Molecular analysis of external genitalia formation: the role of fibroblast growth factor (Fgf) genes during genital tubercle formation

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Anderson, C. A. and Clark, R. L (1990). External genitalia of the rat: normal development and the histogenesis of 5 alpha-reductase inhibitor-induced abnormalities. Teratology 42, 483-496.[Medline]

Arman, E., Haffner-Krausz, R., Chen, Y., Heath, J. K. and Lonai, P (1998). Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc. Natl. Acad. Sci. USA 95, 5082-5087.[Abstract/Free Full Text]

Arman, E., Haffner-Krausz, R., Gorivodsky, M. and Lonai, P (1999). Fgfr2 is required for limb outgrowth and lung-branching morphogenesis. Proc. Natl. Acad. Sci. USA 96, 11895-11899.[Abstract/Free Full Text]

Bei, M. and Maas, R (1998). FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development. Development 125, 4325-4333.[Abstract]

Bellusci, S., Grindley, J., Emoto, H., Itoh, N. and Hogan, B. L (1997). Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 124, 4867-4878.[Abstract]

Belo, J. A., Leyns, L., Yamada, G. and De Robertis, E. M (1998). The prechordal midline of the chondrocranium is defective in Goosecoid-1 mouse mutants. Mech. Dev 72, 15-25.[Medline]

Bitgood, M. J. and McMahon, A. P (1995). Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol 172, 126-138.[Medline]

Chisaka, O., Musci, T. S. and Capecchi, M. R (1992). Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6. Nature 355, 516-520.[Medline]

Cohn, M. J., Izpisua-Belmonte, J. C., Abud, H., Heath, J. K. and Tickle, C (1995). Fibroblast growth factors induce additional limb development from the flank of chick embryos. Cell 80, 739-746.[Medline]

Cohn, M. J. and Tickle, C (1996). Limbs: a model for pattern formation within the vertebrate body plan. Trends Genet 12, 253-257.[Medline]

Crossley, P. H. and Martin, G. R (1995). The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.[Abstract]

Crossley, P. H., Martinez, S. and Martin, G. R (1996). Midbrain development induced by FGF8 in the chick embryo. Nature 380, 66-68.[Medline]

Crossley, P. H., Minowada, G., MacArthur, C. A. and Martin, G. R (1996). Roles for FGF8 in the induction, initiation, and maintenance of chick limb development. Cell 84, 127-136.[Medline]

Cunha, G. R. and Chung, L. W (1981). Stromal-epithelial interactions. I. Induction of prostatic phenotype in urothelium of testicular feminized (Tfm/y) mice. J. Steroid Biochem 14, 1317-1324.[Medline]

Cunha, G. R., Fujii, H., Neubauer, B. L., Shannon, J. M., Sawyer, L. and Reese, B. A (1983). Epithelial-mesenchymal interactions in prostatic development. I. morphological observations of prostatic induction by urogenital sinus mesenchyme in epithelium of the adult rodent urinary bladder. J. Cell Biol 96, 1662-1670.[Abstract/Free Full Text]

Cunha, G. R. and Lung, B (1978). The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wild-type and androgen-insensitive (Tfm) mice. J. Exp. Zool 205, 181-193.[Medline]

Dassule, H. R. and McMahon, A. P (1998). Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev. Biol 202, 215-227.[Medline]

De Moerlooze, L., Spencer-Dene, B., Revest, J., Hajihosseini, M., Rosewell, I. and Dickson, C (2000). An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development 127, 483-492.[Abstract]

Dolle, P., Izpisua-Belmonte, J. C., Brown, J. M., Tickle, C. and Duboule, D (1991). HOX-4 genes and the morphogenesis of mammalian genitalia. Genes Dev 5, 1767-1767.[Abstract/Free Full Text]

Dorkin, T. J., Robinson, M. C., Marsh, C., Bjartell, A., Neal, D. E. and Leung, H. Y (1999). FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease. Oncogene 18, 2755-2761.[Medline]

Duboule, D (1993). The function of Hox genes in the morphogenesis of the vertebrate limb. Ann. Genet 36, 24-29.[Medline]

Duboule, D (1994). How to make a limb?. Science 266, 575-576.[Free Full Text]

Gehring, W. J., Affolter, M. and Burglin, T (1994). Homeodomain proteins. Annu. Rev. Biochem 63, 487-526.[Medline]

Goff, D. J. and Tabin, C. J (1996). Hox mutations au naturel. Nat. Genet 13, 256-258.[Medline]

Grenister, T.W (1954). The origin and fate of the urethral plate in man. J. Anat 88, 413-424.

Hall, B. K (1981). The induction of neural crest-derived cartilage and bone by embryonic epithelia: an analysis of the mode of action of an epithelial-mesenchymal interaction. J. Embryol. Exp. Morph 64, 305-320.[Medline]

Hayward, S. W., Haughney, P. C., Rosen, M. A., Greulich, K. M., Weier, H. U., Dahiya, R. and Cunha, G. R (1998). Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model. Differentiation 63, 131-140.[Medline]

Hogan, B. L (1996). Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10, 1580-1594.[Free Full Text]

Hogan, B. L (1999). Morphogenesis. Cell 96, 225-233.[Medline]

Iseki, S., Wilkie, A. O. and Morriss-Kay, G. M (1999). Fgfr1 and fgfr2 have distinct differentiation-and proliferation-related roles in the developing mouse skull vault [In Process Citation]. Development 126, 5611-5620.[Abstract]

Johnson, D. E. and Williams, L. T (1993). Structural and functional diversity in the FGF receptor multigene family. Adv. Cancer Res 60, 1-41.[Medline]

Johnson, R. L. and Tabin, C. J (1997). Molecular models for vertebrate limb development. Cell 90, 979-990.[Medline]

Jones, C. M., Lyons, K. M. and Hogan, B. L (1991). Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse. Development 111, 531-542.[Abstract]

Jung, J., Zheng, M., Goldfarb, M. and Zaret, K. S (1999). Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science 284, 1998-2003.[Abstract/Free Full Text]

Kessel, M. and Gruss, P (1990). Murine developmental control genes. Science 249, 374-379.[Abstract/Free Full Text]

Kondo, T., Zakany, J. and Duboule, D (1998). Control of colinearity in AbdB genes of the mouse HoxD complex. Molec. Cell 1, 289-300.

Kondo, T., Zakany, J., Innis, J. W. and Duboule, D (1997). Of fingers, toes and penises. Nature 390, 29-.[Medline]

Kurzrock, E. A., Baskin, L. S. and Cunha, G. R (1999). Ontogeny of the male urethra: theory of endodermal differentiation. Differentiation 64, 115-122.[Medline]

Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A. and Tabin, C (1994). Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.[Medline]

Le Douarin, N. M. and Jotereau, F. V (1975). Tracing of cells of the avian thymus through embryonic life in interspecific chimeras. J. Exp. Med 142, 17-40.[Abstract/Free Full Text]

Lebeche, D., Malpel, S. and Cardoso, W. V (1999). Fibroblast growth factor interactions in the developing lung. Mech. Dev 86, 125-136.[Medline]

Lee, S. M., Danielian, P. S., Fritzsch, B. and McMahon, A. P (1997). Evidence that FGF8 signalling from the midbrain-hindbrain junctionregulates growth and polarity in the developing midbrain. Development 124, 959-969.[Abstract]

Lewandoski, M., Meyers, E. N. and Martin, G. R (1997). Analysis of Fgf8 gene function in vertebrate development. Cold Spring Harb. Symp. Quant. Biol 62, 159-168.[Abstract/Free Full Text]

MacKenzie, A., Ferguson, M. W. and Sharpe, P. T (1992). Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape. Development 115, 403-420.[Abstract]

Martin, G. R (1998). The roles of FGFs in the early development of vertebrate limbs. Genes Dev 12, 1571-1586.[Free Full Text]

Meyers, E. N., Lewandoski, M. and Martin, G. R (1998). An Fgf8 mutant allelic series generated by Cre-and Flp-mediated recombination. Nat. Genet 18, 136-141.[Medline]

Min, H., Danilenko, D. M., Scully, S. A., Bolon, B., Ring, B. D., Tarpley, J. E., DeRose, M. and Simonet, W. S (1998). Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev 12, 3156-3161.[Abstract/Free Full Text]

Moon, A. M., Boulet, A. M. and Capecchi, M. R (2000). Normal limb development in conditional mutants of Fgf4. Development 127, 989-996.[Abstract]

Mortlock, D. P. and Innis, J. W (1997). Mutation of HOXA13 in hand-foot-genital syndrome. Nat. Genet 15, 179-180.[Medline]

Murakami, R (1987). A histological study of the development of the penis of wild-type and androgen-insensitive mice. J. Anat 153, 223-231.[Medline]

Murakami, R. and Mizuno, T (1986). Proximal-distal sequence of development of the skeletal tissues in the penis of rat and the inductive effect of epithelium. J. Embryol. Exp. Morph 92, 133-143.[Medline]

Murakami, R., Takeda, H., Yamaoka, I. and Sakakura, T (1990). Close correlation between the distribution of tenascin and that of actin filaments in the mouse urethral mesenchyme during active morphogenesis. Acta Anat 138, 128-131.[Medline]

Neubuser, A., Peters, H., Balling, R. and Martin, G. R (1997). Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation. Cell 90, 247-255.[Medline]

Niswander, L (1999). Developmental biology. Legs to wings and back again. Nature 398, 751-752.[Medline]

Niswander, L., Jeffrey, S., Martin, G. R. and Tickle, C (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.[Medline]

Niswander, L. and Martin, G. R (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.[Abstract]

Niswander, L., Tickle, C., Vogel, A., Booth, I. and Martin, G. R (1993). FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75, 579-587.[Medline]

Nordenskjold, A., Friedman, E., Tapper-Persson, M., Soderhall, C., Leviav, A., Svensson, J. and Anvret, M (1999). Screening for mutations in candidate genes for hypospadias. Urol. Res 27, 49-55.[Medline]

Oefelein, M., Chin-Chance, C. and Bushman, W (1996). Expression of the homeotic gene Hox-d13 in the developing and adult mouse prostate. J. Urol 155, 342-346.[Medline]

Ohuchi, H., Nakagawa, T., Yamamoto, A., Araga, A., Ohata, T., Ishimaru, Y., Yoshioka, H., Kuwana, T., Nohno, T., Yamasaki, M (1997). The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor. Development 124, 2235-2244.[Abstract]

Ohuchi, H., Yoshioka, H., Tanaka, A., Kawakami, Y., Nohno, T. and Noji, S (1994). Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis. Biochem. Biophys. Res. Commun 204, 882-888.[Medline]

Ornitz, D. M (2000). FGFs, heparan sulfate and FGFRs: complex interactions essential for development. BioEssays 22, 108-112.[Medline]

Partanen, J., Schwartz, L. and Rossant, J (1998). Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos. Genes Dev 12, 2332-2344.[Abstract/Free Full Text]

Pizette, S. and Niswander, L (1999). BMPs negatively regulate structure and function of the limb apical ectodermal ridge. Development 126, 883-894.[Abstract]

Podlasek, C. A., Barnett, D. H., Clemens, J. Q., Bak, P. M. and Bushman, W (1999). Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium. Dev. Biol 209, 28-39.[Medline]

Roberts, D. J., Johnson, R. L., Burke, A. C., Nelson, C. E., Morgan, B. A. and Tabin, C (1995). Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development 121, 3163-3174.[Abstract]

Rudnicki, M. A., Schnegelsberg, P. N., Stead, R. H., Braun, T., Arnold, H. H. and Jaenisch, R (1993). MyoD or Myf-5 is required for the formation of skeletal muscle. Cell 75, 1351-1359.[Medline]

Satokata, I. and Maas, R (1994). Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nat. Genet 6, 348-356.[Medline]

Sekine, K., Ohuchi, H., Fujiwara, M., Yamasaki, M., Yoshizawa, T., Sato,T., Yagishita, N., Matsui, D., Koga, Y., Itoh, N. et al (1999). Fgf10is essential for limb and lung formation. Nat. Genet 21, 138-141.[Medline]

Slavkin, H. C., Snead, M. L., Zeichner-David, M., Jaskoll, T. F. and Smith, B. T (1984). Concepts of epithelial-mesenchymal interactions during development: tooth and lung organogenesis. J. Cell Biochem 26, 117-125.[Medline]

Sun, X., Meyers, E. N., Lewandoski, M. and Martin, G. R (1999). Targeted disruption of fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev 13, 1834-1846.[Abstract/Free Full Text]

Sutherland, R. W., Wiener, J. S., Hicks, J. P., Marcelli, M., Gonzales, E. T., Jr., Roth, D. R. and Lamb, D. J (1996). Androgen receptor gene mutations are rarely associated with isolated penile hypospadias. J. Urol 156, 828-831.[Medline]

Tabin, C (1995). The initiation of the limb bud: growth factors, Hox genes, and retinoids. Cell 80, 671-674.[Medline]

Tabin, C. J (1991). Retinoids, homeoboxes, and growth factors: toward molecular models for limb development. Cell 66, 199-217.[Medline]

Tam, P. P (1989). Regionalisation of the mouse embryonic ectoderm: allocation of prospective ectodermal tissues during gastrulation. Development 107, 55-67.[Abstract]

Thesleff, I., Partanen, A. M. and Vainio, S (1991). Epithelial-mesenchymal interactions in tooth morphogenesis: the roles of extracellular matrix, growth factors, and cell surface receptors. J. Craniofac. Genet. Dev. Biol 11, 229-237.[Medline]

Thesleff, I., Vaahtokari, A. and Partanen, A. M (1995). Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs. Int. J. Dev. Biol 39, 35-50.[Medline]

Thomson, A. A. and Cunha, G. R (1999). Prostatic growth and development are regulated by FGF10. Development 126, 3693-3701.[Abstract]

Tickle, C. and Eichele, G (1994). Vertebrate limb development. Annu. Rev. Cell Biol 10, 121-152.

Trumpp, A., Depew, M. J., Rubenstein, J. L., Bishop, J. M. and Martin, G. R (1999). Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. Genes Dev 13, 3136-3148.[Abstract/Free Full Text]

Tucker, A. S., Yamada, G., Grigoriou, M., Pachnis, V. and Sharpe, P. T (1999). Fgf-8 determines rostral-caudal polarity in the first branchial arch. Development 126, 51-61.[Abstract]

Wall, N. A. and Hogan, B. L (1995). Expression of bone morphogenetic protein-4 (BMP-4), bone morphogenetic protein-7 (BMP-7), fibroblast growth factor-8 (FGF-8) and sonic hedgehog (SHH) during branchial arch development in the chick. Mech. Dev 53, 383-392.[Medline]

Warot, X., Fromental-Ramain, C., Fraulob, V., Chambon, P. and Dolle, P (1997). Gene dosage-dependent effects of the Hoxa-13 and Hoxd-13 mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts. Development 124, 4781-4791.[Abstract]

Xu, X., Weinstein, M., Li, C., Naski, M., Cohen, R. I., Ornitz, D. M., Leder, P. and Deng, C (1998). Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development 125, 753-765.[Abstract]

Yamaguchi, T. P., Bradley, A., McMahon, A. P. and Jones, S (1999). A wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 126, 1211-1223.[Abstract]

Yamasaki, M., Miyake, A., Tagashira, S. and Itoh, N (1996). Structure and expression of the rat mRNA encoding a novel member of the fibroblast growth factor family. J. Biol. Chem 271, 15918-15921.[Abstract/Free Full Text]

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				S. Miyagawa, Y. Satoh, R. Haraguchi, K. Suzuki, T. Iguchi, M. M. Taketo, N. Nakagata, T. Matsumoto, K.-i. Takeyama, S. Kato, et al. Genetic Interactions of the Androgen and Wnt/{beta}-Catenin Pathways for the Masculinization of External Genitalia Mol. Endocrinol., June 1, 2009; 23(6): 871 - 880. [Abstract] [Full Text] [PDF]

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				A. Petiot, C. L. Perriton, C. Dickson, and M. J. Cohn Development of the mammalian urethra is controlled by Fgfr2-IIIb Development, May 15, 2005; 132(10): 2441 - 2450. [Abstract] [Full Text] [PDF]

				M. Plikus, W. P. Wang, J. Liu, X. Wang, T.-X. Jiang, and C.-M. Chuong Morpho-Regulation of Ectodermal Organs: Integument Pathology and Phenotypic Variations in K14-Noggin Engineered Mice through Modulation of Bone Morphogenic Protein Pathway Am. J. Pathol., March 1, 2004; 164(3): 1099 - 1114. [Abstract] [Full Text] [PDF]

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				M. Sawaki, S. Noda, T. Muroi, H. Mitoma, S. Takakura, S. Sakamoto, and K. Yamasaki In Utero through Lactational Exposure to Ethinyl Estradiol Induces Cleft Phallus and Delayed Ovarian Dysfunction in the Offspring Toxicol. Sci., October 1, 2003; 75(2): 402 - 411. [Abstract] [Full Text] [PDF]

				E. A. Morgan, S. B. Nguyen, V. Scott, and H. S. Stadler Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia Development, July 15, 2003; 130(14): 3095 - 3109. [Abstract] [Full Text] [PDF]

				E. A. Packham and J. D. Brook T-box genes in human disorders Hum. Mol. Genet., April 2, 2003; 12(90001): R37 - 44. [Abstract] [Full Text] [PDF]

				H. Harada, T. Toyono, K. Toyoshima, M. Yamasaki, N. Itoh, S. Kato, K. Sekine, and H. Ohuchi FGF10 maintains stem cell compartment in developing mouse incisors Development, March 5, 2003; 129(6): 1533 - 1541. [Abstract] [Full Text] [PDF]

				R. Haraguchi, R. Mo, C.-c. Hui, J. Motoyama, S. Makino, T. Shiroishi, W. Gaffield, and G. Yamada Unique functions of Sonic hedgehog signaling during external genitalia development Development, November 1, 2001; 128(21): 4241 - 4250. [Abstract] [Full Text] [PDF]

				W.-S. Lee, F. Otsuka, R. K. Moore, and S. Shimasaki Effect of Bone Morphogenetic Protein-7 on Folliculogenesis and Ovulation in the Rat Biol Reprod, October 1, 2001; 65(4): 994 - 999. [Abstract] [Full Text] [PDF]

				J. A. McLachlan Environmental Signaling: What Embryos and Evolution Teach Us About Endocrine Disrupting Chemicals Endocr. Rev., June 1, 2001; 22(3): 319 - 341. [Abstract] [Full Text] [PDF]