Dominant effects of RET receptor misexpression and ligand-independent RET signaling on ureteric bud development

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Srinivas, S.
	Articles by Costantini, F.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Srinivas, S.
	Articles by Costantini, F.


Social Bookmarking

	What's this?

Arighi, E., Alberti, L., Torriti, F., Ghizzoni, S., Rizzetti, M. G., Pelicci, G., Pasini, B., Bongarzone, I., Piutti, C., Pierotti, M. A. et al (1997). Identification of Shc docking site on Ret tyrosine kinase. Oncogene 14, 773-782.[Medline]

Asai, N., Iwashita, T., Matsuyama, M. and Takahashi, M (1995). Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations. Mol. Cell. Biol 15, 1613-1619.[Abstract]

Asai, N., Murakami, H., Iwashita, T. and Takahashi, M (1996). A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins. J. Biol. Chem 271, 17644-17649.[Abstract/Free Full Text]

Baloh, R. H., Tansey, M. G., Golden, J. P., Creedon, D. J., Heuckeroth, R. O., Keck, C. L., Zimonjic, D. B., Popescu, N. C., Johnson, E. M., Jr. and Milbrandt, J (1997). TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron 18, 793-802.[Medline]

Bard, J. B., McConnell, J. E. and Davies, J. A (1994). Towards a genetic basis for kidney development. Mech. Dev 48, 3-11.[Medline]

Bongarzone, I., Monzini, N., Borrello, M. G., Carcano, C., Ferraresi, G., Arighi, E., Mondellini, P., Della, P. G. and Pierotti, M. A (1993). Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase A. Mol. Cell. Biol 13, 358-366.[Abstract/Free Full Text]

Borrello, M. G., Pelicci, G., Arighi, E., De Filippis, L., Greco, A., Bongarzone, I., Rizzetti, M., Pelicci, P. G. and Pierotti, M. A (1994). The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb2 adaptor proteins. Oncogene 9, 1661-1668.[Medline]

D'Agati, V. and Trudel, M (1992). Lectin characterization of cystogenesis in the SBM transgenic model of polycystic kidney disease. J. Am. Soc. Nephrol 3, 975-983.[Abstract]

Durbec, P., Marcos-Gutierrez, C. V., Kilkenny, C., Grigoriou, M., Wartiowaara, K., Suvanto, P., Smith, D., Ponder, B., Costantini, F., Saarma, M. et al (1996). GDNF signalling through the Ret receptor tyrosine kinase. Nature 381, 789-793.[Medline]

Durick, K., Yao, V. J., Borrello, M. G., Bongarzone, I., Pierotti, M. A. and Taylor, S. S (1995). Tyrosines outside the kinase core and dimerization are required for the mitogenic activity of RET/ptc2. J. Biol. Chem 270, 24642-24645.[Abstract/Free Full Text]

Duttlinger, R., Manova, K., Berrozpe, G., Chu, T. Y., DeLeon, V., Timokhina, I., Chaganti, R. S., Zelenetz, A. D., Bachvarova, R. F. and Besmer, P (1995). The Wsh and Ph mutations affect the c-kit expression profile: c-kit misexpression in embryogenesis impairs melanogenesis in Wsh and Ph mutant mice. Proc. Natl. Acad. Sci. USA 92, 3754-3758.[Abstract/Free Full Text]

Duttlinger, R., Manova, K., Chu, T. Y., Gyssler, C., Zelenetz, A. D., Bachvarova, R. F. and Besmer, P (1993). W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesis. Development 118, 705-717.[Abstract]

Enomoto, H., Araki, T., Jackman, A., Heuckeroth, R. O., Snider, W. D.,Johnson, E. M. J. and Milbrandt, J (1998). GFR1-deficient mice have deficits in the enteric nervous system and kidneys. Neuron 21, 317-324.[Medline]

Erickson, R. A (1968). Inductive interactions in the development of the mouse metanephros. J. Exp. Zool 169, 33-42.[Medline]

Grobstein, C (1953). Inductive epithelio-mesenchymal interaction in cultured organ rudiments of the mouse. Science 118, 52-55.[Free Full Text]

Grobstein, C (1955). Inductive interaction in the development of the mouse metanephros. J. Exp. Zool 130, 319-340.

Hellmich, H. L., Kos, L., Cho, E. S., Mahon, K. A. and Zimmer, A (1996). Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions. Mech. Dev 54, 95-105.[Medline]

Iwamoto, T., Taniguchi, M., Asai, N., Ohkusu, K., Nakashima, I. and Takahashi, M (1993). cDNA cloning of mouse ret proto-oncogene and its sequence similarity to the cadherin superfamily. Oncogene 8, 1087-1091.[Medline]

Iwashita, T., Asai, N., Murakami, H., Matsuyama, M. and Takahashi, M (1996). Identification of tyrosine residues that are essential for transforming activity of the ret proto-oncogene with MEN2A or MEN2B mutation. Oncogene 12, 481-487.[Medline]

Jing, S., Wen, D., Yu, Y., Holst, P. L., Luo, Y., Fang, M., Tamir, R., Antonio, L., Hu, Z., Cupples, R. et al (1996). GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF. Cell 85, 1113-1124.[Medline]

Kluppel, M., Nagle, D. L., Bucan, M. and Bernstein, A (1997). Long-range genomic rearrangements upstream of Kit dysregulate the developmental pattern of Kit expression in W57 and Wbanded mice and interfere with distinct steps in melanocyte development. Development 124, 65-77.[Abstract]

Kress, C., Vogels, R., De, G. W., Bonnerot, C., Meijlink, F., Nicolas, J. F. and Deschamps, J (1990). Hox-2.3 upstream sequences mediate lacZ expression in intermediate mesoderm derivatives of transgenic mice. Development 109, 775-786.[Abstract/Free Full Text]

Lechner, M. S. and Dressler, G. R (1997). The molecular basis of embryonic kidney development. Mech. Dev 62, 105-120.[Medline]

Lin, L. F., Doherty, D. H., Lile, J. D., Bektesh, S. and Collins, F (1993). GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260, 1130-1132.[Abstract/Free Full Text]

Liu, X., Vega, Q. C., Decker, R. A., Pandey, A., Worby, C. A. and Dixon, J. E (1996). Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities. J. Biol. Chem 271, 5309-5312.[Abstract/Free Full Text]

Lorenzo, M. J., Gish, G. D., Houghton, C., Stonehouse, T. J., Pawson, T., Ponder, B. A. and Smith, D. P (1997). RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2. Oncogene 14, 763-771.[Medline]

Miyamoto, N., Yoshida, M., Kuratani, S., Matsuo, I. and Aizawa, S (1997). Defects of urogenital development in mice lacking Emx2. Development 124, 1653-1664.[Abstract]

Moore, M. W., Klein, R. D., Farinas, I., Sauer, H., Armanini, M., Phillips, H., Reichardt, L. F., Ryan, A. M., Carver-Moore, K. and Rosenthal, A (1996). Renal and neuronal abnormalities in mice lacking GDNF. Nature 382, 76-79.[Medline]

Ohiwa, M., Murakami, H., Iwashita, T., Asai, N., Iwata, Y., Imai, T., Funahashi, H., Takagi, H. and Takahashi, M (1997). Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations. Biochem. Biophys. Res. Commun 237, 747-751.[Medline]

Pachnis, V., Mankoo, B. S. and Costantini, F (1993). Expression of the c-ret proto-oncogene during mouse embryogenesis. Development 119, 1005-1017.[Abstract]

Pepicelli, C. V., Kispert, A., Rowitch, D. H. and McMahon, A. P (1997). GDNF induces branching and increased cell proliferation in the ureter of the mouse. Dev. Biol 192, 193-198.[Medline]

Pichel, J. G., Shen, L., Sheng, H. Z., Granholm, A. C., Drago, J., Grinberg, A., Lee, E. J., Huang, S. P., Saarma, M., Hoffer, B. J. et al (1996). Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382, 73-76.[Medline]

Robertson, K. and Mason, I (1997). The GDNF-RET signalling partnership. Trends Genet 13, 1-3.[Medline]

Rossel, M., Pasini, A., Chappuis, S., Geneste, O., Fournier, L., Schuffenecker, I., Takahashi, M., van Grunsven, L. A., Urdiales, J. L., Rudkin, B. B. et al (1997). Distinct biological properties of two RET isoforms activated by MEN 2A and MEN 2B mutations. Oncogene 14, 265-275.[Medline]

Sainio, K., Suvanto, P., Davies, J., Wartiovaara, J., Wartiovaara, K.,Saarma, M., Arumae, U., Meng, X., Lindahl, M., Pachnis, V. et al (1997). Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development 124, 4077-4087.[Abstract]

Sanchez, M. P., Silos-Santiago, I., Frisen, J., He, B., Lira, S. A. and Barbacid, M (1996). Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382, 70-73.[Medline]

Santoro, M., Carlomagno, F., Romano, A., Bottaro, D. P., Dathan, N. A., Grieco, M., Fusco, A., Vecchio, G., Matoskova, B., Kraus, M. H. et al (1995). Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B. Science 267, 381-383.[Abstract/Free Full Text]

Sariola, H. and Sainio, K (1997). The tip-top branching ureter. Curr. Opin. Cell. Biol 9, 877-884.[Medline]

Saxen, L (1970). Failure to demonstrate tubule induction in a heterologous mesenchyme. Dev. Biol 23, 511-523.[Medline]

Schuchardt, A., D'Agati, V., Larsson-Blomberg, L., Costantini, F. and Pachnis, V (1994). Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367, 380-383.[Medline]

Schuchardt, A., D'Agati, V., Pachnis, V. and Costantini, F (1996). Renal agenesis and hypodysplasia in ret-k-mutant mice result from defects in ureteric bud development. Development 122, 1919-1929.[Abstract]

Schuchardt, A., Srinivas, S., Pachnis, V. and Costantini, F (1995). Isolation and characterization of a chicken homolog of the c-ret proto-oncogene. Oncogene 10, 641-649.[Medline]

Suvanto, P., Hiltunen, J. O., Arumae, U., Moshnyakov, M., Sariola, H., Sainio, K. and Saarma, M (1996). Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization. Eur. J. Neurosci 8, 816-822.[Medline]

Suvanto, P., Wartiovaara, K., Lindahl, M., Arumae, U., Moshnyakov, M., Horelli-Kuitunen, N., Airaksinen, M. S., Palotie, A., Sariola, H. and Saarma, M (1997). Cloning, mRNA distribution and chromosomal localisation of the gene for glial cell line-derived neurotrophic factor receptor beta, a homologue to GDNFR-alpha. Hum. Mol. Genet 6, 1267-1273.[Abstract/Free Full Text]

Tahira, T., Ishizaka, Y., Itoh, F., Sugimura, T. and Nagao, M (1990). Characterization of ret proto-oncogene mRNAs encoding two isoforms of the protein product in a human neuroblastoma cell line. Oncogene 5, 97-102.[Medline]

Takahashi, M., Buma, Y. and Hiai, H (1989). Isolation of ret proto-oncogene cDNA with an amino-terminal signal sequence. Oncogene 4, 805-806.[Medline]

Takahashi, M., Buma, Y., Iwamoto, T., Inaguma, Y., Ikeda, H. and Hiai, H (1988). Cloning and expression of the ret proto-oncogene encoding a tyrosine kinase with two potential transmembrane domains. Oncogene 3, 571-578.[Medline]

Takahashi, M. and Cooper, G. M (1987). ret transforming gene encodes a fusion protein homologous to tyrosine kinases. Mol Cell Biol 7, 1378-1385.[Abstract/Free Full Text]

Treanor, J. J., Goodman, L., de Sauvage, F., Stone, D. M., Poulsen, K. T., Beck, C. D., Gray, C., Armanini, M. P., Pollock, R. A., Hefti, F. et al (1996). Characterization of a multicomponent receptor for GDNF. Nature 382, 80-83.[Medline]

Trupp, M., Arenas, E., Fainzilber, M., Nilsson, A. S., Sieber, B. A., Grigoriou, M., Kilkenny, C., Salazar-Grueso, E., Pachnis, V., Arumae, U. et al (1996). Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature 381, 785-788.[Medline]

Tsuzuki, T., Takahashi, M., Asai, N., Iwashita, T., Matsuyama, M. and Asai, J (1995). Spatial and temporal expression of the ret proto-oncogene product in embryonic, infant and adult rat tissues. Oncogene 10, 191-198.[Medline]

Vainio, S. and Muller, U (1997). Inductive tissue interactions, cell signaling, and the control of kidney organogenesis. Cell 90, 975-978.[Medline]

Vega, Q. C., Worby, C. A., Lechner, M. S., Dixon, J. E. and Dressler, G. R (1996). Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis. Proc. Natl. Acad. Sci. USA 93, 10657-10661.[Abstract/Free Full Text]

Vogels, R., Charite, J., de Graff, W. and Deschamps, J (1993). Proximal cis -acting elements cooperate to set Hoxb-7 (Hox-2.3) expression boundaries in transgenic mice. Development 118, 71-82.[Abstract]

Wehrle-Haller, B., Morrison-Graham, K. and Weston, J. A (1996). Ectopic c-kit expression affects the fate of melanocyte precursors in Patch mutant embryos. Dev. Biol 177, 463-474.[Medline]

Worby, C. A., Vega, Q. C., Zhao, Y., Chao, H. H. J., Seasholtz, A. F. and Dixon, J. E (1996). Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase. J. Biol. Chem 271, 23619-23622.[Abstract/Free Full Text]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

Z. Saifudeen, S. Dipp, J. Stefkova, X. Yao, S. Lookabaugh, and S. S. El-Dahr
p53 Regulates Metanephric Development
J. Am. Soc. Nephrol., November 1, 2009; 20(11): 2328 - 2337.
[Abstract] [Full Text] [PDF]

I. J. Murawski, D. B. Myburgh, J. Favor, and I. R. Gupta
Vesico-ureteric reflux and urinary tract development in the Pax21Neu+/ mouse
Am J Physiol Renal Physiol, November 1, 2007; 293(5): F1736 - F1745.
[Abstract] [Full Text] [PDF]

J. M. Linton, G. R. Martin, and L. F. Reichardt
The ECM protein nephronectin promotes kidney development via integrin {alpha}8{beta}1-mediated stimulation of Gdnf expression
Development, July 1, 2007; 134(13): 2501 - 2509.
[Abstract] [Full Text] [PDF]

M. Narlis, D. Grote, Y. Gaitan, S. K. Boualia, and M. Bouchard
Pax2 and Pax8 Regulate Branching Morphogenesis and Nephron Differentiation in the Developing Kidney
J. Am. Soc. Nephrol., April 1, 2007; 18(4): 1121 - 1129.
[Abstract] [Full Text] [PDF]

M. R. Zaidi, Y. Okada, and K. K. Chada
Misexpression of Full-length HMGA2 Induces Benign Mesenchymal Tumors in Mice.
Cancer Res., August 1, 2006; 66(15): 7453 - 7459.
[Abstract] [Full Text] [PDF]

S. Jain, M. Encinas, E. M. Johnson Jr., and J. Milbrandt
Critical and distinct roles for key RET tyrosine docking sites in renal development
Genes & Dev., February 1, 2006; 20(3): 321 - 333.
[Abstract] [Full Text] [PDF]

M. Yamamoto, L. Cui, K. Johkura, K. Asanuma, Y. Okouchi, N. Ogiwara, and K. Sasaki
Branching ducts similar to mesonephric ducts or ureteric buds in teratomas originating from mouse embryonic stem cells
Am J Physiol Renal Physiol, January 1, 2006; 290(1): F52 - F60.
[Abstract] [Full Text] [PDF]

X. Gao, X. Chen, M. Taglienti, B. Rumballe, M. H. Little, and J. A. Kreidberg
Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa
Development, December 15, 2005; 132(24): 5437 - 5449.
[Abstract] [Full Text] [PDF]

A. Wong, S. Bogni, P. Kotka, E. de Graaff, V. D'Agati, F. Costantini, and V. Pachnis
Phosphotyrosine 1062 Is Critical for the In Vivo Activity of the Ret9 Receptor Tyrosine Kinase Isoform
Mol. Cell. Biol., November 1, 2005; 25(21): 9661 - 9673.
[Abstract] [Full Text] [PDF]

H. K.W. Tse, M. B.W. Leung, A. S. Woolf, A. L. Menke, N. D. Hastie, J. A. Gosling, C.-P. Pang, and A. S.W. Shum
Implication of Wt1 in the Pathogenesis of Nephrogenic Failure in a Mouse Model of Retinoic Acid-Induced Caudal Regression Syndrome
Am. J. Pathol., May 1, 2005; 166(5): 1295 - 1307.
[Abstract] [Full Text] [PDF]

G. Schuetz, M. Rosario, J. Grimm, T. M. Boeckers, E. D. Gundelfinger, and W. Birchmeier
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells
J. Cell Biol., December 6, 2004; 167(5): 945 - 952.
[Abstract] [Full Text] [PDF]

O. H. Yu, I. J. Murawski, D. B. Myburgh, and I. R. Gupta
Overexpression of RET leads to vesicoureteric reflux in mice
Am J Physiol Renal Physiol, December 1, 2004; 287(6): F1123 - F1130.
[Abstract] [Full Text] [PDF]

S. Jain, C. K. Naughton, M. Yang, A. Strickland, K. Vij, M. Encinas, J. Golden, A. Gupta, R. Heuckeroth, E. M. Johnson Jr, et al.
Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis
Development, November 1, 2004; 131(21): 5503 - 5513.
[Abstract] [Full Text] [PDF]

A. Majumdar, S. Vainio, A. Kispert, J. McMahon, and A. P. McMahon
Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development
Development, July 15, 2003; 130(14): 3175 - 3185.
[Abstract] [Full Text] [PDF]

M. C. Hu, T. D. Piscione, and N. D. Rosenblum
Elevated SMAD1/{beta}-catenin molecular complexes and renal medullary cystic dysplasia in ALK3 transgenic mice
Development, June 15, 2003; 130(12): 2753 - 2766.
[Abstract] [Full Text] [PDF]

S. Puttini, A. T. Beggah, A. Ouvrard-Pascaud, C. Legris, M. Blot-Chabaud, N. Farman, and F. Jaisser
Tetracycline-inducible gene expression in cultured rat renal CD cells and in intact CD from transgenic mice
Am J Physiol Renal Physiol, December 1, 2001; 281(6): F1164 - F1172.
[Abstract] [Full Text] [PDF]

E. de Graaff, S. Srinivas, C. Kilkenny, V. D'Agati, B. S. Mankoo, F. Costantini, and V. Pachnis
Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis
Genes & Dev., September 15, 2001; 15(18): 2433 - 2444.
[Abstract] [Full Text] [PDF]

S. L. BULLOCK, T. M. JOHNSON, Q. BAO, R. C. HUGHES, P. J. D. WINYARD, and A. S. WOOLF
Galectin-3 Modulates Ureteric Bud Branching in Organ Culture of the Developing Mouse Kidney
J. Am. Soc. Nephrol., March 1, 2001; 12(3): 515 - 523.
[Abstract] [Full Text]

C. Gestblom, D. A. Sweetser, B. Doggett, and R. P. Kapur
Sympathoadrenal Hyperplasia Causes Renal Malformations in RetMEN2B-Transgenic Mice
Am. J. Pathol., December 1, 1999; 155(6): 2167 - 2179.
[Abstract] [Full Text] [PDF]

S. Quaggin, L Schwartz, S Cui, P Igarashi, J Deimling, M Post, and J Rossant
The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis
Development, January 12, 1999; 126(24): 5771 - 5783.
[Abstract] [PDF]

U Muller and A. Brandli
Cell adhesion molecules and extracellular-matrix constituents in kidney development and disease
J. Cell Sci., January 11, 1999; 112(22): 3855 - 3867.
[Abstract] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Srinivas, S.

Articles by Costantini, F.

Search for Related Content

PubMed

PubMed Citation

Articles by Srinivas, S.

Articles by Costantini, F.

Social Bookmarking

What's this?

				I. J. Murawski, D. B. Myburgh, J. Favor, and I. R. Gupta Vesico-ureteric reflux and urinary tract development in the Pax21Neu+/ mouse Am J Physiol Renal Physiol, November 1, 2007; 293(5): F1736 - F1745. [Abstract] [Full Text] [PDF]

				J. M. Linton, G. R. Martin, and L. F. Reichardt The ECM protein nephronectin promotes kidney development via integrin {alpha}8{beta}1-mediated stimulation of Gdnf expression Development, July 1, 2007; 134(13): 2501 - 2509. [Abstract] [Full Text] [PDF]

				M. Narlis, D. Grote, Y. Gaitan, S. K. Boualia, and M. Bouchard Pax2 and Pax8 Regulate Branching Morphogenesis and Nephron Differentiation in the Developing Kidney J. Am. Soc. Nephrol., April 1, 2007; 18(4): 1121 - 1129. [Abstract] [Full Text] [PDF]

				M. R. Zaidi, Y. Okada, and K. K. Chada Misexpression of Full-length HMGA2 Induces Benign Mesenchymal Tumors in Mice. Cancer Res., August 1, 2006; 66(15): 7453 - 7459. [Abstract] [Full Text] [PDF]

				S. Jain, M. Encinas, E. M. Johnson Jr., and J. Milbrandt Critical and distinct roles for key RET tyrosine docking sites in renal development Genes & Dev., February 1, 2006; 20(3): 321 - 333. [Abstract] [Full Text] [PDF]

				M. Yamamoto, L. Cui, K. Johkura, K. Asanuma, Y. Okouchi, N. Ogiwara, and K. Sasaki Branching ducts similar to mesonephric ducts or ureteric buds in teratomas originating from mouse embryonic stem cells Am J Physiol Renal Physiol, January 1, 2006; 290(1): F52 - F60. [Abstract] [Full Text] [PDF]

				X. Gao, X. Chen, M. Taglienti, B. Rumballe, M. H. Little, and J. A. Kreidberg Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa Development, December 15, 2005; 132(24): 5437 - 5449. [Abstract] [Full Text] [PDF]

				A. Wong, S. Bogni, P. Kotka, E. de Graaff, V. D'Agati, F. Costantini, and V. Pachnis Phosphotyrosine 1062 Is Critical for the In Vivo Activity of the Ret9 Receptor Tyrosine Kinase Isoform Mol. Cell. Biol., November 1, 2005; 25(21): 9661 - 9673. [Abstract] [Full Text] [PDF]

				H. K.W. Tse, M. B.W. Leung, A. S. Woolf, A. L. Menke, N. D. Hastie, J. A. Gosling, C.-P. Pang, and A. S.W. Shum Implication of Wt1 in the Pathogenesis of Nephrogenic Failure in a Mouse Model of Retinoic Acid-Induced Caudal Regression Syndrome Am. J. Pathol., May 1, 2005; 166(5): 1295 - 1307. [Abstract] [Full Text] [PDF]

				G. Schuetz, M. Rosario, J. Grimm, T. M. Boeckers, E. D. Gundelfinger, and W. Birchmeier The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells J. Cell Biol., December 6, 2004; 167(5): 945 - 952. [Abstract] [Full Text] [PDF]

				O. H. Yu, I. J. Murawski, D. B. Myburgh, and I. R. Gupta Overexpression of RET leads to vesicoureteric reflux in mice Am J Physiol Renal Physiol, December 1, 2004; 287(6): F1123 - F1130. [Abstract] [Full Text] [PDF]

				S. Jain, C. K. Naughton, M. Yang, A. Strickland, K. Vij, M. Encinas, J. Golden, A. Gupta, R. Heuckeroth, E. M. Johnson Jr, et al. Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis Development, November 1, 2004; 131(21): 5503 - 5513. [Abstract] [Full Text] [PDF]

				A. Majumdar, S. Vainio, A. Kispert, J. McMahon, and A. P. McMahon Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development Development, July 15, 2003; 130(14): 3175 - 3185. [Abstract] [Full Text] [PDF]

				M. C. Hu, T. D. Piscione, and N. D. Rosenblum Elevated SMAD1/{beta}-catenin molecular complexes and renal medullary cystic dysplasia in ALK3 transgenic mice Development, June 15, 2003; 130(12): 2753 - 2766. [Abstract] [Full Text] [PDF]

				S. Puttini, A. T. Beggah, A. Ouvrard-Pascaud, C. Legris, M. Blot-Chabaud, N. Farman, and F. Jaisser Tetracycline-inducible gene expression in cultured rat renal CD cells and in intact CD from transgenic mice Am J Physiol Renal Physiol, December 1, 2001; 281(6): F1164 - F1172. [Abstract] [Full Text] [PDF]

				E. de Graaff, S. Srinivas, C. Kilkenny, V. D'Agati, B. S. Mankoo, F. Costantini, and V. Pachnis Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis Genes & Dev., September 15, 2001; 15(18): 2433 - 2444. [Abstract] [Full Text] [PDF]

				S. L. BULLOCK, T. M. JOHNSON, Q. BAO, R. C. HUGHES, P. J. D. WINYARD, and A. S. WOOLF Galectin-3 Modulates Ureteric Bud Branching in Organ Culture of the Developing Mouse Kidney J. Am. Soc. Nephrol., March 1, 2001; 12(3): 515 - 523. [Abstract] [Full Text]

				C. Gestblom, D. A. Sweetser, B. Doggett, and R. P. Kapur Sympathoadrenal Hyperplasia Causes Renal Malformations in RetMEN2B-Transgenic Mice Am. J. Pathol., December 1, 1999; 155(6): 2167 - 2179. [Abstract] [Full Text] [PDF]

				S. Quaggin, L Schwartz, S Cui, P Igarashi, J Deimling, M Post, and J Rossant The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis Development, January 12, 1999; 126(24): 5771 - 5783. [Abstract] [PDF]

				U Muller and A. Brandli Cell adhesion molecules and extracellular-matrix constituents in kidney development and disease J. Cell Sci., January 11, 1999; 112(22): 3855 - 3867. [Abstract] [PDF]