Krox-20 controls SCIP expression, cell cycle exit and susceptibility to apoptosis in developing myelinating Schwann cells

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Zorick, T. S.
	Articles by Lemke, G.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Zorick, T. S.
	Articles by Lemke, G.

Adlkofer, K., Martini, R., Aguzzi, A., Zielasek, J., Toyka, K. V. and Suter, U (1995). Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice. Nat. Genet 11, 274-280.[Medline]

Barres, B. A., Hart, I. K., Coles, H. S., Burne, J. F., Voyvodic, J. T., Richardson, W. D. and Raff, M. C (1992). Cell death and control of cell survival in the oligodendrocyte lineage. Cell 70, 31-46.[Medline]

Barres, B. A. and Raff, M. C (1994). Control of oligodendrocyte number in the developing rat optic nerve. Neuron 12, 935-942.[Medline]

Bermingham, J. R. j., Scherer, S. S., O'Connell, S., Arroyo, E., Kalla, K. A., Powell, F. L. and Rosenfeld, M. G (1996). Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes Dev 10, 1751-1762.[Abstract/Free Full Text]

Bhat, K. M., Poole, S. J. and Schedl, P (1995). The miti-mere and pdm1 genes collaborate during specification of the RP2/sib lineage in Drosophila neurogenesis. Mol. Cell. Biol 15, 4052-4063.[Abstract]

Bhat, K. M. and Schedl, P (1994). The Drosophila miti-mere gene, a member of the POU family, is required for the specification of the RP2/sibling lineage during neurogenesis. Development 120, 1483-1501.[Abstract]

Blanchard, A. D., Sinanan, A., Parmantier, E., Zwart, R., Broos, L., Meijer, D., Meier, C., Jessen, K. R. and Mirsky, R (1996). Oct-6 (SCIP/Tst-1) is expressed in Schwann cell precursors, embryonic Schwann cells, and postnatal myelinating Schwann cells: comparison with Oct-1, Krox-20, and Pax-3. J. Neurosci. Res 46, 630-640.[Medline]

Brown, A. and Lemke, G (1997). Multiple regulatory elements control transcription of the peripheral myelin protein zero gene. J. Biol. Chem 272, 28939-28947.[Abstract/Free Full Text]

Brown, M. J. and Asbury, A. K (1981). Schwann cell proliferation in the postnatal mouse: timing and topography. Exp. Neurol 74, 170-186.[Medline]

Chomczynski, P. and Sacchi, N (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem 162, 156-159.[Medline]

Collarini, E. J., Kuhn, R., Marshall, C. J., Monuki, E. S., Lemke, G. and Richardson, W. D (1992). Down-regulation of the POU transcription factor SCIP is an early event in oligodendrocyte differentiation in vitro. Development 116, 193-200.[Abstract]

Faus, I., Hsu, H.-J. and Fuchs, E (1994). Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia. Mol. Cell. Biol 14, 3263-3275.[Abstract/Free Full Text]

Frantz, G. D., Bohner, A. P., Akers, R. M. and McConnell, S. K (1994). Regulation of the POU domain gene SCIP during cerebral cortical development. J. Neurosci 14, 472-485.[Abstract]

Friede, R. L. and Samorajski, T (1968). Myelin formation in the sciatic nerve of the rat. A quantitative electron microscopic, histochemical and radioautographic study. J. Neuropathol. Exp. Neurol 27, 546-570.[Medline]

Grinspan, J. B., Marchionni, M. A., Reeves, M., Coulaloglou, M. and Scherer, S. S (1996). Axonal interactions regulate Schwann cell apoptosis in developing peripheral nerve: neuregulin receptors and the role of neuregulins. J. Neurosci 16, 6107-6118.[Abstract/Free Full Text]

Hasel, K. W. and Sutcliffe, J. G (1990). Nucleotide sequence of a cDNA coding for mouse cyclophilin. Nucleic Acids Res 18, 4019-.[Free Full Text]

Herr, W. and Cleary, M. A (1995). The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain. Genes Dev 9, 1679-1693.[Free Full Text]

Jaegle, M. and Meijer, D (1998). Role of Oct-6 in Schwann cell differentiation. Microsc. Res. Tech 41, 372-378.[Medline]

Jaegle, M., Mandemakers, W., Broos, L., Zwart, R., Karls, A., Visser, P., Grosveld, F. and Meijer, D (1996). The POU factor Oct-6 and Schwann cell differentiation. Science 273, 507-510.[Abstract]

Jessen, K. R., Brennan, A., Morgan, L., Mirsky, R., Kent, A., Hashimoto, Y. and Gavrilovic, J (1994). The Schwann cell precursor and its fate: a study of cell death and differentiation during gliogenesis in rat embryonic nerves. Neuron 12, 509-527.[Medline]

Krieg, P. A. and Melton, D. A (1987). In vitro RNA synthesis with SP6 RNA polymerase. Meth. Enzymol 155, 397-415.[Medline]

Leger, H., Sock, E., Renner, K., Grummt, F. and Wegner, M (1995). Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y. Mol. Cell. Biol 15, 3738-3747.[Abstract]

Lemke, G., Lamar, E. and Patterson, J (1988). Isolation and analysis of the gene encoding peripheral myelin protein zero. Neuron 1, 73-83.[Medline]

Martin, J. R. and Webster, H. D (1973). Mitotic Schwann cells in developing nerve: their changes in shape, fine structure, and axon relationships. Dev. Biol 32, 417-431.[Medline]

Messing, A., Behringer, R. R., Hammang, J. P., Palmiter, R. D., Brinster, R. L. and Lemke, G (1992). P0promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice. Neuron 8, 507-520.[Medline]

Mirsky, R. and Jessen, K. R (1996). Schwann cell development, differentiation, and myelination. Curr. Opin. Neurobiol 6, 89-96.[Medline]

Monuki, E. S., Kuhn, R. and Lemke, G (1993). Repression of the myelin P0gene by the POU transcription factor SCIP. Mech. Dev 42, 15-32.[Medline]

Monuki, E. S., Kuhn, R., Weinmaster, G., Trapp, B. D. and Lemke, G (1990). Expression and activity of the POU transcription factor SCIP. Science 249, 1300-1303.[Abstract/Free Full Text]

Monuki, E. S., Weinmaster, G., Kuhn, R. and Lemke, G (1989). SCIP: A glial cell POU domain gene regulated by cyclic AMP. Neuron 3, 783-793.[Medline]

Murphy, P., Topilko, P., Schneider-Maunoury, S., Seitanidou, T., Baron-Van Evercooren, A. and Charnay, P (1996). The regulation of Krox-20 expression reveals important steps in the control of peripheral glial cell development. Development 122, 2847-2857.[Abstract]

Nakao, J., Shinoda, J., Nakai, Y., Murase, S. and Uyemura, K (1997). Apoptosis regulates the number of Schwann cells at the premyelinating stage. J. Neurochem 68, 1853-1862.[Medline]

Peters, A. and Muir, A. R (1958). The relationship between axons and Schwann cells during development of peripheral nerves in the rat. Quart. J. Exp. Physiol 44, 117-130.

Peterson, D. A., Leppert, J. T., Lee, K. F. and Gage, F. H (1997). Basal forebrain neuronal loss in mice lacking neurotrophin receptor p75 [letter]. Science 277, 837-839.[Free Full Text]

Peterson, D. A., Lucidi-Phillipi, C. A., Eagle, K. L. and Gage, F. H (1994). Perforant path damage results in progressive neuronal death and somal atrophy in layer II of entorhinal cortex and functional impairment with increasing postdamage age. J. Neurosci 14, 6872-6885.[Abstract]

Peterson, D. A., Lucidi-Phillipi, C. A., Murphy, D. P., Ray, J. and Gage, F. H (1996). Fibroblast growth factor-2 protects entorhinal layer II glutamatergic neurons from axotomy-induced death. J. Neurosci 16, 886-898.[Abstract/Free Full Text]

Scherer, S. S., Wang, D. Y., Kuhn, R., Lemke, G., Wrabetz, L. andKamholz, J (1994). Axons regulate Schwann cell expression of the POU transcription factor SCIP. J. Neurosci 14, 1930-1942.[Abstract]

Schneider-Maunoury, S., Topilko, P., Seitandou, T., Levi, G., Cohen-Tannoudji, M., Pournin, S., Babinet, C. and Charnay, P (1993). Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell 75, 1199-1214.[Medline]

Schreiber, J., Enderich, J., Sock, E., Schmidt, C., Richter-Landsberg, C. and Wegner, M (1997). Redundancy of class III POU proteins in the oligodendrocyte lineage. J. Biol. Chem 272, 32286-32293.[Abstract/Free Full Text]

Sereda, M., Griffiths, I., Puhlhofer, A., Stewart, H., Rossner, M. J., Zimmerman, F., Magyar, J. P., Schneider, A., Hund, E., Meinck, H. M. et al (1996). A transgenic rat model of Charcot-Marie-Tooth disease. Neuron 16, 1049-1060.[Medline]

Stewart, H. J., Morgan, L., Jessen, K. R. and Mirsky, R (1993). Changes in DNA synthesis rate in the Schwann cell lineage in vivo are correlated with the precursor\321Schwann cell transition and myelination. Eur. J. Neurosci 5, 1136-1144.[Medline]

Suzuki, N., Rohdewohld, H., Neuman, T., Gruss, P., and Scholer, H.R (1990). Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain. EMBO J 9, 3723-3732.[Medline]

Swiatek, P. J. and Gridley, T (1993). Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20. Genes Dev 7, 2071-2084.[Abstract/Free Full Text]

Syroid, D. E., Maycox, P. R., Burrola, P. G., Liu, N., Wen, D., Lee, K.-F., Lemke, G. and Kilpatrick, T. J (1996). Cell death in the Schwann cell lineage and its regulation by neuregulin. Proc. Natl. Acad. Sci. USA 93, 9229-9234.[Abstract/Free Full Text]

Taylor, V. and Suter, U (1997). Molecular biology of axon-glia interactions in the peripheral nervous system. Prog. Nucleic Acid Res. Mol. Biol 56, 225-256.[Medline]

Thomaidou, D., Mione, M.C., Cavanagh, J.F., and Parnavelas, J.G (1997). Apoptosis and its relation to the cell cycle in the developing cerebral cortex. J. Neurosci 17, 1075-85.[Abstract/Free Full Text]

Topilko, P., Schneider-Maunoury, S., Levi, G., Baron-Van Evercooren, A., Chennoufi, A. B., Seitanidou, T., Babinet, C. and Charnay, P (1994). Krox-20 controls myelination in the peripheral nervous system. Nature 371, 796-799.[Medline]

Trachtenberg, J. T. and Thompson, W. J (1996). Schwann cell apoptosis at developing neuromuscular junctions is regulated by glial growth factor. Nature 379, 174-177.[Medline]

Webster, H. D., Martin, R. and O'Connell, M. F (1973). The relationships between interphase Schwann cells and axons before myelination: a quantitative electron microscopic study. Dev. Biol 32, 401-416.[Medline]

Weinstein, D. E., Burrola, P. G. and Lemke, G (1995). Premature Schwann cell differentiation and hypermyelination in mice expressing a targeted antagonist of the POU transcription factor SCIP. Mol. Cell. Neurosci 6, 212-229.[Medline]

West, M. J (1993). New stereological methods for counting neurons. Neurobiol. Aging 14, 275-285.[Medline]

West, M. J. and Gundersen, H. J (1990). Unbiased stereological estimation of the number of neurons in the human hippocampus. J. Comp. Neurol 296, 1-22.[Medline]

You, K. H., Hsieh, C. L., Hayes, C., Stahl, N., Francke, U. and Popko, B (1991). DNA sequence, genomic organization, and chromosomal localization of the mouse peripheral myelin protein zero gene: identification of polymorphic alleles. Genomics 9, 751-757.[Medline]

Zorick, T. S. and Lemke, G (1996). Schwann cell differentiation. Curr. Opin. Cell. Biol 8, 870-876.[Medline]

Zorick, T. S., Syroid, D. E., Arroyo, E., Scherer, S. S. and Lemke, G (1996). The transcription factors SCIP and Krox-20 mark distinct stages and cell fates in Schwann cell differentiation. Mol. Cell. Neurosci 8, 129-146.[Medline]

This article has been cited by other articles:

G. M. Mager, R. M. Ward, R. Srinivasan, S.-W. Jang, L. Wrabetz, and J. Svaren
Active Gene Repression by the Egr2{middle dot}NAB Complex during Peripheral Nerve Myelination
J. Biol. Chem., June 27, 2008; 283(26): 18187 - 18197.
[Abstract] [Full Text] [PDF]

A. Desmazieres, L. Decker, J.-M. Vallat, P. Charnay, and P. Gilardi-Hebenstreit
Disruption of Krox20-Nab Interaction in the Mouse Leads to Peripheral Neuropathy with Biphasic Evolution
J. Neurosci., June 4, 2008; 28(23): 5891 - 5900.
[Abstract] [Full Text] [PDF]

E. J. Ryu, J. Y. T. Wang, N. Le, R. H. Baloh, J. A. Gustin, R. E. Schmidt, and J. Milbrandt
Misexpression of Pou3f1 Results in Peripheral Nerve Hypomyelination and Axonal Loss
J. Neurosci., October 24, 2007; 27(43): 11552 - 11559.
[Abstract] [Full Text] [PDF]

S. E. LeBlanc, R. M. Ward, and J. Svaren
Neuropathy-Associated Egr2 Mutants Disrupt Cooperative Activation of Myelin Protein Zero by Egr2 and Sox10
Mol. Cell. Biol., May 1, 2007; 27(9): 3521 - 3529.
[Abstract] [Full Text] [PDF]

S. E. LeBlanc, S.-W. Jang, R. M. Ward, L. Wrabetz, and J. Svaren
Direct Regulation of Myelin Protein Zero Expression by the Egr2 Transactivator
J. Biol. Chem., March 3, 2006; 281(9): 5453 - 5460.
[Abstract] [Full Text] [PDF]

W.-M. Yu, M. L. Feltri, L. Wrabetz, S. Strickland, and Z.-L. Chen
Schwann Cell-Specific Ablation of Laminin {gamma}1 Causes Apoptosis and Prevents Proliferation
J. Neurosci., May 4, 2005; 25(18): 4463 - 4472.
[Abstract] [Full Text] [PDF]

N. Le, R. Nagarajan, J. Y. T. Wang, T. Araki, R. E. Schmidt, and J. Milbrandt
Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination
PNAS, February 15, 2005; 102(7): 2596 - 2601.
[Abstract] [Full Text] [PDF]

D. B. Parkinson, A. Bhaskaran, A. Droggiti, S. Dickinson, M. D'Antonio, R. Mirsky, and K. R. Jessen
Krox-20 inhibits Jun-NH2-terminal kinase/c-Jun to control Schwann cell proliferation and death
J. Cell Biol., February 2, 2004; 164(3): 385 - 394.
[Abstract] [Full Text] [PDF]

M. H.G. Verheijen, R. Chrast, P. Burrola, and G. Lemke
Local regulation of fat metabolism in peripheral nerves
Genes & Dev., October 1, 2003; 17(19): 2450 - 2464.
[Abstract] [Full Text] [PDF]

S. G. Slutsky, A. K. Kamaraju, A. M. Levy, J. Chebath, and M. Revel
Activation of Myelin Genes during Transdifferentiation from Melanoma to Glial Cell Phenotype
J. Biol. Chem., March 7, 2003; 278(11): 8960 - 8968.
[Abstract] [Full Text] [PDF]

J. Ghislain, C. Desmarquet-Trin-Dinh, M. Jaegle, D. Meijer, P. Charnay, and M. Frain
Characterisation of cis-acting sequences reveals a biphasic, axon-dependent regulation of Krox20 during Schwann cell development
Development, January 1, 2002; 129(1): 155 - 166.
[Abstract] [Full Text] [PDF]

L. S. Sherman, T. A. Rizvi, S. Karyala, and N. Ratner
CD44 Enhances Neuregulin Signaling by Schwann Cells
J. Cell Biol., September 5, 2000; 150(5): 1071 - 1084.
[Abstract] [Full Text] [PDF]

R. I. Peirano, D. E. Goerich, D. Riethmacher, and M. Wegner
Protein Zero Gene Expression Is Regulated by the Glial Transcription Factor Sox10
Mol. Cell. Biol., May 1, 2000; 20(9): 3198 - 3209.
[Abstract] [Full Text]

B. Stevens and R. D. Fields
Response of Schwann Cells to Action Potentials in Development
Science, March 24, 2000; 287(5461): 2267 - 2271.
[Abstract] [Full Text]

L. Wrabetz, M. L. Feltri, A. Quattrini, D. Imperiale, S. Previtali, M. D'Antonio, R. Martini, X. Yin, B. D. Trapp, L. Zhou, et al.
P0 Glycoprotein Overexpression Causes Congenital Hypomyelination of Peripheral Nerves
J. Cell Biol., March 6, 2000; 148(5): 1021 - 1034.
[Abstract] [Full Text] [PDF]

A. N. Garratt, O. Voiculescu, P. Topilko, P. Charnay, and C. Birchmeier
A Dual Role of erbB2 in Myelination and in Expansion of the Schwann Cell Precursor Pool
J. Cell Biol., March 6, 2000; 148(5): 1035 - 1046.
[Abstract] [Full Text] [PDF]

L. E. Warner, J. Svaren, J. Milbrandt, and J. R. Lupski
Functional consequences of mutations in the early growth response 2 gene (EGR2) correlate with severity of human myelinopathies
Hum. Mol. Genet., July 1, 1999; 8(7): 1245 - 1251.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Zorick, T. S.

Articles by Lemke, G.

Search for Related Content

PubMed

PubMed Citation

Articles by Zorick, T. S.

Articles by Lemke, G.

				A. Desmazieres, L. Decker, J.-M. Vallat, P. Charnay, and P. Gilardi-Hebenstreit Disruption of Krox20-Nab Interaction in the Mouse Leads to Peripheral Neuropathy with Biphasic Evolution J. Neurosci., June 4, 2008; 28(23): 5891 - 5900. [Abstract] [Full Text] [PDF]

				E. J. Ryu, J. Y. T. Wang, N. Le, R. H. Baloh, J. A. Gustin, R. E. Schmidt, and J. Milbrandt Misexpression of Pou3f1 Results in Peripheral Nerve Hypomyelination and Axonal Loss J. Neurosci., October 24, 2007; 27(43): 11552 - 11559. [Abstract] [Full Text] [PDF]

				S. E. LeBlanc, R. M. Ward, and J. Svaren Neuropathy-Associated Egr2 Mutants Disrupt Cooperative Activation of Myelin Protein Zero by Egr2 and Sox10 Mol. Cell. Biol., May 1, 2007; 27(9): 3521 - 3529. [Abstract] [Full Text] [PDF]

				S. E. LeBlanc, S.-W. Jang, R. M. Ward, L. Wrabetz, and J. Svaren Direct Regulation of Myelin Protein Zero Expression by the Egr2 Transactivator J. Biol. Chem., March 3, 2006; 281(9): 5453 - 5460. [Abstract] [Full Text] [PDF]

				W.-M. Yu, M. L. Feltri, L. Wrabetz, S. Strickland, and Z.-L. Chen Schwann Cell-Specific Ablation of Laminin {gamma}1 Causes Apoptosis and Prevents Proliferation J. Neurosci., May 4, 2005; 25(18): 4463 - 4472. [Abstract] [Full Text] [PDF]

				N. Le, R. Nagarajan, J. Y. T. Wang, T. Araki, R. E. Schmidt, and J. Milbrandt Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination PNAS, February 15, 2005; 102(7): 2596 - 2601. [Abstract] [Full Text] [PDF]

				D. B. Parkinson, A. Bhaskaran, A. Droggiti, S. Dickinson, M. D'Antonio, R. Mirsky, and K. R. Jessen Krox-20 inhibits Jun-NH2-terminal kinase/c-Jun to control Schwann cell proliferation and death J. Cell Biol., February 2, 2004; 164(3): 385 - 394. [Abstract] [Full Text] [PDF]

				M. H.G. Verheijen, R. Chrast, P. Burrola, and G. Lemke Local regulation of fat metabolism in peripheral nerves Genes & Dev., October 1, 2003; 17(19): 2450 - 2464. [Abstract] [Full Text] [PDF]

				S. G. Slutsky, A. K. Kamaraju, A. M. Levy, J. Chebath, and M. Revel Activation of Myelin Genes during Transdifferentiation from Melanoma to Glial Cell Phenotype J. Biol. Chem., March 7, 2003; 278(11): 8960 - 8968. [Abstract] [Full Text] [PDF]

				J. Ghislain, C. Desmarquet-Trin-Dinh, M. Jaegle, D. Meijer, P. Charnay, and M. Frain Characterisation of cis-acting sequences reveals a biphasic, axon-dependent regulation of Krox20 during Schwann cell development Development, January 1, 2002; 129(1): 155 - 166. [Abstract] [Full Text] [PDF]

				L. S. Sherman, T. A. Rizvi, S. Karyala, and N. Ratner CD44 Enhances Neuregulin Signaling by Schwann Cells J. Cell Biol., September 5, 2000; 150(5): 1071 - 1084. [Abstract] [Full Text] [PDF]

				R. I. Peirano, D. E. Goerich, D. Riethmacher, and M. Wegner Protein Zero Gene Expression Is Regulated by the Glial Transcription Factor Sox10 Mol. Cell. Biol., May 1, 2000; 20(9): 3198 - 3209. [Abstract] [Full Text]

				B. Stevens and R. D. Fields Response of Schwann Cells to Action Potentials in Development Science, March 24, 2000; 287(5461): 2267 - 2271. [Abstract] [Full Text]

				L. Wrabetz, M. L. Feltri, A. Quattrini, D. Imperiale, S. Previtali, M. D'Antonio, R. Martini, X. Yin, B. D. Trapp, L. Zhou, et al. P0 Glycoprotein Overexpression Causes Congenital Hypomyelination of Peripheral Nerves J. Cell Biol., March 6, 2000; 148(5): 1021 - 1034. [Abstract] [Full Text] [PDF]

				A. N. Garratt, O. Voiculescu, P. Topilko, P. Charnay, and C. Birchmeier A Dual Role of erbB2 in Myelination and in Expansion of the Schwann Cell Precursor Pool J. Cell Biol., March 6, 2000; 148(5): 1035 - 1046. [Abstract] [Full Text] [PDF]

				L. E. Warner, J. Svaren, J. Milbrandt, and J. R. Lupski Functional consequences of mutations in the early growth response 2 gene (EGR2) correlate with severity of human myelinopathies Hum. Mol. Genet., July 1, 1999; 8(7): 1245 - 1251. [Abstract] [Full Text] [PDF]