Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain

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The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation
Development, January 4, 2002; 129(7): 1609 - 1621.
[Abstract] [Full Text] [PDF]

D. Kobayashi, M. Kobayashi, K. Matsumoto, T. Ogura, M. Nakafuku, and K. Shimamura
Early subdivisions in the neural plate define distinct competence for inductive signals
Development, January 1, 2002; 129(1): 83 - 93.
[Abstract] [Full Text] [PDF]

J. Y. H. Li and A. L. Joyner
Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression
Development, December 15, 2001; 128(24): 4979 - 4991.
[Abstract] [Full Text] [PDF]

J. P. Martinez-Barbera, M. Signore, P. P. Boyl, E. Puelles, D. Acampora, R. Gogoi, F. Schubert, A. Lumsden, and A. Simeone
Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2
Development, December 1, 2001; 128(23): 4789 - 4800.
[Abstract] [Full Text] [PDF]

H.-G. Belting, G. Hauptmann, D. Meyer, S. Abdelilah-Seyfried, A. Chitnis, C. Eschbach, I. Soll, C. Thisse, B. Thisse, K. B. Artinger, et al.
spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer
Development, November 1, 2001; 128(21): 4165 - 4176.
[Abstract] [Full Text] [PDF]

E. Matsunaga, I. Araki, and H. Nakamura
Role of Pax3/7 in the tectum regionalization
Development, October 15, 2001; 128(20): 4069 - 4077.
[Abstract] [Full Text] [PDF]

R. A. Schneider, D. Hu, J. L. R. Rubenstein, M. Maden, and J. A. Helms
Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH
Development, July 15, 2001; 128(14): 2755 - 2767.
[Abstract] [Full Text] [PDF]

T. Sato, I. Araki, and H. Nakamura
Inductive signal and tissue responsiveness defining the tectum and the cerebellum
Development, July 1, 2001; 128(13): 2461 - 2469.
[Abstract] [Full Text] [PDF]

A Liu and A. Joyner
EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region
Development, January 1, 2001; 128(2): 181 - 191.
[Abstract] [PDF]

L. Studer, M. Csete, S.-H. Lee, N. Kabbani, J. Walikonis, B. Wold, and R. McKay
Enhanced Proliferation, Survival, and Dopaminergic Differentiation of CNS Precursors in Lowered Oxygen
J. Neurosci., October 1, 2000; 20(19): 7377 - 7383.
[Abstract] [Full Text] [PDF]

H.-D. Beer, L. Vindevoghel, M. J. Gait, J.-M. Revest, D. R. Duan, I. Mason, C. Dickson, and S. Werner
Fibroblast Growth Factor (FGF) Receptor 1-IIIb Is a Naturally Occurring Functional Receptor for FGFs That Is Preferentially Expressed in the Skin and the Brain
J. Biol. Chem., May 19, 2000; 275(21): 16091 - 16097.
[Abstract] [Full Text] [PDF]

N Bertrand, F Medevielle, and F Pituello
FGF signalling controls the timing of Pax6 activation in the neural tube
Development, January 11, 2000; 127(22): 4837 - 4843.
[Abstract] [PDF]

F Marin and P Charnay
Hindbrain patterning: FGFs regulate Krox20 and mafB/kr expression in the otic/preotic region
Development, January 11, 2000; 127(22): 4925 - 4935.
[Abstract] [PDF]

A Louvi and M Wassef
Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding
Development, January 9, 2000; 127(18): 4061 - 4071.
[Abstract] [PDF]

E Matsunaga, I Araki, and H Nakamura
Pax6 defines the di-mesencephalic boundary by repressing En1 and Pax2
Development, January 6, 2000; 127(11): 2357 - 2365.
[Abstract] [PDF]

J Xu, Z Liu, and D. Ornitz
Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures
Development, January 5, 2000; 127(9): 1833 - 1843.
[Abstract] [PDF]

K. Adams, J. Maida, J. Golden, and R. Riddle
The transcription factor Lmx1b maintains Wnt1 expression within the isthmic organizer
Development, January 5, 2000; 127(9): 1857 - 1867.
[Abstract] [PDF]

Y Watanabe and H Nakamura
Control of chick tectum territory along dorsoventral axis by Sonic hedgehog
Development, January 3, 2000; 127(5): 1131 - 1140.
[Abstract] [PDF]

L Mathis and J. Nicolas
Different clonal dispersion in the rostral and caudal mouse central nervous system
Development, January 3, 2000; 127(6): 1277 - 1290.
[Abstract] [PDF]

C Irving and I Mason
Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression
Development, January 1, 2000; 127(1): 177 - 186.
[Abstract] [PDF]

M Carl and J Wittbrodt
Graded interference with FGF signalling reveals its dorsoventral asymmetry at the mid-hindbrain boundary
Development, January 12, 1999; 126(24): 5659 - 5667.
[Abstract] [PDF]

A Liu, K Losos, and A. Joyner
FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate
Development, January 11, 1999; 126(21): 4827 - 4838.
[Abstract] [PDF]

I Araki and H Nakamura
Engrailed defines the position of dorsal di-mesencephalic boundary by repressing diencephalic fate
Development, January 11, 1999; 126(22): 5127 - 5135.
[Abstract] [PDF]

C Irving and I Mason
Regeneration of isthmic tissue is the result of a specific and direct interaction between rhombomere 1 and midbrain
Development, January 9, 1999; 126(18): 3981 - 3989.
[Abstract] [PDF]

A. Rowan, C. Stern, and K. Storey
Axial mesendoderm refines rostrocaudal pattern in the chick nervous system
Development, January 7, 1999; 126(13): 2921 - 2934.
[Abstract] [PDF]

A Picker, C Brennan, F Reifers, J. Clarke, N Holder, and M Brand
Requirement for the zebrafish mid-hindbrain boundary in midbrain polarisation, mapping and confinement of the retinotectal projection
Development, January 7, 1999; 126(13): 2967 - 2978.
[Abstract] [PDF]

				M. A. Basson, D. Echevarria, C. Petersen Ahn, A. Sudarov, A. L. Joyner, I. J. Mason, S. Martinez, and G. R. Martin Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development Development, March 1, 2008; 135(5): 889 - 898. [Abstract] [Full Text] [PDF]

				S. Shim, Y. Kim, J. Shin, J. Kim, and S. Park Regulation of EphA8 Gene Expression by TALE Homeobox Transcription Factors during Development of the Mesencephalon Mol. Cell. Biol., March 1, 2007; 27(5): 1614 - 1630. [Abstract] [Full Text] [PDF]

				N. Kosaka, M. Kodama, H. Sasaki, Y. Yamamoto, F. Takeshita, Y. Takahama, H. Sakamoto, T. Kato, M. Terada, and T. Ochiya FGF-4 regulates neural progenitor cell proliferation and neuronal differentiation FASEB J, July 1, 2006; 20(9): 1484 - 1485. [Abstract] [Full Text] [PDF]

				S. T. Waters and M. Lewandoski A threshold requirement for Gbx2 levels in hindbrain development. Development, May 1, 2006; 133(10): 1991 - 2000. [Abstract] [Full Text] [PDF]

				F. P. O'Hara, E. Beck, L. K. Barr, L. L. Wong, D. S. Kessler, and R. D. Riddle Zebrafish Lmx1b.1 and Lmx1b.2 are required for maintenance of the isthmic organizer Development, July 15, 2005; 132(14): 3163 - 3173. [Abstract] [Full Text] [PDF]

				J. Y. H. Li, Z. Lao, and A. L. Joyner New regulatory interactions and cellular responses in the isthmic organizer region revealed by altering Gbx2 expression Development, April 15, 2005; 132(8): 1971 - 1981. [Abstract] [Full Text] [PDF]

				M. Rhinn, K. Lun, M. Luz, M. Werner, and M. Brand Positioning of the midbrain-hindbrain boundary organizer through global posteriorization of the neuroectoderm mediated by Wnt8 signaling Development, March 15, 2005; 132(6): 1261 - 1272. [Abstract] [Full Text] [PDF]

				T. Sato and H. Nakamura The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway Development, September 1, 2004; 131(17): 4275 - 4285. [Abstract] [Full Text] [PDF]

				M. P. Smidt, S. M. Smits, H. Bouwmeester, F. P. T. Hamers, A. J. A. van der Linden, A. J. C. G. M. Hellemons, J. Graw, and J. P. H. Burbach Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3 Development, March 1, 2004; 131(5): 1145 - 1155. [Abstract] [Full Text] [PDF]

				J. Jaszai, F. Reifers, A. Picker, T. Langenberg, and M. Brand Isthmus-to-midbrain transformation in the absence of midbrain-hindbrain organizer activity Development, December 29, 2003; 130(26): 6611 - 6623. [Abstract] [Full Text] [PDF]

				Y. Alvarez, M. T. Alonso, V. Vendrell, L. C. Zelarayan, P. Chamero, T. Theil, M. R. Bosl, S. Kato, M. Maconochie, D. Riethmacher, et al. Requirements for FGF3 and FGF10 during inner ear formation Development, December 22, 2003; 130(25): 6329 - 6338. [Abstract] [Full Text] [PDF]

				P. Alexandre and M. Wassef The isthmic organizer links anteroposterior and dorsoventral patterning in the mid/hindbrain by generating roof plate structures Development, November 15, 2003; 130(22): 5331 - 5338. [Abstract] [Full Text] [PDF]

				J. Walshe and I. Mason Unique and combinatorial functions of Fgf3 and Fgf8 during zebrafish forebrain development Development, September 15, 2003; 130(18): 4337 - 4349. [Abstract] [Full Text] [PDF]

				C. L. Chi, S. Martinez, W. Wurst, and G. R. Martin The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum Development, June 15, 2003; 130(12): 2633 - 2644. [Abstract] [Full Text] [PDF]

				E. Matsunaga, T. Katahira, and H. Nakamura Role of Lmx1b and Wnt1 in mesencephalon and metencephalon development Development, March 13, 2003; 129(22): 5269 - 5277. [Abstract] [Full Text] [PDF]

				C. Irving, A. Malhas, S. Guthrie, and I. Mason Establishing the trochlear motor axon trajectory: role of the isthmic organiser and Fgf8 Development, January 12, 2002; 129(23): 5389 - 5398. [Abstract] [Full Text] [PDF]

				A. Glavic, J. L. Gomez-Skarmeta, and R. Mayor The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation Development, January 4, 2002; 129(7): 1609 - 1621. [Abstract] [Full Text] [PDF]

				D. Kobayashi, M. Kobayashi, K. Matsumoto, T. Ogura, M. Nakafuku, and K. Shimamura Early subdivisions in the neural plate define distinct competence for inductive signals Development, January 1, 2002; 129(1): 83 - 93. [Abstract] [Full Text] [PDF]

				J. Y. H. Li and A. L. Joyner Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression Development, December 15, 2001; 128(24): 4979 - 4991. [Abstract] [Full Text] [PDF]

				J. P. Martinez-Barbera, M. Signore, P. P. Boyl, E. Puelles, D. Acampora, R. Gogoi, F. Schubert, A. Lumsden, and A. Simeone Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2 Development, December 1, 2001; 128(23): 4789 - 4800. [Abstract] [Full Text] [PDF]

				H.-G. Belting, G. Hauptmann, D. Meyer, S. Abdelilah-Seyfried, A. Chitnis, C. Eschbach, I. Soll, C. Thisse, B. Thisse, K. B. Artinger, et al. spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer Development, November 1, 2001; 128(21): 4165 - 4176. [Abstract] [Full Text] [PDF]

				E. Matsunaga, I. Araki, and H. Nakamura Role of Pax3/7 in the tectum regionalization Development, October 15, 2001; 128(20): 4069 - 4077. [Abstract] [Full Text] [PDF]

				R. A. Schneider, D. Hu, J. L. R. Rubenstein, M. Maden, and J. A. Helms Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH Development, July 15, 2001; 128(14): 2755 - 2767. [Abstract] [Full Text] [PDF]

				T. Sato, I. Araki, and H. Nakamura Inductive signal and tissue responsiveness defining the tectum and the cerebellum Development, July 1, 2001; 128(13): 2461 - 2469. [Abstract] [Full Text] [PDF]

				A Liu and A. Joyner EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region Development, January 1, 2001; 128(2): 181 - 191. [Abstract] [PDF]

				L. Studer, M. Csete, S.-H. Lee, N. Kabbani, J. Walikonis, B. Wold, and R. McKay Enhanced Proliferation, Survival, and Dopaminergic Differentiation of CNS Precursors in Lowered Oxygen J. Neurosci., October 1, 2000; 20(19): 7377 - 7383. [Abstract] [Full Text] [PDF]

				H.-D. Beer, L. Vindevoghel, M. J. Gait, J.-M. Revest, D. R. Duan, I. Mason, C. Dickson, and S. Werner Fibroblast Growth Factor (FGF) Receptor 1-IIIb Is a Naturally Occurring Functional Receptor for FGFs That Is Preferentially Expressed in the Skin and the Brain J. Biol. Chem., May 19, 2000; 275(21): 16091 - 16097. [Abstract] [Full Text] [PDF]

				N Bertrand, F Medevielle, and F Pituello FGF signalling controls the timing of Pax6 activation in the neural tube Development, January 11, 2000; 127(22): 4837 - 4843. [Abstract] [PDF]

				F Marin and P Charnay Hindbrain patterning: FGFs regulate Krox20 and mafB/kr expression in the otic/preotic region Development, January 11, 2000; 127(22): 4925 - 4935. [Abstract] [PDF]

				A Louvi and M Wassef Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding Development, January 9, 2000; 127(18): 4061 - 4071. [Abstract] [PDF]