PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development

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				N. J. Oviedo, B. J. Pearson, M. Levin, and A. Sanchez Alvarado Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling Dis. Model. Mech., September 1, 2008; 1(2-3): 131 - 143. [Abstract] [Full Text] [PDF]

				X. Ju, S. Katiyar, C. Wang, M. Liu, X. Jiao, S. Li, J. Zhou, J. Turner, M. P. Lisanti, R. G. Russell, et al. Akt1 governs breast cancer progression in vivo PNAS, May 1, 2007; 104(18): 7438 - 7443. [Abstract] [Full Text] [PDF]

				N. Vereshchagina and C. Wilson Cytoplasmic activated protein kinase Akt regulates lipid-droplet accumulation in Drosophila nurse cells Development, December 1, 2006; 133(23): 4731 - 4735. [Abstract] [Full Text] [PDF]

				L. Mahimainathan, F. Das, B. Venkatesan, and G. G. Choudhury Mesangial Cell Hypertrophy by High Glucose Is Mediated by Downregulation of the Tumor Suppressor PTEN. Diabetes, July 1, 2006; 55(7): 2115 - 2125. [Abstract] [Full Text] [PDF]

				A. Dekanty, S. Lavista-Llanos, M. Irisarri, S. Oldham, and P. Wappner The insulin-PI3K/TOR pathway induces a HIF-dependent transcriptional response in Drosophila by promoting nuclear localization of HIF-{alpha}/Sima J. Cell Sci., December 1, 2005; 118(23): 5431 - 5441. [Abstract] [Full Text] [PDF]

				Y. Yang, S. Gehrke, Md. E. Haque, Y. Imai, J. Kosek, L. Yang, M. F. Beal, I. Nishimura, K. Wakamatsu, S. Ito, et al. Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling PNAS, September 20, 2005; 102(38): 13670 - 13675. [Abstract] [Full Text] [PDF]

				W. von Stein, A. Ramrath, A. Grimm, M. Muller-Borg, and A. Wodarz Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling Development, April 1, 2005; 132(7): 1675 - 1686. [Abstract] [Full Text] [PDF]

				J. H. Reiling and E. Hafen The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila Genes & Dev., December 1, 2004; 18(23): 2879 - 2892. [Abstract] [Full Text] [PDF]

				D. K. Scheidenhelm and D. H. Gutmann Mouse Models of Tuberous Sclerosis Complex J Child Neurol, September 1, 2004; 19(9): 726 - 733. [Abstract] [PDF]

				R. D. Read, E. A. Bach, and R. L. Cagan Drosophila C-Terminal Src Kinase Negatively Regulates Organ Growth and Cell Proliferation through Inhibition of the Src, Jun N-Terminal Kinase, and STAT Pathways Mol. Cell. Biol., August 1, 2004; 24(15): 6676 - 6689. [Abstract] [Full Text] [PDF]

				L. Mahimainathan and G. G. Choudhury Inactivation of Platelet-derived Growth Factor Receptor by the Tumor Suppressor PTEN Provides a Novel Mechanism of Action of the Phosphatase J. Biol. Chem., April 9, 2004; 279(15): 15258 - 15268. [Abstract] [Full Text] [PDF]

				M. Raftopoulou, S. Etienne-Manneville, A. Self, S. Nicholls, and A. Hall Regulation of Cell Migration by the C2 Domain of the Tumor Suppressor PTEN Science, February 20, 2004; 303(5661): 1179 - 1181. [Abstract] [Full Text] [PDF]

				D. J. Emlen and C. E. Allen Genotype to Phenotype: Physiological Control of Trait Size and Scaling in Insects Integr. Comp. Biol., November 1, 2003; 43(5): 617 - 634. [Abstract] [Full Text] [PDF]

				J. Faridi, J. Fawcett, L. Wang, and R. A. Roth Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation Am J Physiol Endocrinol Metab, November 1, 2003; 285(5): E964 - E972. [Abstract] [Full Text] [PDF]

				D. C.I. Goberdhan and C. Wilson PTEN: tumour suppressor, multifunctional growth regulator and more Hum. Mol. Genet., October 15, 2003; 12(90002): R239 - 248. [Abstract] [Full Text] [PDF]

				S. Szuplewski, B. Kottler, and R. Terracol The Drosophila bZIP transcription factor Vrille is involved in hair and cell growth Development, August 15, 2003; 130(16): 3651 - 3662. [Abstract] [Full Text] [PDF]

				P. K. Majumder, J. J. Yeh, D. J. George, P. G. Febbo, J. Kum, Q. Xue, R. Bikoff, H. Ma, P. W. Kantoff, T. R. Golub, et al. Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: The MPAKT model PNAS, June 24, 2003; 100(13): 7841 - 7846. [Abstract] [Full Text] [PDF]

				D. J. Frank, B. A. Edgar, and M. B. Roth The Drosophila melanogaster gene brain tumor negatively regulates cell growth and ribosomal RNA synthesis Development, March 3, 2003; 129(2): 399 - 407. [Abstract] [Full Text] [PDF]

				R. Gupta, J. T. L. Ting, L. N. Sokolov, S. A. Johnson, and S. Luan A Tumor Suppressor Homolog, AtPTEN1, Is Essential for Pollen Development in Arabidopsis PLANT CELL, October 1, 2002; 14(10): 2495 - 2507. [Abstract] [Full Text] [PDF]

				S. Oldham, H. Stocker, M. Laffargue, F. Wittwer, M. Wymann, and E. Hafen The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP3 levels Development, September 1, 2002; 129(17): 4103 - 4109. [Abstract] [Full Text] [PDF]

				D. A. Prober and B. A. Edgar Interactions between Ras1, dMyc, and dPI3K signaling in the developing Drosophila wing Genes & Dev., September 1, 2002; 16(17): 2286 - 2299. [Abstract] [Full Text] [PDF]

				Z. Xu, D. Stokoe, L. P. Kane, and A. Weiss The Inducible Expression of the Tumor Suppressor Gene PTEN Promotes Apoptosis and Decreases Cell Size by Inhibiting the PI3K/Akt Pathway in Jurkat T Cells Cell Growth Differ., July 1, 2002; 13(7): 285 - 296. [Abstract] [Full Text]

				B. Stiles, V. Gilman, N. Khanzenzon, R. Lesche, A. Li, R. Qiao, X. Liu, and H. Wu Essential Role of AKT-1/Protein Kinase B{alpha} in PTEN-Controlled Tumorigenesis Mol. Cell. Biol., June 1, 2002; 22(11): 3842 - 3851. [Abstract] [Full Text] [PDF]

				J. Huang and C. D. Kontos PTEN Modulates Vascular Endothelial Growth Factor-Mediated Signaling and Angiogenic Effects J. Biol. Chem., March 22, 2002; 277(13): 10760 - 10766. [Abstract] [Full Text] [PDF]

				F. Rintelen, H. Stocker, G. Thomas, and E. Hafen PDK1 regulates growth through Akt and S6K in Drosophila PNAS, December 18, 2001; 98(26): 15020 - 15025. [Abstract] [Full Text] [PDF]

				M. Miron and N. Sonenberg Regulation of Translation via TOR Signaling: Insights from Drosophila melanogaster J. Nutr., November 1, 2001; 131(11): 2988S - 2993. [Abstract] [Full Text] [PDF]

				W. S. Chen, P.-Z. Xu, K. Gottlob, M.-L. Chen, K. Sokol, T. Shiyanova, I. Roninson, W. Weng, R. Suzuki, K. Tobe, et al. Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene Genes & Dev., September 1, 2001; 15(17): 2203 - 2208. [Abstract] [Full Text] [PDF]

				M. S. Neshat, I. K. Mellinghoff, C. Tran, B. Stiles, G. Thomas, R. Petersen, P. Frost, J. J. Gibbons, H. Wu, and C. L. Sawyers Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR PNAS, August 10, 2001; (2001) 171076798. [Abstract] [Full Text] [PDF]

				K. Podsypanina, R. T. Lee, C. Politis, I. Hennessy, A. Crane, J. Puc, M. Neshat, H. Wang, L. Yang, J. Gibbons, et al. An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice PNAS, August 10, 2001; (2001) 171060098. [Abstract] [Full Text] [PDF]

				A. H. Ross, M. B. Lachyankar, and L. D. Recht PTEN: A Newly Identified Regulator of Neuronal Differentiation Neuroscientist, August 1, 2001; 7(4): 278 - 281. [Abstract] [PDF]