The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation

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T. Wendl, K. Lun, M. Mione, J. Favor, M. Brand, S. W. Wilson, and K. B. Rohr
pax2.1 is required for the development of thyroid follicles in zebrafish
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V. V. Kalinichenko, Y. Zhou, D. Bhattacharyya, W. Kim, B. Shin, K. Bambal, and R. H. Costa
Haploinsufficiency of the Mouse Forkhead Box f1 Gene Causes Defects in Gall Bladder Development
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A. V. D'Elia, G. Tell, D. Russo, F. Arturi, F. Puglisi, G. Manfioletti, V. Gattei, D. L. Mack, P. Cataldi, S. Filetti, et al.
Expression and Localization of the Homeodomain-Containing Protein HEX in Human Thyroid Tumors
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G. Lupo, W. A. Harris, G. Barsacchi, and R. Vignali
Induction and patterning of the telencephalon in Xenopus laevis
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Z. Sun and N. Hopkins
vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain
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S. A. Duncan and A. J. Watt
BMPs on the road to hepatogenesis
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P. A. Hoodless, M. Pye, C. Chazaud, E. Labbé, L. Attisano, J. Rossant, and J. L. Wrana
FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse
Genes & Dev., May 15, 2001; 15(10): 1257 - 1271.
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D. H. Gorski and K. Walsh
Control of Vascular Cell Differentiation by Homeiobox Transcription Factors
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A Perea-Gomez, K. Lawson, M Rhinn, L Zakin, P Brulet, S Mazan, and S. Ang
Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo
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S Withington, R Beddington, and J Cooke
Foregut endoderm is required at head process stages for anteriormost neural patterning in chick
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D. H. Gorski and K. Walsh
The Role of Homeobox Genes in Vascular Remodeling and Angiogenesis
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				B. Jin, Q. Tao, J. Peng, H. M. Soo, W. Wu, J. Ying, C. R. Fields, A. L. Delmas, X. Liu, J. Qiu, et al. DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function Hum. Mol. Genet., March 1, 2008; 17(5): 690 - 709. [Abstract] [Full Text] [PDF]

				Y. Seino, T. Miki, H. Kiyonari, T. Abe, W. Fujimoto, K. Kimura, A. Takeuchi, Y. Takahashi, Y. Oiso, T. Iwanaga, et al. Isx Participates in the Maintenance of Vitamin A Metabolism by Regulation of {beta}-Carotene 15,15'-Monooxygenase (Bcmo1) Expression J. Biol. Chem., February 22, 2008; 283(8): 4905 - 4911. [Abstract] [Full Text] [PDF]

				A. Di-Gregorio, M. Sancho, D. W. Stuckey, L. A. Crompton, J. Godwin, Y. Mishina, and T. A. Rodriguez BMP signalling inhibits premature neural differentiation in the mouse embryo Development, September 15, 2007; 134(18): 3359 - 3369. [Abstract] [Full Text] [PDF]

				V. A. McLin, S. A. Rankin, and A. M. Zorn Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas development Development, June 15, 2007; 134(12): 2207 - 2217. [Abstract] [Full Text] [PDF]

				E. Al Taji, H. Biebermann, Z. Limanova, O. Hnikova, J. Zikmund, C. Dame, A. Gruters, J. Lebl, and H. Krude Screening for mutations in transcription factors in a Czech cohort of 170 patients with congenital and early-onset hypothyroidism: identification of a novel PAX8 mutation in dominantly inherited early-onset non-autoimmune hypothyroidism Eur. J. Endocrinol., May 1, 2007; 156(5): 521 - 529. [Abstract] [Full Text] [PDF]

				S. Vijayakumar, J. Takito, X. Gao, G. J. Schwartz, and Q. Al-Awqati Differentiation of columnar epithelia: the hensin pathway J. Cell Sci., December 1, 2006; 119(23): 4797 - 4801. [Abstract] [Full Text] [PDF]

				A. L. Zamparini, T. Watts, C. E. Gardner, S. R. Tomlinson, G. I. Johnston, and J. M. Brickman Hex acts with {beta}-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal Development, September 15, 2006; 133(18): 3709 - 3722. [Abstract] [Full Text] [PDF]

				W. V. Cardoso and J. Lu Regulation of early lung morphogenesis: questions, facts and controversies Development, May 1, 2006; 133(9): 1611 - 1624. [Abstract] [Full Text] [PDF]

				S. Tada, T. Era, C. Furusawa, H. Sakurai, S. Nishikawa, M. Kinoshita, K. Nakao, T. Chiba, and S.-I. Nishikawa Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture Development, October 1, 2005; 132(19): 4363 - 4374. [Abstract] [Full Text] [PDF]

				A. Kubo, V. Chen, M. Kennedy, E. Zahradka, G. Q. Daley, and G. Keller The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiation Blood, June 15, 2005; 105(12): 4590 - 4597. [Abstract] [Full Text] [PDF]

				R. Zhao, A. J. Watt, J. Li, J. Luebke-Wheeler, E. E. Morrisey, and S. A. Duncan GATA6 Is Essential for Embryonic Development of the Liver but Dispensable for Early Heart Formation Mol. Cell. Biol., April 1, 2005; 25(7): 2622 - 2631. [Abstract] [Full Text] [PDF]

				M. Djavani, I. Topisirovic, J. C. Zapata, M. Sadowska, Y. Yang, J. Rodas, I. S. Lukashevich, C. W. Bogue, C. D. Pauza, K. L. B. Borden, et al. The Proline-Rich Homeodomain (PRH/HEX) Protein Is Down-Regulated in Liver during Infection with Lymphocytic Choriomeningitis Virus J. Virol., February 15, 2005; 79(4): 2461 - 2473. [Abstract] [Full Text] [PDF]

				A. C. Foley and M. Mercola Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex Genes & Dev., February 1, 2005; 19(3): 387 - 396. [Abstract] [Full Text] [PDF]

				H. Hallaq, E. Pinter, J. Enciso, J. McGrath, C. Zeiss, M. Brueckner, J. Madri, H. C. Jacobs, C. M. Wilson, H. Vasavada, et al. A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels Development, October 15, 2004; 131(20): 5197 - 5209. [Abstract] [Full Text] [PDF]

				A. A. Rana, J. P. M. Barbera, T. A. Rodriguez, D. Lynch, E. Hirst, J. C. Smith, and R. S. P. Beddington Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates Development, October 15, 2004; 131(20): 4999 - 5007. [Abstract] [Full Text] [PDF]

				M. De Felice and R. Di Lauro Thyroid Development and Its Disorders: Genetics and Molecular Mechanisms Endocr. Rev., October 1, 2004; 25(5): 722 - 746. [Abstract] [Full Text] [PDF]

				T. E. Swingler, K. L. Bess, J. Yao, S. Stifani, and P.-S. Jayaraman The Proline-rich Homeodomain Protein Recruits Members of the Groucho/Transducin-like Enhancer of Split Protein Family to Co-repress Transcription in Hematopoietic Cells J. Biol. Chem., August 13, 2004; 279(33): 34938 - 34947. [Abstract] [Full Text] [PDF]

				G. C. Chu, N. R. Dunn, D. C. Anderson, L. Oxburgh, and E. J. Robertson Differential requirements for Smad4 in TGF{beta}-dependent patterning of the early mouse embryo Development, August 1, 2004; 131(15): 3501 - 3512. [Abstract] [Full Text] [PDF]

				N. R. Dunn, S. D. Vincent, L. Oxburgh, E. J. Robertson, and E. K. Bikoff Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo Development, April 15, 2004; 131(8): 1717 - 1728. [Abstract] [Full Text] [PDF]

				A. Kubo, K. Shinozaki, J. M. Shannon, V. Kouskoff, M. Kennedy, S. Woo, H. J. Fehling, and G. Keller Development of definitive endoderm from embryonic stem cells in culture Development, April 1, 2004; 131(7): 1651 - 1662. [Abstract] [Full Text] [PDF]

				H. Yoshitomi and K. S. Zaret Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a Development, February 15, 2004; 131(4): 807 - 817. [Abstract] [Full Text] [PDF]

				R. Bort, J. P. Martinez-Barbera, R. S. P. Beddington, and K. S. Zaret Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas Development, February 15, 2004; 131(4): 797 - 806. [Abstract] [Full Text] [PDF]

				S. Kasamatsu, A. Sato, T. Yamamoto, V. W. Keng, H. Yoshida, Y. Yamazaki, M. Shimoda, J.-i. Miyazaki, and T. Noguchi Identification of the Transactivating Region of the Homeodomain Protein, Hex J. Biochem., February 1, 2004; 135(2): 217 - 223. [Abstract] [Full Text] [PDF]

				A. Sato, V. W. Keng, T. Yamamoto, S. Kasamatsu, T. Ban, H. Tanaka, S.-i. Satoh, K. Yamada, and T. Noguchi Identification and Characterization of the Hematopoietic Cell-Specific Enhancer-Like Element of the Mouse Hex Gene J. Biochem., February 1, 2004; 135(2): 259 - 268. [Abstract] [Full Text] [PDF]

				P. P. L. Tam and J. Rossant Mouse embryonic chimeras: tools for studying mammalian development Development, December 22, 2003; 130(25): 6155 - 6163. [Abstract] [Full Text] [PDF]

				I. Topisirovic, M. L. Guzman, M. J. McConnell, J. D. Licht, B. Culjkovic, S. J. Neering, C. T. Jordan, and K. L. B. Borden Aberrant Eukaryotic Translation Initiation Factor 4E-Dependent mRNA Transport Impedes Hematopoietic Differentiation and Contributes to Leukemogenesis Mol. Cell. Biol., December 15, 2003; 23(24): 8992 - 9002. [Abstract] [Full Text] [PDF]

				C. Haumaitre, M. Reber, and S. Cereghini Functions of HNF1 Family Members in Differentiation of the Visceral Endoderm Cell Lineage J. Biol. Chem., October 17, 2003; 278(42): 40933 - 40942. [Abstract] [Full Text] [PDF]

				Y. Guo, R. Chan, H. Ramsey, W. Li, X. Xie, W. C. Shelley, J. P. Martinez-Barbera, B. Bort, K. Zaret, M. Yoder, et al. The homeoprotein Hex is required for hemangioblast differentiation Blood, October 1, 2003; 102(7): 2428 - 2435. [Abstract] [Full Text] [PDF]

				I. del Barco Barrantes, G. Davidson, H.-J. Grone, H. Westphal, and C. Niehrs Dkk1 and noggin cooperate in mammalian head induction Genes & Dev., September 15, 2003; 17(18): 2239 - 2244. [Abstract] [Full Text] [PDF]

				S. D. Vincent, N. R. Dunn, S. Hayashi, D. P. Norris, and E. J. Robertson Cell fate decisions within the mouse organizer are governed by graded Nodal signals Genes & Dev., July 1, 2003; 17(13): 1646 - 1662. [Abstract] [Full Text] [PDF]