Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault

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				D. Bouvard, A. Aszodi, G. Kostka, M. R. Block, C. Albiges-Rizo, and R. Fassler Defective osteoblast function in ICAP-1-deficient mice Development, July 15, 2007; 134(14): 2615 - 2625. [Abstract] [Full Text] [PDF]

				C. Li, D. A. Scott, E. Hatch, X. Tian, and S. L. Mansour Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development Development, January 1, 2007; 134(1): 167 - 176. [Abstract] [Full Text] [PDF]

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				A. Mansukhani, D. Ambrosetti, G. Holmes, L. Cornivelli, and C. Basilico Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation J. Cell Biol., March 28, 2005; 168(7): 1065 - 1076. [Abstract] [Full Text] [PDF]

				Y. Tanimoto, M. Yokozeki, K. Hiura, K. Matsumoto, H. Nakanishi, T. Matsumoto, P. J. Marie, and K. Moriyama A Soluble Form of Fibroblast Growth Factor Receptor 2 (FGFR2) with S252W Mutation Acts as an Efficient Inhibitor for the Enhanced Osteoblastic Differentiation Caused by FGFR2 Activation in Apert Syndrome J. Biol. Chem., October 29, 2004; 279(44): 45926 - 45934. [Abstract] [Full Text] [PDF]

				V. P. Eswarakumar, M. C. Horowitz, R. Locklin, G. M. Morriss-Kay, and P. Lonai A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis PNAS, August 24, 2004; 101(34): 12555 - 12560. [Abstract] [Full Text] [PDF]

				S. R. F. Twigg, R. Kan, C. Babbs, E. G. Bochukova, S. P. Robertson, S. A. Wall, G. M. Morriss-Kay, and A. O. M. Wilkie Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome PNAS, June 8, 2004; 101(23): 8652 - 8657. [Abstract] [Full Text] [PDF]

				G. Valverde-Franco, H. Liu, D. Davidson, S. Chai, H. Valderrama-Carvajal, D. Goltzman, D. M. Ornitz, and J. E. Henderson Defective bone mineralization and osteopenia in young adult FGFR3-/- mice Hum. Mol. Genet., February 1, 2004; 13(3): 271 - 284. [Abstract] [Full Text] [PDF]

				M. K. Hajihosseini, M. D. Lalioti, S. Arthaud, H. R. Burgar, J. M. Brown, S. R. F. Twigg, A. O. M. Wilkie, and J. K. Heath Skeletal development is regulated by fibroblast growth factor receptor 1 signalling dynamics Development, January 15, 2004; 131(2): 325 - 335. [Abstract] [Full Text] [PDF]

				M. I. Reinhold, D. G. McEwen, and M. C. Naski Fibroblast Growth Factor Receptor 3 Gene: Regulation by Serum Response Factor Mol. Endocrinol., January 1, 2004; 18(1): 241 - 251. [Abstract] [Full Text] [PDF]

				C. M. Cowan, N. Quarto, S. M. Warren, A. Salim, and M. T. Longaker Age-related Changes in the Biomolecular Mechanisms of Clvarial Osteoblast Biology Affect Fibroblast Growth Factor-2 Signaling and Osteogenesis J. Biol. Chem., August 22, 2003; 278(34): 32005 - 32013. [Abstract] [Full Text] [PDF]

				N. Bobola, M. Carapuco, S. Ohnemus, B. Kanzler, A. Leibbrandt, A. Neubuser, J. Drouin, and M. Mallo Mesenchymal patterning by Hoxa2 requires blocking Fgf-dependent activation of Ptx1 Development, August 1, 2003; 130(15): 3403 - 3414. [Abstract] [Full Text] [PDF]

				K. Yu, J. Xu, Z. Liu, D. Sosic, J. Shao, E. N. Olson, D. A. Towler, and D. M. Ornitz Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth Development, July 1, 2003; 130(13): 3063 - 3074. [Abstract] [Full Text] [PDF]

				V. P. Eswarakumar, E. Monsonego-Ornan, M. Pines, I. Antonopoulou, G. M. Morriss-Kay, and P. Lonai The IIIc alternative of Fgfr2 is a positive regulator of bone formation Development, March 10, 2003; 129(16): 3783 - 3793. [Abstract] [Full Text] [PDF]

				H.-J. Kim, J.-H. Kim, S.-C. Bae, J.-Y. Choi, H.-J. Kim, and H.-M. Ryoo The Protein Kinase C Pathway Plays a Central Role in the Fibroblast Growth Factor-stimulated Expression and Transactivation Activity of Runx2 J. Biol. Chem., January 3, 2003; 278(1): 319 - 326. [Abstract] [Full Text] [PDF]

				D. M. Ornitz and P. J. Marie FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease Genes & Dev., June 15, 2002; 16(12): 1446 - 1465. [Full Text] [PDF]

				Z. Liu, J. Xu, J. S. Colvin, and D. M. Ornitz Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18 Genes & Dev., April 1, 2002; 16(7): 859 - 869. [Abstract] [Full Text] [PDF]

				N. Ohbayashi, M. Shibayama, Y. Kurotaki, M. Imanishi, T. Fujimori, N. Itoh, and S. Takada FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis Genes & Dev., April 1, 2002; 16(7): 870 - 879. [Abstract] [Full Text] [PDF]

				D. Kobayashi, M. Kobayashi, K. Matsumoto, T. Ogura, M. Nakafuku, and K. Shimamura Early subdivisions in the neural plate define distinct competence for inductive signals Development, January 1, 2002; 129(1): 83 - 93. [Abstract] [Full Text] [PDF]

				Q. Wang, R. P. Green, G. Zhao, and D. M. Ornitz Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains Development, October 1, 2001; 128(19): 3867 - 3876. [Abstract] [Full Text] [PDF]

				J. Lemonnier, E. Hay, P. Delannoy, O. Fromigue, A. Lomri, D. Modrowski, and P. J. Marie Increased Osteoblast Apoptosis in Apert Craniosynostosis : Role of Protein Kinase C and Interleukin-1 Am. J. Pathol., May 1, 2001; 158(5): 1833 - 1842. [Abstract] [Full Text] [PDF]

				M. K. Hajihosseini, S. Wilson, L. De Moerlooze, and C. Dickson A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes PNAS, March 27, 2001; 98(7): 3855 - 3860. [Abstract] [Full Text] [PDF]

				J. A. Greenwald, B. J. Mehrara, J. A. Spector, S. M. Warren, P. J. Fagenholz, L. P. Smith, P. J. Bouletreau, F. E. Crisera, H. Ueno, and M. T. Longaker In Vivo Modulation of FGF Biological Activity Alters Cranial Suture Fate Am. J. Pathol., February 1, 2001; 158(2): 441 - 452. [Abstract] [Full Text] [PDF]

				K. Yu, A. B. Herr, G. Waksman, and D. M. Ornitz Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome PNAS, December 19, 2000; 97(26): 14536 - 14541. [Abstract] [Full Text] [PDF]

				Y.-X. Zhou, X. Xu, L. Chen, C. Li, S. G. Brodie, and C.-X. Deng A Pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures Hum. Mol. Genet., August 12, 2000; 9(13): 2001 - 2008. [Abstract] [Full Text] [PDF]

				A. Mansukhani, P. Bellosta, M. Sahni, and C. Basilico Signaling by Fibroblast Growth Factors (FGF) and Fibroblast Growth Factor Receptor 2 (FGFR2)-activating Mutations Blocks Mineralization and Induces Apoptosis in Osteoblasts J. Cell Biol., June 12, 2000; 149(6): 1297 - 1308. [Abstract] [Full Text] [PDF]

				R Haraguchi, K Suzuki, R Murakami, M Sakai, M Kamikawa, M Kengaku, K Sekine, H Kawano, S Kato, N Ueno, et al. Molecular analysis of external genitalia formation: the role of fibroblast growth factor (Fgf) genes during genital tubercle formation Development, January 6, 2000; 127(11): 2471 - 2479. [Abstract] [PDF]