Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain

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Abud, H. E., Skinner, J. A., McDonald, F. J., Bedford, M. T., Lonai, P. and Heath, J. K (1996). Ectopic expression of Fgf-4 in chimeric mouse embryos induces the expression of early markers of limb development in the lateral ridge. Dev. Genet 19, 51-65.[Medline]

Acampora, D., Avantaggiato, V., Tuorto, F. and Simeone, A (1997). Genetic control of brain morphogenesis through Otx gene dosage requirement. Development 124, 3639-3650.[Abstract]

Alvarado-Mallart, R.-M., Martinez, S. and Lance-Jones, C (1990). Pluripotentiality of the 2-day-old avian germinative neuroepithelium. Dev. Biol 139, 75-88.[Medline]

Alvarado-Mallart, R.-M. and Sotelo, C (1984). Homotopic and heterotopic transplantations of quail tectal primordia in chick embryos: organisation of the retinotectal projections in the chimeric embryos. Dev. Biol 103, 378-398.[Medline]

Alvarado-Mallart, R. M (1993). Fate and potentialities of the avian mesencephalic/metencephalic neuroepithelium. J. Neurobiol 24, 1341-1355.[Medline]

Alvarez, I. S., Araujo, M. and Nieto, M. A (1998). Neural induction in whole chick embryo cultures by FGF. Dev. Biol 199, 42-54.[Medline]

Alvarez-Otero, R., Sotelo, C. and Alvarado-Mallart, R.-M (1993). Chick/quail chimeras with partial cerebellar grafts: an analysis of the origin and migration of cerebellar cells. J. Comp. Neurol 333, 597-615.[Medline]

Ang, S. L. and Rossant, J (1993). Anterior mesendoderm induces mouse Engrailed genes in explant cultures. Development 118, 139-149.[Abstract]

Arman, E., Haffner-Krausz, R., Chen, Y., Heath, J. K. and Lonai, P (1998). Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc. Natl. Acad. Sci. USA 95, 5082-5087.[Abstract/Free Full Text]

Bally-Cuif, L., Alvarado-Mallart, R.-M., Darnell, D. K. and Wassef, M (1992). Relationship between Wnt-1 and En-2 expression domains during early development of normal and ectopic met-mesencephalon. Development 115, 999-1009.[Abstract]

Bally-Cuif, L. and Wassef, M (1994). Ectopic induction and reorganisation of Wnt-1 expression in quail/chick chimeras. Development 120, 3379-3394.[Abstract]

Bally-Cuif, L. and Wassef, M (1995). Determination events in the nervous system of the vertebrate embryo. Curr. Opin. Genet. Dev 5, 450-458.[Medline]

Bally-Cuif, L., Cholley, B. and Wassef, M (1995). Involvement of Wnt-1 in the formation of the mes/metencephalic boundary. Mech. Dev 53, 23-34.[Medline]

Bally-Cuif, L., Gulisano, M., Broccoli, V. and Boncinelli, E (1995). c-otx2 is expressed in two different phases of gastrulation and is sensitive to retinoic acid treatment in chick embryo. Mech Dev 49, 49-63.[Medline]

Bloch-Gallego, E., Millet, S. and Alvarado-Mallart, R. M (1996). Further observations on the susceptibility of diencephalic prosomeres to En-2 induction and on the resulting histogenetic capabilities. Mech. Dev 58, 51-63.[Medline]

Bueno, D., Skinner, J., Abud, H. and Heath, J. K (1996). Spatial and temporal relationships between Shh, Fgf4, and Fgf8 gene expression at diverse signalling centers during mouse development. Dev. Dyn 207, 291-299.[Medline]

Cheng, H. J. and Flanagan, J. G (1994). Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases. Cell 79, 157-168.[Medline]

Cheng, H.-J., Nakamoto, M., Bergemann, A. D. and Flanagan, J. D (1995). Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell 82, 371-381.[Medline]

Christen, B. and Slack, J. M (1997). FGF-8 is associated with anteroposterior patterning and limb regeneration in Xenopus. Dev. Biol 192, 455-466.[Medline]

Crossley, P. H. and Martin, G. R (1995). The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.[Abstract]

Crossley, P. H., Martinez, S. and Martin, G. R (1996). Midbrain development induced by FGF8 in the chick embryo. Nature 380, 66-68.[Medline]

Danielian, P. S. and McMahon, A. P (1996). Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature 383, 332-334.[Medline]

Darnell, D. K. and Schoenwolf, G. C (1997). Vertical induction of engrailed-2 and other region-specific markers in the early chick embryo. Dev. Dyn 209, 45-58.[Medline]

Davis, C. A., Holmyard, D. P., Millen, K. J. and Joyner, A. J (1991). Examining pattern formation in mouse, chick and frog embryos with an En -specific antiserum. Development 111, 287-298.[Abstract]

Deng, C.-X., Wynshaw-Boris, A., Shen, M., Daugherty, C., Ornitz, D. and Leder, P (1994). Murine FGFR-1 is required for early postimplantation growth and axial organisation. Genes Dev 8, 3045-3057.[Abstract/Free Full Text]

Doniach, T (1995). Basic FGF as an inducer of anteroposterior neural pattern. Cell 83, 1067-1070.[Medline]

Drescher, U., Kremoser, C., Handwerker, C., Loschinger, J., Noda, M. and Bonhoeffer, F (1995). In vitro guidance of retinal ganglion axons by RAGS, a 25kDa tectal protein related to ligands for eph receptor tyrosine kinases. Cell 82, 359-370.[Medline]

Dressler, G. R., Deutsch, U., Chowdhury, K., Nornes, H. O. and Gruss, P (1990). Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. Development 109, 787-795.[Abstract/Free Full Text]

Eizema, K., Koster, J. G., Stegeman, B. I., Baarends, W. M., Lanser, P. H. and Destree, O. H (1994). Comparative analysis of Engrailed-1 and Wnt-1 expression in the developing central nervous system of Xenopus laevis. Int. J. Dev. Biol 38, 623-632.[Medline]

Favor, J., Sandulache, R., Neuhauser-Klaus, A., Pretsch, W., Chatterjee, B., Senft, E., Wurst, W., Blanquet, V., Grimes, P., Sporle, R. and Schughart, K (1996). The mouse Pax2(1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney. Proc. Natl. Acad. Sci. USA 93, 13870-13875.[Abstract/Free Full Text]

Feldman, B., Poueymirou, W., Papaioannou, V. E., DeChiara, T. M. and Goldfarb, M (1995). Requirement of FGF-4 for postimplantation mouse development. Science 267, 246-249.[Abstract/Free Full Text]

Friedman, G. C. and O'Leary, D. D (1996). Retroviral misexpression of engrailed genes in the chick optic tectum perturbs the topographic targeting of retinal axons. J. Neurosci 16, 5498-5509.[Abstract/Free Full Text]

Fritzsch, B., Nichols, D. H., Echelard, Y. and McMahon, A. P (1995). Development of midbrain and anterior hindbrain ocular motoneurons in normal and Wnt-1 knockout mice. J. Neurobiol 27, 457-469.[Medline]

Gardner, C. A., Darnell, D. K., Poole, S. J., Ordahl, C. P. and Barald, K. F (1988). Expression of an engrailed-like gene during development of the early embryonic chick nervous system. J. Neurosci. Res 21, 426-437.[Medline]

Gardner, C. A. and Barald, K. F (1991). The cellular environment controlsthe expression of engrailed -like protein in the cranial neuroepithelium of quail-chcik chimeric embryos. Development 113, 1037-1048.[Abstract]

Gardner, C. A. and Barald, K. F (1992). Expression patterns of engrailed-like proteins in the chick embryo. Dev. Dyn 193, 370-388.[Medline]

Hallonet, M. E. R., Teillet, M. A. and LeDouarin, N. M (1990). A new approach to the development of the cerebellum provided by the quail-chick marker system. Development 108, 19-31.[Abstract]

Hallonet, M. E. R. and LeDouarin, N. M (1993). Tracing neuroepithelial cells of the mesencephalic and metencephalic alar plates during cerebellar ontogeny in quail-chick chimeras. Eur. J. Neurosci 5, 1145-1155.[Medline]

Hamburger, V. and Hamilton, H (1951). A series of normal stages in the development of the chick embryo. J. Morphol 88, 49-92.

Hanks, M., Wurst, W., Anson-Cartwright, L., Auerbach, A. B. and Joyner, A. L (1995). Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 269, 679-682.[Abstract/Free Full Text]

Hatta, K., Bremiller, R., Westerfield, M. and Kimmel, C. B (1991). Diversity of expression of engrailed-like antigens in zebrafish. Development 112, 821-832.[Abstract]

Heikinheimo, M., Lawshe, A., Shackleford, G. M., Wilson, D. B. and MacArthur, C. A (1994). Fgf-8 expression in the post-gastrulation mouse suggests roles in the development of the face, limbs and central nervous system. Mech. Dev 48, 129-138.[Medline]

Heller, N. and Brandli, A. W (1997). Xenopus Pax-2 displays multiple splice forms during embryogenesis and pronephric kidney development. Mech. Dev 69, 83-104.[Medline]

Hemmati-Brivanlou, A. and Harland, R. M (1989). Expression of an engrailed-related protein is induced in the anterior neural ectoderm of early Xenopus embryos. Development 106, 611-7.[Abstract]

Hemmati-Brivanlou, A., Stewart, R. M. and Harland, R. M (1990). Region-specific neural induction of an engrailed protein by anterior notochord in Xenopus. Science 250, 800-802.[Abstract/Free Full Text]

Hollyday, M., McMahon, J. A. and McMahon, A. P (1995). Wnt expression patterns in chick embryo nervous system. Mech Dev 52, 9-25.[Medline]

Ichijo, H., Fujita, S., Matsuno, T. and Nakamura, H (1990). Rotation of the tectal primordium reveals plasticity of target recognition in retinotectal projection. Development 110, 331-342.[Abstract/Free Full Text]

Isaacs, H. V., Tannahill, D. and Slack, J. M (1992). Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification. Development 114, 711-20.[Abstract]

Itasaki, N., Ichijo, H., Hama, C., Matsuno, T. and Nakamura, H (1991). Establishment of rostrocaudal polarity in tectal primordium: engrailed expression and subsequent tectal polarity. Development 113, 1133-44.[Abstract]

Itasaki, N. and Nakamura, H (1996). A role for gradient en expression in positional specification on the optic tectum. Neuron 16, 55-62.[Medline]

Joyner, A. L., Herrup, K., Auerbach, B. A., Davis, C. A. and Rossant, J (1991). Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox. Science 251, 1239-1243.[Abstract/Free Full Text]

Joyner, A. L (1996). Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development. Trends Genet 12, 15-20.[Medline]

Kelly, G. M. and Moon, R. T (1995). Involvement of wnt1 and pax2 in the formation of the midbrain-hindbrain boundary in the zebrafish gastrula. Dev. Genet 17, 129-140.[Medline]

Krauss, S., Maden, M., Holder, N. and Wilson, S. W (1992). Zebrafish pax[b] is involved in the formation of the midbrain-hindbrain boundary. Nature 360, 87-89.[Medline]

Kuemerle, B., Zanjani, H., Joyner, A. and Herrup, K (1997). Pattern deformities and cell loss in Engrailed-2 mutant mice suggest two separate patterning events during cerebellar development. J. Neurosci 17, 7881-7889.[Abstract/Free Full Text]

Lee, S. M., Danielian, P. S., Fritzsch, B. and McMahon, A. P (1997). Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development 124, 959-969.[Abstract]

Logan, C., Wizenmann, A., Drescher, U., Monschau, B., Bonhoeffer, F. and Lumsden, A (1996). Rostral optic tectum acquires caudal characteristics following ectopic engrailed expression. Curr. Biol 6, 1006-1014.[Medline]

Lumsden, A. G. S. and Davies, A. M (1983). Earliest sensory nerve fibres are guided to peripheral targets by attractants other than nerve growth factor. Nature 306, 786-788.[Medline]

MacArthur, C. A., Lawshe, A., Xu, J., Santos-Ocampo, S., Heikinheimo, M., Chellaiah, A. T. and Ornitz, D. M (1995). FGF-8 isoforms activate receptor splice forms that are expressed in mesenchymal regions of mouse development. Development 121, 3603-3613.[Abstract]

Mahmood, R., Bresnick, J., Hornbruch, A., Mahony, K., Morton, N.,Colquhoun, K., Martin, P., Lumsden, A., Dickson, C. and Mason, I (1995). FGF-8 in the mouse embryo: a role in the initiation and maintenance of limb bud outgrowth. Curr. Biol 5, 797-806.[Medline]

Mahmood, R., Mason, I. J. and Morriss-Kay, G. M (1996). Expression of Fgf-3 in relation to hindbrain segmentation, otic pit position and pharyngeal arch morphology in normal and retinoic acid-exposed mouse embryos. Anat. Embryol. (Berl) 194, 13-22.[Medline]

Marin, F. and Puelles, L (1994). Patterning of the embryonic midbrain after experimental inversions: a polarizing activity from the isthmus. Dev. Biol 163, 19-37.[Medline]

Martinez, S. and Alvarado-Mallart, R. M (1989). Rostral cerebellum originates from the caudal portion of the so-called \324mesencephalic' vesicle: a study using chick/quail chimeras. Eur. J. Neurosci 1, 549-560.[Medline]

Martinez, S. and Alvarado-Mallart, R.-M (1990). Expression of the homeobox gene Chick-en in chick/quail chimeras with inverted mes-metencephalic grafts. Dev. Biol 139, 432-436.[Medline]

Martinez, S., Wassef, M. and Alvarado-Mallart, R.-M (1991). Induction of a mesencephalic phenotype in the 2-day-old chick prosencephalon is preceded by the early expression of the homeobox gene en. Neuron 6, 971-981.[Medline]

Mason, I (1996). Neural induction: do FGFs strike a cord?. Curr. Biol 6, 672-675.[Medline]

McMahon, A. P. and Bradley, A (1990). The wnt-1 ( int-1 ) proto-oncogene is required for development of a large region of the mouse brain. Cell 62, 1073-1085.[Medline]

McMahon, A. P., Joyner, A. L., Bradley, A. and McMahon, J. A (1992). The midbrain-hindbrain phenotype of wnt1 /wnt1 mice results from stepwise deletion of engrailed -expressing cells by 9.5 days postcoitum.. Cell 69, 581-595.[Medline]

Meyers, E. N., Lewandoski, M. and Martin, G. R (1998). An Fgf8 mutant allelic series generated by Cre-and Flp-mediated recombination. Nat. Genet 18, 136-141.[Medline]

Millen, K. J., Wurst, W., Herrup, K. and Joyner, A. L (1994). Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants. Development 120, 695-706.[Abstract]

Millen, K. J., Hui, C. C. and Joyner, A. L (1995). A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum. Development 121, 3935-3945.[Abstract]

Millet, S. and Alvarado-Mallart, R. M (1995). Expression of the homeobox-containing gene En-2 during the development of the chick central nervous system. Eur. J. Neurosci 7, 777-791.[Medline]

Millet, S., Bloch-Gallego, E., Simeone, A. and Alvarado-Mallart, R. M (1996). The caudal limit of Otx2 gene expression as a marker of the midbrain/hindbrain boundary: a study using in situ hybridisation and chick/quail homotopic grafts. Development 122, 3785-3797.[Abstract]

Muhr, J., Jessell, T. M. and Edlund, T (1997). Assignment of early caudal identity to neural plate cells by a signal from caudal paraxial mesoderm. Neuron 19, 487-502.[Medline]

Nakamura, H., Nakano, K. E., Igawa, H. H., Takagi, S. and Fujisawa, H (1986). Plasticity and rigidity of differentiation of brain vesicles studied in quail-chick chimeras. Cell Diff 19, 187-193.[Medline]

Nakamura, H., Takagi, S., Tsuji, T., Matsui, K. A. and Fujisawa, H (1988). The prosencephalon has the capacity to differentiate into the optic tectum: analysis in quail-chick-chimeric brains. Dev. Growth Diff 30, 717-725.

Nakamura, H (1990). Do CNS anlagen have plasticity in differentiation? Analysis in quail-chick chimera. Brain Res 511, 122-128.[Medline]

Niswander, L., Jeffrey, S., Martin, G. R. and Tickle, C (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.[Medline]

Ohuchi, H., Yoshioka, H., Tanaka, A., Kawakami, Y., Nohno, T. and Noji, S (1994). Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis. Biochem. Biophys. Res. Commun 204, 882-888.[Medline]

Parr, B. A., Shea, M. J., Vassileva, G. and McMahon, A. P (1993). Mouse wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 119, 247-261.[Abstract]

Puschel, A. W., Westerfield, M. and Dressler, G. R (1992). Comparative analysis of Pax-2 protein distributions during neurulation in mice and zebrafish. Mech Dev 38, 197-208.[Medline]

Riefers, F., Bohli, H., Walsh, E., Crossley, P., Stanier, D. and Brand, M (1998). Fgf8 is mutated in zebrafish acerebellar ( ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125, 2381-2395.[Abstract]

Rhinn, M., Dierich, A., Shawlot, W., Behringer, R. R., Le Meur, M. and Ang, S. L (1998). Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification. Development 125, 845-856.[Abstract]

Roberts, C., Platt, N., Streit, A., Schachner, M. and Stern, C. D (1991). The L5 epitope: an early marker for neural induction in the chick embryo and its involvement in inductive interactions. Development 112, 959-970.[Abstract]

Rowitch, D. H. and McMahon, A. P (1995). Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mech Dev 52, 3-8.[Medline]

Ruiz i Altaba, A (1994). Pattern formation in the vertebrate neural plate. Trends Neurosci 17, 233-243.[Medline]

Ruiz i Altaba, A (1998). Neural patterning. Deconstructing the organizer. Nature 391, 748-749.[Medline]

Schoenwolf, G. C. and Sheard, P (1990). Fate mapping the avian epiblast with focal injections of a fluorescent-histochemical marker: ectodermal derivatives. J. Exp. Zool 255, 323-339.[Medline]

Schwarz, M., Alvarez-Bolado, G., Urbanek, P., Busslinger, M. and Gruss, P (1997). Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations. Proc. Natl. Acad. Sci. USA 94, 14518-1423.[Abstract/Free Full Text]

Shamim, H. and Mason, I (1998). Expression of Gbx-2 during early development of the chick embryo. Mech. Dev 76, 157-159.[Medline]

Storey, K. G., Goriely, A., Sargent, C. M., Brown, J. M., Burns, H. D., Abud, H. M. and Heath, J. K (1998). Early posterior neural tissue is induced by FGF in the chick embryo. Development 125, 473-484.[Abstract]

Thomas, K. R. and Capecchi, M. R (1990). Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346, 847-850.[Medline]

Thomas, K. R., Musci, T. S., Neumann, P. E. and Capecchi, M. R (1991). Swaying is a mutant allele of the proto-oncogene wnt-1. Cell 67, 969-976.[Medline]

Urbanek, P., Fetka, I., Meisler, M. H. and Busslinger, M (1997). Cooperation of Pax2 and Pax5 in midbrain and cerebellum development. Proc. Natl. Acad. Sci. USA 94, 5703-5708.[Abstract/Free Full Text]

Urbanek, P., Wang, Z. Q., Fetka, I., Wagner, E. F. and Busslinger, M (1994). Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 79, 901-912.[Medline]

Vogel, A., Rodriguez, C. and Izpisua-Belmonte, J. C (1996). Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development 122, 1737-1750.[Abstract]

Wassarman, K. M., Lewandoski, M., Campbell, K., Joyner, A. L., Rubenstein, J. L., Martinez, S. and Martin, G. R (1997). Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development 124, 2923-2934.[Abstract]

Wassef, M. and Joyner, A. L (1997). Early mesencephalon/metencephalon patterning and development of the cerebellum. Perspect. Dev. Neurobiol 5, 3-16.[Medline]

Wilkinson, D. G., Bailes, J. A. and McMahon, A. P (1987). Expression of the proto-oncogene wnt-1 is restricted to specific neural cells in the developing mouse embryo. Cell 50, 79-88.[Medline]

Williams, E. J., Furness, J., Walsh, F. S. and Doherty, P (1994). Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin. Neuron 13, 583-594.[Medline]

Wurst, W., Auerbach, A. B. and Joyner, A. L (1994). Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development 120, 2065-2075.[Abstract]

Yamaguchi, T., Harpal, K., Henkemeyer, M. and Rossant, J (1994). fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev 8, 3032-3044.[Abstract/Free Full Text]

Ye, W., Shimamura, K., Rubenstein, J. R., Hynes, M. A. and Rosenthal, A (1998). FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell 93, 755-766.[Medline]

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The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum
Development, June 15, 2003; 130(12): 2633 - 2644.
[Abstract] [Full Text] [PDF]

E. Matsunaga, T. Katahira, and H. Nakamura
Role of Lmx1b and Wnt1 in mesencephalon and metencephalon development
Development, March 13, 2003; 129(22): 5269 - 5277.
[Abstract] [Full Text] [PDF]

C. Irving, A. Malhas, S. Guthrie, and I. Mason
Establishing the trochlear motor axon trajectory: role of the isthmic organiser and Fgf8
Development, January 12, 2002; 129(23): 5389 - 5398.
[Abstract] [Full Text] [PDF]

A. Glavic, J. L. Gomez-Skarmeta, and R. Mayor
The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation
Development, January 4, 2002; 129(7): 1609 - 1621.
[Abstract] [Full Text] [PDF]

D. Kobayashi, M. Kobayashi, K. Matsumoto, T. Ogura, M. Nakafuku, and K. Shimamura
Early subdivisions in the neural plate define distinct competence for inductive signals
Development, January 1, 2002; 129(1): 83 - 93.
[Abstract] [Full Text] [PDF]

J. Y. H. Li and A. L. Joyner
Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression
Development, December 15, 2001; 128(24): 4979 - 4991.
[Abstract] [Full Text] [PDF]

J. P. Martinez-Barbera, M. Signore, P. P. Boyl, E. Puelles, D. Acampora, R. Gogoi, F. Schubert, A. Lumsden, and A. Simeone
Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2
Development, December 1, 2001; 128(23): 4789 - 4800.
[Abstract] [Full Text] [PDF]

H.-G. Belting, G. Hauptmann, D. Meyer, S. Abdelilah-Seyfried, A. Chitnis, C. Eschbach, I. Soll, C. Thisse, B. Thisse, K. B. Artinger, et al.
spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer
Development, November 1, 2001; 128(21): 4165 - 4176.
[Abstract] [Full Text] [PDF]

E. Matsunaga, I. Araki, and H. Nakamura
Role of Pax3/7 in the tectum regionalization
Development, October 15, 2001; 128(20): 4069 - 4077.
[Abstract] [Full Text] [PDF]

R. A. Schneider, D. Hu, J. L. R. Rubenstein, M. Maden, and J. A. Helms
Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH
Development, July 15, 2001; 128(14): 2755 - 2767.
[Abstract] [Full Text] [PDF]

T. Sato, I. Araki, and H. Nakamura
Inductive signal and tissue responsiveness defining the tectum and the cerebellum
Development, July 1, 2001; 128(13): 2461 - 2469.
[Abstract] [Full Text] [PDF]

A Liu and A. Joyner
EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region
Development, January 1, 2001; 128(2): 181 - 191.
[Abstract] [PDF]

L. Studer, M. Csete, S.-H. Lee, N. Kabbani, J. Walikonis, B. Wold, and R. McKay
Enhanced Proliferation, Survival, and Dopaminergic Differentiation of CNS Precursors in Lowered Oxygen
J. Neurosci., October 1, 2000; 20(19): 7377 - 7383.
[Abstract] [Full Text] [PDF]

H.-D. Beer, L. Vindevoghel, M. J. Gait, J.-M. Revest, D. R. Duan, I. Mason, C. Dickson, and S. Werner
Fibroblast Growth Factor (FGF) Receptor 1-IIIb Is a Naturally Occurring Functional Receptor for FGFs That Is Preferentially Expressed in the Skin and the Brain
J. Biol. Chem., May 19, 2000; 275(21): 16091 - 16097.
[Abstract] [Full Text] [PDF]

N Bertrand, F Medevielle, and F Pituello
FGF signalling controls the timing of Pax6 activation in the neural tube
Development, January 11, 2000; 127(22): 4837 - 4843.
[Abstract] [PDF]

F Marin and P Charnay
Hindbrain patterning: FGFs regulate Krox20 and mafB/kr expression in the otic/preotic region
Development, January 11, 2000; 127(22): 4925 - 4935.
[Abstract] [PDF]

A Louvi and M Wassef
Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding
Development, January 9, 2000; 127(18): 4061 - 4071.
[Abstract] [PDF]

E Matsunaga, I Araki, and H Nakamura
Pax6 defines the di-mesencephalic boundary by repressing En1 and Pax2
Development, January 6, 2000; 127(11): 2357 - 2365.
[Abstract] [PDF]

J Xu, Z Liu, and D. Ornitz
Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures
Development, January 5, 2000; 127(9): 1833 - 1843.
[Abstract] [PDF]

K. Adams, J. Maida, J. Golden, and R. Riddle
The transcription factor Lmx1b maintains Wnt1 expression within the isthmic organizer
Development, January 5, 2000; 127(9): 1857 - 1867.
[Abstract] [PDF]

Y Watanabe and H Nakamura
Control of chick tectum territory along dorsoventral axis by Sonic hedgehog
Development, January 3, 2000; 127(5): 1131 - 1140.
[Abstract] [PDF]

L Mathis and J. Nicolas
Different clonal dispersion in the rostral and caudal mouse central nervous system
Development, January 3, 2000; 127(6): 1277 - 1290.
[Abstract] [PDF]

C Irving and I Mason
Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression
Development, January 1, 2000; 127(1): 177 - 186.
[Abstract] [PDF]

M Carl and J Wittbrodt
Graded interference with FGF signalling reveals its dorsoventral asymmetry at the mid-hindbrain boundary
Development, January 12, 1999; 126(24): 5659 - 5667.
[Abstract] [PDF]

A Liu, K Losos, and A. Joyner
FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate
Development, January 11, 1999; 126(21): 4827 - 4838.
[Abstract] [PDF]

I Araki and H Nakamura
Engrailed defines the position of dorsal di-mesencephalic boundary by repressing diencephalic fate
Development, January 11, 1999; 126(22): 5127 - 5135.
[Abstract] [PDF]

C Irving and I Mason
Regeneration of isthmic tissue is the result of a specific and direct interaction between rhombomere 1 and midbrain
Development, January 9, 1999; 126(18): 3981 - 3989.
[Abstract] [PDF]

A. Rowan, C. Stern, and K. Storey
Axial mesendoderm refines rostrocaudal pattern in the chick nervous system
Development, January 7, 1999; 126(13): 2921 - 2934.
[Abstract] [PDF]

A Picker, C Brennan, F Reifers, J. Clarke, N Holder, and M Brand
Requirement for the zebrafish mid-hindbrain boundary in midbrain polarisation, mapping and confinement of the retinotectal projection
Development, January 7, 1999; 126(13): 2967 - 2978.
[Abstract] [PDF]

M Hidalgo-Sanchez, A Simeone, and R. Alvarado-Mallart
Fgf8 and Gbx2 induction concomitant with Otx2 repression is correlated with midbrain-hindbrain fate of caudal prosencephalon
Development, January 6, 1999; 126(14): 3191 - 3203.
[Abstract] [PDF]

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				E. Matsunaga, T. Katahira, and H. Nakamura Role of Lmx1b and Wnt1 in mesencephalon and metencephalon development Development, March 13, 2003; 129(22): 5269 - 5277. [Abstract] [Full Text] [PDF]

				C. Irving, A. Malhas, S. Guthrie, and I. Mason Establishing the trochlear motor axon trajectory: role of the isthmic organiser and Fgf8 Development, January 12, 2002; 129(23): 5389 - 5398. [Abstract] [Full Text] [PDF]

				A. Glavic, J. L. Gomez-Skarmeta, and R. Mayor The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation Development, January 4, 2002; 129(7): 1609 - 1621. [Abstract] [Full Text] [PDF]

				D. Kobayashi, M. Kobayashi, K. Matsumoto, T. Ogura, M. Nakafuku, and K. Shimamura Early subdivisions in the neural plate define distinct competence for inductive signals Development, January 1, 2002; 129(1): 83 - 93. [Abstract] [Full Text] [PDF]

				J. Y. H. Li and A. L. Joyner Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression Development, December 15, 2001; 128(24): 4979 - 4991. [Abstract] [Full Text] [PDF]

				J. P. Martinez-Barbera, M. Signore, P. P. Boyl, E. Puelles, D. Acampora, R. Gogoi, F. Schubert, A. Lumsden, and A. Simeone Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2 Development, December 1, 2001; 128(23): 4789 - 4800. [Abstract] [Full Text] [PDF]

				H.-G. Belting, G. Hauptmann, D. Meyer, S. Abdelilah-Seyfried, A. Chitnis, C. Eschbach, I. Soll, C. Thisse, B. Thisse, K. B. Artinger, et al. spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer Development, November 1, 2001; 128(21): 4165 - 4176. [Abstract] [Full Text] [PDF]

				E. Matsunaga, I. Araki, and H. Nakamura Role of Pax3/7 in the tectum regionalization Development, October 15, 2001; 128(20): 4069 - 4077. [Abstract] [Full Text] [PDF]

				R. A. Schneider, D. Hu, J. L. R. Rubenstein, M. Maden, and J. A. Helms Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH Development, July 15, 2001; 128(14): 2755 - 2767. [Abstract] [Full Text] [PDF]

				T. Sato, I. Araki, and H. Nakamura Inductive signal and tissue responsiveness defining the tectum and the cerebellum Development, July 1, 2001; 128(13): 2461 - 2469. [Abstract] [Full Text] [PDF]

				A Liu and A. Joyner EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region Development, January 1, 2001; 128(2): 181 - 191. [Abstract] [PDF]

				L. Studer, M. Csete, S.-H. Lee, N. Kabbani, J. Walikonis, B. Wold, and R. McKay Enhanced Proliferation, Survival, and Dopaminergic Differentiation of CNS Precursors in Lowered Oxygen J. Neurosci., October 1, 2000; 20(19): 7377 - 7383. [Abstract] [Full Text] [PDF]

				H.-D. Beer, L. Vindevoghel, M. J. Gait, J.-M. Revest, D. R. Duan, I. Mason, C. Dickson, and S. Werner Fibroblast Growth Factor (FGF) Receptor 1-IIIb Is a Naturally Occurring Functional Receptor for FGFs That Is Preferentially Expressed in the Skin and the Brain J. Biol. Chem., May 19, 2000; 275(21): 16091 - 16097. [Abstract] [Full Text] [PDF]

				N Bertrand, F Medevielle, and F Pituello FGF signalling controls the timing of Pax6 activation in the neural tube Development, January 11, 2000; 127(22): 4837 - 4843. [Abstract] [PDF]