BMPs negatively regulate structure and function of the limb apical ectodermal ridge

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				T. P. Hill, M. M. Taketo, W. Birchmeier, and C. Hartmann Multiple roles of mesenchymal {beta}-catenin during murine limb patterning Development, April 1, 2006; 133(7): 1219 - 1229. [Abstract] [Full Text] [PDF]

				P. Lu, G. Minowada, and G. R. Martin Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function Development, January 1, 2006; 133(1): 33 - 42. [Abstract] [Full Text] [PDF]

				C. Lours and S. Dietrich The dissociation of the Fgf-feedback loop controls the limbless state of the neck Development, December 15, 2005; 132(24): 5553 - 5564. [Abstract] [Full Text] [PDF]

				E. B. Johnson, R. E. Hammer, and J. Herz Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice Hum. Mol. Genet., November 15, 2005; 14(22): 3523 - 3538. [Abstract] [Full Text] [PDF]

				T. M. Williams, M. E. Williams, J. H. Heaton, T. D. Gelehrter, and J. W. Innis Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability Nucleic Acids Res., August 8, 2005; 33(14): 4475 - 4484. [Abstract] [Full Text] [PDF]

				Y. Lallemand, M.-A. Nicola, C. Ramos, A. Bach, C. S. Cloment, and B. Robert Analysis of Msx1; Msx2 double mutants reveals multiple roles for Msx genes in limb development Development, July 1, 2005; 132(13): 3003 - 3014. [Abstract] [Full Text] [PDF]

				L. Wine-Lee, K. J. Ahn, R. D. Richardson, Y. Mishina, K. M. Lyons, and E. B. Crenshaw III Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord Development, November 1, 2004; 131(21): 5393 - 5403. [Abstract] [Full Text] [PDF]

				Y. Kida, Y. Maeda, T. Shiraishi, T. Suzuki, and T. Ogura Chick Dach1 interacts with the Smad complex and Sin3a to control AER formation and limb development along the proximodistal axis Development, September 1, 2004; 131(17): 4179 - 4187. [Abstract] [Full Text] [PDF]

				D. G. Winkler, C. Yu, J. C. Geoghegan, E. W. Ojala, J. E. Skonier, D. Shpektor, M. K. Sutherland, and J. A. Latham Noggin and Sclerostin Bone Morphogenetic Protein Antagonists Form a Mutually Inhibitory Complex J. Biol. Chem., August 27, 2004; 279(35): 36293 - 36298. [Abstract] [Full Text] [PDF]

				P. J. Scherz, B. D. Harfe, A. P. McMahon, and C. J. Tabin The Limb Bud Shh-Fgf Feedback Loop Is Terminated by Expansion of Former ZPA Cells Science, July 16, 2004; 305(5682): 396 - 399. [Abstract] [Full Text] [PDF]

				O. Michos, L. Panman, K. Vintersten, K. Beier, R. Zeller, and A. Zuniga Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis Development, July 15, 2004; 131(14): 3401 - 3410. [Abstract] [Full Text] [PDF]

				K. Nogami, H. Suzuki, H. Habuchi, N. Ishiguro, H. Iwata, and K. Kimata Distinctive Expression Patterns of Heparan Sulfate O-Sulfotransferases and Regional Differences in Heparan Sulfate Structure in Chick Limb Buds J. Biol. Chem., February 27, 2004; 279(9): 8219 - 8229. [Abstract] [Full Text] [PDF]

				K. Suzuki, D. Bachiller, Y. P. Chen, M. Kamikawa, H. Ogi, R. Haraguchi, Y. Ogino, Y. Minami, Y. Mishina, K. Ahn, et al. Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia: development by concerted actions of BMP signaling Development, December 22, 2003; 130(25): 6209 - 6220. [Abstract] [Full Text] [PDF]

				M. Han, X. Yang, J. E. Farrington, and K. Muneoka Digit regeneration is regulated by Msx1 and BMP4 in fetal mice Development, November 1, 2003; 130(21): 5123 - 5132. [Abstract] [Full Text] [PDF]

				F. Gofflot, C. Hars, F. Illien, F. Chevy, C. Wolf, J. J. Picard, and C. Roux Molecular mechanisms underlying limb anomalies associated with cholesterol deficiency during gestation: implications of Hedgehog signaling Hum. Mol. Genet., May 15, 2003; 12(10): 1187 - 1198. [Abstract] [Full Text] [PDF]

				P. H.G. Duijf, H. van Bokhoven, and H. G. Brunner Pathogenesis of split-hand/split-foot malformation Hum. Mol. Genet., April 2, 2003; 12(90001): R51 - 60. [Abstract] [Full Text] [PDF]

				C. Liu, E. Nakamura, V. Knezevic, S. Hunter, K. Thompson, and S. Mackem A role for the mesenchymal T-box gene Brachyury in AER formation during limb development Development, April 1, 2003; 130(7): 1327 - 1337. [Abstract] [Full Text] [PDF]

				J. Ahn, L. Serrano de la Pena, E. M. Shore, and F. S. Kaplan Paresis of a Bone Morphogenetic Protein-Antagonist Response in a Genetic Disorder of Heterotopic Skeletogenesis J. Bone Joint Surg. Am., March 31, 2003; 85(4): 667 - 674. [Abstract] [Full Text] [PDF]

				Y. Liu, C. Liu, Y. Yamada, and C.-M. Fan growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb Development, March 13, 2003; 129(22): 5289 - 5300. [Abstract] [Full Text] [PDF]

				M. E. Piedra and M. A. Ros BMP signaling positively regulates Nodal expression during left right specification in the chick embryo Development, March 9, 2003; 129(14): 3431 - 3440. [Abstract] [Full Text] [PDF]

				J. R. Timmer, C. Wang, and L. Niswander BMP signaling patterns the dorsal and intermediate neural tube via regulation of homeobox and helix-loop-helix transcription factors Development, March 7, 2003; 129(10): 2459 - 2472. [Abstract] [Full Text] [PDF]

				A. M. Ashique, K. Fu, and J. M. Richman Endogenous bone morphogenetic proteins regulate outgrowth and epithelial survival during avian lip fusion Development, January 10, 2002; 129(19): 4647 - 4660. [Abstract] [Full Text] [PDF]

				S. Pizette, C. Abate-Shen, and L. Niswander BMP controls proximodistal outgrowth, via induction of the apical ectodermal ridge, and dorsoventral patterning in the vertebrate limb Development, November 15, 2001; 128(22): 4463 - 4474. [Abstract] [Full Text] [PDF]

				R. Haraguchi, R. Mo, C.-c. Hui, J. Motoyama, S. Makino, T. Shiroishi, W. Gaffield, and G. Yamada Unique functions of Sonic hedgehog signaling during external genitalia development Development, November 1, 2001; 128(21): 4241 - 4250. [Abstract] [Full Text] [PDF]

				R. Schweitzer, J. H. Chyung, L. C. Murtaugh, A. E. Brent, V. Rosen, E. N. Olson, A. Lassar, and C. J. Tabin Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments Development, October 1, 2001; 128(19): 3855 - 3866. [Abstract] [Full Text] [PDF]

				J. A. Montero, Y. Ganan, D. Macias, J. Rodriguez-Leon, J. J. Sanz-Ezquerro, R. Merino, J. Chimal-Monroy, M. A. Nieto, and J. M. Hurle Role of FGFs in the control of programmed cell death during limb development Development, June 1, 2001; 128(11): 2075 - 2084. [Abstract] [Full Text] [PDF]