Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord

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				T. Harada, C. Harada, and L. F. Parada Molecular regulation of visual system development: more than meets the eye Genes & Dev., February 15, 2007; 21(4): 367 - 378. [Abstract] [Full Text] [PDF]

				A. R. Taylor, D. J. Gifondorwa, J. M. Newbern, M. B. Robinson, J. L. Strupe, D. Prevette, R. W. Oppenheim, and C. E. Milligan Astrocyte and Muscle-Derived Secreted Factors Differentially Regulate Motoneuron Survival J. Neurosci., January 17, 2007; 27(3): 634 - 644. [Abstract] [Full Text] [PDF]

				P. Podlesniy, A. Kichev, C. Pedraza, J. Saurat, M. Encinas, B. Perez, I. Ferrer, and C. Espinet Pro-NGF from Alzheimer's Disease and Normal Human Brain Displays Distinctive Abilities to Induce Processing and Nuclear Translocation of Intracellular Domain of p75NTR and Apoptosis Am. J. Pathol., July 1, 2006; 169(1): 119 - 131. [Abstract] [Full Text] [PDF]

				H. Rosch, R. Schweigreiter, T. Bonhoeffer, Y.-A. Barde, and M. Korte The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus PNAS, May 17, 2005; 102(20): 7362 - 7367. [Abstract] [Full Text] [PDF]

				M. S. Linggi, T. L. Burke, B. B. Williams, A. Harrington, R. Kraemer, B. L. Hempstead, S. O. Yoon, and B. D. Carter Neurotrophin Receptor Interacting Factor (NRIF) Is an Essential Mediator of Apoptotic Signaling by the p75 Neurotrophin Receptor J. Biol. Chem., April 8, 2005; 280(14): 13801 - 13808. [Abstract] [Full Text] [PDF]

				C. E. Pedraza, P. Podlesniy, N. Vidal, J. C. Arevalo, R. Lee, B. Hempstead, I. Ferrer, M. Iglesias, and C. Espinet Pro-NGF Isolated from the Human Brain Affected by Alzheimer's Disease Induces Neuronal Apoptosis Mediated by p75NTR Am. J. Pathol., February 1, 2005; 166(2): 533 - 543. [Abstract] [Full Text] [PDF]

				E. C. Yeiser, N. J. Rutkoski, A. Naito, J.-i. Inoue, and B. D. Carter Neurotrophin Signaling through the p75 Receptor Is Deficient in traf6-/- Mice J. Neurosci., November 17, 2004; 24(46): 10521 - 10529. [Abstract] [Full Text] [PDF]

				A. Colquhoun, G. M. Lawrance, I. L. Shamovsky, R. J. Riopelle, and G. M. Ross Differential Activity of the Nerve Growth Factor (NGF) Antagonist PD90780 [7-(Benzolylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic Acid] Suggests Altered NGF-p75NTR Interactions in the Presence of TrkA J. Pharmacol. Exp. Ther., August 1, 2004; 310(2): 505 - 511. [Abstract] [Full Text] [PDF]

				A. L. Bhakar, J. L. Howell, C. E. Paul, A. H. Salehi, E. B. E. Becker, F. Said, A. Bonni, and P. A. Barker Apoptosis Induced by p75NTR Overexpression Requires Jun Kinase-Dependent Phosphorylation of Bad J. Neurosci., December 10, 2003; 23(36): 11373 - 11381. [Abstract] [Full Text] [PDF]

				C. I. Dubreuil, M. J. Winton, and L. McKerracher Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system J. Cell Biol., July 21, 2003; 162(2): 233 - 243. [Abstract] [Full Text] [PDF]

				A. H. Salehi, S. Xanthoudakis, and P. A. Barker NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway J. Biol. Chem., December 6, 2002; 277(50): 48043 - 48050. [Abstract] [Full Text] [PDF]

				R. Kraemer Reduced Apoptosis and Increased Lesion Development in the Flow-Restricted Carotid Artery of p75NTR-Null Mutant Mice Circ. Res., September 20, 2002; 91(6): 494 - 500. [Abstract] [Full Text] [PDF]

				M. Palmada, S. Kanwal, N.J. Rutkoski, C. Gustafson-Brown, R.S. Johnson, R. Wisdom, and B.D. Carter c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation J. Cell Biol., August 5, 2002; 158(3): 453 - 461. [Abstract] [Full Text] [PDF]

				T. Naumann, E. Casademunt, E. Hollerbach, J. Hofmann, G. Dechant, M. Frotscher, and Y.-A. Barde Complete Deletion of the Neurotrophin Receptor p75NTR Leads to Long-Lasting Increases in the Number of Basal Forebrain Cholinergic Neurons J. Neurosci., April 1, 2002; 22(7): 2409 - 2418. [Abstract] [Full Text] [PDF]

				A. B. Brann, M. Tcherpakov, I. M. Williams, A. H. Futerman, and M. Fainzilber Nerve Growth Factor-induced p75-mediated Death of Cultured Hippocampal Neurons Is Age-dependent and Transduced through Ceramide Generated by Neutral Sphingomyelinase J. Biol. Chem., March 15, 2002; 277(12): 9812 - 9818. [Abstract] [Full Text] [PDF]

				D. B. Parkinson, Z. Dong, H. Bunting, J. Whitfield, C. Meier, H. Marie, R. Mirsky, and K. R. Jessen Transforming Growth Factor beta (TGFbeta ) Mediates Schwann Cell Death In Vitro and In Vivo: Examination of c-Jun Activation, Interactions with Survival Signals, and the Relationship of TGFbeta -Mediated Death to Schwann Cell Differentiation J. Neurosci., November 1, 2001; 21(21): 8572 - 8585. [Abstract] [Full Text] [PDF]

				M. F. DeFreitas, P. S. McQuillen, and C. J. Shatz A Novel p75NTR Signaling Pathway Promotes Survival, Not Death, of Immunopurified Neocortical Subplate Neurons J. Neurosci., July 15, 2001; 21(14): 5121 - 5129. [Abstract] [Full Text] [PDF]

				N. Dunker, N. Schuster, and K. Krieglstein TGF-{beta} modulates programmed cell death in the retina of the developing chick embryo Development, June 1, 2001; 128(11): 1933 - 1942. [Abstract] [Full Text] [PDF]

				M Karlsson, R Mayordomo, L. Reichardt, S Catsicas, H Karten, and F Hallbook Nerve growth factor is expressed by postmitotic avian retinal horizontal cells and supports their survival during development in an autocrine mode of action Development, January 2, 2001; 128(4): 471 - 479. [Abstract] [PDF]

				S. W. Wang, B. S. Kim, K. Ding, H. Wang, D. Sun, R. L. Johnson, W. H. Klein, and L. Gan Requirement for math5 in the development of retinal ganglion cells Genes & Dev., January 1, 2001; 15(1): 24 - 29. [Abstract] [Full Text]

				M. Bibel and Y.-A. Barde Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system Genes & Dev., December 1, 2000; 14(23): 2919 - 2937. [Full Text]

				S. Wang, P. Bray, T. McCaffrey, K. March, B. L. Hempstead, and R. Kraemer p75NTR Mediates Neurotrophin-Induced Apoptosis of Vascular Smooth Muscle Cells Am. J. Pathol., October 1, 2000; 157(4): 1247 - 1258. [Abstract] [Full Text] [PDF]

				J. J. Gentry, P. Casaccia-Bonnefil, and B. D. Carter Nerve Growth Factor Activation of Nuclear Factor kappa B through Its p75 Receptor Is an Anti-apoptotic Signal in RN22 Schwannoma Cells J. Biol. Chem., March 10, 2000; 275(11): 7558 - 7565. [Abstract] [Full Text] [PDF]

				J. Frade Unscheduled re-entry into the cell cycle induced by NGF precedes cell death in nascent retinal neurones J. Cell Sci., January 4, 2000; 113(7): 1139 - 1148. [Abstract] [PDF]

				C. Raoul, C. E. Henderson, and B. Pettmann Programmed Cell Death of Embryonic Motoneurons Triggered through the Fas Death Receptor J. Cell Biol., November 29, 1999; 147(5): 1049 - 1062. [Abstract] [Full Text] [PDF]

				P. P. Roux, M. A. Colicos, P. A. Barker, and T. E. Kennedy p75 Neurotrophin Receptor Expression Is Induced in Apoptotic Neurons After Seizure J. Neurosci., August 15, 1999; 19(16): 6887 - 6896. [Abstract] [Full Text] [PDF]

				A. L. Bhakar, P. P. Roux, C. Lachance, D. Kryl, C. Zeindler, and P. A. Barker The p75 Neurotrophin Receptor (p75NTR) Alters Tumor Necrosis Factor-mediated NF-kappa B Activity under Physiological Conditions, but Direct p75NTR-mediated NF-kappa B Activation Requires Cell Stress J. Biol. Chem., July 23, 1999; 274(30): 21443 - 21449. [Abstract] [Full Text] [PDF]

				P. P. Roux, A. L. Bhakar, T. E. Kennedy, and P. A. Barker The p75 Neurotrophin Receptor Activates Akt (Protein Kinase B) through a Phosphatidylinositol 3-Kinase-dependent Pathway J. Biol. Chem., June 15, 2001; 276(25): 23097 - 23104. [Abstract] [Full Text] [PDF]