Early mouse endoderm is patterned by soluble factors from adjacent germ layers

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Wells, J. M.
	Articles by Melton, D. A.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Wells, J. M.
	Articles by Melton, D. A.

Ahlgren, U., Pfaff, S. L., Jessell, T. M., Edlund, T. and Edlund, H (1997). Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. Nature 385, 257-260.[Medline]

Ang, S. L., Conlon, R. A., Jin, O. and Rossant, J (1994). Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants. Development 120, 2979-2989.[Abstract]

Ang, S. L. and Rossant, J (1993). Anterior mesendoderm induces mouse Engrailed genes in explant cultures. Development 118, 139-149.[Abstract]

Ang, S. L. and Rossant, J (1994). HNF-3 beta is essential for node and notochord formation in mouse development. Cell 78, 561-574.[Medline]

Beck, F., Erler, T., Russell, A. and James, R (1995). Expression of Cdx-2 in the mouse embryo and placenta: possible role in patterning of the extra-embryonic membranes. Dev. Dyn 204, 219-227.[Medline]

Beddington, R. S. and Smith, J. C (1993). Control of vertebrate gastrulation: inducing signals and responding genes. Curr. Opin. Genet. Dev 3, 655-661.[Medline]

Biben, C., Stanley, E., Fabri, L., Kotecha, S., Rhinn, M., Drinkwater, C., Lah, M., Wang, C. C., Nash, A., Hilton, D. et al (1998). Murine cerberus homologue mCer-1: a candidate anterior patterning molecule. Dev. Biol 194, 135-151.[Medline]

Bouwmeester, T., Kim, S., Sasai, Y., Lu, B. and De Robertis, E. M (1996). Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer. Nature 382, 595-601.[Medline]

Burdsal, C. A., Flannery, M. L. and Pedersen, R. A (1998). FGF-2 alters the fate of mouse epiblast from ectoderm to mesoderm in vitro. Dev. Biol 198, 231-244.[Medline]

Ciruna, B. G., Schwartz, L., Kendraprasad, H., Yamaguchi, T. and Rossant, J (1997). Chimeric analysis of fibroblast growth factor receptor (FgFR1) function: a role for FGFR1 in morphogenetic movement through the primitive streak. Development 124, 2829-2841.[Abstract]

Conlon, F. L., Lyons, K. M., Takaesu, N., Barth, K. S., Kispert, A., Herrmann, B. and Robertson, E. J (1994). A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development 120, 1919-1928.[Abstract]

Cox, W. G. and Hemmati-Brivanlou, A (1995). Caudalization of neural fate by tissue recombination and bFGF. Development 121, 4349-4358.[Abstract]

Deng, C. X., Wynshaw-Boris, A., Shen, M. M., Daugherty, C., Ornitz, D. M. and Leder, P (1994). Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev 8, 3045-3057.[Abstract/Free Full Text]

Dickinson, M. E., Selleck, M. A., McMahon, A. P. and Bronner-Fraser, M (1995). Dorsalization of the neural tube by the non-neural ectoderm. Development 121, 2099-2106.[Abstract]

Downs, K. M. and Davies, T (1993). Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope. Development 118, 1255-1266.[Abstract]

Feldman, B., Poueymirou, W., Papaioannou, V. E., DeChiara, T. M. and Goldfarb, M (1995). Requirement of FGF-4 for postimplantation mouse development. Science 267, 246-249.[Abstract/Free Full Text]

Gittes, G. K. and Rutter, W. J (1992). Onset of cell-specific gene expression in the developing mouse pancreas. Proc. Natl. Acad. Sci. USA 89, 1128-1132.[Abstract/Free Full Text]

Goudet, G., Delhalle, S., Biemar, F., Martial, J. A. and Peers, B (1999). Functional and cooperative interactions between the homeodomain PDX1, Pbx, and Prep1 factors on the somatostatin promoter. J. Biol. Chem 274, 4067-4073.[Abstract/Free Full Text]

Green, R. P., Cohn, S. M., Sacchettini, J. C., Jackson, K. E. and Gordon, J. I (1992). The mouse intestinal fatty acid binding protein gene: nucleotide sequence, pattern of developmental and regional expression, and proposed structure of its protein product. DNA Cell Biol 11, 31-41.[Medline]

Gualdi, R., Bossard, P., Zheng, M., Hamada, Y., Coleman, J. R. and Zaret, K. S (1996). Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control. Genes Dev 10, 1670-1682.[Abstract/Free Full Text]

Hamburger and Hamilton (1951). A series of normal stages in the development of chick embryos. J. Morphol 88, 49-92.

Hebert, J. M., Basilico, C., Goldfarb, M., Haub, O. and Martin, G. R (1990). Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. Dev. Biol 138, 454-463.[Medline]

Hebrok, M., Kim, S. K. and Melton, D. A (1998). Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes Dev 12, 1705-1713.[Abstract/Free Full Text]

Henry, G. L. and Melton, D. A (1998). Mixer, a homeobox gene required for endoderm development. Science 281, 91-96.[Abstract/Free Full Text]

Hudson, C., Clements, D., Friday, R. V., Stott, D. and Woodland, H. R (1997). Xsox17alpha and-beta mediate endoderm formation in Xenopus. Cell 91, 397-405.[Medline]

Jonsson, J., Carlsson, L., Edlund, T. and Edlund, H (1994). Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371, 606-609.[Medline]

Jung, J., Zheng, M., Goldfarb, M. and Zaret, K. S (1999). Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science 284, 1998-2003.[Abstract/Free Full Text]

Keynes, R., Tannahill, D., Morgenstern, D. A., Johnson, A. R., Cook, G. M. and Pini, A (1997). Surround repulsion of spinal sensory axons in higher vertebrate embryos. Neuron 18, 889-897.[Medline]

Kim, S. K., Hebrok, M. and Melton, D. A (1997). Notochord to endoderm signaling is required for pancreas development. Development 124, 4243-4252.[Abstract]

Krapp, A., Knofler, M., Ledermann, B., K, B. r., Berney, C., Zoerkler, N., Hagenb chle, O. and Wellauer, P. K (1998). The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas [In Process Citation]. Genes Dev 12, 3752-3763.[Abstract/Free Full Text]

Lawson, K. A., Meneses, J. J. and Pedersen, R. A (1986). Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer. Dev. Biol 115, 325-339.[Medline]

Lawson, K. A., Meneses, J. J. and Pedersen, R. A (1991). Clonal analysis of epiblast fate during germ layer formation in the mouse embryo. Development 113, 891-911.[Abstract]

Mansouri, A., Chowdhury, K. and Gruss, P (1998). Follicular cells of the thyroid gland require Pax8 gene function. Nature Genet 19, 87-90.[Medline]

Miralles, F., Czernichow, P. and Scharfmann, R (1998). Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development. Development 125, 1017-1024.[Abstract]

Moos, M., Tacke, R., Scherer, H., Teplow, D., Fruh, K. and Schachner, M (1988). Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin. Nature 334, 701-703.[Medline]

Narita, N., Bielinska, M. and Wilson, D. B (1997). Wild-type endoderm abrogates the ventral developmental defects associated with GATA-4 deficiency in the mouse. Dev. Biol 189, 270-274.[Medline]

Naya, F. J., Huang, H. P., Qiu, Y., Mutoh, H., DeMayo, F. J., Leiter, A. B. and Tsai, M. J (1997). Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev 11, 2323-2334.[Abstract/Free Full Text]

Niswander, L. and Martin, G. R (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.[Abstract]

Ohlsson, H., Karlsson, K. and Edlund, T (1993). IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12, 4251-4259.[Medline]

Ornitz, D. M., Xu, J., Colvin, J. S., McEwen, D. G., MacArthur, C. A., Coulier, F., Gao, G. and Goldfarb, M (1996). Receptor specificity of the fibroblast growth factor family. J. Biol. Chem 271, 15292-15297.[Abstract/Free Full Text]

Peters, H., Neubuser, A., Kratochwil, K. and Balling, R (1998). Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev 12, 2735-2747.[Abstract/Free Full Text]

Rhinn, M., Dierich, A., Shawlot, W., Behringer, R. R., Le Meur, M. and Ang, S. L (1998). Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification. Development 125, 845-856.[Abstract]

Roberts, D. J., Smith, D. M., Goff, D. J. and Tabin, C. J (1998). Epithelial-mesenchymal signaling during the regionalization of the chick gut. Development 125, 2791-2801.[Abstract]

Schultheiss, T. M., Xydas, S. and Lassar, A. B (1995). Induction of aviancardiac myogenesis by anterior endoderm. Development 121, 4203-4214.[Abstract]

Sokol, S. and Melton, D. A (1991). Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin. Nature 351, 409-411.[Medline]

Sosa-Pineda, B., Chowdhury, K., Torres, M., Oliver, G. and Gruss, P (1997). The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature 386, 399-402.[Medline]

St-Onge, L., Sosa-Pineda, B., Chowdhury, K., Mansouri, A. and Gruss, P (1997). Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas. Nature 387, 406-409.[Medline]

Sussel, L., Kalamaras, J., Hartigan-O'Connor, D. J., Meneses, J. J., Pedersen, R. A., Rubenstein, J. L. and German, M. S (1998). Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 125, 2213-2221.[Abstract]

Thomas, P. and Beddington, R (1996). Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo. Curr. Biol 6, 1487-1496.[Medline]

Varlet, I., Collignon, J. and Robertson, E. J (1997). nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development 124, 1033-1044.[Abstract]

Wells, J. M. and Melton, D. A (1999). Vertebrate endoderm development. Annu. Rev. Cell Dev. Biol 15, 393-410.[Medline]

Wilson, P. A. and Melton, D. A (1994). Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication. Curr. Biol 4, 676-686.[Medline]

Yamaguchi, T. P., Harpal, K., Henkemeyer, M. and Rossant, J (1994). fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev 8, 3032-3044.[Abstract/Free Full Text]

Yamaguchi, T. P. and Rossant, J (1995). Fibroblast growth factors in mammalian development. Curr. Opin. Genet. Dev 5, 485-491.[Medline]

Zambrowicz, B. P., Imamoto, A., Fiering, S., Herzenberg, L. A., Kerr, W. G. and Soriano, P (1997). Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc. Natl. Acad. Sci. USA 94, 3789-3794.[Abstract/Free Full Text]

This article has been cited by other articles:

S. Agarwal, K. L. Holton, and R. Lanza
Efficient Differentiation of Functional Hepatocytes from Human Embryonic Stem Cells
Stem Cells, May 1, 2008; 26(5): 1117 - 1127.
[Abstract] [Full Text] [PDF]

N. Shiraki, T. Yoshida, K. Araki, A. Umezawa, Y. Higuchi, H. Goto, K. Kume, and S. Kume
Guided Differentiation of Embryonic Stem Cells into Pdx1-Expressing Regional-Specific Definitive Endoderm
Stem Cells, April 1, 2008; 26(4): 874 - 885.
[Abstract] [Full Text] [PDF]

C. H. Cho, N. Parashurama, E. Y. H. Park, K. Suganuma, Y. Nahmias, J. Park, A. W. Tilles, F. Berthiaume, and M. L. Yarmush
Homogeneous differentiation of hepatocyte-like cells from embryonic stem cells: applications for the treatment of liver failure
FASEB J, March 1, 2008; 22(3): 898 - 909.
[Abstract] [Full Text] [PDF]

F. M. Spagnoli and A. H. Brivanlou
The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm
Development, February 1, 2008; 135(3): 451 - 461.
[Abstract] [Full Text] [PDF]

N. Parashurama, Y. Nahmias, C. H. Cho, D. van Poll, A. W. Tilles, F. Berthiaume, and M. L. Yarmush
Activin Alters the Kinetics of Endoderm Induction in Embryonic Stem Cells Cultured on Collagen Gels
Stem Cells, February 1, 2008; 26(2): 474 - 484.
[Abstract] [Full Text] [PDF]

M. C. Jorgensen, J. Ahnfelt-Ronne, J. Hald, O. D. Madsen, P. Serup, and J. Hecksher-Sorensen
An Illustrated Review of Early Pancreas Development in the Mouse
Endocr. Rev., October 1, 2007; 28(6): 685 - 705.
[Abstract] [Full Text] [PDF]

G. R. van den Brink
Hedgehog Signaling in Development and Homeostasis of the Gastrointestinal Tract
Physiol Rev, October 1, 2007; 87(4): 1343 - 1375.
[Abstract] [Full Text] [PDF]

V. A. McLin, S. A. Rankin, and A. M. Zorn
Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas development
Development, June 15, 2007; 134(12): 2207 - 2217.
[Abstract] [Full Text] [PDF]

I. Aurich, L. P Mueller, H. Aurich, J. Luetzkendorf, K. Tisljar, M. M Dollinger, W. Schormann, J. Walldorf, J. G Hengstler, W. E Fleig, et al.
Functional integration of hepatocytes derived from human mesenchymal stem cells into mouse livers
Gut, March 1, 2007; 56(3): 405 - 415.
[Abstract] [Full Text] [PDF]

L. C. Murtaugh
Pancreas and beta-cell development: from the actual to the possible
Development, February 1, 2007; 134(3): 427 - 438.
[Abstract] [Full Text] [PDF]

A. B. McLean, K. A. D'Amour, K. L. Jones, M. Krishnamoorthy, M. J. Kulik, D. M. Reynolds, A. M. Sheppard, H. Liu, Y. Xu, E. E. Baetge, et al.
Activin A Efficiently Specifies Definitive Endoderm from Human Embryonic Stem Cells Only When Phosphatidylinositol 3-Kinase Signaling Is Suppressed
Stem Cells, January 1, 2007; 25(1): 29 - 38.
[Abstract] [Full Text] [PDF]

C.-C. Chien, B. L. Yen, F.-K. Lee, T.-H. Lai, Y.-C. Chen, S.-H. Chan, and H.-I Huang
In Vitro Differentiation of Human Placenta-Derived Multipotent Cells into Hepatocyte-Like Cells
Stem Cells, July 1, 2006; 24(7): 1759 - 1768.
[Abstract] [Full Text] [PDF]

W. V. Cardoso and J. Lu
Regulation of early lung morphogenesis: questions, facts and controversies
Development, May 1, 2006; 133(9): 1611 - 1624.
[Abstract] [Full Text] [PDF]

D. Stafford, R. J. White, M. D. Kinkel, A. Linville, T. F. Schilling, and V. E. Prince
Retinoids signal directly to zebrafish endoderm to specify insulin-expressing {beta}-cells
Development, March 1, 2006; 133(5): 949 - 956.
[Abstract] [Full Text] [PDF]

R. T. Bottcher and C. Niehrs
Fibroblast Growth Factor Signaling during Early Vertebrate Development
Endocr. Rev., February 1, 2005; 26(1): 63 - 77.
[Abstract] [Full Text] [PDF]

A. E. Serls, S. Doherty, P. Parvatiyar, J. M. Wells, and G. H. Deutsch
Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung
Development, January 1, 2005; 132(1): 35 - 47.
[Abstract] [Full Text] [PDF]

H. T. Ku, N. Zhang, A. Kubo, R. O'Connor, M. Mao, G. Keller, and J. S. Bromberg
Committing Embryonic Stem Cells to Early Endocrine Pancreas In Vitro
Stem Cells, December 1, 2004; 22(7): 1205 - 1217.
[Abstract] [Full Text] [PDF]

T. Niimi, Y. Hayashi, S. Futaki, and K. Sekiguchi
SOX7 and SOX17 Regulate the Parietal Endoderm-specific Enhancer Activity of Mouse Laminin {alpha}1 Gene
J. Biol. Chem., September 3, 2004; 279(36): 38055 - 38061.
[Abstract] [Full Text] [PDF]

R. Bort, J. P. Martinez-Barbera, R. S. P. Beddington, and K. S. Zaret
Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas
Development, February 15, 2004; 131(4): 797 - 806.
[Abstract] [Full Text] [PDF]

L. Vallier, P. J. Rugg-Gunn, I. A. Bouhon, F. K. Andersson, A. J. Sadler, and R. A. Pedersen
Enhancing and Diminishing Gene Function in Human Embryonic Stem Cells
Stem Cells, January 1, 2004; 22(1): 2 - 11.
[Abstract] [Full Text] [PDF]

G. Gu, J. M. Wells, D. Dombkowski, F. Preffer, B. Aronow, and D. A. Melton
Global expression analysis of gene regulatory pathways during endocrine pancreatic development
Development, January 1, 2004; 131(1): 165 - 179.
[Abstract] [Full Text] [PDF]

L. Rachdi, J.-C. Marie, and R. Scharfmann
Role for VPAC2 Receptor-Mediated Signals in Pancreas Development
Diabetes, January 1, 2003; 52(1): 85 - 92.
[Abstract] [Full Text] [PDF]

G. M. Beattie, A. M.P. Montgomery, A. D. Lopez, E. Hao, B. Perez, M. L. Just, J. R.T. Lakey, M. E. Hart, and A. Hayek
A Novel Approach to Increase Human Islet Cell Mass While Preserving {beta}-Cell Function
Diabetes, December 1, 2002; 51(12): 3435 - 3439.
[Abstract] [Full Text] [PDF]

A.-K. T. Perl, S. E. Wert, A. Nagy, C. G. Lobe, and J. A. Whitsett
Early restriction of peripheral and proximal cell lineages during formation of the lung
PNAS, August 6, 2002; 99(16): 10482 - 10487.
[Abstract] [Full Text] [PDF]

C. S. Lee, N. J. Sund, M. Z. Vatamaniuk, F. M. Matschinsky, D. A. Stoffers, and K. H. Kaestner
Foxa2 Controls Pdx1 Gene Expression in Pancreatic {beta}-Cells In Vivo
Diabetes, August 1, 2002; 51(8): 2546 - 2551.
[Abstract] [Full Text] [PDF]

L. A. Barlow
Specification of pharyngeal endoderm is dependent on early signals from axial mesoderm
Development, November 15, 2001; 128(22): 4573 - 4583.
[Abstract] [Full Text] [PDF]

N. B. David and F. M. Rosa
Cell autonomous commitment to an endodermal fate and behaviour by activation of Nodal signalling
Development, October 15, 2001; 128(20): 3937 - 3947.
[Abstract] [Full Text] [PDF]

P. A. Hoodless, M. Pye, C. Chazaud, E. Labbé, L. Attisano, J. Rossant, and J. L. Wrana
FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse
Genes & Dev., May 15, 2001; 15(10): 1257 - 1271.
[Abstract] [Full Text]

S. K. Kim and M. Hebrok
Intercellular signals regulating pancreas development and function
Genes & Dev., January 15, 2001; 15(2): 111 - 127.
[Full Text]

G Deutsch, J Jung, M Zheng, J Lora, and K. Zaret
A bipotential precursor population for pancreas and liver within the embryonic endoderm
Development, January 3, 2001; 128(6): 871 - 881.
[Abstract] [PDF]

P Bossard and K. Zaret
Repressive and restrictive mesodermal interactions with gut endoderm: possible relation to Meckel's Diverticulum
Development, January 11, 2000; 127(22): 4915 - 4923.
[Abstract] [PDF]

E. Lammert, O. Cleaver, and D. Melton
Induction of Pancreatic Differentiation by Signals from Blood Vessels
Science, October 19, 2001; 294(5542): 564 - 567.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Wells, J. M.

Articles by Melton, D. A.

Search for Related Content

PubMed

PubMed Citation

Articles by Wells, J. M.

Articles by Melton, D. A.

				N. Shiraki, T. Yoshida, K. Araki, A. Umezawa, Y. Higuchi, H. Goto, K. Kume, and S. Kume Guided Differentiation of Embryonic Stem Cells into Pdx1-Expressing Regional-Specific Definitive Endoderm Stem Cells, April 1, 2008; 26(4): 874 - 885. [Abstract] [Full Text] [PDF]

				C. H. Cho, N. Parashurama, E. Y. H. Park, K. Suganuma, Y. Nahmias, J. Park, A. W. Tilles, F. Berthiaume, and M. L. Yarmush Homogeneous differentiation of hepatocyte-like cells from embryonic stem cells: applications for the treatment of liver failure FASEB J, March 1, 2008; 22(3): 898 - 909. [Abstract] [Full Text] [PDF]

				F. M. Spagnoli and A. H. Brivanlou The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm Development, February 1, 2008; 135(3): 451 - 461. [Abstract] [Full Text] [PDF]

				N. Parashurama, Y. Nahmias, C. H. Cho, D. van Poll, A. W. Tilles, F. Berthiaume, and M. L. Yarmush Activin Alters the Kinetics of Endoderm Induction in Embryonic Stem Cells Cultured on Collagen Gels Stem Cells, February 1, 2008; 26(2): 474 - 484. [Abstract] [Full Text] [PDF]

				M. C. Jorgensen, J. Ahnfelt-Ronne, J. Hald, O. D. Madsen, P. Serup, and J. Hecksher-Sorensen An Illustrated Review of Early Pancreas Development in the Mouse Endocr. Rev., October 1, 2007; 28(6): 685 - 705. [Abstract] [Full Text] [PDF]

				G. R. van den Brink Hedgehog Signaling in Development and Homeostasis of the Gastrointestinal Tract Physiol Rev, October 1, 2007; 87(4): 1343 - 1375. [Abstract] [Full Text] [PDF]

				V. A. McLin, S. A. Rankin, and A. M. Zorn Repression of Wnt/{beta}-catenin signaling in the anterior endoderm is essential for liver and pancreas development Development, June 15, 2007; 134(12): 2207 - 2217. [Abstract] [Full Text] [PDF]

				I. Aurich, L. P Mueller, H. Aurich, J. Luetzkendorf, K. Tisljar, M. M Dollinger, W. Schormann, J. Walldorf, J. G Hengstler, W. E Fleig, et al. Functional integration of hepatocytes derived from human mesenchymal stem cells into mouse livers Gut, March 1, 2007; 56(3): 405 - 415. [Abstract] [Full Text] [PDF]

				L. C. Murtaugh Pancreas and beta-cell development: from the actual to the possible Development, February 1, 2007; 134(3): 427 - 438. [Abstract] [Full Text] [PDF]

				A. B. McLean, K. A. D'Amour, K. L. Jones, M. Krishnamoorthy, M. J. Kulik, D. M. Reynolds, A. M. Sheppard, H. Liu, Y. Xu, E. E. Baetge, et al. Activin A Efficiently Specifies Definitive Endoderm from Human Embryonic Stem Cells Only When Phosphatidylinositol 3-Kinase Signaling Is Suppressed Stem Cells, January 1, 2007; 25(1): 29 - 38. [Abstract] [Full Text] [PDF]

				C.-C. Chien, B. L. Yen, F.-K. Lee, T.-H. Lai, Y.-C. Chen, S.-H. Chan, and H.-I Huang In Vitro Differentiation of Human Placenta-Derived Multipotent Cells into Hepatocyte-Like Cells Stem Cells, July 1, 2006; 24(7): 1759 - 1768. [Abstract] [Full Text] [PDF]

				W. V. Cardoso and J. Lu Regulation of early lung morphogenesis: questions, facts and controversies Development, May 1, 2006; 133(9): 1611 - 1624. [Abstract] [Full Text] [PDF]

				D. Stafford, R. J. White, M. D. Kinkel, A. Linville, T. F. Schilling, and V. E. Prince Retinoids signal directly to zebrafish endoderm to specify insulin-expressing {beta}-cells Development, March 1, 2006; 133(5): 949 - 956. [Abstract] [Full Text] [PDF]

				R. T. Bottcher and C. Niehrs Fibroblast Growth Factor Signaling during Early Vertebrate Development Endocr. Rev., February 1, 2005; 26(1): 63 - 77. [Abstract] [Full Text] [PDF]

				A. E. Serls, S. Doherty, P. Parvatiyar, J. M. Wells, and G. H. Deutsch Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung Development, January 1, 2005; 132(1): 35 - 47. [Abstract] [Full Text] [PDF]

				H. T. Ku, N. Zhang, A. Kubo, R. O'Connor, M. Mao, G. Keller, and J. S. Bromberg Committing Embryonic Stem Cells to Early Endocrine Pancreas In Vitro Stem Cells, December 1, 2004; 22(7): 1205 - 1217. [Abstract] [Full Text] [PDF]

				T. Niimi, Y. Hayashi, S. Futaki, and K. Sekiguchi SOX7 and SOX17 Regulate the Parietal Endoderm-specific Enhancer Activity of Mouse Laminin {alpha}1 Gene J. Biol. Chem., September 3, 2004; 279(36): 38055 - 38061. [Abstract] [Full Text] [PDF]

				R. Bort, J. P. Martinez-Barbera, R. S. P. Beddington, and K. S. Zaret Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas Development, February 15, 2004; 131(4): 797 - 806. [Abstract] [Full Text] [PDF]

				L. Vallier, P. J. Rugg-Gunn, I. A. Bouhon, F. K. Andersson, A. J. Sadler, and R. A. Pedersen Enhancing and Diminishing Gene Function in Human Embryonic Stem Cells Stem Cells, January 1, 2004; 22(1): 2 - 11. [Abstract] [Full Text] [PDF]

				G. Gu, J. M. Wells, D. Dombkowski, F. Preffer, B. Aronow, and D. A. Melton Global expression analysis of gene regulatory pathways during endocrine pancreatic development Development, January 1, 2004; 131(1): 165 - 179. [Abstract] [Full Text] [PDF]

				L. Rachdi, J.-C. Marie, and R. Scharfmann Role for VPAC2 Receptor-Mediated Signals in Pancreas Development Diabetes, January 1, 2003; 52(1): 85 - 92. [Abstract] [Full Text] [PDF]

				G. M. Beattie, A. M.P. Montgomery, A. D. Lopez, E. Hao, B. Perez, M. L. Just, J. R.T. Lakey, M. E. Hart, and A. Hayek A Novel Approach to Increase Human Islet Cell Mass While Preserving {beta}-Cell Function Diabetes, December 1, 2002; 51(12): 3435 - 3439. [Abstract] [Full Text] [PDF]

				A.-K. T. Perl, S. E. Wert, A. Nagy, C. G. Lobe, and J. A. Whitsett Early restriction of peripheral and proximal cell lineages during formation of the lung PNAS, August 6, 2002; 99(16): 10482 - 10487. [Abstract] [Full Text] [PDF]

				C. S. Lee, N. J. Sund, M. Z. Vatamaniuk, F. M. Matschinsky, D. A. Stoffers, and K. H. Kaestner Foxa2 Controls Pdx1 Gene Expression in Pancreatic {beta}-Cells In Vivo Diabetes, August 1, 2002; 51(8): 2546 - 2551. [Abstract] [Full Text] [PDF]

				L. A. Barlow Specification of pharyngeal endoderm is dependent on early signals from axial mesoderm Development, November 15, 2001; 128(22): 4573 - 4583. [Abstract] [Full Text] [PDF]

				N. B. David and F. M. Rosa Cell autonomous commitment to an endodermal fate and behaviour by activation of Nodal signalling Development, October 15, 2001; 128(20): 3937 - 3947. [Abstract] [Full Text] [PDF]

				P. A. Hoodless, M. Pye, C. Chazaud, E. Labbé, L. Attisano, J. Rossant, and J. L. Wrana FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse Genes & Dev., May 15, 2001; 15(10): 1257 - 1271. [Abstract] [Full Text]

				S. K. Kim and M. Hebrok Intercellular signals regulating pancreas development and function Genes & Dev., January 15, 2001; 15(2): 111 - 127. [Full Text]

				G Deutsch, J Jung, M Zheng, J Lora, and K. Zaret A bipotential precursor population for pancreas and liver within the embryonic endoderm Development, January 3, 2001; 128(6): 871 - 881. [Abstract] [PDF]

				P Bossard and K. Zaret Repressive and restrictive mesodermal interactions with gut endoderm: possible relation to Meckel's Diverticulum Development, January 11, 2000; 127(22): 4915 - 4923. [Abstract] [PDF]