Akazawa, C., Ishibashi, M., Shimizu, C., Naknish, S. and Kageyama, R (1995). A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system. J. Biol. Chem 270, 8730-8738.[Abstract/Free Full Text]
Balak, K. J., Corwin, J. T. and Jones, J. E (1990). Regenerated hair cells can originate from supporting cell progeny: evidence from phototoxicity and laser ablation experiments in the lateral line system. J. Neurosci 10, 2502-2512.[Abstract]
Ben-Arie, N., Bellen, H., Armstrong, D., McCall, A., Gordadze, P., Guo, Q., Matzuk, M. and Zoghbi, H (1997). Math1 is essential for genesis of cerebellar granule neurons. Nature 390, 169-172.[Medline]
Bermingham, N. A., Hassan, B. A., Price, S. D., Vollrath, M. A., Ben-Arie, N., Eatock, R. A., Bellen, H. J., Lysakowski, A. and Zoghbi, H. Y (1999). Math1: an essential gene for the generation of inner ear hair cells. Science 284, 1837-1841.[Abstract/Free Full Text]
Chen, P. and Segil, N (1999). p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti. Development 126, 1581-1590.[Abstract]
Corwin, J. and Cotanche, D (1988). Regeneration of sensory hair cells after acoustic trauma. Science 240, 1772-1774.[Abstract/Free Full Text]
Corwin, J. T. and Warchol, M. E (1991). Auditory hair cells: structure, function, development, and regeneration. Annu. Rev. Neurosci 14, 301-333.[Medline]
Corwin, J. T., Warchol, M. E., Saffer, L. D., Finley, J. E., Gu, R. and Lamber, P. R (1996). Growth factors as potential drugs for the sensory epithelia of the ear. Ciba Found. Symp 196, 167-187.[Medline]
Fekete, D. M (1996). Cell fate specification in the inner ear. Curr. Opin. Neurobiol 6, 533-541.[Medline]
Fekete, D. M (1999). Development of the vertebrate ear: insights from knockouts and mutants. Trends Neurosci 22, 263-269.[Medline]
Fekete, D. M., Muthukumar, S. and Karagogeos, D (1998). Hair cells and supporting cells share a common progenitor in the avian inner ear. J. Neurosci 18, 7811-7821.[Abstract/Free Full Text]
Forge, A., Li, L., Corwin, J. T. and Nevill, G (1993). Ultrastructural evidence for hair cell regeneration in the mammalian inner ear. Science 259, 1616-1619.[Abstract/Free Full Text]
Gibson, U. E., Heid, C. A. and Williams, P. M (1996). A novel method for real time quantitative RT-PCR. Genome Res 6, 995-1001.[Abstract/Free Full Text]
Haddon, C., Jiang, Y. J., Smithers, L. and Lewis, J (1998). Delta-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: evidence from the mind bomb mutant. Development 125, 4637-4644.[Abstract]
Helms, A. and Johnson, J (1998). Progenitors of dorsal commissural interneurons are defined by MATH1 expression. Development 125, 919-928.[Abstract]
Hsieh, J., Nofziger, D., Weinmaster, G. and Hayward, S (1997). Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation. J. Virol 71, 1938-1945.[Abstract]
Hynes, M., Poulsen, K., Tessier-Lavigne, M. and Rosenthal, A (1995). Control of neuronal diversity by the floor plate: contact-mediated induction of midbrain dopaminergic neurons. Cell 80, 95-101.[Medline]
Ishibashi, M., Ang, S., Shiota, K., Nakanishi, S., Kageyama, R. and Guillemot, F (1995). Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis,and severe neural tube defects. Genes Dev 15, 3136-3148.
Jarriault, S., Brou, C., Logeat, F., Schroeter, E., Kopan, R. and Israel, A (1995). Signalling downstream of activated mammalian Notch. Nature 377, 355-358.[Medline]
Jarriault, S., Le Bail, O., Hirsinger, E., Pourquie, O., Logeat, F., Strong, C., Brou, C., Seidah, N. and Israel, A (1998). Delta-1 activation of notch-1 signaling results in HES-1 transactivation. Mol. Cell. Biol 18, 7423-7431.[Abstract/Free Full Text]
Kageyama, R. and Nakanishi, S (1997). Helix-loop-helix factor in growth and differentiation of vertebrate nervous system. Curr. Opin. Genet. Dev 7, 659-665.[Medline]
Kuntz, A. L. and Oesterle, E. C (1998). Transforming growth factor alpha with insulin stimulates cell proliferation in vivo in adult rat vestibular sensory epithelium. J. Comp. Neurol 399, 413-423.[Medline]
Lambert, P (1994). Inner ear hair cell regeneration in a mammal: identification of a triggering factor. Laryngoscope 104, 701-717.[Medline]
Lanford, P. J., Lan, Y., Jiang, R., Lindsell, C., Weinmaster, G., Gridley, T. and Kelley, M. W (1999). Notch signalling pathway mediates hair cell development in mammalian cochlea. Nat. Genet 21, 289-292.[Medline]
Lewis, A. K., Frantz, G. D., Carpenter, D. A., de Sauvage, F. J. and Gao, W. Q (1998). Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear. Mech. Dev 78, 159-163.[Medline]
Lewis, J (1991). Rules for the production of sensory cells. Ciba Found. Symp 160, 25-53.[Medline]
Li, L. and Forge, A (1997). Morphological evidence for supporting cell to hair cell conversion in the mammalian utricular macula. Int. J. Dev. Neurosci 15, 433-446.[Medline]
Lowenheim, H., Furness, D. N., Kil, J., Zinn, C., Gultig, K., Fero, M. L., Frost, D., Gummer, A. W., Roberts, J. M., Rubel, E. W., Hackney, C. M. and Zenner, H. P (1999). Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti. Proc. Nat. Acad. Sci. USA 96, 4084-4088.[Abstract/Free Full Text]
McLarren, K., Lo, R., Grbavec, D., Thirunavukkarasu, K., Karsenty, G. and Stifani, S (2000). The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1. J. Biol. Chem 275, 530-538.[Abstract/Free Full Text]
Morrison, A., Hodgetts, C., Gossler, A., Hrabe de Angelis, M. and Lewis, J (1999). Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear. Mech. Dev 84, 169-172.[Medline]
Murone, M., Rosenthal A and de Sauvage, F. J (1999). Sonic hedgehog signaling by the patched-smoothened receptor complex. Curr. Biol 28, 76-84.
Nakamura, Y., Sakakibara, S.-i., Miyata, T., Ogawa, M., Shimazaki, T., Weiss, S., Kageyama, R. and Okano, H (2000). The bHLH gene Hes1 as a repressor of the neuronal commitment of CNS stem cells. J. Neurosci 20, 283-293.[Abstract/Free Full Text]
Navaratnam, D. S., Su, H. S., Scott, S. P. and Oberholtzer, J. C (1996). Proliferation in the auditory receptor epithelium mediated by a cyclic AMP-dependent signaling pathway. Nat. Med 2, 1136-1139.[Medline]
Nishimura, M., Isaka, F., Ishibashi, M., Tomita, K., Tsuda, H., Nakanishi, S. and Kageyama, R (1998). Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of split. Genomics 49, 69-75.[Medline]
Oesterle, E. C., Tsue, T. T. and Rubel, E. W (1997). Induction of cell proliferation in avian inner ear sensory epithelia by insulin-like growth factor-I and insulin. J. Comp. Neurol 380, 262-274.[Medline]
Ohsako, S., Hyer, J., Panganiban, G., Oliver, I. and Caudy, M (1994). Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation. Genes Dev 8, 2743-2755.[Abstract/Free Full Text]
Ohtsuka, T., Ishibashi, M., Gradwohl, G., Nakanishi, S., Guillemot, F. and Kageyama, R (1999). Hes1 and Hes5 as Notch effectors in mammalian neuronal differentiation. EMBO J 18, 2196-2207.[Medline]
Paroush, Z., Finley, R. J., Kidd, T., Wainwright, S., Ingham, P., Brent, R. and Ish-Horowicz, D (1994). Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell 79, 805-815.[Medline]
Ryals, B. M. and Rubel, E. W (1988). Hair cell regeneration after acoustic trauma in adult Coturnix quail. Science 240, 1774-1776.[Abstract/Free Full Text]
Sans, A. and Chat, M (1982). Analysis of temporal and spatial patterns of rat vestibular hair cell differentiation by tritiated thymidine radioautography. J. Comp. Neurol 206, 1-8.[Medline]
Sasai, Y., Kageyama, R., Tagawa, Y., Shigemoto, R. and Nakanishi, S (1992). Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev 6, 2620-2634.[Abstract/Free Full Text]
Shailam, R., Lanford, P. J., Dolinsky, C. M., Norton, C. R., Gridley, T. andKelley, M. W (1999). Expression of proneural and neurogenic genes in the embryonic mammalian vestibular system. J. Neurocytol 28, 809-819.[Medline]
Staecker, H. and Van De Water, T (1998). Factors controlling hair-cell regeneration/repair in the inner ear. Curr. Opin. Neurobiol 8, 480-487.[Medline]
Stone, J. S. and Rubel, E. W (1999). Delta1 expression during avian hair cell regeneration. Development, 126, 961-973.[Abstract]
Tomita, K., Ishibashi, M., Nakahara, K., Ang, S., Nakanishi, S., Guillemot, F. and Kageyama, R (1996). Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis. Neuron, 16, 723-734.[Medline]
Van Doren, M., Bailey, A., Esnayra, J., Ede, K. and Posakony, J (1994). Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete. Genes Dev 8, 2729-2742.[Abstract/Free Full Text]
Wang, S., Sdrulla, A., diSibio, G., Bush, G., Nofziger, D., Hicks, C., Weinmaster, G. and Barres, B (1998). Notch receptor activation inhibits oligodendrocyte differentiation. Neuron 21, 63-75.[Medline]
Warchol, M. E., Lambert, P. R., Goldstein, B. J., Forge, A. and Corwin, J. T (1993). Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans. Science 259, 1619-1622.[Abstract/Free Full Text]
Xiang, M., Gan, L., Li, D., Chen, Z. Y., Zhou, L., O'Malley, B. W., Jr, Klein, W. and Nathans, J (1997). Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc. Natl. Acad. Sci. USA 94, 9445-9450.[Abstract/Free Full Text]
Xiang, M., Gao, W.-Q., Hasson, T. and Shin, J. J (1998). Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development 125, 3935-3946.[Abstract]
Yamashita, H. and Oesterle, E. C (1995). Induction of cell proliferation inmammalian inner-ear sensory epithelia by transforming growth factor alpha and epidermal growth factor. Proc. Nat. Acad. Sci. USA 92, 3152-3155.[Abstract/Free Full Text]
Zhang, N., Martin, G.V., Kelley, M.W. and Gridley, T (2000). A mutation in the lunatic fringe gene suppresses the effects of a jagged2 mutation on inner hair cell development in the cochlea. Curr. Biol 10, 659-662.[Medline]
Zheng, J. L. and Gao, W.-Q (1996). Differential damage to auditory neurons and hair cells by ototoxins and neuroprotection by specific neurotrophins in rat cochlear organotypic cultures. Eur. J. Neurosci 8, 1897-1905.[Medline]
Zheng, J. L. and Gao, W.-Q (1997). Analysis of rat vestibular hair cell development and regeneration using calretinin as an early marker. J. Neurosci 17, 8270-8282.[Abstract/Free Full Text]
Zheng, J. L. and Gao, W.-Q (1999). Concanavalin A protects hair cells against gentamicin ototoxicity in rat cochlear explant cultures. J. Neurobiol 39, 29-40.[Medline]
Zheng, J. L., Helbig, C. and Gao, W.-Q (1997). Induction of cell proliferation by fibroblast and insulin-like growth factors in pure rat inner ear epithelial cell cultures. J. Neurosci 17, 216-226.[Abstract/Free Full Text]
Zheng, J., Frantz, G., Lewis, A., Sliwkowski, M. and Gao, W.-Q (1999). Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage. J. Neurocytol 28, 901-912.[Medline]
Zheng, J. L., Keller, G. and Gao, W.-Q (1999). Immunocytochemical and morphological evidence for intracellular self-repair as an important contributor to mammalian hair cell recovery. J. Neurosci 19, 2161-2170.[Abstract/Free Full Text]
Zine, A., Van De Water T.R. and de Ribaupierre, F (2000). Notch signaling regulates the pattern of auditory hair cell differentiation in mammals. Development 127, 3373-3383.[Abstract]
