Suppression of the rbf null mutants by a de2f1 allele that lacks transactivation domain

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Asano, M., Nevins, J. R. and Wharton, R. P (1996). Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. Genes Dev 10, 1422-1432.[Abstract/Free Full Text]

Bartek, J., Bartkova, J. and Lukas, J (1997). The retinoblastoma protein pathway in cell cycle control and cancer. Exp. Cell Res 237, 1-6.[Medline]

Beijersbergen, R. L., Kerkhoven, R. M., Zhu, L., Carlee, L., Voorhoeve, P. M. and Bernards, R (1994). E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev 8, 2680-2690.[Abstract/Free Full Text]

Brook, A., Xie, J.-E., Du, W. and Dyson, N (1996). Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells. EMBO J 15, 3676-3683.[Medline]

Chen, P.-L., Riley, D. J., Chen, Y. and Lee, W.-H (1996). Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. Genes Dev 10, 2794-2804.[Abstract/Free Full Text]

Clarke, A., Maandag, E., van Roon, M., van der Lugt, N., van der Valk, M., Hooper, M., Berns, A. and te Riele, H (1992). Requirement for a functional Rb-1 gene in murine development. Nature 359, 328-330.[Medline]

Cobrinik, D., Lee, M.-H., Hannon, G., Mulligan, G., Bronson, R. T., Dyson, N., Harlow, E., Beach, D., Weinberg, R. A. and Jacks, T (1996). Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev 10, 1633-1644.[Abstract/Free Full Text]

Dalton, S (1992). Cell cycle regulation of the human cdc2 gene. EMBO J 11, 1797-1804.[Medline]

Du, W. and Dyson, N (1999). The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis. EMBO J 18, 916-925.[Medline]

Du, W., Vidal, M., Xie, J.-E. and Dyson, N (1996). RBF , a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev 10, 1206-1218.[Abstract/Free Full Text]

Du, W., Xie, J.-E. and Dyson, N (1996). Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye. EMBO J 15, 3684-3692.[Medline]

Duronio, R. J., Bonnette, P. C. and O'Farrell, P. H (1998). Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition [published erratum appears in Mol Cell Biol 1998 May;18(5):3101]. Mol. Cell Biol 18, 141-151.[Abstract/Free Full Text]

Duronio, R. J., Brook, A., Dyson, N. and O'Farrell, P. H (1996). E2F-induced S phase requires cyclin E. Genes Dev 10, 2505-2513.[Abstract/Free Full Text]

Duronio, R. J. and O'Farrell, P. H (1994). Developmental control of a G1-S transcriptional program in Drosophila. Development 120, 1503-1515.[Abstract]

Duronio, R. J. and O'Farrell, P. H (1995). Developmental control of the G1to S transition in Drosophila; cyclin E is a limiting downstream target of E2F. Genes Dev 9, 1456-1468.[Abstract/Free Full Text]

Duronio, R. J., O'Farrell, P. H., Xie, J.-E., Brook, A. and Dyson, N (1995). The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev 9, 1445-1455.[Abstract/Free Full Text]

Dynlacht, B. D., Brook, A., Dembski, M. S., Yenush, L. and Dyson, N (1994). DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Proc. Natl. Acad. Sci. USA 91, 6359-6363.[Abstract/Free Full Text]

Dyson, N (1998). The regulation of E2F by pRB-family proteins. Genes Dev 12, 2245-2262.[Free Full Text]

Fearon, E. R (1997). Human cancer syndromes: clues to the origin and nature of cancer. Science 278, 1043-1050.[Abstract/Free Full Text]

Field, S. J., Tsai, F.-Y., Kuo, F., Zubiaga, A. M., Kaelin, J., W.G., Livingston, D. M., Orkin, S. H. and Greenberg, M. E (1996). E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 85, 549-561.[Medline]

Geng, Y., Eaton, E. N., Picon, M., Roberts, J. M., Lundberg, A. S., Gifford, A., Sardet, C. and Weinberg, R. A (1996). Regulation of cyclin E transcription by E2Fs and retinoblastoma protein. Oncogene 12, 1173-1180.[Medline]

Ginsberg, D., Vairo, G., Chittenden, T., Xiao, Z. X., Xu, G., Wydner, K. L., DeCaprio, J. A., Lawrence, J. B. and Livingston, D. M (1994). E2F-4, a new member of the E2F transcription factor family, interacts with p107. Genes Dev 8, 2665-2679.[Abstract/Free Full Text]

Girling, R., Partridge, J. F., Bandara, L. R., Burden, N., Totty, N. F., Hsuan, J. J. and La Thangue, N. B (1993). A new component of the transcription factor DRTF1/E2F. Nature 362, 83-87.[Medline]

Gu, W., Schneider, J. W., Condorelli, G., Kaushai, S., Mahdavi, V. and Nadal-Ginard, B (1993). Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72, 309-324.[Medline]

Helin, K., Lees, J. A., Vidal, M., Dyson, N., Harlow, E. and Fattaey, A (1992). A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell 70, 337-350.[Medline]

Horsfield, J., Penton, A., Secombe, J., Hoffman, F. M. and Richardson, H (1998). decapentaplegic is required for arrest in G1phase during Drosophila eye development. Development 125, 5069-5078.[Abstract]

Jacks, T., Fazeli, A., Schmitt, E. M., Bronson, R. T., Goodell, M. A. and Weinberg, R. A (1992). Effects of an Rb mutation in the mouse. Nature 359, 295-300.[Medline]

Johnson, D. G., Schwarz, J. K., Cress, W. D. and Nevins, J. R (1993). Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature 365, 349-352.[Medline]

Kaelin, W. G., Jr., Krek, W., Sellers, W. R., DeCaprio, J. A., Ajchenbaum, F., Fuchs, C. S., Chittenden, T., Li, Y., Farnham, P. J., Blanar, M. A., Livingston, D. M. and Flemington, E. K (1992). Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell 70, 351-364.[Medline]

Lam, E. W.-F. and Watson, R. J (1993). An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription. EMBO J 12, 2705-2713.[Medline]

Lavia, P. and Jansen-Durr, P (1999). E2F target genes and cell-cycle checkpoint control. BioEssays 21, 221-230.[Medline]

Lee, E. Y.-H. P., Chang, C.-Y., Hu, N., Wang, Y.-C. J., Lai, C.-C., Herrup, K., Lee, W.-H. and Bradley, A (1992). Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359, 288-294.[Medline]

Lee, M.-H., Williams, B. O., Mulligan, G., Mukai, S., Bronson, R. T., Dyson, N., Harlow, E. and Jacks, T (1996). Targeted disruption of p107: functional overlap between p107 and Rb. Genes Dev 10, 1621-1632.[Abstract/Free Full Text]

Lees, J. A., Saito, M., Vidal, M., Valentine, M., Look, T., Harlow, E., Dyson, N. and Helin, K (1993). The retinoblastoma protein binds to a family of E2F transcription factors. Mol. Cell. Biol 13, 7813-7825.[Abstract/Free Full Text]

Lukas, J., Petersen, B. O., Holm, K., Bartek, J. and Helin, K (1996). Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression. Mol. Cell. Biol 16, 1047-1057.[Abstract]

Mulligan, G. and Jacks, T (1998). The retinoblastoma gene family: cousins with overlapping interests. Trends Genet 14, 223-229.[Medline]

Nevins, J. R (1998). Toward an understanding of the functional complexity of the E2F and retinoblastoma families. Cell. Growth Differ 9, 585-593.[Medline]

Ohtani, K. and Nevins, J. R (1994). Functional properties of a Drosophila homolog of the E2F1 gene. Mol. Cell. Biol 14, 1603-1612.[Abstract/Free Full Text]

Ormondroyd, E., de la Luna, S. and La Thangue, N. B (1995). A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F. Oncogene 11, 1437-1446.[Medline]

Qin, X.-Q., Livingston, D. M., Ewen, M., Sellers, W. R., Arany, Z. and Kaelin, W. G (1995). The transcription factor E2F-1 is a downstream target of RB action. Mol. Cell. Biol 15, 742-755.[Abstract]

Riley, D. J., Lie, C. Y. and Lee, W. H (1997). Mutations of N-terminal regions render the retinoblastoma protein insufficient for functions in development and tumor suppression. Mol. Cell. Biol 17, 7342-7352.[Abstract]

Royzman, I., Austin, R. J., Bosco, G., Bell, S. P. and Orr-Weaver, T. L (1999). ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP. Genes Dev 13, 827-840.[Abstract/Free Full Text]

Royzman, I., Whittaker, A. J. and Orr-Weaver, T. L (1997). Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program. Genes Dev 11, 1999-2011.[Abstract/Free Full Text]

Sardet, C., Vidal, M., Cobrinik, D., Geng, Y., Onufryk, C., Chen, A. and Weinberg, R. A (1995). E2F-4 and E2F-5, two novel members of the E2F family, are expressed in the early phases of the cell cycle. Proc. Natl. Acad. Sci. USA 92, 2403-2407.[Abstract/Free Full Text]

Sawado, T., Yamaguchi, M., Nishimoto, Y., Ohno, K., Sakaguchi, K. and Matsukage, A (1998). dE2F2, a novel E2F-family transcription factor in Drosophila melanogaster. Biochem. Biophys. Res. Commun 251, 409-415.[Medline]

Sellers, W. R., Rodgers, J. W. and Kaelin, J., W. G (1995). A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. Proc. Natl. Acad. Sci. USA 92, 11544-11548.[Abstract/Free Full Text]

Seum, C., Spierer, A., Pauli, D., Szidonya, J., Reuter, G. and Spierer, P (1996). Position-effect variegation in Drosophila depends on dose of the gene encoding the E2F transcriptional activator and cell cycle regulator. Development 122, 1949-1956.[Abstract]

Shan, B. and Lee, W.-H (1994). Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell. Biol 14, 8166-8173.[Abstract/Free Full Text]

Shan, B., Zhu, X., Chen, P.-L., Durfee, T., Yang, Y., Sharp, D. and Lee, W.-H (1992). Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F. Mol. Cell. Biol 12, 5620-5631.[Abstract/Free Full Text]

Trimarchi, J. M., Fairchild, B., Verona, R., Moberg, K., Andon, N. and Lees, J. A (1998). E2F-6, a member of the E2F family that can behave as a transcriptional repressor. Proc. Natl. Acad. Sci. USA 95, 2850-2855.[Abstract/Free Full Text]

Tsai, K. Y., Hu, Y., Macleod, K. F., Crowley, D., Yamasaki, L. and Jacks, T (1998). Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos. Mol. Cell 2, 293-304.

Weinberg, R. A (1995). The retinoblastoma protein and cell cycle control. Cell 81, 323-330.[Medline]

Weintraub, S. J., Chow, K. N. B., Luo, R. X., Zhang, S. H., He, S. and Dean, D. C (1995). Mechanism of active transcriptional repression by the retinoblastoma protein. Nature 375, 812-815.[Medline]

Weintraub, S. J., Prater, C. A. and Dean, D. C (1992). Retinoblastoma protein switches the E2F site from positive to negative element. Nature 358, 259-261.[Medline]

Wu, C.-L., Zukerberg, L. R., Ngwu, C., Harlow, E. and Lees, J. A (1995). In vivo association of E2F and DP family proteins. Mol. Cell. Biol 15, 2536-2546.[Abstract]

Yamasaki, L., Jacks, T., Bronson, R., Goillot, E., Harlow, E. and Dyson, N (1996). Tumor induction and tissue atrophy in mice lacking E2F-1. Cell 85, 537-548.[Medline]

Zacksenhaus, E., Jiang, Z., Chung, D., Marth, J. D., Phillips, R. A. and Gallie, B. L (1996). pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis. Genes Dev 10, 3051-3064.[Abstract/Free Full Text]

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				A. M. Ambrus, V. I. Rasheva, B. N. Nicolay, and M. V. Frolov Mosaic Genetic Screen for Suppressors of the de2f1 Mutant Phenotype in Drosophila Genetics, September 1, 2009; 183(1): 79 - 92. [Abstract] [Full Text] [PDF]

				A. M. Ambrus, B. N. Nicolay, V. I. Rasheva, R. J. Suckling, and M. V. Frolov dE2F2-Independent Rescue of Proliferation in Cells Lacking an Activator dE2F1 Mol. Cell. Biol., December 15, 2007; 27(24): 8561 - 8570. [Abstract] [Full Text] [PDF]

				M. J. Sukhanova, D. K. Deb, G. M. Gordon, M. T. Matakatsu, and W. Du Proneural Basic Helix-Loop-Helix Proteins and Epidermal Growth Factor Receptor Signaling Coordinately Regulate Cell Type Specification and cdk Inhibitor Expression during Development Mol. Cell. Biol., April 15, 2007; 27(8): 2987 - 2996. [Abstract] [Full Text] [PDF]

				N.-S. Moon, L. Di Stefano, and N. Dyson A Gradient of Epidermal Growth Factor Receptor Signaling Determines the Sensitivity of rbf1 Mutant Cells to E2F-Dependent Apoptosis Mol. Cell. Biol., October 15, 2006; 26(20): 7601 - 7615. [Abstract] [Full Text] [PDF]

				M. V. Frolov, N.-S. Moon, and N. J. Dyson dDP Is Needed for Normal Cell Proliferation Mol. Cell. Biol., April 15, 2005; 25(8): 3027 - 3039. [Abstract] [Full Text] [PDF]

				D. K. Dimova, O. Stevaux, M. V. Frolov, and N. J. Dyson Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway Genes & Dev., September 15, 2003; 17(18): 2308 - 2320. [Abstract] [Full Text] [PDF]

				S. Szuplewski, B. Kottler, and R. Terracol The Drosophila bZIP transcription factor Vrille is involved in hair and cell growth Development, August 15, 2003; 130(16): 3651 - 3662. [Abstract] [Full Text] [PDF]

				D. S. Fay, E. Large, M. Han, and M. Darland lin-35/Rb and ubc-18, an E2 ubiquitin-conjugating enzyme, function redundantly to control pharyngeal morphogenesis in C. elegans Development, July 15, 2003; 130(14): 3319 - 3330. [Abstract] [Full Text] [PDF]

				S. Xin, L. Weng, J. Xu, and W. Du The role of RBF in developmentally regulated cell proliferation in the eye disc and in Cyclin D/Cdk4 induced cellular growth Development, March 5, 2003; 129(6): 1345 - 1356. [Abstract] [Full Text] [PDF]

				P. Cayirlioglu, P. C. Bonnette, M. R. Dickson, and R. J. Duronio Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells Development, December 15, 2001; 128(24): 5085 - 5098. [Abstract] [Full Text] [PDF]

				M. V. Frolov, D. S. Huen, O. Stevaux, D. Dimova, K. Balczarek-Strang, M. Elsdon, and N. J. Dyson Functional antagonism between E2F family members Genes & Dev., August 15, 2001; 15(16): 2146 - 2160. [Abstract] [Full Text] [PDF]

				D. Myster, P. Bonnette, and R. Duronio A role for the DP subunit of the E2F transcription factor in axis determination during Drosophila oogenesis Development, January 8, 2000; 127(15): 3249 - 3261. [Abstract] [PDF]