C. elegans MAC-1, an essential member of the AAA family of ATPases, can bind CED-4 and prevent cell death

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Beyer, A (1997). Sequence analysis of the AAA protein family. Protein Science 6, 2043-58.[Medline]

Brenner, S (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94.[Abstract/Free Full Text]

Candido, E. P., Jones, D., Dixon, D. K., Graham, R. W., Russnak, R. H. and Kay, R. J (1989). Structure, organization, and expression of the 16-kDa heat shock gene family of Caenorhabditis elegans. Genome 31, 690-697.[Medline]

Chinnaiyan, A. M., O'Rourke, K., Lane, B. R. and Dixit, V. M (1997). Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science 275, 1122-1126.[Abstract/Free Full Text]

Cohen, G. M (1997). Caspases: the executioners of apoptosis. Biochemical Journal 326, 1-16.

Confalonieri, F. and Duguet, M (1995). A 200-amino acid ATPase module in search of a basic function. Bioessays 17, 639-650.[Medline]

Dai, R. M., Chen, E., Longo, D. L., Gorbea, C. M. and Li, C. C (1998). Involvement of valosin-containing protein, an ATPase Co-purified with IB and 26 S proteasome, in ubiquitin-proteasome-mediated degradation of IB. J. Biol. Chem 273, 3562-3573.[Abstract/Free Full Text]

Egerton, M., Ashe, O. R., Chen, D., Druker, B. J., Burgess, W. H. and Samelson, L. E (1992). VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation. EMBO J 11, 3533-3540.[Medline]

Ellis, H. M. and Horvitz, H. R (1986). Genetic control of programmed cell death in the nematode C. elegans. Cell 44, 817-829.[Medline]

Ellis, R. E. and Horvitz, H. R (1991). Two C. elegans genes control the programmed deaths of specific cells in the pharynx. Development 112, 591-603.[Abstract]

Ellis, R. E., Yuan, J. Y. and Horvitz, H. R (1991). Mechanisms and functions of cell death. Ann. Rev. Cell Biol 7, 663-698.

Fire, A (1986). Integrative transformation of Caenorhabditis elegans. EMBO J 5, 2673-2680.[Medline]

Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E. and Mello, C. C (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811.[Medline]

Fr\232hlich, K. U., Fries, H. W., Rudiger, M., Erdmann, R., Botstein, D. and Mecke, D (1991). Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression. J. Cell Biol 114, 443-453.[Abstract/Free Full Text]

Guo, S. and Kemphues, K. J (1995). par-1 , a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81, 611-620.[Medline]

Hengartner, M. O., Ellis, R. E. and Horvitz, H. R (1992). Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature 356, 494-499.[Medline]

Hengartner, M. O. and Horvitz, H. R (1994). C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 76, 665-676.[Medline]

Hofmann, K., Bucher, P. and Tschopp, J (1997). The CARD domain: a new apoptotic signalling motif. Trends Biochem. Sci 22, 155-156.[Medline]

Hu, Y., Benedict, M. A., Wu, D., Inohara, N. and Nunez, G (1998). Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc. Natl. Acad. Sci. USA 95, 4386-4391.[Abstract/Free Full Text]

Hunter, C. P. and Kenyon, C (1996). Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos. Cell 87, 217-226.[Medline]

James, C., Gschmeissner, S., Fraser, A. and Evan, G. I (1997). CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9. Curr. Biol 7, 246-52.[Medline]

Krause, M. and Hirsh, D (1987). A trans-spliced leader sequence on actin mRNA in C. elegans. Cell 49, 753-761.[Medline]

Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X (1997). Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489.[Medline]

Lin, R., Thompson, S. and Priess, J. R (1995). pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos. Cell 83, 599-609.[Medline]

Long, A. R., Yang, M., Kaiser, K. and Shepherd, D (1998). Isolation and characterisation of smallminded, a Drosophila gene encoding a new member of the Cdc48p/VCP subfamily of AAA proteins. Gene 208, 191-199.[Medline]

Madeo, F., Fr\232hlich, E. and Fr\232hlich, K. U (1997). A yeast mutant showing diagnostic markers of early and late apoptosis. J. Cell Biol 139, 729-734.[Abstract/Free Full Text]

Madeo, F., Schlauer, J. and Fr\232hlich, K. U (1997). Identification of the regions of porcine VCP preventing its function in Saccharomyces cerevisiae. Gene 204, 145-151.[Medline]

Mello, C. C., Kramer, J. M., Stinchcomb, D. and Ambros, V (1991). Efficient gene transfer in C.elegans : extrachromosomal maintenance and integration of transforming sequences. EMBO J 10, 3959-3970.[Medline]

Metzstein, M. M., Hengartner, M. O., Tsung, N., Ellis, R. E. and Horvitz, H. R (1996). Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2. Nature 382, 545-547.[Medline]

Miller, D. M., Shen, M. M., Shamu, C. E., Burglin, T. R., Ruvkun, G., Dubois, M. L., Ghee, M. and Wilson, L (1992). C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons. Nature 355, 841-845.[Medline]

Miura, M., Zhu, H., Rotello, R., Hartwieg, E. A. and Yuan, J (1993). Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75, 653-660.[Medline]

Pan, G., O'Rourke, K. and Dixit, V. M (1998). Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex. J. Biol. Chem 273, 5841-5845.[Abstract/Free Full Text]

Pleasure, I. T., Black, M. M. and Keen, J. H (1993). Valosin-containing protein, VCP, is a ubiquitous clathrin-binding protein. Nature 365, 459-462.[Medline]

Rabouille, C., Levine, T. P., Peters, J. M. and Warren, G (1995). An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments. Cell 82, 905-914.[Medline]

Rocheleau, C. E., Downs, W. D., Lin, R., Wittmann, C., Bei, Y., Cha, Y. H., Ali, M., Priess, J. R. and Mello, C. C (1997). Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos. Cell 90, 707-716.[Medline]

Shaham, S., and Horvitz, H. R (1996). Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities. Genes Dev 10, 578-591.[Abstract/Free Full Text]

Spector, M. S., Desnoyers, S., Hoeppner, D. J. and Hengartner, M. O (1997). Interaction between the C. elegans cell-death regulators CED-9 and CED-4. Nature 385, 653-656.[Medline]

Sulston, J. E. and Brenner, S (1974). The DNA of Caenorhabditis elegans. Genetics 77, 95-104.[Abstract/Free Full Text]

Sulston, J. E. and Horvitz, H. R (1977). Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev. Biol 56, 110-156.[Medline]

Sulston, J., Du, Z., Thomas, K., Wilson, R., Hillier, L., Staden, R., Halloran, N., Green, P., Thierry-Mieg, J., Qiu, L. and et al (1992). The C. elegans genome sequencing project: a beginning. Nature 356, 37-41.[Medline]

Sulston, J. E., Schierenberg, E., White, J. G. and Thomson, J. N (1983). The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev. Biol 100, 64-119.[Medline]

Swaffield, J. C. and Purugganan, M. D (1997). The evolution of the conserved ATPase domain (CAD): reconstructing the history of an ancient protein module. J. Mol. Evol 45, 549-563.[Medline]

Tschopp, J., Thome, M., Hofmann, K. and Meinl, E (1998). The fight of viruses against apoptosis. Curr. Opin. Genet. Dev 8, 82-87.[Medline]

White, J. G., Southgate, E. and Thomson, J. N (1992). Mutations in the Caenorhabditis elegans unc-4 gene alter the synaptic input to ventral cord motor neurons. Nature 355, 838-841.[Medline]

Wu, D., Wallen, H. D., Inohara, N. and Nunez, G (1997). Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9. J. Biol. Chem 272, 21449-21454.[Abstract/Free Full Text]

Wu, D., Wallen, H. D. and Nunez, G (1997). Interaction and regulation of subcellular localization of CED-4 by CED-9. Science 275, 1126-1129.[Abstract/Free Full Text]

Yuan, J. and Horvitz, H. R (1992). The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death. Development 116, 309-320.[Medline]

Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M. and Horvitz, H. R (1993). The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 75, 641-652.[Medline]

Yuan, J. Y. and Horvitz, H. R (1990). The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev. Biol 138, 33-41.[Medline]

Zou, H., Henzel, W. J., Liu, X., Lutschg, A. and Wang, X (1997). Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-413.[Medline]

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				M. Nagahama, Y. Hara, A. Seki, T. Yamazoe, Y. Kawate, T. Shinohara, K. Hatsuzawa, K. Tani, and M. Tagaya NVL2 Is a Nucleolar AAA-ATPase that Interacts with Ribosomal Protein L5 through Its Nucleolar Localization Sequence Mol. Biol. Cell, December 1, 2004; 15(12): 5712 - 5723. [Abstract] [Full Text] [PDF]

				S. Wissing, P. Ludovico, E. Herker, S. Buttner, S. M. Engelhardt, T. Decker, A. Link, A. Proksch, F. Rodrigues, M. Corte-Real, et al. An AIF orthologue regulates apoptosis in yeast J. Cell Biol., October 4, 2004; (2004) jcb.200404138. [Abstract] [Full Text] [PDF]

				R. V. Rao, K. S. Poksay, S. Castro-Obregon, B. Schilling, R. H. Row, G. del Rio, B. W. Gibson, H. M. Ellerby, and D. E. Bredesen Molecular Components of a Cell Death Pathway Activated by Endoplasmic Reticulum Stress J. Biol. Chem., January 2, 2004; 279(1): 177 - 187. [Abstract] [Full Text] [PDF]

				M. Ligr, I. Velten, E. Frohlich, F. Madeo, M. Ledig, K.-U. Frohlich, D. H. Wolf, and W. Hilt The Proteasomal Substrate Stm1 Participates in Apoptosis-like Cell Death in Yeast Mol. Biol. Cell, August 1, 2001; 12(8): 2422 - 2432. [Abstract] [Full Text] [PDF]

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