Artavanis-Tsakonas, S (1997). Alagille syndrome \320 a notch up for the Notch receptor. Nat. Genet 16, 212-213.[Medline]
Artavanis-Tsakonas, S., Rand, M. D. and Lake, R. J (1999). Notch signalling: Cell fate control and signal integration in development. Science 284, 770-775.[Abstract/Free Full Text]
Bellen, H. J., O'Kane, C. J., Wilson, C., Grossniklaus, U., Pearson, R. K. and Gehring, W. J (1989). P-element mediated enhancer detection; a versatile method to study development in Drosophila. Genes Dev 3, 1288-1300.[Abstract/Free Full Text]
Blaumueller, C. M., Qi, H., Zagouras, P. and Artavanis-Tsakonas, S (1997). Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell 90, 281-291.[Medline]
Brand, A. H. and Perrimon, N (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.[Abstract]
Bray, S (1998). A Notch affair. Cell 93, 499-503.[Medline]
Cagan, R. L. and Ready, D. F (1989). Notch is required for successive cell decisions in the developing Drosophila retina. Genes Dev 3, 1099-1112.[Abstract/Free Full Text]
Chan, Y.-M. and Jan, Y. N (1998). Roles for proteolysis and trafficking in Notch maturation and signal transduction. Cell 94, 423-426.[Medline]
Chitnis, A., Henrique, D., Lewis, J., Ish-Horowicz, D. and Kintner, C (1995). Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature 375, 761-766.[Medline]
de Celis, J. F., Bray, S. and Garc\222a-Bellido, A (1997). Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing. Development 124, 1919-1928.[Abstract]
Diederich, R. J., Matsuno, K., Hing, H. and Artavanis-Tsakonas, S (1994). Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signalling pathway. Development 120, 473-481.[Abstract]
Egan, S. E., St-Pierre, B. and Leow, C. C (1998). Notch receptors, partners, and regulators: from conserved domains to powerful functions. Curr. Top. Microbiol. Immunol 228, 274-324.
Ellisen, L. W., Bird, J., West, D. C., Soreng, A. L., Reynolds, T. C., Smith, S. D. and Sklar, J (1991). TAN-1 , the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66, 649-661.[Medline]
Fehon, R. G., Kooh, P. J., Rebay, I., Regan, C. L., Xu, T., Muskavitch, M. A. T. and Artavanis-Tsakonas, S (1990). Molecular interactions between the protein products of the neurogenic loci Notch and Delta , two EGF homologous genes in Drosophila. Cell 61, 523-534.[Medline]
Fleming, R. J., Gu, Y. and Hukriede, N. A (1997). Serrate-mediated activation of Notch is specifically blocked by the product of the gene Fringe in the dorsal compartment of the Drosophila wing imaginal disc. Development 124, 2973-2981.[Abstract]
Gallyas, F., G\232res, T. and Merchenthaler, I (1982). High-grade intensification of the end-product of the diaminobenzidine reaction for peroxidase histochemistry. J. Histochem. Cytochem 30, 183-184.[Abstract]
Greenwald, I (1998). LIN-12/Notch signaling: lessons from worms and flies. Genes Dev 124, 1751-1762.
Haenlin, M., Kramatschek, B. and Campos-Ortega, J. A (1990). The pattern of transcription of the neurogenic gene Delta of Drosophila melanogaster. Development 110, 905-914.[Abstract/Free Full Text]
Heldin, C.-H (1995). Dimerization of cell surface receptors in signal transduction. Cell 80, 213-223.[Medline]
Henderson, S. T., Gao, D., Christenson, S. and Kimble, J (1997). Functional domains of LAG-2, a putative signaling ligand for LIN-12 andGLP-1 receptors in Caenorhabditis elegans. Mol. Biol. Cell 8, 1751-1762.[Abstract]
Huppert, S. S., Jacobsen, T. L. and Muskavitch, M. A. T (1997). Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis. Development 124, 3283-3291.[Abstract]
Jacobsen, T. L., Brennan, K., Arias, A. M. and Muskavitch, M. A. T (1998). Cis -interactions between Delta and Notch modulate neurogenic signalling in Drosophila. Development 125, 4531-4540.[Abstract]
Jarriault, S., Brou, C., Logeat, F., Schroeter, E. H., Kopan, R. and Israel, A (1995). Signalling downstream of activated mammalian Notch. Nature 377, 355-358.[Medline]
Jen, W. C., Wettstein, D., Turner, D., Chitnis, A. and Kintner, C (1997). The Notch ligand, X-Delta-2, mediates segmentation of the paraxial mesoderm in Xenopus embryos. Development 124, 1169-1178.[Abstract]
Jiang, R., Lan, Y., Chapman, H. D., Shawber, C., Norton, C. R., Serreze, D. V., Weinmaster, G. and Gridley, T (1998). Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev 12, 1046-1057.[Abstract/Free Full Text]
Kimble, J., Henderson, S. and Crittenden, S (1998). Notch/Lin-12 signaling: transduction by regulated protein slicing. Trends Biochem. Sci 23, 353-357.[Medline]
Klein, T. and Arias, A. M (1998). Interactions among Delta, Serrate and Fringe modulate Notch activity during Drosophila wing development. Development 125, 2951-2962.[Abstract]
Klueg, K. M. and Muskavitch, M. A. T (1999). Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signalling pathway in Drosophila. J. Cell Sci 112, 3289-3297.[Abstract]
Klueg, K. M., Parody, T. R. and Muskavitch, M. A. T (1998). Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development. Mol. Biol. Cell 9, 1709-1723.[Abstract/Free Full Text]
Kooh, P. J., Fehon, R. G. and Muskavitch, M. A. T (1993). Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development 117, 493-507.[Abstract]
Kopan, R., Schroeter, E. H., Weintraub, H. and Nye, J. S (1996). Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc. Natl. Acad. Sci. USA 93, 1683-1688.[Abstract/Free Full Text]
Kopczynski, C. C., Alton, A. K., Fechtel, K., Kooh, P. J. and Muskavitch, M. A (1988). Delta , a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factors of vertebrates. Genes Dev 2, 1723-1735.[Abstract/Free Full Text]
Kr\212mer, H. and Phistry, M (1996). Mutations in the Drosophila hook gene inhibit endocytosis of the Boss transmembrane ligand into multivesicular bodies. J. Cell Biol 133, 1205-1216.[Abstract/Free Full Text]
Kr\212mer, H. and Phistry, M (1999). Genetic analysis of hook , a gene required for endocytic trafficking in Drosophila. Genetics 151, 675-684.[Abstract/Free Full Text]
Lecourtois, M. and Schweisguth, F (1998). Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos. Curr. Biol 8, 771-774.[Medline]
Lieber, T., Kidd, S., Alcamo, E., Corbin, V. and Young, M. W (1993). Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev 7, 1949-1965.[Abstract/Free Full Text]
Lieber, T., Wesley, C., Alcamo, E., Hassel, B., Krane, J., Campos-Ortega, J. A. and Young, M. W (1992). Single amino acid substitutions in EGF-like elements of Notch and Delta modify Drosophila development and affect cell adhesion in vitro. Neuron 9, 847-859.[Medline]
Liposits, Z. S., Set\207lo, G. Y. and Lerko, B. F (1984). Application of the silver-gold intensified 3,3-diaminobenzidine chromatin to the light and electron microscopic detection of the luteinizing hormone-releasing hormone system of the rat brain. Neurosci 13, 513-525.[Medline]
Lissemore, J. L. and Starmer, W. T (1999). Phylogenetic analysis of vertebrate and invertebrate Delta/Serrate/LAG-2 (DSL) proteins. Molec. Phylog. Evol 11, 308-319.[Medline]
Logeat, F., Bessia, C., Brou, B., LeBail, O., Jarriault, S., Seidah, N. G. and Isra\221l, A (1998). The Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc. Natl. Acad. Sci. USA 95, 8108-8112.[Abstract/Free Full Text]
McNiven, M. A (1998). Dynamin: A molecular motor with pinchase action. Cell 94, 151-154.[Medline]
Muskavitch, M. A. T (1994). Delta-Notch signaling and Drosophila cell fate choice. Dev. Biol 166, 415-430.[Medline]
Parks, A. L., Huppert, S. S. and Muskavitch, M. A. T (1997). The dynamics of neurogenic signalling underlying bristle development in Drosophila melanogaster. Mech. Dev 63, 61-74.[Medline]
Parks, A. L. and Muskavitch, M. A. T (1993). Delta function is required for bristle organ determination and morphogenesis in Drosophila. Dev. Biol 157, 484-496.[Medline]
Parks, A. L., Turner, F. R. and Muskavitch, M. A. T (1995). Relationships between complex Delta expression and the specification of retinal cell fates during Drosophila eye development. Mech. Dev 50, 201-216.[Medline]
Parody, T. R. and Muskavitch, M. A. T (1993). The pleiotropic function of Delta during postembryonic development of Drosophila melanogaster. Genetics 135, 527-539.[Abstract]
Poodry, C. A (1990). shibire , a neurogenic mutant of Drosophila. Dev. Biol 138, 464-472.[Medline]
Poodry, C. A., Hall, L. and Suzuki, D. T (1973). Developmental properties of shibirets : A pleiotropic mutation affecting larval and adult locomotion and development. Dev. Biol 32, 373-386.[Medline]
Qi, H., Rand, M. D., Wu, X., Sestan, N., Wang, W., Rakic, P., Xu, T. and Artavanis-Tsakonas, S (1999). Processing of the Notch ligand Delta by the metalloprotease Kuzbanian. Science 283, 91-94.[Abstract/Free Full Text]
Rebay, I., Fleming, R. J., Fehon, R. G., Cherbas, L. F., Cherbas, P. T. and Artavanis-Tsakonas, S (1991). Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell 67, 687-699.[Medline]
Rooke, J., Pan, D., Xu, T. and Rubin, G. M (1996). KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis. Science 273, 1227-1231.[Abstract]
Schmid, S. L., McNiven, M. A. and Camilli, P. D (1998). Dynamin and its partners: a progress report. Curr. Opin. Cell Biol 10, 504-512.[Medline]
Schneider, I (1972). Cell lines derived from late embryonic stages of Drosophila melanogaster. J. Embryol. Exp. Morph 27, 353-365.[Medline]
Schroeter, E. H., Kissinger, J. A. and Kopan, R (1998). Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393, 382-386.[Medline]
Seugnet, L., Simpson, P. and Haenlin, M (1997). Requirement for dynaminduring Notch signalling in Drosophila neurogenesis. Dev. Biol 192, 585-598.[Medline]
Shellenbarger, D. L. and Mohler, J. D (1978). Temperature sensitive periods and autonomy of pleiotropic effects of l(1)Ntsl , a conditional Notch lethal in Drosophila. Dev. Biol 62, 432-446.[Medline]
Sotillos, S., Roch, F. and Campuzano, S (1997). The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs. Development 124, 4769-4779.[Abstract]
Staehling-Hampton, K., Jackson, P. D., Clark, M. J., Brand, A. H. and Hoffmann, F. M (1994). Specificity of bone morphogenetic protein-related factors: cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A. Cell Growth Differ 5, 585-593.[Abstract]
Struhl, G. and Adachi, A (1998). Nuclear access and action of Notch in vivo. Cell 93, 649-660.[Medline]
Sun, X. and Artavanis-Tsakonas, S (1996). The intracellular deletions ofDELTA and SERRATE define dominant negative forms of the Drosophila Notch ligands. Development 122, 2465-2474.[Abstract]
Sun, X. and Artavanis-Tsakonas, S (1997). Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila. Development 124, 3439-3448.[Abstract]
V\212ssin, H., Bremer, K. A., Knust, E. and Campos-Ortega, J. A (1987). The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats. EMBO J 6, 3431-3440.[Medline]
Wen, C., Metzstein, M. M. and Greenwald, I (1997). Sup-17, a Caenorhabditis elegans ADAM protein related to Drosophila KUZBANIAN, and its role in LIN12/NOTCH signalling. Development 124, 4759-4767.[Abstract]
Woods, D. F. and Poodry, C. A (1983). Cell surface proteins of Drosophila. Dev. Biol 96, 23-31.[Medline]
Xue, Y., Gao, X., Lindsell, C. E., Norton, C. R., Chang, B., Hicks, C., Gendron-Maguire, M., Rand, E. B., Weinmaster, G. and Gridley, T (1999). Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum. Mol. Genet 8, 723-730.[Abstract/Free Full Text]
