Regulation of Drosophila wing vein patterning: net encodes a bHLH protein repressing rhomboid and is repressed by rhomboid-dependent Egfr signalling

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Brentrup, D.
	Articles by Noll, M.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Brentrup, D.
	Articles by Noll, M.


Social Bookmarking

	What's this?

Alifragis, P., Poortinga, G., Parkhurst, S. M. and Delidakis, C (1997). A network of interacting transcriptional regulators involved in Drosophila neural fate specification revealed by the yeast two-hybrid system. Proc. Natl. Acad. Sci. USA 94, 13099-13104.[Abstract/Free Full Text]

Altschul, S. F., Gish, W., Miller, W., Myers, E. W. and Lipman, D. J (1990). Basic local alignment search tool. J. Mol. Biol 215, 403-410.[Medline]

Artavanis-Tsakonas, S. and Simpson, P (1991). Choosing a cell fate: a view from the Notch locus. Trends Genet 7, 403-408.[Medline]

Artavanis-Tsakonas, S., Muskavitch, M. A. T. and Yedvobnick, B (1983). Molecular cloning of Notch , a locus affecting neurogenesis in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 80, 1977-1981.[Abstract/Free Full Text]

Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M. E (1995). Notch signaling. Science 268, 225-232.[Abstract/Free Full Text]

Barolo, S. and Levine, M (1997). hairy mediates dominant repression in the Drosophila embryo. EMBO J 16, 2883-2891.[Medline]

Biehs, B., Sturtevant, M. A. and Bier, E (1998). Boundaries in the Drosophila wing imaginal disc organize vein-specific genetic programs. Development 125, 4245-4257.[Abstract]

Bier, E (1998). Localized activation of RTK/MAPK pathways during Drosophila development. BioEssays 20, 189-194.[Medline]

Bier, E., Jan, L. Y. and Jan, Y. N (1990). rhomboid , a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes Dev 4, 190-203.[Abstract/Free Full Text]

Brand, A. H. and Perrimon, N (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.[Abstract]

Campos-Ortega, J. A (1997). Neurogenesis in Drosophila : an historical perspective and some prospects. Perspect. Dev. Neurobiol 4, 267-271.[Medline]

Campuzano, S., Carramolino, L., Cabrera, C. V., Ru\222z-Gomez, M., Villares, R., Boronat, A. and Modolell, J (1985). Molecular genetics of the achaete-scute gene complex of D. melanogaster. Cell 40, 327-338.[Medline]

Cowell, I. G (1994). Repression versus activation in the control of gene transcription. Trends Biochem. Sci 19, 38-42.[Medline]

Cubadda, Y., Heitzler, P., Ray, R. P., Bourouis, M., Ramain, P., Gelbart, W., Simpson, P. and Haenlin, M (1997). u-shaped encodes a zinc finger protein that regulates the proneural genes achaete and scute during the formation of bristles in Drosophila. Genes Dev 11, 3083-3095.[Abstract/Free Full Text]

Dawson, S. R., Turner, D. L., Weintraub, H. and Parkhurst, S. M (1995). Specificity for the hairy/enhancer of split basic helix-loop-helix (bHLH) proteins maps outside the bHLH domain and suggests two separable modes of transcriptional repression. Mol. Cell. Biol 15, 6923-6931.[Abstract]

de Celis, J. F., Llimargas, M. and Casanova, J (1995). ventral veinless , the gene encoding the Cf1a transcription factor, links positional information and cell differentiation during embryonic and imaginal development in Drosophila melanogaster. Development 121, 3405-3416.[Abstract]

de Celis, J. F., de Celis, J., Ligoxygakis, P., Preiss, A., Delidakis, C. and Bray, S (1996). Functional relationship between Notch , Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development. Development 122, 2719-2728.[Abstract]

de Celis, J. F., Bray, S. and Garc\222a-Bellido, A (1997). Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing. Development 124, 1919-1928.[Abstract]

Delidakis, C. and Artavanis-Tsakonas, S (1992). The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins. Proc. Natl. Acad. Sci. USA 89, 8731-8735.[Abstract/Free Full Text]

D\222az-Benjumea, F. J. and Garc\222a-Bellido, A (1990). Behavior of cell mutant for an EGF receptor homologue of Drosophila in genetic mosaics. Proc. R. Soc. London Biol. Sci 242, 36-44.[Medline]

D\222az-Benjumea, F. J. and Cohen, S. M (1993). Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila. Cell 75, 741-752.[Medline]

Ferre-D'Amare, A. R., Prendergast, G. C., Ziff, E. B. and Burley, S. K (1993). Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature 363, 38-45.[Medline]

Fisher, A. L., Ohsako, S. and Caudy, M (1996). The WRPW motif of the hairy -related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain. Mol. Cell. Biol 16, 2670-2677.[Abstract]

Frei, E., Baumgartner, S., Edstr\232m, J.-E. and Noll, M (1985). Cloning of the extra sex combs gene of Drosophila and its identification by P-element-mediated gene transfer. EMBO J 4, 979-987.[Medline]

Fristrom, D., Gotwals, P., Eaton, S., Kornberg, T. B., Sturtevant, M., Bier, E. and Fristrom, J. W (1994). blistered : a gene required for vein/intervein formation in wings of Drosophila. Development 120, 2661-2671.[Abstract/Free Full Text]

Fu, W. and Noll, M (1997). The Pax2 homolog sparkling is required for development of cone and pigment cells in the Drosophila eye. Genes Dev 11, 2066-2078.[Abstract/Free Full Text]

Gabay, L., Seger, R. and Shilo, B.-Z (1997). In situ activation pattern of Drosophila EGF receptor pathway during development. Science 277, 1103-1106.[Abstract/Free Full Text]

Garc\222a-Bellido, A. and de Celis, J. F (1992). Developmental genetics of the venation pattern of Drosophila. Annu. Rev. Genet 26, 277-304.[Medline]

Guichard, A., Biehs, B., Sturtevant, M. A., Wickline, L., Chacko, J., Howard, K. and Bier, E (1999). rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development. Development 126, 2663-2676.[Abstract]

Guillen, I., Mullor, J. L., Capdevila, J., Sanchez-Herrero, E., Morata, G. and Guerrero, I (1995). The function of engrailed and the specification of Drosophila wing pattern. Development 121, 3447-3456.[Abstract]

Hanna-Rose, W. and Hansen, U (1996). Active repression mechanisms of eukaryotic transcription repressors. Trends Genet 12, 229-234.[Medline]

Hidalgo, A (1994). Three distinct roles for the engrailed gene in Drosophila wing development. Curr. Biol 4, 1087-1098.[Medline]

Hidalgo, A (1998). Growth and patterning from the engrailed interface. Int. J. Dev. Biol 42, 317-324.[Medline]

Horimoto, K., Yamamoto, H., Yanagi, K., Ohshima, K. and Otsuka, J (1994). A simple procedure for assigning a sequence motif with an obscure pattern: application to the basic/helix-loop-helix motif. Protein Eng 7, 1433-1440.[Abstract/Free Full Text]

Ishibashi, M., Moriyoshi, K., Sasai, Y., Shiota, K., Nakanishi, S. and Kageyama, R (1994). Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system. EMBO J 13, 1799-1805.[Medline]

Jimenez, G., Paroush, Z. and Ish-Horowicz, D (1997). Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed. Genes Dev 11, 3072-3082.[Abstract/Free Full Text]

Karim, F. D. and Rubin, G. M (1998). Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues. Development 125, 1-9.[Abstract]

Kilchherr, F., Baumgartner, S., Bopp, D., Frei, E. and Noll, M (1986). Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis. Nature 321, 493-499.

Klemenz, R., Weber, U. and Gehring, W. J (1987). The white gene as a marker in a new P-element vector for gene transfer in Drosophila. Nucleic Acids Res 15, 3947-3959.[Abstract/Free Full Text]

Knust, E., Schrons, H., Grawe, F. and Campos-Ortega, J. A (1992). Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins. Genetics 132, 505-518.[Abstract]

Kornberg, T., Siden, I., O'Farrell, P. and Simon, M (1985). The engrailed locus of Drosophila : in situ localization of transcripts reveals compartment-specific expression. Cell 40, 45-53.[Medline]

Lawrence, P. A. and Morata, G (1976). Compartments in the wing of Drosophila : A study of the engrailed gene. Dev. Biol 50, 321-337.[Medline]

Lecuit, T., Brook, J., Ng, M., Calleja, M., Sun, H. and Cohen, S. M (1996). Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing. Nature 381, 387-393.[Medline]

Lunde, K., Biehs, B., Nauber, U. and Bier, E (1998). The knirps and knirps-related genes organize development of the second wing vein in Drosophila. Development 125, 4145-4154.[Abstract]

Matakatsu, H., Tadokoro, R., Gamo, S. and Hayashi, S (1999). Repression of the wing vein development in Drosophila by the nuclear matrix protein Plexus. Development 126, 5207-5216.[Abstract]

Mechler, B. M., McGinnis, W. and Gehring, W. J (1985). Molecular cloning of lethal(2)giant larvae , a recessive oncogene of Drosophila melanogaster. EMBO J 4, 1551-1557.[Medline]

Mil\207n, M., Baonza, A. and Garc\222a-Bellido, A (1997). Wing surface interactions in venation patterning in Drosophila. Mech. Dev 67, 203-213.[Medline]

Mil\207n, M., D\222az-Benjumea, F. J. and Cohen, S. M (1998). Beadex encodes an LMO protein that regulates Apterous LIM-homeodomain activity in Drosophila wing development: a model for LMO oncogene function. Genes Dev 12, 2912-2920.[Abstract/Free Full Text]

Montagne, J., Groppe, J., Guillemin, K., Krasnow, M. A., Gehring, W. J. and Affolter, M (1996). The Drosophila Serum Response Factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered. Development 122, 2589-2597.[Abstract]

Murre, C., Bain, G., van Dijk, M. A., Engel, I., Furnari, B. A., Massari, M. E., Matthews, J. R., Quong, M. W., Rivera, R. R. and Stuiver, M. H (1994). Structure and function of helix-loop-helix proteins. Biochim. Biophys. Acta 1218, 129-135.[Medline]

Nellen, D., Burke, R., Struhl, G. and Basler, K (1996). Direct and long-range action of a DPP morphogen gradient. Cell 85, 357-368.[Medline]

Noll, M (1993). Evolution and role of Pax genes. Curr. Opin. Genet. Dev 3, 595-605.[Medline]

Noll, R., Sturtevant, M. A., Gollapudi, R. R. and Bier, E (1994). New funtions of the Drosophila rhomboid gene during embryonic and adult development are revealed by a novel genetic method, enhancer piracy. Development 120, 2329-2338.[Abstract]

Ohsako, S., Hyer, J., Panganiban, G., Oliver, I. and Caudy, M (1994). Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation. Genes Dev 8, 2743-2755.[Abstract/Free Full Text]

Paroush, Z., Finley, R. L., Jr, Kidd, T., Wainwright, S. M., Ingham, P. W., Brent, R. and Ish-Horowicz, D (1994). Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with Hairy-related bHLH proteins. Cell 79, 805-815.[Medline]

Phillips, S. E (1994). Built by association: structure and function of helix-loop-helix DNA-binding proteins. Structure 2, 1-4.[Abstract/Free Full Text]

Roch, F., Baonza, A., Mart\222n-Blanco, E. and Garc\222a-Bellido, A (1998). Genetic interactions and cell behaviour in blistered mutants duringproliferation and differentiation of the Drosophila wing. Development 125, 1823-1832.[Abstract]

R\277rth, P (1996). A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. Proc. Natl. Acad. Sci. USA 93, 12418-12422.[Abstract/Free Full Text]

Rubin, G. M. and Spradling, A. C (1982). Genetic transformation of Drosophila with transposable element vectors. Science 218, 348-353.[Abstract/Free Full Text]

Schneitz, K., Spielmann, P. and Noll, M (1993). Molecular genetics of aristaless , a prd -type homeo box gene involved in the morphogenesis of proximal and distal pattern elements in a subset of appendages in Drosophila. Genes Dev 7, 114-129.[Abstract/Free Full Text]

Schnepp, B., Grumbling, G., Donaldson, T. and Simcox, A (1996). Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins. Genes Dev 10, 2302-2313.[Abstract/Free Full Text]

Simcox, A (1997). Differential requirement for EGF-like ligands in Drosophila wing development. Mech. Dev 62, 41-50.[Medline]

Simcox, A. A., Grumbling, G., Schnepp, B., Bennington-Mathias, C., Hersperger, E. and Shearn, A (1996). Molecular, phenotypic, and expression analysis of vein , a gene required for growth of the Drosophila wing disc. Dev. Biol 177, 475-489.[Medline]

Sturtevant, M. A. and Bier, E (1995). Analysis of the genetic hierarchy guiding wing vein development in Drosophila. Development 121, 785-801.[Abstract]

Sturtevant, M. A., Roark, M. and Bier, E (1993). The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway. Genes Dev 7, 961-973.[Abstract/Free Full Text]

Sturtevant, M. A., O'Neill, J. W. and Bier, E (1994). Down-regulation of Drosophila Egf-r mRNA levels following hyperactivated receptor signaling. Development 120, 2593-2600.[Abstract/Free Full Text]

Sturtevant, M. A., Biehs, B., Marin, E. and Bier, E (1997). The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing. Development 124, 21-32.[Abstract]

Tabata, T. and Kornberg, T. B (1994). Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.[Medline]

Tabata, T., Schwartz, C., Gustavson, E., Ali, Z. and Kornberg, T. B (1995). Creating a Drosophila wing de novo, the role of engrailed , and the compartment border hypothesis. Development 121, 3359-3369.[Abstract]

Tautz, D. and Pfeifle, C (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.[Medline]

Worley, K. C., Wiese, B. A. and Smith, R. F (1995). BEAUTY: an enhanced BLAST-based search tool that integrates multiple biological information resources into sequence similarity search results. Genome Res 5, 173-184.[Abstract/Free Full Text]

Yu, K., Sturtevant, M. A., Biehs, B., Fran\215ois, V., Padgett, R. W., Blackman, R. K. and Bier, E (1996). The Drosophila decapentaplegic and short gastrulation genes function antagonistically during adult wing vein development. Development 122, 4033-4044.[Abstract]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

M. Angulo, M. Corominas, and F. Serras
Activation and repression activities of ash2 in Drosophila wing imaginal discs
Development, October 15, 2004; 131(20): 4943 - 4953.
[Abstract] [Full Text] [PDF]

H. Araujo, E. Negreiros, and E. Bier
Integrins modulate Sog activity in the Drosophila wing
Development, August 15, 2003; 130(16): 3851 - 3864.
[Abstract] [Full Text] [PDF]

L. Michaut, S. Flister, M. Neeb, K. P. White, U. Certa, and W. J. Gehring
Analysis of the eye developmental pathway in Drosophila using DNA microarrays
PNAS, April 1, 2003; 100(7): 4024 - 4029.
[Abstract] [Full Text] [PDF]

A. Stathopoulos and M. Levine
Linear signaling in the Toll-Dorsal pathway of Drosophila: activated Pelle kinase specifies all threshold outputs of gene expression while the bHLH protein Twist specifies a subset
Development, March 9, 2003; 129(14): 3411 - 3419.
[Abstract] [Full Text] [PDF]

V. Ledent and M. Vervoort
The Basic Helix-Loop-Helix Protein Family: Comparative Genomics and Phylogenetic Analysis
Genome Res., May 1, 2001; 11(5): 754 - 770.
[Abstract] [Full Text]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Brentrup, D.

Articles by Noll, M.

Search for Related Content

PubMed

PubMed Citation

Articles by Brentrup, D.

Articles by Noll, M.

Social Bookmarking

What's this?

				H. Araujo, E. Negreiros, and E. Bier Integrins modulate Sog activity in the Drosophila wing Development, August 15, 2003; 130(16): 3851 - 3864. [Abstract] [Full Text] [PDF]

				L. Michaut, S. Flister, M. Neeb, K. P. White, U. Certa, and W. J. Gehring Analysis of the eye developmental pathway in Drosophila using DNA microarrays PNAS, April 1, 2003; 100(7): 4024 - 4029. [Abstract] [Full Text] [PDF]

				A. Stathopoulos and M. Levine Linear signaling in the Toll-Dorsal pathway of Drosophila: activated Pelle kinase specifies all threshold outputs of gene expression while the bHLH protein Twist specifies a subset Development, March 9, 2003; 129(14): 3411 - 3419. [Abstract] [Full Text] [PDF]

				V. Ledent and M. Vervoort The Basic Helix-Loop-Helix Protein Family: Comparative Genomics and Phylogenetic Analysis Genome Res., May 1, 2001; 11(5): 754 - 770. [Abstract] [Full Text]