Akagi, K., Sandig, V., Vooijs, M., Van der Valk, M., Giovannini, M., Strauss, M. and Berns, A (1997). Cre-mediated somatic site-specific recombination in mice. Nucleic Acids Res 25, 1766-1773.[Abstract/Free Full Text]
Baron, J., Klein, K. O., Yanovski, J. A., Novosad, J. A., Bacher, J. D., Bolander, M. E. and Cutler, G. B., Jr (1994). Induction of growth plate cartilage ossification by basic fibroblast growth factor. Endocrinology 135, 2790-2793.[Abstract]
Bi, W., Drake, C. J. and Schwarz, J. J (1999). The transcription factorMEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF. Dev. Biol 211, 255-267.[Medline]
Breier, G., Clauss, M. and Risau, W (1995). Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development. Dev. Dyn 204, 228-239.[Medline]
Caplan, A. I (1985). The vasculature and limb development. Cell Differ 16, 1-11.[Medline]
Carlevaro, M.F., Cermelli, S., Cancedda, R. and Cancedda, F.D (2000). Vascular endothelial growth factor (VEGF) in cartilage neovascularization and chondrocyte differentiation: auto-pracrine role during endochondral bone formation. J. Cell Sci 113, 59-69.[Abstract]
Carmeliet, P. and Collen, D (1999). Role of vascular endothelial growth factor and vascular endothelial growth factor receptors in vascular development. Curr. Top. Microbiol. Immunol 237, 133-158.[Medline]
Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Eberhardt, C., Declercq, C., Pawling, J., Moons, L., Collen, D., Risau, W. and Nagy,A (1996). Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380, 435-439.[Medline]
Carmeliet, P., Ng, Y. S., Nuyens, D., Theilmeier, G., Brusselmans, K., Cornelissen, I., Ehler, E., Kakkar, V. V., Stalmans, I., Mattot, V., Perriard, J. C., Dewerchin, M., Flameng, W., Nagy, A., Lupu, F., Moons, L., Collen, D., D'Amore, P. A. and Shima, D. T (1999). Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nat. Med 5, 495-502.[Medline]
Cheah, K. S., Lau, E. T., Au, P. K. and Tam, P. P (1991). Expression of the mouse alpha 1(II) collagen gene is not restricted to cartilage during development. Development 111, 945-953.[Abstract/Free Full Text]
Cheah, K. S., Levy, A., Trainor, P. A., Wai, A. W., Kuffner, T., So, C. L., Leung, K. K., Lovell-Badge, R. H. and Tam, P. P (1995). HumanCOL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development. J. Cell Biol 128, 223-237.[Abstract/Free Full Text]
Cleaver, O. and Krieg, P. A (1998). VEGF mediates angioblast migration during development of the dorsal aorta in Xenopus. Development 125, 3905-3914.[Abstract]
Descalzi Cancedda, F., Melchiori, A., Benelli, R., Gentili, C., Masiello, L., Campanile, G., Cancedda, R. and Albini, A (1995). Production of angiogenesis inhibitors and stimulators is modulated by cultured growth plate chondrocytes during in vitro differentiation: dependence on extracellular matrix assembly. Eur. J. Cell Biol 66, 60-68.[Medline]
Dumont, D. J., Fong, G. H., Puri, M. C., Gradwohl, G., Alitalo, K. and Breitman, M. L (1995). Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development. Dev. Dyn 203, 80-92.[Medline]
Elsasser, A. and Schaper, J (1995). Hibernating myocardium: adaptation or degeneration?. Basic Res. Cardiol 90, 47-48.[Medline]
Eriksson, U. and Alitalo, K (1999). Structure, expression and receptor-binding properties of novel vascular endothelial growth factors. Curr. Top. Microbiol. Immunol 237, 41-57.[Medline]
Ferrara, N (1999). Vascular endothelial growth factor: molecular and biological aspects. Curr. Top. Microbiol. Immunol 237, 1-30.[Medline]
Ferrara, N., Carver-Moore, K., Chen, H., Dowd, M., Lu, L., O'Shea, K. S., Powell-Braxton, L., Hillan, K. J. and Moore, M. W (1996). Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380, 439-442.[Medline]
Fong, G. H., Rossant, J., Gertsenstein, M. and Breitman, M. L (1995). Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376, 66-70.[Medline]
Fouquet, B., Weinstein, B. M., Serluca, F. C. and Fishman, M. C (1997). Vessel patterning in the embryo of the zebrafish: guidance by notochord. Dev. Biol 183, 37-48.[Medline]
Gassmann, M., Casagranda, F., Orioli, D., Simon, H., Lai, C., Klein, R. and Lemke, G (1995). Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 378, 390-394.[Medline]
Gerber, H. P., Hillan, K. J., Ryan, A. M., Kowalski, J., Keller, G. A., Rangell, L., Wright, B. D., Radtke, F., Aguet, M. and Ferrara, N (1999). VEGF is required for growth and survival in neonatal mice. Development 126, 1149-1159.[Abstract]
Gerber, H. P., McMurtrey, A., Kowalski, J., Yan, M., Keyt, B. A., Dixit, V. and Ferrara, N (1998). Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J. Biol. Chem 273, 30336-30343.[Abstract/Free Full Text]
Gerber, H. P., Vu, T. H., Ryan, A. M., Kowalski, J., Werb, Z. and Ferrara, N (1999). VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat. Med 5, 623-628.[Medline]
Horner, A., Bishop, N. J., Bord, S., Beeton, C., Kelsall, A. W., Coleman, N. and Compston, J. E (1999). Immunolocalisation of vascular endothelial growth factor (VEGF) in human neonatal growth plate cartilage. J. Anat 194, 519-524.
Kramer, R., Bucay, N., Kane, D. J., Martin, L. E., Tarpley, J. E. and Theill, L. E (1996). Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development. Proc. Natl Acad. Sci. USA 93, 4833-4838.[Abstract/Free Full Text]
Lee, K. F., Simon, H., Chen, H., Bates, B., Hung, M. C. and Hauser, C (1995). Requirement for neuregulin receptor erbB2 in neural and cardiac development [see comments]. Nature 378, 394-398.[Medline]
Liang, D., Xu, X., Chin, A. J., Balasubramaniyan, N. V., Teo, M. A., Lam, T. J., Weinberg, E. S. and Ge, R (1998). Cloning and characterization of vascular endothelial growth factor (VEGF) from zebrafish, Danio rerio. Biochim. Biophys. Acta 1397, 14-20.[Medline]
Lin, Q., Lu, J., Yanagisawa, H., Webb, R., Lyons, G. E., Richardson, J. A. and Olson, E. N (1998). Requirement of the MADS-box transcription factor MEF2C for vascular development. Development 125, 4565-4574.[Abstract]
Millauer, B., Wizigmann-Voos, S., Schnurch, H., Martinez, R., Moller, N. P., Risau, W. and Ullrich, A (1993). High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72, 835-846.[Medline]
Miquerol, L., Gertsenstein, M., Harpal, K., Rossant, J. and Nagy, A (1999). Multiple developmental roles of VEGF suggested by a LacZ-tagged allele. Dev. Biol 212, 307-322.[Medline]
Neufeld, G., Cohen, T., Gitay-Goren, H., Poltorak, Z., Tessler, S., Sharon, R., Gengrinovitch, S. and Levi, B. Z (1996). Similarities and differences between the vascular endothelial growth factor (VEGF) splice variants. Cancer Metastasis Rev 15, 153-158.[Medline]
Pfarr, D. S., Rieser, L. A., Woychik, R. P., Rottman, F. M., Rosenberg, M. and Reff, M. E (1986). Differential effects of polyadenylation regions on gene expression in mammalian cells. DNA 5, 115-122.[Medline]
Sato, T. N., Tozawa, Y., Deutsch, U., Wolburg-Buchholz, K., Fujiwara, Y., Gendron-Maguire, M., Gridley, T., Wolburg, H., Risau, W. and Qin, Y (1995). Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 376, 70-74.[Medline]
Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L. and Schuh, A. C (1995). Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376, 62-66.[Medline]
Sibilia, M. and Wagner, E. F (1995). Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269, 234-238.[Abstract/Free Full Text]
Suri, C., Jones, P. F., Patan, S., Bartunkova, S., Maisonpierre, P. C., Davis, S., Sato, T. N. and Yancopoulos, G. D (1996). Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 87, 1171-1180.[Medline]
Suzuki, F (1996). Roles of cartilage matrix proteins, chondromodulin-I and-II, in endochondral bone formation: a review. Connect. Tissue Res 35, 303-307.[Medline]
Towbin, J. A (1998). The role of cytoskeletal proteins in cardiomyopathies. Curr. Opin. Cell Biol 10, 131-139.[Medline]
Towbin, J. A., Bowles, K. R. and Bowles, N. E (1999). Etiologies of cardiomyopathy and heart failure. Nat. Med 5, 266-267.[Medline]
Vanoverschelde, J. L., Wijns, W., Borgers, M., Heyndrickx, G., Depre, C., Flameng, W. and Melin, J. A (1997). Chronic myocardial hibernation in humans. From bedside to bench. Circulation 95, 1961-1971.[Free Full Text]
Vu, T. H., Shipley, J. M., Bergers, G., Berger, J. E., Helms, J. A., Hanahan, D., Shapiro, S. D., Senior, R. M. and Werb, Z (1998). MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 93, 411-422.[Medline]