Arceci, R. J., King, A. A., Simon, M. C., Orkin, S. H. and Wilson, D. B (1993). Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart. Mol. Cell Biol 13, 2235-2246.[Abstract/Free Full Text]
Begley, C. G., Aplan, P. D., Denning, S. M., Haynes, B. F., Waldmann T. A. and Kirsch, I. R (1989). The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif. Proc. Natl. Acad. Sci. USA 86, 10128-10132.[Abstract/Free Full Text]
Chelly, J., Kaplan, J. C., Maire, P., Gautron, S. and Kahn, A (1988). Transcription of the dystrophin gene in human muscle and non-muscle tissue. Nature 333, 858-860.[Medline]
Choi, K., Kennedy, M., Kazarov, A., Papadimitriou, J. C. and Keller, G (1998). A common precursor for hematopoietic and endothelial cells. Development 125, 725-732.[Abstract]
Chomczynski, P. and Sacchi, N (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analyt. Biochem 162, 156-159.[Medline]
Cornell, R. A. and Kimelman, D (1994). Activin-mediated mesoderm induction requires FGF. Development 120, 453-462.[Abstract]
Deng, C. X., Wynshaw-Boris, A., Shen, M. M., Daugherty, C., Ornitz, D. M. and Leder, P (1994). Murine FGFR1 is required for early postimplantation growth and axial organization. Genes Dev 8, 3045-3057.[Abstract/Free Full Text]
Dumont, D. J., Fong, G. H., Puri, M. C., Gradwohl, G., Alitalo, K. and Breitman, M. L (1995). Vascularization of the mouse embryo: a study of Flk1, tek, tie, and vascular endothelial growth factor expression during development. Dev. Dyn 203, 80-92.[Medline]
Elefanty, A. G., Robb, L. Birner, R. and Begley, C. G (1997). Hematopoietic-specific genes are not induced during in vitro differentiation of scl-null embryonic stem cells. Blood 90, 1435-1447.[Abstract/Free Full Text]
Gering, M., Rodaway, A. R. F., Gottgens, B., Patient R. K. and Green, A. R (1998). The SCL gene specifies haemangioblast development from early mesoderm. EMBO J 17, 4029-4045.[Medline]
Huber, T. L., Zhou, Y., Mead, P. E. and Zon, L. I (1998). Cooperative effects of growth factors involved in the induction of hematopoietic mesoderm. Blood 92, 4128-4137.[Abstract/Free Full Text]
Jaffredo, T., Gautier, R., Eichmann, A. and Dieterlen-Lievre, F (1998). Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny. Development 125, 4575-4583.[Abstract]
Johansson, B. M. and Wiles, M. V (1995). Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development. Mol. Cell Biol 15, 141-151.[Abstract]
Kabrun, N., Buhring, H. J., Choi, K., Ullrich, A., Risau, W. and Keller, G (1997). Flk1 expression defines a population of early embryonic hematopoietic precursors. Development 124, 2039-2048.[Abstract]
Kallianpur, A. R., Jordan, J. E. and Brandt,S. J (1994). The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood 83, 1200-1208.[Abstract/Free Full Text]
Karasuyama, H. and Melchers, F (1988). Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol 18, 97-104.[Medline]
Keller, G., Kennedy, M., Papayannopoulou, T. and Wiles, M. V (1993). Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol. Cell Biol 13, 473-486.[Abstract/Free Full Text]
Keller, G. M (1995). In vitro differentiation of embryonic stem cells. Curr. Opin. Cell Biol 7, 862-869.[Medline]
Kennedy, M., Firpo, M., Choi, K., Wall, C., Robertson, S., Kabrun, N. and Keller, G (1997). A common precursor for primitive erythropoiesis and definitive haematopoiesis. Nature 386, 488-493.[Medline]
LaBonne, C. and Whitman, M (1994). Mesoderm induction by activin requires FGF-mediated intracellular signals. Development 120, 463-472.[Abstract]
Liao, E. C., Paw, B. H., Oates, A. C., Pratt, S. J., Postlethwait, J. H. andZon. L. I (1998). SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. Genes Dev 12, 621-626.[Abstract/Free Full Text]
Miquerol, L., Gertsenstein, M., Harpal, K., Rossant, J. and Nagy, A (1999). Multiple developmental roles of VEGF suggested by a LacZ-tagged allele. Dev. Biol 212, 307-322.[Medline]
Mishina, Y., Suzuki, A., Ueno, N. and Behringer, R. R (1995). Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis. Genes Dev 9, 3027-3037.[Abstract/Free Full Text]
Murray, P. D. F (1932). The development in vitro of the blood of the early chick embryo. Proc. Roy. Soc. Lond 11, 497-521.
Nishikawa, S. I., Nishikawa, S., Hirashima, M., Matsuyoshi, N. and Kodama, H (1998). Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development 125, 1747-1757.[Abstract]
Pardanaud, L. and Dieterlen-Lievre, F (1999). Manipulation of the angiopoietic/hemangiopoietic commitment in the avian embryo. Development 126, 617-627.[Abstract]
Porcher, C., Swat, W., Rockwell, K., Fujiwara, Y., Alt, F. W. and Orkin. S. H (1996). The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell 86, 47-57.[Medline]
Robb, L., Lyons, I., Li, R., Hartley, L., Kontgen, F., Harvey, R. P., Metcalf, D. and Begley, C. G (1995). Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene. Proc. Natl. Acad. Sci. USA 92, 7075-7079.[Abstract/Free Full Text]
Robb, L., Elwood, N. J., Elefanty, A. G., Kontgen, F., Li, R., Barnett, L. D. and Begley, C. G (1996). The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse. EMBO J 15, 4123-4129.[Medline]
Schuh, A. C., Faloon, P., Hu, Q. L., Bhimani, M. andChoi, K (1999). In vitro hematopoietic and endothelial potential of Flk1 /embryonic stem cells and embryos. Proc. Natl. Acad. Sci.USA 96, 2159-2164.[Abstract/Free Full Text]
Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L. and Schuh, A. C (1995). Failure of blood-island formation and vasculogenesis in Flk1-deficient mice. Nature 376, 62-66.[Medline]
Shalaby, F., Ho. J., Stanford, W. L., Fischer, K.-D., Schuh, A., Schwartz, L., Bernstein, A. and Rossant, J (1997). A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89, 981-990.[Medline]
Shivdasani, R. A., Mayer, E. L. and Orkin, S. H (1995). Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Nature 373, 432-434.[Medline]
Silver, L. and Palis, J (1997). Initiation of murine embryonic erythropoiesis: a spatial analysis. Blood 89, 1154-1164.[Abstract/Free Full Text]
Stainier, D. Y., Weinstein, B. M., Detrich, 3rd, H. W., Zon, L. I. and Fishman, M. C (1995). Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. Development 121, 3141-3150.[Abstract]
Unkeless, J. C (1979). Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. J. Exp. Med 150, 580-596.[Abstract/Free Full Text]
Winnier, G., Blessing, M., Labosky, P. A. and Hogan, B. L (1995). Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev 9, 2105-2116.[Abstract/Free Full Text]
Yamada, G., Kioussi, C., Schubert, F. R., Eto, Y., Chowdhury, K., Pituello, F. and Gruss. P (1994). Regulated expression of Brachyury (T), Nkx1.1 and Pax genes in embryoid bodies. Biochem. Biophys. Res. Commun 199, 552-563.[Medline]
Yamaguchi, T. P., Dumont, D. J., Conlon, R. A., Breitman, M. L. and Rossant, J (1993). Flk1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development 118, 489-498.[Abstract]
Yamaguchi, T. P., Harpal, K. Henkemeyer, M. and Rossant, J (1994). fgfr1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev 8, 3032-3044.[Abstract/Free Full Text]