

				M. Narazaki, M. Segarra, and G. Tosato Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A Blood, April 15, 2008; 111(8): 4126 - 4136. [Abstract] [Full Text] [PDF]

				E. Sulpice, J. Plouet, M. Berge, D. Allanic, G. Tobelem, and T. Merkulova-Rainon Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity Blood, February 15, 2008; 111(4): 2036 - 2045. [Abstract] [Full Text] [PDF]

				A. G. Wright, G. P. Demyanenko, A. Powell, M. Schachner, L. Enriquez-Barreto, T. S. Tran, F. Polleux, and P. F. Maness Close Homolog of L1 and Neuropilin 1 Mediate Guidance of Thalamocortical Axons at the Ventral Telencephalon J. Neurosci., December 12, 2007; 27(50): 13667 - 13679. [Abstract] [Full Text] [PDF]

				N. Guttmann-Raviv, N. Shraga-Heled, A. Varshavsky, C. Guimaraes-Sternberg, O. Kessler, and G. Neufeld Semaphorin-3A and Semaphorin-3F Work Together to Repel Endothelial Cells and to Inhibit Their Survival by Induction of Apoptosis J. Biol. Chem., September 7, 2007; 282(36): 26294 - 26305. [Abstract] [Full Text] [PDF]

				E. Geretti, A. Shimizu, P. Kurschat, and M. Klagsbrun Site-directed Mutagenesis in the B-Neuropilin-2 Domain Selectively Enhances Its Affinity to VEGF165, but Not to Semaphorin 3F J. Biol. Chem., August 31, 2007; 282(35): 25698 - 25707. [Abstract] [Full Text] [PDF]

				Q. Pan, Y. Chathery, Y. Wu, N. Rathore, R. K. Tong, F. Peale, A. Bagri, M. Tessier-Lavigne, A. W. Koch, and R. J. Watts Neuropilin-1 Binds to VEGF121 and Regulates Endothelial Cell Migration and Sprouting J. Biol. Chem., August 17, 2007; 282(33): 24049 - 24056. [Abstract] [Full Text] [PDF]

				M. Ramsauer and P. A. D'Amore Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization J. Cell Sci., May 15, 2007; 120(10): 1810 - 1817. [Abstract] [Full Text] [PDF]

				J. M. Vieira, Q. Schwarz, and C. Ruhrberg Selective requirements for NRP1 ligands during neurovascular patterning Development, May 15, 2007; 134(10): 1833 - 1843. [Abstract] [Full Text] [PDF]

				N. M.S. van den Akker, D. G.M. Molin, P. P.W.M. Peters, S. Maas, L. J. Wisse, R. van Brempt, C. J. van Munsteren, M. M. Bartelings, R. E. Poelmann, P. Carmeliet, et al. Tetralogy of Fallot and Alterations in Vascular Endothelial Growth Factor-A Signaling and Notch Signaling in Mouse Embryos Solely Expressing the VEGF120 Isoform Circ. Res., March 30, 2007; 100(6): 842 - 849. [Abstract] [Full Text] [PDF]

				N. Shraga-Heled, O. Kessler, C. Prahst, J. Kroll, H. Augustin, and G. Neufeld Neuropilin-1 and neuropilin-2 enhance VEGF121 stimulated signal transduction by the VEGFR-2 receptor FASEB J, March 1, 2007; 21(3): 915 - 926. [Abstract] [Full Text] [PDF]

				F. Lanner, M. Sohl, and F. Farnebo Functional Arterial and Venous Fate Is Determined by Graded VEGF Signaling and Notch Status During Embryonic Stem Cell Differentiation Arterioscler. Thromb. Vasc. Biol., March 1, 2007; 27(3): 487 - 493. [Abstract] [Full Text] [PDF]

				E. Hochman, A. Castiel, J. Jacob-Hirsch, N. Amariglio, and S. Izraeli Molecular Pathways Regulating Pro-migratory Effects of Hedgehog Signaling J. Biol. Chem., November 10, 2006; 281(45): 33860 - 33870. [Abstract] [Full Text] [PDF]

				B. Favier, A. Alam, P. Barron, J. Bonnin, P. Laboudie, P. Fons, M. Mandron, J.-P. Herault, G. Neufeld, P. Savi, et al. Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration Blood, August 15, 2006; 108(4): 1243 - 1250. [Abstract] [Full Text] [PDF]

				T. Karpanen, C. A. Heckman, S. Keskitalo, M. Jeltsch, H. Ollila, G. Neufeld, L. Tamagnone, and K. Alitalo Functional interaction of VEGF-C and VEGF-D with neuropilin receptors FASEB J, July 1, 2006; 20(9): 1462 - 1472. [Abstract] [Full Text] [PDF]

				L. Wang, D. Mukhopadhyay, and X. Xu C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis FASEB J, July 1, 2006; 20(9): 1513 - 1515. [Abstract] [Full Text] [PDF]

				M. Narazaki and G. Tosato Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A Blood, May 15, 2006; 107(10): 3892 - 3901. [Abstract] [Full Text] [PDF]

				H. Jia, A. Bagherzadeh, B. Hartzoulakis, A. Jarvis, M. Lohr, S. Shaikh, R. Aqil, L. Cheng, M. Tickner, D. Esposito, et al. Characterization of a Bicyclic Peptide Neuropilin-1 (NP-1) Antagonist (EG3287) Reveals Importance of Vascular Endothelial Growth Factor Exon 8 for NP-1 Binding and Role of NP-1 in KDR Signaling J. Biol. Chem., May 12, 2006; 281(19): 13493 - 13502. [Abstract] [Full Text] [PDF]

				L. M. Ellis The role of neuropilins in cancer Mol. Cancer Ther., May 1, 2006; 5(5): 1099 - 1107. [Abstract] [Full Text] [PDF]

				M. N. Bekker, N. M. S. van den Akker, M. M. Bartelings, J. B. Arkesteijn, S. G. L. Fischer, J. A. E. Polman, M. C. Haak, S. Webb, R. E. Poelmann, J. M. G. van Vugt, et al. Nuchal Edema and Venous-Lymphatic Phenotype Disturbance in Human Fetuses and Mouse Embryos With Aneuploidy Reproductive Sciences, April 1, 2006; 13(3): 209 - 216. [Abstract] [PDF]

				A Abid, M Ismail, S Q Mehdi, and S Khaliq Identification of novel mutations in the SEMA4A gene associated with retinal degenerative diseases J. Med. Genet., April 1, 2006; 43(4): 378 - 381. [Abstract] [Full Text] [PDF]

				P. Kurschat, D. Bielenberg, M. Rossignol-Tallandier, A. Stahl, and M. Klagsbrun Neuron Restrictive Silencer Factor NRSF/REST Is a Transcriptional Repressor of Neuropilin-1 and Diminishes the Ability of Semaphorin 3A to Inhibit Keratinocyte Migration J. Biol. Chem., February 3, 2006; 281(5): 2721 - 2729. [Abstract] [Full Text] [PDF]

				C. K. Williams, J.-L. Li, M. Murga, A. L. Harris, and G. Tosato Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function Blood, February 1, 2006; 107(3): 931 - 939. [Abstract] [Full Text] [PDF]

				J.E. Ferguson III, R. W. Kelley, and C. Patterson Mechanisms of Endothelial Differentiation in Embryonic Vasculogenesis Arterioscler. Thromb. Vasc. Biol., November 1, 2005; 25(11): 2246 - 2254. [Abstract] [Full Text] [PDF]

				J. M. Proctor, K. Zang, D. Wang, R. Wang, and L. F. Reichardt Vascular Development of the Brain Requires {beta}8 Integrin Expression in the Neuroepithelium J. Neurosci., October 26, 2005; 25(43): 9940 - 9948. [Abstract] [Full Text] [PDF]

				D. Barberis, A. Casazza, R. Sordella, S. Corso, S. Artigiani, J. Settleman, P. M. Comoglio, and L. Tamagnone p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling J. Cell Sci., October 15, 2005; 118(20): 4689 - 4700. [Abstract] [Full Text] [PDF]

				M. Taniguchi, T. Masuda, M. Fukaya, H. Kataoka, M. Mishina, H. Yaginuma, M. Watanabe, and T. Shimizu Identification and characterization of a novel member of murine semaphorin family Genes Cells, August 1, 2005; 10(8): 785 - 792. [Abstract] [Full Text] [PDF]