Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries

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Afzelius, B. A (1976). A human syndrome caused by immotile cilia. Science 193, 317-319.[Abstract/Free Full Text]

Brown, N. A., Hoyle, C. I., McCarthy, A. and Wolpert, L (1989). The development of asymmetry: the sidedness of drug-induced limb abnormalities is reversed in situs inversus mice. Development 107, 637-642.[Abstract]

Brown, N. A. and Wolpert, L (1990). The development of handedness in left/right asymmetry. Development 109, 1-9.[Abstract]

Campione, M., Steinbeisser, H., Schweickert, A., Deissler, K., van Bebber, F., Lowe, L. A., Nowotshcin S., Viebahn, C., Haffter, P., Kuehn, M. R. and Blum, M (1999). The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping. Development 126, 1225-1234.[Abstract]

Collignon, J., Varlet, I. and Robertson, E. J (1996). Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature 381, 155-158.[Medline]

Danos, M. C. and Yost, H. J (1995). Linkage of cardiac left-right asymmetry and dorsal-anterior development in Xenopus. Development 121, 1467-1474.[Abstract]

Danos, M. C. and Yost, H. J (1996). Role of notochord in specification of cardiac left-right orientation in zebrafish and Xenopus. Dev. Biol 177, 96-103.[Medline]

Dufort, D., Schwartz, L., Harpal, K. and Rossant, J (1998). The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis. Development 125, 3015-3025.[Abstract]

Echelard, Y., Epstein, D.J., St-Jacques, B., Shen, L., Mohler, J., McMahon, J.A. and McMahon A.P (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.[Medline]

Gebbia, M., Ferrero, G. B., Pilia, G., Bassi, M. T., Aylsworth, A. S., Penman-Splitt, M., Bird, L. M., Bamforth, J. S., Burn, J., Schlessinger, D., Nelson, D. L. and Casey, B (1997). X-linked situs abnormalities result from mutations in ZIC3. Nature Gen 17, 305-308.[Medline]

Gee, M. A., Heuser, J. E. and Vallee, R. B (1997). An extended microtubule-binding structure within the dynein motor domain. Nature 390, 636-639.[Medline]

Gibbons, I. R., Gibbons, B. H., Mocz, G. and Asai, D. J (1991). Multiple nucleotide-binding sites in the sequence of dynein b heavy chain. Nature 352, 640-643.[Medline]

Goldstein, A. M., Ticho, B. S. and Fishman, M. C (1998). Patterning the heart's left-right axis: from zebrafish to man. Dev. Genet 22, 278-287.[Medline]

Handel, M. A. and Kennedy, J. R (1984). Situs inversus in homozygous mice without immotile cilia. J. Hered 75, 498-.[Abstract/Free Full Text]

Heymer, J., Kuehn, M. and Ruther, U (1997). The expression pattern of nodal and lefty in the mouse mutant Ft suggests a function in the establishment of handedness. Mech. Dev 66, 5-11.[Medline]

Holzbaur, E. L. F. and Vallee, R. B (1994). Dyneins: molecular structure and cellular function. Annu. Rev. Cell Biol 10, 339-372.

Hummel, K. P. and Chapman, D. B (1959). Visceral inversion and associated anomalies in the mouse. J. Hered 50, 9-13.[Free Full Text]

Hyatt, B. A. and Yost, H. J (1998). The left-right coordinator: the role of Vg1 in organizing left-right axis formation. Cell 93, 37-46.[Medline]

Isaac, A., Sargent, M. G. and Cooke, J (1997). Control of vertebrate left-right asymmetry by a Snail-related zinc finger gene. Science 275, 1301-1304.[Abstract/Free Full Text]

Izraeli, S., Lowe, L.A., Bertness, V., Good, D.J., Dorward, D.W. Kirsch, I.R. and Kuehn, M.R (1999). The SIL gene is required for mouse embryonic axial development and left-right specification. Nature 399, 691-694.[Medline]

Kandl, K. A., Forney, J. D. and Asai, D. J (1995). The dynein genes of Paramecium tetraurelia: the structure and expression of ciliaryand cytoplasmic heavy chains. Mol. Biol. Cell 6, 1549-1562.[Abstract]

King, T., Beddington, R. S. P. and Brown, N. A (1998). The role of the brachyury gene in heart development and left-right specification in the mouse. Mech. Dev 79, 29-37.[Medline]

Klar, A. J. S (1994). A model for specification of the left-right axis in vertebrates. Trends Genet 10, 392-396.[Medline]

Layton, W. M (1976). Random determination of a developmental process. J. Hered 67, 336-338.[Free Full Text]

Levin, M., Johnson, R. L., Stern, C. D., Kuehn, M. and Tabin, C (1995). A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 82, 803-814.[Medline]

Levin, M., Pagan, S., Roberts, D. J., Cooke, J., Kuehn, M. R. and Tabin, C. J (1997). Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo. Dev. Biol 189, 57-67.[Medline]

Levin, M. and Mercola, M (1998). The compulsion of chirality: toward an understanding of left-right asymmetry. Genes Dev 12, 763-769.[Free Full Text]

Logan, M., Pagan-Westphal, S. M., Smith, D. M., Paganessi, L. and Tabin, C. J (1998). The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals. Cell 94, 307-317.[Medline]

Lohr, J. L., Danos, M. C. and Yost, H. J (1997). Left-right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development. Development 124, 1465-1472.[Abstract]

Lowe, L. A., Supp, D. M., Sampath, K., Yokoyama, T., Wright, C. V. E., Potter, S. S., Overbeek, P. and Kuehn, M. R (1996). Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. Nature 381, 158-161.[Medline]

Marszalek J.R., Ruiz-Lozano P., Roberts E., Chien K.R. and Goldstein L.S (1999). Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc. Natl. Acad. Sci. USA 96, 5043-5048.[Abstract/Free Full Text]

McNeish, J. D., Thayer, J., Walling, K., Sulik, K. K., Potter, S. S. and Scott, W. J (1990). Phenotypic characterization of the transgenic mouse insertional mutation, legless. J. Exp. Zool 253, 151-162.[Medline]

Melloy, P. G., Ewart, J. L., Cohen, M. F., Desmond, M. E., Kuehn, M.R. and Lo, C. W (1998). No turning, a mouse mutation causing left-right and axial patterning defects. Dev. Biol 193, 77-89.[Medline]

Meno, C., Saijoh, Y., Fujii, H., Ikeda, M., Yokoyama, T., Yokoyama, M., Toyoda, Y. and Hamada, H (1996). Left-right asymmetric expressionofthe TGF-family member lefty in mouse embryos. Nature 381, 151-155.[Medline]

Meno, C., Shimono, A., Saijoh, Y., Yashiro, K., Mochida, K., Ohishi, S., Noji, S., Kondoh, H. and Hamada, H (1998). Lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell 94, 287-297.[Medline]

Metzler, M., Gertz, A., Sarkar, M., Schachter, H., Schrader, J. W. and Marth, J. D (1994). Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J 13, 2056-2065.[Medline]

Morris R. L. and Scholey J. M (1999). Heterotrimeric kinesin-II is required for the assembly of motile 9+2 ciliary axonemes on sea urchin embryos. J. Cell Biol 138, 1009-1022.[Abstract/Free Full Text]

Nonaka, S., Tanaka, Y., Okada, Y., Takeda, S., Harada, A., Kanai, Y., Kido, M. and Hirokawa, N (1998). Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95, 829-837.[Medline]

Pagan-Westphal, S. M. and Tabin, C. J (1998). The transfer of left-right positional information during chick embryogenesis. Cell 93, 25-35.[Medline]

Piedra, M. E., Icardo, J. M., Albajar, M., Rodriguez-Rey, J. C. and Ros, M. A (1998). Pitx2 participates in the late phase of the pathway controlling left-right asymmetry. Cell 94, 319-324.[Medline]

Ryan, A. K., Blumberg, B., Rodriquez-Esteban, C., Yonei-Tamura, S., Tamura, K., Tsukui, T., de la Pena, J., Sabbagh, W., Greenwald, J., Choe, S., Norris, D. P., Roberston, E. J., Evans, E. M., Rosenfeld, M. G. and Belmonte, J. C. I (1998). Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature 394, 545-551.[Medline]

Sefton, M., Sanchez, S. and Nieto, M. A (1998). Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo. Development 125, 3111-3121.[Abstract]

Splitt, M. P., Burn, J. and Goodship, J (1996). Defects in the determination of left-right asymmetry. J. Med. Genet 33, 498-503.[Free Full Text]

Srivastava, D (1997). Left, right... which way to turn?. Nat. Genet 17, 305-308.

Supp, D. M., Witte, D. P., Branford, W. W., Smith, E. P. and Potter, S. S (1996). Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility. Dev. Biol 176, 284-299.[Medline]

Supp, D. M., Witte, D. P., Potter, S. S. and Brueckner, M (1997). Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice. Nature 389, 963-966.[Medline]

Takeda, S., Yonekawa, Y., Tanaka, Y., Okada, Y., Nonaka, S. and Hirokawa, N (1999). Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A/ mice analysis. J. Cell Biol 145, 825-836.[Abstract/Free Full Text]

Vogan, K. J. and Tabin, C. J (1999). A new spin on handed asymmetry. Nature 397, 295-298.[Medline]

Wheatley, D. N., Wang, A. M. and Strugnell, G. E (1996). Expression of primary cilia in mammalian cells. Cell Biol. Inter 20, 73-81.[Medline]

Yokoyama, T., Copeland, N. G., Jenkins, N. A., Montgomery, C. A., Elder, F. F. B. and Overbeek, P. A (1993). Reversal of left-right asymmetry; a situs inversus mutation. Science 260, 679-682.[Abstract/Free Full Text]

Yoshioka, H., Meno, C., Koshiba, K, Sugihara, M., Itoh, H., Ishimaru, Y., Inoue, T., Ohuchi, H., Semina, E. V., Murray, J. C., Hamada, H. and Noji, S (1998). Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry. Cell 94, 299-330.[Medline]

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				M. K. Tayeh, H.-J. Yen, J. S. Beck, C. C. Searby, T. A. Westfall, H. Griesbach, V. C. Sheffield, and D. C. Slusarski Genetic interaction between Bardet-Biedl syndrome genes and implications for limb patterning Hum. Mol. Genet., July 1, 2008; 17(13): 1956 - 1967. [Abstract] [Full Text] [PDF]

				C. M Freisinger, I. Schneider, T. A Westfall, and D. C Slusarski Calcium dynamics integrated into signalling pathways that influence vertebrate axial patterning Phil Trans R Soc B, April 12, 2008; 363(1495): 1377 - 1385. [Abstract] [Full Text] [PDF]

				I. Schneider, D. W. Houston, M. R. Rebagliati, and D. C. Slusarski Calcium fluxes in dorsal forerunner cells antagonize -catenin and alter left-right patterning Development, January 1, 2008; 135(1): 75 - 84. [Abstract] [Full Text] [PDF]

				B. Sarmah, V. P. Winfrey, G. E. Olson, B. Appel, and S. R. Wente A role for the inositol kinase Ipk1 in ciliary beating and length maintenance PNAS, December 11, 2007; 104(50): 19843 - 19848. [Abstract] [Full Text] [PDF]

				A. Livraghi and S. H. Randell Cystic Fibrosis and Other Respiratory Diseases of Impaired Mucus Clearance Toxicol Pathol, January 1, 2007; 35(1): 116 - 129. [Abstract] [Full Text] [PDF]

				B. W. Bisgrove and H. J. Yost The roles of cilia in developmental disorders and disease Development, November 1, 2006; 133(21): 4131 - 4143. [Abstract] [Full Text] [PDF]

				H. Shiratori and H. Hamada The left-right axis in the mouse: from origin to morphology Development, June 1, 2006; 133(11): 2095 - 2104. [Abstract] [Full Text] [PDF]

				H.-J. Yen, M. K. Tayeh, R. F. Mullins, E. M. Stone, V. C. Sheffield, and D. C. Slusarski Bardet-Biedl syndrome genes are important in retrograde intracellular trafficking and Kupffer's vesicle cilia function Hum. Mol. Genet., March 1, 2006; 15(5): 667 - 677. [Abstract] [Full Text] [PDF]

				M.-a. Nakaya, K. Biris, T. Tsukiyama, S. Jaime, J. A. Rawls, and T. P. Yamaguchi Wnt3alinks left-right determination with segmentation and anteroposterior axis elongation Development, December 15, 2005; 132(24): 5425 - 5436. [Abstract] [Full Text] [PDF]

				W. J. Weninger, K. L. Floro, M. B. Bennett, S. L. Withington, J. I. Preis, J. P. M. Barbera, T. J. Mohun, and S. L. Dunwoodie Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development Development, March 15, 2005; 132(6): 1337 - 1348. [Abstract] [Full Text] [PDF]

				J. J. Essner, J. D. Amack, M. K. Nyholm, E. B. Harris, and H. J. Yost Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut Development, March 15, 2005; 132(6): 1247 - 1260. [Abstract] [Full Text] [PDF]

				A. A. Rana, J. P. M. Barbera, T. A. Rodriguez, D. Lynch, E. Hirst, J. C. Smith, and R. S. P. Beddington Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates Development, October 15, 2004; 131(20): 4999 - 5007. [Abstract] [Full Text] [PDF]

				S. Marques, A. C. Borges, A. C. Silva, S. Freitas, M. Cordenonsi, and J. A. Belo The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis Genes & Dev., October 1, 2004; 18(19): 2342 - 2347. [Abstract] [Full Text] [PDF]

				M. Levin THE EMBRYONIC ORIGINS OF LEFT-RIGHT ASYMMETRY Critical Reviews in Oral Biology & Medicine, July 1, 2004; 15(4): 197 - 206. [Abstract] [Full Text] [PDF]

				E. Bonnafe, M. Touka, A. AitLounis, D. Baas, E. Barras, C. Ucla, A. Moreau, F. Flamant, R. Dubruille, P. Couble, et al. The Transcription Factor RFX3 Directs Nodal Cilium Development and Left-Right Asymmetry Specification Mol. Cell. Biol., May 15, 2004; 24(10): 4417 - 4427. [Abstract] [Full Text] [PDF]

				S. M. Bell, C. M. Schreiner, R. R. Waclaw, K. Campbell, S. S. Potter, and W. J. Scott From the Cover: Sp8 is crucial for limb outgrowth and neuropore closure PNAS, October 14, 2003; 100(21): 12195 - 12200. [Abstract] [Full Text] [PDF]

				D. Watanabe, Y. Saijoh, S. Nonaka, G. Sasaki, Y. Ikawa, T. Yokoyama, and H. Hamada The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia Development, May 1, 2003; 130(9): 1725 - 1734. [Abstract] [Full Text] [PDF]

				I. Ibanez-Tallon, N. Heintz, and H. Omran To beat or not to beat: roles of cilia in development and disease Hum. Mol. Genet., April 2, 2003; 12(90001): R27 - 35. [Abstract] [Full Text] [PDF]

				C. J. Tabin and K. J. Vogan A two-cilia model for vertebrate left-right axis specification Genes & Dev., January 1, 2003; 17(1): 1 - 6. [Full Text] [PDF]

				D. Morgan, L. Eley, J. Sayer, T. Strachan, L. M. Yates, A. S. Craighead, and J. A. Goodship Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle Hum. Mol. Genet., December 15, 2002; 11(26): 3345 - 3350. [Abstract] [Full Text] [PDF]

				L. Bartoloni, J.-L. Blouin, Y. Pan, C. Gehrig, A. K. Maiti, N. Scamuffa, C. Rossier, M. Jorissen, M. Armengot, M. Meeks, et al. Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia PNAS, August 6, 2002; 99(16): 10282 - 10286. [Abstract] [Full Text] [PDF]

				J. Neesen, R. Kirschner, M. Ochs, A. Schmiedl, B. Habermann, C. Mueller, A. F. Holstein, T. Nuesslein, I. Adham, and W. Engel Disruption of an inner arm dynein heavy chain gene results in asthenozoospermia and reduced ciliary beat frequency Hum. Mol. Genet., May 1, 2001; 10(11): 1117 - 1128. [Abstract] [Full Text] [PDF]

				P. D. Taulman, C. J. Haycraft, D. F. Balkovetz, and B. K. Yoder Polaris, a Protein Involved in Left-Right Axis Patterning, Localizes to Basal Bodies and Cilia Mol. Biol. Cell, March 1, 2001; 12(3): 589 - 599. [Abstract] [Full Text]

				G. Rupp, E. O'Toole, and M. E. Porter The Chlamydomonas PF6 Locus Encodes a Large Alanine/Proline-Rich Polypeptide That Is Required for Assembly of a Central Pair Projection and Regulates Flagellar Motility Mol. Biol. Cell, March 1, 2001; 12(3): 739 - 751. [Abstract] [Full Text]

				J. A. Spencer, S. Eliazer, R. L. Ilaria Jr., J. A. Richardson, and E. N. Olson Regulation of Microtubule Dynamics and Myogenic Differentiation by Murf, a Striated Muscle Ring-Finger Protein J. Cell Biol., August 21, 2000; 150(4): 771 - 784. [Abstract] [Full Text] [PDF]

				R. D. Burdine and A. F. Schier Conserved and divergent mechanisms in left-right axis formation Genes & Dev., April 1, 2000; 14(7): 763 - 776. [Full Text]

				S. King AAA domains and organization of the dynein motor unit J. Cell Sci., January 7, 2000; 113(14): 2521 - 2526. [Abstract] [PDF]