Adams, J. M. and Cory, S (1998). The Bcl-2 protein family: arbiters of cell survival. Science 281, 1322-1326.[Abstract/Free Full Text]
Allsopp, T. E., Kiselev, S., Wyatt, S. and Davies, A. M (1995). Role of Bcl-2 expression in the BDNF survival response. Eur. J. Neurosci 7, 1266-1272.[Medline]
Allsopp, T. E., Wyatt, S., Paterson, H. F. and Davies, A. M (1993). The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73, 295-307.[Medline]
Bar-Peled, O., Knudson, M., Korsmeyer, S. J. and Rothstein, J. D (1999). Motor neuron degeneration is attenuated in bax-deficient neurons in vitro. J. Neurosci. Res 55, 542-556.[Medline]
Boise, L. H., Gonzalez, G. M., Postema, C. E., Ding, L., Lindsten, T., Turka, L. A., Mao, X., Nunez, G. and Thompson, C. B (1993). bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74, 597-608.[Medline]
Buchman, V. L. and Davies, A. M (1993). Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons. Development 118, 989-1001.[Abstract]
Chomczynski, P. and Sacchi, N (1987). Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem 162, 156-159.[Medline]
Davies, A. M (1986). The survival and growth of embryonic proprioceptive neurons is promoted by a factor present in skeletal muscle. Dev. Biol 115, 56-67.[Medline]
Davies, A. M., Bandtlow, C., Heumann, R., Korsching, S., Rohrer, H. and Thoenen, H (1987). Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor. Nature 326, 353-358.[Medline]
Davies, A. M., Horton, A., Burton, L. E., Schmelzer, C., Vandlen, R. and Rosenthal, A (1993). Neurotrophin-4/5 is a mammalian-specific survival factor for distinct populations of sensory neurons. J. Neurosci 13, 4961-4967.[Abstract]
Davies, A. M., Lee, K. F. and Jaenisch, R (1993). p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins. Neuron 11, 565-574.[Medline]
Davies, A. M. and Lumsden, A. G. S (1984). Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion. J. Comp. Neurol 223, 124-137.[Medline]
Deckwerth, T. L., Elliott, J. L., Knudson, C. M., Johnson E. M, J., Snider, W. D. and Korsmeyer, S. J (1996). BAX is required for neuronal death after trophic factor deprivation and during development. Neuron 17, 401-411.[Medline]
Ernfors, P., Lee, K. F. and Jaenisch, R (1994). Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368, 147-150.[Medline]
Farlie, P. G., Dringen, R., Rees, S. M., Kannourakis, G. and Bernard, O (1995). bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc. Natl. Acad. Sci. USA 92, 4397-4401.[Abstract/Free Full Text]
Garcia, I., Martinou, I., Tsujimoto, Y. and Martinou, J. C (1992). Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258, 302-304.[Abstract/Free Full Text]
Gibson, L., Holmgreen, S. P., Huang, D. C., Bernard, O., Copeland, N. G., Jenkins, N. A., Sutherland, G. R., Baker, E., Adams, J. M. and Cory, S (1996). bcl-w, a novel member of the bcl-2 family, promotes cell survival. Oncogene 13, 665-675.[Medline]
Gillardon, F., Zimmermann, M., Uhlmann, E., Krajewski, S., Reed, J. C. and Klimaschewski, L (1996). Antisense oligodeoxynucleotides to bax mRNA promote survival of rat sympathetic neurons in culture. J. Neurosci. Res 43, 726-734.[Medline]
Gonzalez-Garcia, M., Garcia, I., Ding, L., O'Shea, S., Boise, L. H., Thompson, C. B. and Nunez, G (1995). bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death. Proc. Natl. Acad. Sci. USA 92, 4304-4308.[Abstract/Free Full Text]
Gonzalez-Garcia, M., Perez-Ballestero, R., Ding, L., Duan, L., Boise, L. H., Thompson, C. B. and Nunez, G (1994). bcl-xL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development 120, 3033-3042.[Abstract]
Hamner, S., Skoglosa, Y. and Lindholm, D (1999). Differential expression of bcl-w and bcl-x messenger RNA in the developing and adult rat nervous system. Neuroscience 91, 673-684.[Medline]
Hu, Y., Benedict, M. A., Wu, D., Inohara, N. and Nunez, G (1998). Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc. Natl. Acad. Sci. USA 95, 4386-4391.[Abstract/Free Full Text]
Jones, K. R., Farinas, I., Backus, C. and Reichardt, L. F (1994). Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76, 989-999.[Medline]
Kharbanda, S., Pandey, P., Schofield, L., Israels, S., Roncinske, R., Yoshida, K., Bharti, A., Yuan, Z. M., Saxena, S., Weichselbaum, R., Nalin, C. and Kufe, D (1997). Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis. Proc. Natl. Acad. Sci. USA 94, 6939-6942.[Abstract/Free Full Text]
Kluck, R. M., Bossy-Wetzel, E., Green, D. R. and Newmeyer, D. D (1997). The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis [see comments]. Science 275, 1132-1136.[Abstract/Free Full Text]
Korsmeyer, S. J (1999). BCL-2 gene family and the regulation of programmed cell death. Cancer Res 59, 1693-1700.
Korsmeyer, S. J., Shutter, J. R., Veis, D. J., Merry, D. E. and Oltvai, Z. N (1993). Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death. Semin. Cancer Biol 4, 327-332.[Medline]
Krebs, J. F., Armstrong, R. C., Srinivasan, A., Aja, T., Wong, A. M., Aboy, A., Sayers, R., Pham, B., Vu, T., Hoang, K., Karanewsky, D. S., Leist, C., Schmitz, A., Wu, J. C., Tomaselli, K. J. and Fritz, L. C (1999). Activation of membrane-associated procaspase-3 is regulated by Bcl-2. J. Cell Biol 144, 915-926.[Abstract/Free Full Text]
Li, F., Srinivasan, A., Wang, Y., Armstrong, R. C., Tomaselli, K. J. and Fritz, L. C (1997). Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release. J. Biol. Chem 272, 30299-305.[Abstract/Free Full Text]
Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M.,Alnemri, E. S. and Wang, X (1997). Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-89.[Medline]
Martinou, I., Missotten, M., Fernandez, P. A., Sadoul, R. and Martinou, J. C (1998). Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons. Neuroreport 9, 15-19.[Medline]
Martinou, J. C., Dubois-Dauphin, M., Staple, J. K., Rodriguez, I., Frankowsky, H., Missotten, M., Albertini, P., Talabot, D., Catsicas, S., Pietra, C. and Huarte, J (1994). Overexpression of bcl-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischaemia. Neuron 13, 1017-1030.[Medline]
Merry, D. E., Veis, D. J., Hickey, W. F. and Korsmeyer, S. J (1994). bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development 120, 301-311.[Abstract]
Michaelidis, T. M., Sendtner, M., Cooper, J. D., Airaksinen, M. S., Holtmann, B., Meyer, M. and Thoenen, H (1996). Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic neurons and sensory neurons during the early postnatal development. Neuron 17, 75-89.[Medline]
Middleton, G., Nunez, G. and Davies, A. M (1996). Bax promotes neuronal survival and antogonises the survival effects of trophic factors. Development 122, 695-701.[Abstract]
Miller, T. M., Moulder, K. L., Knudson, C. M., Creedon, D. J., Deshmukh, M., Korsmeyer, S. J. and Johnson, E. M., Jr (1997). Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J. Cell Biol 139, 205-217.[Abstract/Free Full Text]
Minn, A. J., Boise, L. H. and Thompson, C. B (1996). Bcl-x(S) anatagonizes the protective effects of Bcl-x(L). J. Biol. Chem 271, 6306-6312.[Abstract/Free Full Text]
Motoyama, N., Wang, F., Roth, K. A., Sawa, H., Nakayama, K., Nakayama, K., Negishi, I., Senju, S., Zhang, Q., Fujii, S. and Loh, D. Y (1995). Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 267, 1506-1510.[Abstract/Free Full Text]
Pan, G., O'Rourke, K. and Dixit, V. M (1998). Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex. J. Biol. Chem 273, 5841-5845.[Abstract/Free Full Text]
Parsadanian, A. S., Cheng, Y., Keller-Peck, C. R., Holtzman, D. M. and Snider, W. D (1998). Bcl-xL is an antiapoptotic regulator for postnatal CNS neurons. J. Neurosci 18, 1009-1019.[Abstract/Free Full Text]
Pi\226on, L. G. P., Middleton, G. and Davies, A. M (1997). Bcl-2 is required for cranial sensory neuron survival at defined stages of embryonic development. Development 124, 4173-4178.[Abstract]
Pi\226on, L. G. P., Minichiello, L., Klein, R. and Davies, A. M (1996). Timing of neuronal death in trkA , trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling. Development 122, 3255-3261.[Abstract]
Qin, H., Srinivasula, S. M., Wu, G., Fernandes-Alnemri, T., Alnemri, E. S. and Shi, Y (1999). Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature 399, 549-557.[Medline]
Rosse, T., Olivier, R., Monney, L., Rager, M., Conus, S., Fellay, I., Jansen, B. and Borner, C (1998). Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c. Nature 391, 496-499.[Medline]
Shimizu, S., Narita, M. and Tsujimoto, Y (1999). Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 399, 483-487.[Medline]
Vaux, D. L. and Korsmeyer, S. J (1999). Cell death in development. Cell 96, 245-254.[Medline]
Vekrellis, K., McCarthy, M. J., Watson, A., Whitfield, J., Rubin, L. L. and Ham, J (1997). Bax promotes neuronal cell death and is downregulated during the development of the nervous system. Development 124, 1239-1249.[Abstract]
White, F. A., Keller-Peck, C. R., Knudson, C. M., Korsmeyer, S. J. and Snider, W. D (1998). Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J. Neurosci 18, 1428-1439.[Abstract/Free Full Text]
Wyatt, S. and Davies, A. M (1993). Regulation of expression of mRNAs encoding the nerve growth factor receptors p75 and trkA in developing sensory neurons. Development 119, 635-648.[Abstract]
Wyatt, S., Pi\226on, L. G. P., Ernfors, P. and Davies, A. M (1997). Sympathetic neuron survival and TrkA expression in NT3-deficient mouse embryos. EMBO J 16, 3115-3123.[Medline]
Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T. I., Jones, D. P. and Wang, X (1997). Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275, 1129-1132.[Abstract/Free Full Text]