Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Kwong, W. Y.
	Articles by Fleming, T. P.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Kwong, W. Y.
	Articles by Fleming, T. P.


Social Bookmarking

	What's this?

Barnes, F. L (2000). The effects of the early uterine environment on the subsequent development of embryo and fetus. Theriogenology 53, 649-658.[Medline]

Breier, B. H., Gallaher, B. W. and Gluckman, P. D (1991). Radioimmunoassay for insulin-like growth factor-1: solutions to some potential problems and pitfalls. J. Endocrinol 128, 347-357.[Abstract/Free Full Text]

Brison, D. R. and Schultz, R. M (1997). Apoptosis during mouse blastocyst formation: evidence for the role for survival factors including transforming growth factor. Biol. Reprod 56, 1088-1096.[Abstract]

Dean, W., Bowden, L., Aitchison, A., Klose, J., Moore, T., Meneses, J. J., Reik, W. and Feil, R (1998). Altered imprinted gene methylation and expression in completely ES cell-derived mouse fetuses: association with aberrant phenotypes. Development 125, 2273-2282.[Abstract]

Desai M., Crowther, N. J., Lucas, A. and Hales, C. N (1996). Organ-selective growth in the offspring of protein-restricted mothers. Br. J. Nutr 76, 591-603.[Medline]

Edirisinghe, W. R., Wales, R. G. and Pike, I. L (1984). Degradation of biochemical pools labelled with [14C]glucose during culture of 8-cell andmorula-early blastocyst-stage mouse embryos in vitro and in vivo. J. Reprod. Fertil 72, 59-65.[Abstract/Free Full Text]

Edwards, C. R., Benediktsson, R., Lindsay, R. S. and Seckl, J. R (1993). Dysfunction of placental glucocorticoid barrier: link between foetal environment and adult hypertension?. Lancet 341, 355-357.[Medline]

Erickson, R. P (1997). Does sex determination start at conception?. BioEssays 19, 1027-1032.[Medline]

Fleming, J. V., Fontanier, N., Harries, D. N. and Rees, W. D (1997). The growth arrest genes gas5, gas6, and CHOP-10 (gadd153) are expressed in the mouse preimplantation embryo. Mol. Reprod. Dev 48, 310-316.[Medline]

Fleming, J. V., Hay, S. M., Harries, D. N. and Rees, W. D (1998). Effect of nutrient deprivation on the expression of growth-arrest genes ( gas and gadd ) in F9 embryonal carcinoma cells. Biochem. J 330, 573-579.

Fleming, T. P (1987). A quantitative analysis of cell allocation to trophectoderm and inner cell mass in the mouse blastocyst. Dev. Biol 119, 520-531.[Medline]

Gallaher, B. W., Brier, B. H., Keven, C. L., Harding, J. E. and Gluckman, P. D (1998). Foetal programming of insulin-like growth factor (IGF)-1 and IGF-binding protein-3: evidence for an altered response to undernutrition in late gestation following exposure to periconceptual undernutrition in the sheep. J. Endocrinol 159, 501-508.[Abstract]

Handyside, A. H. and Hunter, S (1984). A rapid procedure for visualizing the inner cell mass and trophectoderm nuclei of mouse blastocysts in situ using polynucleotide-specific fluorochromes. J. Exp. Zool 31, 429-434.

Hishinuma, M., Takahashi, Y. and Kanagawa, H (1996). Post-implantation development of demi-embryos and induction of decidual cell reaction in mice. Theriogenology 46, 1187-1200.

Johnson, M. H. and Nasr-Esfahani, M. H (1994). Radical solutions and cultural problems: could free oxygen radicals be responsible for the impaired development of preimplantation mammalian embryos in vitro?. BioEssays 16, 31-38.[Medline]

Kaye, P. L., Bell, K. L., Beebe, L. F. S., Dunglison, G. F., Gardner, H. G. and Harvey, M. B (1992). Insulin and IGFs in preimplantation development. Reprod. Fertil. Dev 65, 373-386.

Kaye, P. L. and Gardner, H. G (1999). Preimplantation access to maternal insulin and albumin increases foetal growth rate in mice. Hum. Reprod 14, 3052-3059.[Abstract/Free Full Text]

Kramer, B., Magan, A. and De Wet, G (1993). Hyperstimulation affects vascular permeability at implantation sites in the rat endometrium. J. Assist. Reprod. Genet 10, 163-167.[Medline]

Lamb, V. K. and Leese, H. J (1994). Uptake of a mixture of amino acids by mouse blastocysts. J. Reprod. Fert 102, 169-175.[Abstract/Free Full Text]

Lane, M. and Gardner, D. K (1997). Differential regulation of mouse embryo development and viability by amino acids. J. Reprod. Fertil 109, 153-164.[Abstract/Free Full Text]

Langley, S. C. and Jackson, A. A (1994). Increased systolic blood pressure in adult rats induced by foetal exposure to maternal low protein diet. Clin. Sci 86, 217-222.[Medline]

Langley-Evans, S. C (2000). Critical differences between two low protein diet protocols in the programming of hypertension in the rat. Int. J. Food Sci. Nutr 51, 11-17.[Medline]

Langley-Evans, S. C. and Nwagwu, M (1998). Impaired growth and increased glucocorticoid-sensitive enzyme activities in tissues of rat fetuses exposed to maternal low protein diets. Life Sci 63, 605-615.[Medline]

Langley-Evans, S. C., Welham, S. J. M., Sherman, R. C. and Jackson, A. A (1996). Weanling rats exposed to maternal low-protein diets during discrete periods of gestation exhibit differing severity of hypertension. Clin. Sci 91, 607-615.[Medline]

Langley-Evans, S. C., Sherman, R. C., Welham, S. J. M., Nwagwu, M. O., Gardner, D. S. and Jackson, A. A (1999). Intrauterine programming of hypertension: the role of the renin-angiotensin system. Biochem. Soc. Trans 27, 88-93.[Medline]

Lea, R. G., McCracken, J. E., McIntyre, S. S., Smith, W. and Baird, J (1996). Disturbed development of the preimplantation embryo in the insulin-dependent diabetic BB/E rat. Diabetes 45, 1463-1470.[Abstract]

Leese, H. J., Donnay, I. and Thompson, J. G (1998). Human assisted conception: a cautionary tale. Lessons from domestic animals. Hum. Reprod 13, 4-.

Moley, K. H., Chi, M. M. Y., Manchester, J. K., McDougal, D. B. and Lowry, O. H (1996). Alterations of intraembryonic metabolites in preimplantation mouse embryos exposed to elevated concentrations of glucose: a metabolic explanation for the developmental retardation seen in preimplantation embryos from diabetic animals. Biol. Reprod 54, 1209-1216.[Abstract]

Munoz, G. and Bongiorni-Malave I (1979). Influence of dietary protein restriction on ovulation, fertilization rates and pre-implantation development in mice. J. Exp. Zool 210, 253-258.[Medline]

Pampfer, S., Vanderheyden, I., McCracken, J. E., Vesela, J. and De Hertogh, R (1997). Increased cell death in rat blastocysts exposed to maternal diabetes in utero and to high glucose or tumour necrosis factor- in vitro. Development 124, 4827-4836.[Abstract]

Power, M. A. and Tam, P. P. L (1993). Onset of gastrulation, morphogenesis and somitogenesis in mouse embryos displaying compensatory growth. Anat. Embryol 187, 493-504.[Medline]

Rees, W. D., Hay, S. M., Buchan, V., Antipatis, C. and Palmer, R. M (1999). The effect of maternal protein restriction on the growth of the rat fetus and its amino acid supply. Br. J. Nutrition 81, 243-250.[Medline]

Reik, W., Romer, I., Barton, S. C., Surani, M. A., Howlett, S. K. and Klose, J (1993). Adult phenotype in the mouse can be affected by epigenetic events in the early embryo. Development 119, 933-942.[Abstract/Free Full Text]

Seckl, J. R., Nyirenda, M. J., Walker, B. R. and Chapman, K. E (1999). Glucocorticoids and foetal programming. Biochem. Soc. Trans 27, 74-78.[Medline]

Sheth, B., Fesenko, I., Collins, J. E., Moran, B., Wild, A. E. and Fleming, T. P (1997). Tight junction assembly during mouse blastocyst formation is regulated by late expression of ZO-1+ isoform. Development 124, 2027-2037.[Abstract]

Sinclair, K. D., McEvoy, T. G., Maxfield, E. K., Matlin, C. A., Young, L. E., Wilmut, I., Broadbent, P. J. and Robinson, J. J (1999). Aberrant foetal growth and development after in vitro culture of sheep zygotes. J. Reprod. Fertil 116, 177-186.[Abstract/Free Full Text]

Stoddart, N. R., Wild, A. E. and Fleming, T. P (1996). Stimulation of development in vitro by platelet activating factor receptor ligands released by mouse pre-implantation embryos. J. Reprod. Fertil 108, 47-53.[Abstract/Free Full Text]

Tam, P. P. L (1988). Postimplantation development of mitomycin-C treated mouse blastocysts. Teratology 37, 205-212.[Medline]

Thompson, J. G., Gardner, D. K., Pugh, P. A., McMillan, W. H. and Tervit, H. R (1995). Lamb birth-weight is affected by culture system utilized during in-vitro pre-elongation development of ovine embryos. Biol. Reprod 53, 1385-1391.[Abstract]

Walker, S. K., Hartwich, K. M. and Seamark, R. F (1996). The production of unusually large offspring following embryo manipulation: concepts and challenges. Theriogenology 45, 111-120.

Wrenzycki, C., Herrmann, D, Carnwath, J. W. and Niemann, H (1999). Alterations in the relative abundance of gene transcripts in preimplantation bovine embryos cultured in medium supplemented with either serum or PVA. Mol. Reprod. Dev 53, 8-18.[Medline]

Wynn, M. and Wynn, A (1988). Nutrition around conception and the prevention of low birthweight. Nutr. Health 6, 37-52.[Medline]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

K. L. Connor, J. R. G. Challis, P. van Zijl, C. W. Rumball, S. Alix, A. L. Jaquiery, M. H. Oliver, J. E. Harding, and F. H. Bloomfield
Do Alterations in Placental 11{beta}-Hydroxysteroid Dehydrogenase (11{beta}HSD) Activities Explain Differences in Fetal Hypothalamic-Pituitary-Adrenal (HPA) Function Following Periconceptional Undernutrition or Twinning in Sheep?
Reproductive Sciences, December 1, 2009; 16(12): 1201 - 1212.
[Abstract] [PDF]

S. R. Milligan, W. V. Holt, and R. Lloyd
Impacts of climate change and environmental factors on reproduction and development in wildlife
Phil Trans R Soc B, November 27, 2009; 364(1534): 3313 - 3319.
[Abstract] [Full Text] [PDF]

C. Torrens, T. H. Snelling, R. Chau, M. Shanmuganathan, J. K. Cleal, K. R. Poore, D. E. Noakes, L. Poston, M. A. Hanson, and L. R. Green
Effects of pre- and periconceptional undernutrition on arterial function in adult female sheep are vascular bed dependent
Exp Physiol, September 1, 2009; 94(9): 1024 - 1033.
[Abstract] [Full Text] [PDF]

E. S. Lucas, S. L. Finn, A. Cox, F. R. Lock, and A. J. Watkins
The impact of maternal high fat nutrition on the next generation: food for thought?
J. Physiol., July 15, 2009; 587(14): 3425 - 3426.
[Full Text] [PDF]

I. Cetin, C. Berti, and S. Calabrese
Role of micronutrients in the periconceptional period
Hum. Reprod. Update, June 30, 2009; (2009) dmp025v1.
[Abstract] [Full Text] [PDF]

C. E. Bell, N. M.K. Lariviere, P. H. Watson, and A. J. Watson
Mitogen-activated protein kinase (MAPK) pathways mediate embryonic responses to culture medium osmolarity by regulating Aquaporin 3 and 9 expression and localization, as well as embryonic apoptosis
Hum. Reprod., June 1, 2009; 24(6): 1373 - 1386.
[Abstract] [Full Text] [PDF]

Z. Wang, Z. Huang, G. Lu, L. Lin, and M. Ferrari
Hypoxia during pregnancy in rats leads to early morphological changes of atherosclerosis in adult offspring
Am J Physiol Heart Circ Physiol, May 1, 2009; 296(5): H1321 - H1328.
[Abstract] [Full Text] [PDF]

J.J. Eppig, M.J. O'Brien, K. Wigglesworth, A. Nicholson, W. Zhang, and B.A. King
Effect of in vitro maturation of mouse oocytes on the health and lifespan of adult offspring
Hum. Reprod., April 1, 2009; 24(4): 922 - 928.
[Abstract] [Full Text] [PDF]

M. Mitchell, S. L. Schulz, D. T. Armstrong, and M. Lane
Metabolic and Mitochondrial Dysfunction in Early Mouse Embryos Following Maternal Dietary Protein Intervention
Biol Reprod, April 1, 2009; 80(4): 622 - 630.
[Abstract] [Full Text] [PDF]

D. M. Burrage, L. Braddick, J. K. Cleal, P. Costello, D. E. Noakes, M. A. Hanson, and L. R. Green
The late gestation fetal cardiovascular response to hypoglycaemia is modified by prior peri-implantation undernutrition in sheep
J. Physiol., February 1, 2009; 587(3): 611 - 624.
[Abstract] [Full Text] [PDF]

M. Ceelen, M. M. van Weissenbruch, J. P.W. Vermeiden, F. E. van Leeuwen, and H. A. Delemarre-van de Waal
Pubertal development in children and adolescents born after IVF and spontaneous conception
Hum. Reprod., December 1, 2008; 23(12): 2791 - 2798.
[Abstract] [Full Text] [PDF]

J. S. Gilbert and M. J. Nijland
Sex differences in the developmental origins of hypertension and cardiorenal disease
Am J Physiol Regulatory Integrative Comp Physiol, December 1, 2008; 295(6): R1941 - R1952.
[Abstract] [Full Text] [PDF]

H. D. Morgan, X. L. Jin, A. Li, E. Whitelaw, and C. O'Neill
The Culture of Zygotes to the Blastocyst Stage Changes the Postnatal Expression of an Epigentically Labile Allele, Agouti Viable Yellow, in Mice
Biol Reprod, October 1, 2008; 79(4): 618 - 623.
[Abstract] [Full Text] [PDF]

P. D. Gluckman, M. A. Hanson, C. Cooper, and K. L. Thornburg
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
N. Engl. J. Med., July 3, 2008; 359(1): 61 - 73.
[Full Text] [PDF]

M. Ceelen, M. M. van Weissenbruch, J. P. W. Vermeiden, F. E. van Leeuwen, and H. A. Delemarre-van de Waal
Cardiometabolic Differences in Children Born After in Vitro Fertilization: Follow-Up Study
J. Clin. Endocrinol. Metab., May 1, 2008; 93(5): 1682 - 1688.
[Abstract] [Full Text] [PDF]

C. E. Minge, B. D. Bennett, R. J. Norman, and R. L. Robker
Peroxisome Proliferator-Activated Receptor-{gamma} Agonist Rosiglitazone Reverses the Adverse Effects of Diet-Induced Obesity on Oocyte Quality
Endocrinology, May 1, 2008; 149(5): 2646 - 2656.
[Abstract] [Full Text] [PDF]

A. J. Watkins, A. Wilkins, C. Cunningham, V. H. Perry, M. J. Seet, C. Osmond, J. J. Eckert, C. Torrens, F. R. A. Cagampang, J. Cleal, et al.
Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring
J. Physiol., April 15, 2008; 586(8): 2231 - 2244.
[Abstract] [Full Text] [PDF]

E. Kajantie, D. J P Barker, C. Osmond, T. Forsen, and J. G Eriksson
Growth before 2 years of age and serum lipids 60 years later: The Helsinki Birth Cohort Study
Int. J. Epidemiol., April 1, 2008; 37(2): 280 - 289.
[Abstract] [Full Text] [PDF]

A. J Watkins, E. Ursell, R. Panton, T. Papenbrock, L. Hollis, C. Cunningham, A. Wilkins, V. H. Perry, B. Sheth, W. Y. Kwong, et al.
Adaptive Responses by Mouse Early Embryos to Maternal Diet Protect Fetal Growth but Predispose to Adult Onset Disease
Biol Reprod, February 1, 2008; 78(2): 299 - 306.
[Abstract] [Full Text] [PDF]

B Mahsoudi, A Li, and C O'Neill
Assessment of the Long-Term and Transgenerational Consequences of Perturbing Preimplantation Embryo Development in Mice
Biol Reprod, November 1, 2007; 77(5): 889 - 896.
[Abstract] [Full Text] [PDF]

Wenjing Zhong, Yufen Xie, Yingchun Wang, J. Lewis, A. Trostinskaia, Fangfei Wang, E. E. Puscheck, and D. A. Rappolee
Use of Hyperosmolar Stress to Measure Stress-Activated Protein Kinase Activation and Function in Human HTR Cells and Mouse Trophoblast Stem Cells
Reproductive Sciences, September 1, 2007; 14(6): 534 - 547.
[Abstract] [PDF]

Y. Xie, W. Zhong, Y. Wang, A. Trostinskaia, F. Wang, E.E. Puscheck, and D.A. Rappolee
Using hyperosmolar stress to measure biologic and stress-activated protein kinase responses in preimplantation embryos
Mol. Hum. Reprod., July 1, 2007; 13(7): 473 - 481.
[Abstract] [Full Text] [PDF]

J. P. Porter, S. H. King, and A. D. Honeycutt
Prenatal high-salt diet in the Sprague-Dawley rat programs blood pressure and heart rate hyperresponsiveness to stress in adult female offspring
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2007; 293(1): R334 - R342.
[Abstract] [Full Text] [PDF]

J. G. Eriksson, T. J. Forsen, E. Kajantie, C. Osmond, and D. J.P. Barker
Childhood Growth and Hypertension in Later Life
Hypertension, June 1, 2007; 49(6): 1415 - 1421.
[Abstract] [Full Text] [PDF]

J. K. Cleal, K. R. Poore, J. P. Boullin, O. Khan, R. Chau, O. Hambidge, C. Torrens, J. P. Newman, L. Poston, D. E. Noakes, et al.
Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood
PNAS, May 29, 2007; 104(22): 9529 - 9533.
[Abstract] [Full Text] [PDF]

A. J. Watkins, D. Platt, T. Papenbrock, A. Wilkins, J. J. Eckert, W. Y. Kwong, C. Osmond, M. Hanson, and T. P. Fleming
From the Cover: Mouse embryo culture induces changes in postnatal phenotype including raised systolic blood pressure
PNAS, March 27, 2007; 104(13): 5449 - 5454.
[Abstract] [Full Text] [PDF]

P D Gluckman and M A Hanson
Adult disease: echoes of the past
Eur. J. Endocrinol., November 1, 2006; 155(suppl_1): S47 - S50.
[Abstract] [Full Text] [PDF]

A. Chamson-Reig, S. M Thyssen, E. Arany, and D. J Hill
Altered pancreatic morphology in the offspring of pregnant rats given reduced dietary protein is time and gender specific.
J. Endocrinol., October 1, 2006; 191(1): 83 - 92.
[Abstract] [Full Text] [PDF]

C. Thone-Reineke, P. Kalk, M. Dorn, S. Klaus, K. Simon, T. Pfab, M. Godes, P. Persson, T. Unger, and B. Hocher
High-protein nutrition during pregnancy and lactation programs blood pressure, food efficiency, and body weight of the offspring in a sex-dependent manner
Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2006; 291(4): R1025 - R1030.
[Abstract] [Full Text] [PDF]

A.-M. Samuelsson, C. Alexanderson, J. Molne, B. Haraldsson, P. Hansell, and A. Holmang
Prenatal exposure to interleukin-6 results in hypertension and alterations in the renin-angiotensin system of the rat
J. Physiol., September 15, 2006; 575(3): 855 - 867.
[Abstract] [Full Text] [PDF]

B. Dzyuba, K. J. W. Van Look, A. Cliffe, H. J. Koldewey, and W. V. Holt
Effect of parental age and associated size on fecundity, growth and survival in the yellow seahorse Hippocampus kuda
J. Exp. Biol., August 15, 2006; 209(16): 3055 - 3061.
[Abstract] [Full Text] [PDF]

W. Y. Kwong, D. J Miller, E. Ursell, A. E Wild, A. P Wilkins, C. Osmond, F. W Anthony, and T. P Fleming
Imprinted gene expression in the rat embryo-fetal axis is altered in response to periconceptional maternal low protein diet.
Reproduction, August 1, 2006; 132(2): 265 - 277.
[Abstract] [Full Text] [PDF]

M. Auroux
The child of problems.
Hum. Reprod., July 1, 2006; 21(7): 1943 - 1944.
[Full Text] [PDF]

F H Bloomfield, M H Oliver, and J E Harding
The late effects of fetal growth patterns.
Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2006; 91(4): F299 - F304.
[Abstract] [Full Text] [PDF]

W. D. Rees, F. A. Wilson, and C. A. Maloney
Sulfur Amino Acid Metabolism in Pregnancy: The Impact of Methionine in the Maternal Diet
J. Nutr., June 1, 2006; 136(6): 1701S - 1705S.
[Abstract] [Full Text] [PDF]

H. S. Andersen, L. Gambling, G. Holtrop, and H. J. McArdle
Maternal Iron Deficiency Identifies Critical Windows for Growth and Cardiovascular Development in the Rat Postimplantation Embryo
J. Nutr., May 1, 2006; 136(5): 1171 - 1177.
[Abstract] [Full Text] [PDF]

G. A. Thouas, A. O. Trounson, and G. M. Jones
Developmental Effects of Sublethal Mitochondrial Injury in Mouse Oocytes
Biol Reprod, May 1, 2006; 74(5): 969 - 977.
[Abstract] [Full Text] [PDF]

C. Torrens, L. Brawley, F. W. Anthony, C. S. Dance, R. Dunn, A. A. Jackson, L. Poston, and M. A. Hanson
Folate Supplementation During Pregnancy Improves Offspring Cardiovascular Dysfunction Induced by Protein Restriction
Hypertension, May 1, 2006; 47(5): 982 - 987.
[Abstract] [Full Text] [PDF]

Y. Xie, E.E. Puscheck, and D.A. Rappolee
Effects of SAPK/JNK inhibitors on preimplantation mouse embryo development are influenced greatly by the amount of stress induced by the media
Mol. Hum. Reprod., April 1, 2006; 12(4): 217 - 224.
[Abstract] [Full Text] [PDF]

L. J. Van Winkle, J. K. Tesch, A. Shah, and A. L. Campione
System B0,+ amino acid transport regulates the penetration stage of blastocyst implantation with possible long-term developmental consequences through adulthood
Hum. Reprod. Update, March 1, 2006; 12(2): 145 - 157.
[Abstract] [Full Text] [PDF]

A. Watkins, A. Wilkins, C. Osmond, C. M. Warner, M. Comiskey, M. Hanson, and T. P. Fleming
The influence of mouse Ped gene expression on postnatal development
J. Physiol., February 15, 2006; 571(1): 211 - 220.
[Abstract] [Full Text] [PDF]

B. T. Alexander
Fetal programming of hypertension
Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2006; 290(1): R1 - R10.
[Abstract] [Full Text] [PDF]

R. M Schultz
From egg to embryo: a peripatetic journey
Reproduction, December 1, 2005; 130(6): 825 - 828.
[Abstract] [Full Text] [PDF]

A. A. Jackson
Integrating the Ideas of Life Course across Cellular, Individual, and Population Levels in Cancer Causation
J. Nutr., December 1, 2005; 135(12): 2927S - 2933S.
[Abstract] [Full Text] [PDF]

C. A Maloney and W. D Rees
Gene-nutrient interactions during fetal development
Reproduction, October 1, 2005; 130(4): 401 - 410.
[Abstract] [Full Text] [PDF]

V. M. Vehaskari and L. L. Woods
Prenatal Programming of Hypertension: Lessons from Experimental Models
J. Am. Soc. Nephrol., September 1, 2005; 16(9): 2545 - 2556.
[Full Text] [PDF]

D. J.P. Barker and S. P. Bagby
Developmental Antecedents of Cardiovascular Disease: A Historical Perspective
J. Am. Soc. Nephrol., September 1, 2005; 16(9): 2537 - 2544.
[Abstract] [Full Text] [PDF]

D. G. Hemmings, S. J. Williams, and S. T. Davidge
Increased myogenic tone in 7-month-old adult male but not female offspring from rat dams exposed to hypoxia during pregnancy
Am J Physiol Heart Circ Physiol, August 1, 2005; 289(2): H674 - H682.
[Abstract] [Full Text] [PDF]

K. A. Lillycrop, E. S. Phillips, A. A. Jackson, M. A. Hanson, and G. C. Burdge
Dietary Protein Restriction of Pregnant Rats Induces and Folic Acid Supplementation Prevents Epigenetic Modification of Hepatic Gene Expression in the Offspring
J. Nutr., June 1, 2005; 135(6): 1382 - 1386.
[Abstract] [Full Text] [PDF]

M. A. Hanson and P. D. Gluckman
Developmental processes and the induction of cardiovascular function: conceptual aspects
J. Physiol., May 15, 2005; 565(1): 27 - 34.
[Abstract] [Full Text] [PDF]

S. M. MacLaughlin, S. K. Walker, C. T. Roberts, D. O. Kleemann, and I. C. McMillen
Periconceptional nutrition and the relationship between maternal body weight changes in the periconceptional period and feto-placental growth in the sheep
J. Physiol., May 15, 2005; 565(1): 111 - 124.
[Abstract] [Full Text] [PDF]

R. M. Roberts
Embryo Culture Conditions: What Embryos Like Best
Endocrinology, May 1, 2005; 146(5): 2140 - 2141.
[Full Text] [PDF]

C. Sjoblom, C. T. Roberts, M. Wikland, and S. A. Robertson
Granulocyte-Macrophage Colony-Stimulating Factor Alleviates Adverse Consequences of Embryo Culture on Fetal Growth Trajectory and Placental Morphogenesis
Endocrinology, May 1, 2005; 146(5): 2142 - 2153.
[Abstract] [Full Text] [PDF]

E. Assemat, S. Vinot, F. Gofflot, P. Linsel-Nitschke, F. Illien, F. Chatelet, P. Verroust, S. Louvet-Vallee, F. Rinninger, and R. Kozyraki
Expression and Role of Cubilin in the Internalization of Nutrients During the Peri-Implantation Development of the Rodent Embryo
Biol Reprod, May 1, 2005; 72(5): 1079 - 1086.
[Abstract] [Full Text] [PDF]

P. D Gluckman, M. A Hanson, H. G Spencer, and P. Bateson
Environmental influences during development and their later consequences for health and disease: implications for the interpretation of empirical studies
Proc R Soc B, April 7, 2005; 272(1564): 671 - 677.
[Abstract] [Full Text] [PDF]

S. Y Huh, S. L Rifas-Shiman, K. P Kleinman, J. W Rich-Edwards, S. E Lipshultz, and M. W Gillman
Maternal protein intake is not associated with infant blood pressure
Int. J. Epidemiol., April 1, 2005; 34(2): 378 - 384.
[Abstract] [Full Text] [PDF]

J. Schwartz and J. L. Morrison
Impact and mechanisms of fetal physiological programming
Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2005; 288(1): R11 - R15.
[Full Text] [PDF]

L. J. Edwards, J. R. McFarlane, K. G. Kauter, and I. C. McMillen
Impact of periconceptional nutrition on maternal and fetal leptin and fetal adiposity in singleton and twin pregnancies
Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2005; 288(1): R39 - R45.
[Abstract] [Full Text] [PDF]

I. Y. Khan, V. Dekou, G. Douglas, R. Jensen, M. A. Hanson, L. Poston, and P. D. Taylor
A high-fat diet during rat pregnancy or suckling induces cardiovascular dysfunction in adult offspring
Am J Physiol Regulatory Integrative Comp Physiol, January 1, 2005; 288(1): R127 - R133.
[Abstract] [Full Text] [PDF]

S. Davies, M.C. Richardson, F.W. Anthony, D. Mukhtar, and I.T. Cameron
Progesterone inhibits insulin-like growth factor binding protein-1 (IGFBP-1) production by explants of the Fallopian tube
Mol. Hum. Reprod., December 1, 2004; 10(12): 935 - 939.
[Abstract] [Full Text] [PDF]

D.J.P. Barker
The Developmental Origins of Adult Disease
J. Am. Coll. Nutr., December 1, 2004; 23(suppl_6): 588S - 595S.
[Abstract] [Full Text] [PDF]

Y.-G. Gangloff, M. Mueller, S. G. Dann, P. Svoboda, M. Sticker, J.-F. Spetz, S. H. Um, E. J. Brown, S. Cereghini, G. Thomas, et al.
Disruption of the Mouse mTOR Gene Leads to Early Postimplantation Lethality and Prohibits Embryonic Stem Cell Development
Mol. Cell. Biol., November 1, 2004; 24(21): 9508 - 9516.
[Abstract] [Full Text] [PDF]

T. P. Fleming, W. Y. Kwong, R. Porter, E. Ursell, I. Fesenko, A. Wilkins, D. J. Miller, A. J. Watkins, and J. J. Eckert
The Embryo and Its Future
Biol Reprod, October 1, 2004; 71(4): 1046 - 1054.
[Abstract] [Full Text] [PDF]

P. D. Gluckman and M. A. Hanson
Living with the Past: Evolution, Development, and Patterns of Disease
Science, September 17, 2004; 305(5691): 1733 - 1736.
[Abstract] [Full Text] [PDF]

D. S. Gardner, S. Pearce, J. Dandrea, R. Walker, M. M. Ramsay, T. Stephenson, and M. E. Symonds
Peri-Implantation Undernutrition Programs Blunted Angiotensin II Evoked Baroreflex Responses in Young Adult Sheep
Hypertension, June 1, 2004; 43(6): 1290 - 1296.
[Abstract] [Full Text] [PDF]

D. J. Ecker, P. Stein, Z. Xu, C. J. Williams, G. S. Kopf, W. B. Bilker, T. Abel, and R. M. Schultz
Long-term effects of culture of preimplantation mouse embryos on behavior
PNAS, February 10, 2004; 101(6): 1595 - 1600.
[Abstract] [Full Text] [PDF]

T Forsen, C Osmond, J G Eriksson, and D J P Barker
Growth of girls who later develop coronary heart disease
Heart, January 1, 2004; 90(1): 20 - 24.
[Abstract] [Full Text] [PDF]

N. M Orsi and H. J Leese
Ammonium exposure and pyruvate affect the amino acid metabolism of bovine blastocysts in vitro
Reproduction, January 1, 2004; 127(1): 131 - 140.
[Abstract] [Full Text] [PDF]

T J. McDonald, K. L. Franko, J. M. Brown, S. L. Jenkins, P. W. Nathanielsz, and M. J. Nijland
Betamethasone in the Last Week of Pregnancy Causes Fetal Growth Rtardation but Not Adult Hypertension in Rats
Reproductive Sciences, December 1, 2003; 10(8): 469 - 473.
[Abstract] [PDF]

H. Nishina, L. R Green, H. H G McGarrigle, D. E Noakes, L. Poston, and M. A Hanson
Effect of nutritional restriction in early pregnancy on isolated femoral artery function in mid-gestation fetal sheep
J. Physiol., December 1, 2003; 553(2): 637 - 647.
[Abstract] [Full Text] [PDF]

M. d. C. P. Franco, D. Nigro, Z. B Fortes, R. C.A Tostes, M. H. C Carvalho, S. R. R. Lucas, G. N. Gomes, T. M. Coimbra, and F. Z. Gil
Intrauterine undernutrition--renal and vascular origin of hypertension
Cardiovasc Res, November 1, 2003; 60(2): 228 - 234.
[Abstract] [Full Text] [PDF]

D. Barker
Commentary: Developmental origins of raised serum cholesterol
Int. J. Epidemiol., October 1, 2003; 32(5): 876 - 877.
[Full Text] [PDF]

C. S. Rosenfeld, K. M. Grimm, K. A. Livingston, A. M. Brokman, W. E. Lamberson, and R. M. Roberts
Striking variation in the sex ratio of pups born to mice according to whether maternal diet is high in fat or carbohydrate
PNAS, April 15, 2003; 100(8): 4628 - 4632.
[Abstract] [Full Text] [PDF]

C. Torrens, L. Brawley, A. C Barker, S. Itoh, L. Poston, and M. A Hanson
Maternal protein restriction in the rat impairs resistance artery but not conduit artery function in pregnant offspring
J. Physiol., February 15, 2003; 547(1): 77 - 84.
[Abstract] [Full Text] [PDF]

D. Barker, J. Eriksson, T Forsen, and C Osmond
Fetal origins of adult disease: strength of effects and biological basis
Int. J. Epidemiol., December 1, 2002; 31(6): 1235 - 1239.
[Abstract] [Full Text] [PDF]

K. M. Moritz, K. Johnson, R. Douglas-Denton, E. M. Wintour, and M. Dodic
Maternal Glucocorticoid Treatment Programs Alterations in the Renin-Angiotensin System of the Ovine Fetal Kidney
Endocrinology, November 1, 2002; 143(11): 4455 - 4463.
[Abstract] [Full Text] [PDF]

J. G. Thompson, K. L. Kind, C. T. Roberts, S. A. Robertson, and J. S. Robinson
Epigenetic risks related to assisted reproductive technologies: Short- and long-term consequences for the health of children conceived through assisted reproduction technology: more reason for caution?
Hum. Reprod., November 1, 2002; 17(11): 2783 - 2786.
[Abstract] [Full Text] [PDF]

M. Dodic, T. Abouantoun, A. O'Connor, E. M. Wintour, and K. M. Moritz
Programming Effects of Short Prenatal Exposure to Dexamethasone in Sheep
Hypertension, November 1, 2002; 40(5): 729 - 734.
[Abstract] [Full Text] [PDF]

M. d. C. P Franco, R. M. M.P Arruda, A. P. V. Dantas, E. M. Kawamoto, Z. B Fortes, C. Scavone, M. H. C Carvalho, R. C.A Tostes, and D. Nigro
Intrauterine undernutrition: expression and activity of the endothelial nitric oxide synthase in male and female adult offspring
Cardiovasc Res, October 1, 2002; 56(1): 145 - 153.
[Abstract] [Full Text] [PDF]

C. J. Bean, T. J. Hassold, L. Judis, and P. A. Hunt
Fertilization in vitro increases non-disjunction during early cleavage divisions in a mouse model system
Hum. Reprod., September 1, 2002; 17(9): 2362 - 2367.
[Abstract] [Full Text] [PDF]

L. J. Edwards and I. C. McMillen
Periconceptional nutrition programs development of the cardiovascular system in the fetal sheep
Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2002; 283(3): R669 - R679.
[Abstract] [Full Text] [PDF]

N. Fontanier-Razzaq, D. N. Harries, S. M. Hay, and W. D. Rees
Amino Acid Deficiency Up-regulates Specific mRNAs in Murine Embryonic Cells
J. Nutr., August 1, 2002; 132(8): 2137 - 2142.
[Abstract] [Full Text] [PDF]

M. DODIC, V. HANTZIS, J. DUNCAN, S. REES, I. KOUKOULAS, K. JOHNSON, E. M. WINTOUR, and K. MORITZ
Programming effects of short prenatal exposure to cortisol
FASEB J, July 1, 2002; 16(9): 1017 - 1026.
[Abstract] [Full Text] [PDF]

L.J. Edwards and I.C. McMillen
Impact of Maternal Undernutrition During the Periconceptional Period, Fetal Number, and Fetal Sex on the Development of the Hypothalamo-Pituitary Adrenal Axis in Sheep During Late Gestation
Biol Reprod, May 1, 2002; 66(5): 1562 - 1569.
[Abstract] [Full Text]

Y. G. Chung, M. R.W. Mann, M. S. Bartolomei, and K. E. Latham
Nuclear-Cytoplasmic "Tug of War" During Cloning: Effects of Somatic Cell Nuclei on Culture Medium Preferences of Preimplantation Cloned Mouse Embryos
Biol Reprod, April 1, 2002; 66(4): 1178 - 1184.
[Abstract] [Full Text] [PDF]

K. Yoshioka, C. Suzuki, A. Tanaka, I. M.-K. Anas, and S. Iwamura
Birth of Piglets Derived from Porcine Zygotes Cultured in a Chemically Defined Medium
Biol Reprod, January 1, 2002; 66(1): 112 - 119.
[Abstract] [Full Text]

D. J P Barker
The malnourished baby and infant: Relationship with Type 2 diabetes
Br. Med. Bull., November 1, 2001; 60(1): 69 - 88.
[Abstract] [Full Text] [PDF]

C. E Bertram and M. A Hanson
Animal models and programming of the metabolic syndrome: Type 2 diabetes
Br. Med. Bull., November 1, 2001; 60(1): 103 - 121.
[Abstract] [Full Text] [PDF]

C. C. Metges
Does Dietary Protein in Early Life Affect the Development of Adiposity in Mammals?
J. Nutr., July 1, 2001; 131(7): 2062 - 2066.
[Abstract] [Full Text] [PDF]

P. D. Gluckman
Editorial: Nutrition, Glucocorticoids, Birth Size, and Adult Disease
Endocrinology, May 1, 2001; 142(5): 1689 - 1691.
[Full Text]

M. Dodic, C. Samuel, K. Moritz, E. M. Wintour, J. Morgan, L. Grigg, and J. Wong
Impaired Cardiac Functional Reserve and Left Ventricular Hypertrophy in Adult Sheep After Prenatal Dexamethasone Exposure
Circ. Res., September 28, 2001; 89(7): 623 - 629.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Kwong, W. Y.

Articles by Fleming, T. P.

Search for Related Content

PubMed

PubMed Citation

Articles by Kwong, W. Y.

Articles by Fleming, T. P.

Social Bookmarking

What's this?

				S. R. Milligan, W. V. Holt, and R. Lloyd Impacts of climate change and environmental factors on reproduction and development in wildlife Phil Trans R Soc B, November 27, 2009; 364(1534): 3313 - 3319. [Abstract] [Full Text] [PDF]

				C. Torrens, T. H. Snelling, R. Chau, M. Shanmuganathan, J. K. Cleal, K. R. Poore, D. E. Noakes, L. Poston, M. A. Hanson, and L. R. Green Effects of pre- and periconceptional undernutrition on arterial function in adult female sheep are vascular bed dependent Exp Physiol, September 1, 2009; 94(9): 1024 - 1033. [Abstract] [Full Text] [PDF]

				E. S. Lucas, S. L. Finn, A. Cox, F. R. Lock, and A. J. Watkins The impact of maternal high fat nutrition on the next generation: food for thought? J. Physiol., July 15, 2009; 587(14): 3425 - 3426. [Full Text] [PDF]

				I. Cetin, C. Berti, and S. Calabrese Role of micronutrients in the periconceptional period Hum. Reprod. Update, June 30, 2009; (2009) dmp025v1. [Abstract] [Full Text] [PDF]

				C. E. Bell, N. M.K. Lariviere, P. H. Watson, and A. J. Watson Mitogen-activated protein kinase (MAPK) pathways mediate embryonic responses to culture medium osmolarity by regulating Aquaporin 3 and 9 expression and localization, as well as embryonic apoptosis Hum. Reprod., June 1, 2009; 24(6): 1373 - 1386. [Abstract] [Full Text] [PDF]

				Z. Wang, Z. Huang, G. Lu, L. Lin, and M. Ferrari Hypoxia during pregnancy in rats leads to early morphological changes of atherosclerosis in adult offspring Am J Physiol Heart Circ Physiol, May 1, 2009; 296(5): H1321 - H1328. [Abstract] [Full Text] [PDF]

				J.J. Eppig, M.J. O'Brien, K. Wigglesworth, A. Nicholson, W. Zhang, and B.A. King Effect of in vitro maturation of mouse oocytes on the health and lifespan of adult offspring Hum. Reprod., April 1, 2009; 24(4): 922 - 928. [Abstract] [Full Text] [PDF]

				M. Mitchell, S. L. Schulz, D. T. Armstrong, and M. Lane Metabolic and Mitochondrial Dysfunction in Early Mouse Embryos Following Maternal Dietary Protein Intervention Biol Reprod, April 1, 2009; 80(4): 622 - 630. [Abstract] [Full Text] [PDF]

				D. M. Burrage, L. Braddick, J. K. Cleal, P. Costello, D. E. Noakes, M. A. Hanson, and L. R. Green The late gestation fetal cardiovascular response to hypoglycaemia is modified by prior peri-implantation undernutrition in sheep J. Physiol., February 1, 2009; 587(3): 611 - 624. [Abstract] [Full Text] [PDF]

				M. Ceelen, M. M. van Weissenbruch, J. P.W. Vermeiden, F. E. van Leeuwen, and H. A. Delemarre-van de Waal Pubertal development in children and adolescents born after IVF and spontaneous conception Hum. Reprod., December 1, 2008; 23(12): 2791 - 2798. [Abstract] [Full Text] [PDF]

				J. S. Gilbert and M. J. Nijland Sex differences in the developmental origins of hypertension and cardiorenal disease Am J Physiol Regulatory Integrative Comp Physiol, December 1, 2008; 295(6): R1941 - R1952. [Abstract] [Full Text] [PDF]

				H. D. Morgan, X. L. Jin, A. Li, E. Whitelaw, and C. O'Neill The Culture of Zygotes to the Blastocyst Stage Changes the Postnatal Expression of an Epigentically Labile Allele, Agouti Viable Yellow, in Mice Biol Reprod, October 1, 2008; 79(4): 618 - 623. [Abstract] [Full Text] [PDF]

				P. D. Gluckman, M. A. Hanson, C. Cooper, and K. L. Thornburg Effect of In Utero and Early-Life Conditions on Adult Health and Disease N. Engl. J. Med., July 3, 2008; 359(1): 61 - 73. [Full Text] [PDF]

				C. E. Minge, B. D. Bennett, R. J. Norman, and R. L. Robker Peroxisome Proliferator-Activated Receptor-{gamma} Agonist Rosiglitazone Reverses the Adverse Effects of Diet-Induced Obesity on Oocyte Quality Endocrinology, May 1, 2008; 149(5): 2646 - 2656. [Abstract] [Full Text] [PDF]

				A. J. Watkins, A. Wilkins, C. Cunningham, V. H. Perry, M. J. Seet, C. Osmond, J. J. Eckert, C. Torrens, F. R. A. Cagampang, J. Cleal, et al. Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring J. Physiol., April 15, 2008; 586(8): 2231 - 2244. [Abstract] [Full Text] [PDF]

				E. Kajantie, D. J P Barker, C. Osmond, T. Forsen, and J. G Eriksson Growth before 2 years of age and serum lipids 60 years later: The Helsinki Birth Cohort Study Int. J. Epidemiol., April 1, 2008; 37(2): 280 - 289. [Abstract] [Full Text] [PDF]

				A. J Watkins, E. Ursell, R. Panton, T. Papenbrock, L. Hollis, C. Cunningham, A. Wilkins, V. H. Perry, B. Sheth, W. Y. Kwong, et al. Adaptive Responses by Mouse Early Embryos to Maternal Diet Protect Fetal Growth but Predispose to Adult Onset Disease Biol Reprod, February 1, 2008; 78(2): 299 - 306. [Abstract] [Full Text] [PDF]

				B Mahsoudi, A Li, and C O'Neill Assessment of the Long-Term and Transgenerational Consequences of Perturbing Preimplantation Embryo Development in Mice Biol Reprod, November 1, 2007; 77(5): 889 - 896. [Abstract] [Full Text] [PDF]

				Wenjing Zhong, Yufen Xie, Yingchun Wang, J. Lewis, A. Trostinskaia, Fangfei Wang, E. E. Puscheck, and D. A. Rappolee Use of Hyperosmolar Stress to Measure Stress-Activated Protein Kinase Activation and Function in Human HTR Cells and Mouse Trophoblast Stem Cells Reproductive Sciences, September 1, 2007; 14(6): 534 - 547. [Abstract] [PDF]

				Y. Xie, W. Zhong, Y. Wang, A. Trostinskaia, F. Wang, E.E. Puscheck, and D.A. Rappolee Using hyperosmolar stress to measure biologic and stress-activated protein kinase responses in preimplantation embryos Mol. Hum. Reprod., July 1, 2007; 13(7): 473 - 481. [Abstract] [Full Text] [PDF]

				J. P. Porter, S. H. King, and A. D. Honeycutt Prenatal high-salt diet in the Sprague-Dawley rat programs blood pressure and heart rate hyperresponsiveness to stress in adult female offspring Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2007; 293(1): R334 - R342. [Abstract] [Full Text] [PDF]

				J. G. Eriksson, T. J. Forsen, E. Kajantie, C. Osmond, and D. J.P. Barker Childhood Growth and Hypertension in Later Life Hypertension, June 1, 2007; 49(6): 1415 - 1421. [Abstract] [Full Text] [PDF]

				J. K. Cleal, K. R. Poore, J. P. Boullin, O. Khan, R. Chau, O. Hambidge, C. Torrens, J. P. Newman, L. Poston, D. E. Noakes, et al. Mismatched pre- and postnatal nutrition leads to cardiovascular dysfunction and altered renal function in adulthood PNAS, May 29, 2007; 104(22): 9529 - 9533. [Abstract] [Full Text] [PDF]

				A. J. Watkins, D. Platt, T. Papenbrock, A. Wilkins, J. J. Eckert, W. Y. Kwong, C. Osmond, M. Hanson, and T. P. Fleming From the Cover: Mouse embryo culture induces changes in postnatal phenotype including raised systolic blood pressure PNAS, March 27, 2007; 104(13): 5449 - 5454. [Abstract] [Full Text] [PDF]

				P D Gluckman and M A Hanson Adult disease: echoes of the past Eur. J. Endocrinol., November 1, 2006; 155(suppl_1): S47 - S50. [Abstract] [Full Text] [PDF]

				A. Chamson-Reig, S. M Thyssen, E. Arany, and D. J Hill Altered pancreatic morphology in the offspring of pregnant rats given reduced dietary protein is time and gender specific. J. Endocrinol., October 1, 2006; 191(1): 83 - 92. [Abstract] [Full Text] [PDF]

				C. Thone-Reineke, P. Kalk, M. Dorn, S. Klaus, K. Simon, T. Pfab, M. Godes, P. Persson, T. Unger, and B. Hocher High-protein nutrition during pregnancy and lactation programs blood pressure, food efficiency, and body weight of the offspring in a sex-dependent manner Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2006; 291(4): R1025 - R1030. [Abstract] [Full Text] [PDF]

				A.-M. Samuelsson, C. Alexanderson, J. Molne, B. Haraldsson, P. Hansell, and A. Holmang Prenatal exposure to interleukin-6 results in hypertension and alterations in the renin-angiotensin system of the rat J. Physiol., September 15, 2006; 575(3): 855 - 867. [Abstract] [Full Text] [PDF]

				B. Dzyuba, K. J. W. Van Look, A. Cliffe, H. J. Koldewey, and W. V. Holt Effect of parental age and associated size on fecundity, growth and survival in the yellow seahorse Hippocampus kuda J. Exp. Biol., August 15, 2006; 209(16): 3055 - 3061. [Abstract] [Full Text] [PDF]

				W. Y. Kwong, D. J Miller, E. Ursell, A. E Wild, A. P Wilkins, C. Osmond, F. W Anthony, and T. P Fleming Imprinted gene expression in the rat embryo-fetal axis is altered in response to periconceptional maternal low protein diet. Reproduction, August 1, 2006; 132(2): 265 - 277. [Abstract] [Full Text] [PDF]