RXR-alpha ablation in skin keratinocytes results in alopecia and epidermal alterations

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Asarnow, D. M., Kuziel, W. A., Bonyhadi, M., Tigelaar, R. E., Tucker, P. W. and Allison, J. P (1988). Limited diversity of gamma delta antigen receptor genes of Thy-1+ dendritic epidermal cells. Cell 55, 837-847.[Medline]

Austyn, J. M. and Gordon, S (1981). F4/80 a monoclonal antibody directed specifically against the mouse macrophage. Eur. J. Immunol 11, 805-.[Medline]

Billoni, N., Buan, B., Gautier, B., Gaillard, O., Mahe, Y. F. and Bernard, B. A (2000). Thyroid hormone receptor beta1 is expressed in the human hair follicle. Br. J. Dermatol 142, 645-652.[Medline]

Breuhahn, K., Mann, A., Muller, G., Wilhelmi, A., Schirmacher, P., Enk, A. and Blessing, M (2000). Epidermal overexpression of granulocyte-macrophage colony-stimulating factor induces both keratinocyte proliferation and apoptosis. Cell Growth Diff 11, 111-121.[Abstract/Free Full Text]

Brocard, J., Warot, X., Wendling, O., Messaddeq, N., Vonesch, J. L., Chambon, P. and Metzger, D (1997). Spatio-temporally controlled site-specific somatic mutagenesis in the mouse. Proc. Natl. Acad. Sci. USA 94, 14559-14563.[Abstract/Free Full Text]

Byrne, C., Tainsky, M. and Fuchs, E (1994). Programming gene expression in developing epidermis. Development 120, 2369-2383.[Abstract/Free Full Text]

Carroll, J. M., Romero, M. R. and Watt, F. M (1995). Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. Cell 83, 957-968.[Medline]

Chambon, P (1996). A decade of molecular biology of retinoic acid receptors. FASEB J 10, 940-945.[Abstract]

Charpin, C., Devictor, B., Bergeret, D., Andrac, L., Boulat, J., Horschowski, N., Lavaut, M. N. and Piana, L (1995). CD31 quantitative immunocytochemical assays in breast carcinomas. Correlation with current prognostic factors. Am. J. Clin. Pathol 103, 443-448.[Medline]

Chen, J. D. and Evans, R. M (1995). A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377, 454-457.[Medline]

Clifford, J., Chiba, H., Sobieszczuk, D., Metzger, D. and Chambon, P (1996). RXRalpha-null F9 embryonal carcinoma cells are resistant to the differentiation, anti-proliferative and apoptotic effects of retinoids. EMBO J 15, 4142-4155.[Medline]

DuBrul, E (1972). Fine structure of epidermal differentiation in the mouse. J. Exp. Zool 181, 145-158.[Medline]

Dupe, V., Davenne, M., Brocard, J., Dolle, P., Mark, M., Dierich, A., Chambon, P. and Rijli, F. M (1997). In vivo functional analysis of the Hoxa-1 3retinoic acid response element (3 RARE). Development 124, 399-410.[Abstract]

Elder, J. T., Astrom, A., Pettersson, U., Tavakkol, A., Christopher, E. M. G, Krust, A., Kastner, P., Chambon, P. and Voorhes, J. J (1992). Differential regulation of retinoic acid receptors and binding proteins in human skin. J. Invest. Dermatol 98, 673-679.[Medline]

Feil, R., Brocard, J., Mascrez, B., LeMeur, M., Metzger, D. and Chambon, P (1996). Ligand-activated site-specific recombination in mice. Proc. Natl. Acad. Sci. USA 93, 10887-10890.[Abstract/Free Full Text]

Feil, R., Wagner, J., Metzger, D. and Chambon, P (1997). Regulation of Cre recombinase activity by mutated oestrogen receptor ligand-binding domains. Biochem. Biophys. Res. Commun 237, 752-757.[Medline]

Feng, X., Peng, Z. H., Di, W., Li, X. Y., Rochette-Egly, C., Chambon, P., Voorhees, J. J. and Xiao, J. H (1997). Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids. Genes Dev 11, 59-71.[Abstract/Free Full Text]

Fisher, G. J., Talwar, H. S., Xiao, J. H., Datta, S. C., Reddy, A. P., Gaub, M. P., Rochette-Egly, C., Chambon, P. and Voorhees, J. J (1994). Immunological identification and functional quantitation of retinoic acid and retinoid X receptor proteins in human skin. J. Biol. Chem 269, 20629-20635.[Abstract/Free Full Text]

Fisher, G. J. and Voorhees, J. J (1996). Molecular mechanisms of retinoid actions in skin. FASEB J 10, 1002-1013.[Abstract]

Fuchs, E (1997). Of mice and men: genetic disorders of the cytoskeleton. Mol. Biol.Cell 8, 189-203.[Abstract]

Giguere, V (1999). Orphan nuclear receptors: from gene to function. Endocr. Rev 20, 689-725.[Abstract/Free Full Text]

Hanley, K., Jiang, Y., Crumrine, D., Bass, N. M., Appel, R., Elias, P. M., Williams, M. L. and Feingold, K. R (1997). Activators of the nuclear hormone receptors PPARand FXR accelerate the development of the fetal epidermal permeability barrier. J. Clin. Invest 100, 705-712.[Medline]

Hanley, K., Jiang, Y., He, S. S., Friedman, M., Elias, P. M., Bikle, D. D., Williams, M. L. and Feingold, K. R (1998). Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPAR. J. Invest. Dermatol 110, 368-375.[Medline]

Hanley, K., Ng, D. C., He, S. S., Lau, P., Min, K., Elias, P. M., Bikle, D. D., Mangelsdorf, D. J., Williams, M. L. and Feingold, K. R (2000). Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription. J. Invest. Dermatol 114, 545-553.[Medline]

Hanley, K., K\232muves, L. G., Ng, D. C., Schoonjans, K., He, S. S., Lau, P., Bikle, D. D., Williams, M. L., Elias, P. M., Auwerx, J. and Feingold, K. R (2000). Farnesol stimulates differentiation in epidermal keratinocytes via PPAR. J. Biol. Chem 275, 11484-11491.[Abstract/Free Full Text]

Hardman, M. J., Sisi, P., Banbury, D. N. and Byrne, C (1998). Patterned acquisition of skin barrier function during development. Development 125, 1541-1552.[Abstract]

Hardy, M. H (1992). The secret life of the hair follicle. Trends Genet 8, 55-61.[Medline]

Hirobe T (1995). Structure and function of melanocytes: microscopic morphology and cell biology of mouse melanocytes in the epidermis and hair follicle. Histol. Histopathol 10, 223-237.[Medline]

Imakado, S., Bickenbach, J. R., Bundman, D. S., Rothnagel, J. A., Attar, P. S., Wang, X. J., Walczak, V. R., Wisniewski, S., Pote, J. and Gordon, J. S (1995). Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function. Genes Dev 9, 317-329.[Abstract/Free Full Text]

Indra, A. K., Warot, X., Brocard, J., Bornert, J. M., Xiao, J. H., Chambon, P. and Metzger, D (1999). Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ERTand Cre-ERT2recombinases. Nucleic Acids Res 27, 4324-4327.[Abstract/Free Full Text]

Kastner, P., Grondona, J. M., Mark, M., Gansmuller, A., LeMeur, M., Decimo, D., Vonesch, J. L., Dolle, P. and Chambon, P (1994). Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell 78, 987-1003.[Medline]

Kastner, P., Mark, M. and Chambon, P (1995). Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?. Cell 83, 859-869.[Medline]

Kastner, P., Mark, M., Leid, M., Gansmuller, A., Grondona, J. M., Decimo, D., Krezel, W., Dierich, A. and Chambon, P (1996). Abnormal spermatogenesis in RXRmutant mice. Genes Dev 10, 80-92.[Abstract/Free Full Text]

Kastner, P., Mark, M., Ghyselinck, N., Krezel, W., Dupe, V., Grondona, J. M. and Chambon, P (1997). Genetic evidence that the retinoid signal is tranduced by heterodimeric RXR/RAR functional units during mouse development. Development 124, 313-326.[Abstract]

Katz, S. I., Tamaki, K. and Sachs, D. H (1979). Epidermal langerhans cellsare derived from cells originating in bone marrow. Nature 282, 324-326.[Medline]

K\232muves, L. G., Hanley, K., Jiang, Y., Elias, P. M., Williams, M. L. and Feingold, K. R (1998). Ligands and activators of nuclear hormone receptors regulate epidermal differentiation during fetal rat skin development. J. Invest. Dermatol 111, 429-433.[Medline]

Leid, M., Kastner, P., Lyons, R., Nakshatri, H., Saunders, M., Zacharewski, T., Chen, J. Y., Staub, A., Garnier, J. M., Mader, S. and Chambon, P (1992). Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell 68, 377-395.[Medline]

Li, Y. C., Pirro, A. E., Amling, M., Delling, G., Baron, R., Bronson, R. and Demay, M. B (1997). Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia. Proc. Natl. Acad. Sci. USA 94, 9831-9835.[Abstract/Free Full Text]

Li, Y. C., Amling, M., Pirro, A. E., Priemel, M., Meuse, J., Baron, R., Delling, G. and Demay, M. B (1998). Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice. Endocrinology 139, 4391-4396.[Abstract/Free Full Text]

Lohnes, D., Kastner, P., Dierich, A., Mark, M., LeMeur, M. and Chambon, P., (1993). Function of retinoic acid receptorin the mouse. Cell 73, 643-658.[Medline]

Lohnes, D., Mark M., Mendelsohn, C., Dolle, P., Dierich, A., Gorry, P., Gansmuller, A. and Chambon, P (1994). Function of the retinoic acid receptors (RARs) during development. (I) Cranofacial and skeletal abnormalities in RAR double mutants. Development 120, 2723-2748.[Abstract]

Lufkin, T., Lohnes, D., Mark, M., Dierich, A., Gorry, P., Gaub, M. P., LeMeur, M. and Chambon P (1993). High postnatal lethality and testis degeneration in retinoic acid receptormutant mice. Proc. Natl. Acad. Sci. USA 90, 7225-7229.[Abstract/Free Full Text]

Malloy, P. J., Pike, W. and Feldman, D (1999). The Vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets. Endocr. Rev 20, 156-188.[Abstract/Free Full Text]

Mangelsdorf, D. J., Borgmeyer, U., Heyman, R. A., Zhou, J. Y., Ong, E. S., Oro, A. E., Kakizuka, A. and Evans, R. M (1992). Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev 6, 329-344.[Abstract/Free Full Text]

Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schutz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M. and Chambon, P (1995). The nuclear receptor superfamily: the second decade. Cell 83, 835-839.[Medline]

Mascrez, B., Mark, M., Dierich, A., Ghyselinck, N. B., Kastner, P. and Chambon P (1998). The RXRligand-dependent activation function 2 (AF-2) is important for mouse development. Development 125, 4691-4707.[Abstract]

Metzger, D., Clifford, J., Chiba, H. and Chambon, P (1995). Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc. Natl. Acad. Sci. USA 92, 6991-6995.[Abstract/Free Full Text]

Oro, A. E. and Scott, M. P (1998). Splitting hairs: dissecting roles of signaling systems in epidermal development. Cell 95, 575-578.[Medline]

Panteleyev, A. A., Paus, R., Ahmad, W., Sundeberg, J. P. and Christiano, A. M (1998). Molecular and functional aspects of the hairless (hr) gene in laboratory rodents and humans. Exp. Dermatol 7, 249-267.[Medline]

Paus, R. and Cotsarelis, G (1999). The biology of hair follicles. New Engl. J. Med 341, 491-497.[Free Full Text]

Peters, J. M., Lee, S. S. T., Li, W., Ward, J. M., Gavrilova, O., Everett, C., Reitman, M. L., Dudson, L. D. and Gonzalez, F. J (2000). Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor( ). Mol. Cell Biol 20, 5119-5128.[Abstract/Free Full Text]

Porter, R. M., Reichelt, J., Lunny, D. P., Magin, T. M. and Lane, E. B (1998). The relationship between hyperproliferation and epidermal thickening in a mouse model for BCIE. J. Invest. Dermatol 110, 951-957.[Medline]

Reichrath, J., Schilli, M., Kerber, A., Bahmer, F. A., Czarnetzki, B. M. and Paus, R (1994). Hair follicle expression of 1,25-dihydroxyvitamin D3 receptors during the murine hair cycle. Br. J. Dermatol 131, 477-482.[Medline]

Reichrath, J., Munssinger, T., Kerber, A., Rochette-Egly, C., Chambon, P., Bahmer, F. A. and Baum, H. P (1995). In situ detection of retinoid-X receptor expression in normal and psoriatic human skin. Br. J. Dermatol 133, 168-175.[Medline]

Rochette-Egly, C., Lutz, Y., Pfister, V., Heyberger, S., Scheuer, I., Chambon, P. and Gaub, M. P (1994). Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies. Biochem. Biophys. Res. Commun 204, 525-536.[Medline]

Roos, T. C., Jugert, F. K., Merk, H. F. and Bickers, D. R (1998). Retinoid metabolism in the skin. Pharmacol. Rev 50, 315-333.[Abstract/Free Full Text]

Sakai, Y. and Demay, M. B (2000). Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice. Endocrinology 141, 2043-2049.[Abstract/Free Full Text]

Saitou, M., Sugai, S., Tanaka, T., Shimouchi, K., Fuchs, E., Narumiya, S. and Kakizuka, A (1995). Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor. Nature 374, 159-162.[Medline]

Schluter, C., Duchrow, M., Wohlenberg, C., Becker, M. H. G., Key, G., Flad, H.-D. and Gerdes, F (1993). The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins. J. Cell. Biol 123, 513-522.[Abstract/Free Full Text]

Soriano P (1999). Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet 21, 70-71.[Medline]

Springer, T. A (1990). Adhesion receptors of the immune system. Nature 346, 425-434.[Medline]

Sucov, H. M., Dyson, E., Gumeringer, C. L., Price, J., Chien, K. R. andEvans, R. M (1994). RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev 8, 1007-1018.[Abstract/Free Full Text]

Sundberg, J. P. and King, L. E (1996). Mouse models for the study of human hair loss. Dermatol. Clin 14, 619-632.[Medline]

Swiggard, W. J., Mirza, A., Nussenzweig, M. C. and Steinman, R. M (1995). DEC-205, a 205-kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: purification, characterization, and N-terminal amino acid sequence. Cell Immunol 165, 302-311.[Medline]

Vasioukhin, V., Degenstein, L., Wise, B. and Fuchs, E (1999). The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin. Proc. Natl. Acad. Sci. USA 96, 8551-8556.[Abstract/Free Full Text]

Vassar, R., Rosenberg, M., Ross, S., Tyner, A. and Fuchs, E (1989). Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice. Proc. Natl. Acad. Sci. USA 86, 1563-1567.[Abstract/Free Full Text]

Wan Y-J. Y., An, D., Cai, Y., Repa, J. J., Chen, T. H. P., Flores, M., Postic, M., Magnuson, M. A., Chen, J., Chien, K. R. et al (2000). Hepatocyte-specific mutation establishes retinoid X receptoras a heterodimeric integrator of multiple physiological processes in the liver. Mol. Cell Biol 20, 4436-4444.[Abstract/Free Full Text]

Wang, X., Zinkel, S., Polonsky, K. and Fuchs, E (1997). Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy. Proc. Natl. Acad. Sci. USA 94, 219-226.[Abstract/Free Full Text]

Wendling, O., Chambon, P. and Mark, M (1999). Retinoid X receptors are essential for early mouse development and placentogenesis. Proc. Natl. Acad. Sci. USA 96, 547-551.[Abstract/Free Full Text]

Xiao, J. H., Feng, X., Di, W., Peng, Z. H., Li, L. A., Chambon, P. and Voorhees, J. J (1999). Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors. EMBO J 18, 1539-1548.[Medline]

Yen, P. M., Liu, Y., Sugawara, A. and Chin, W. W (1996). Vitamin D receptors repress basal transcription and exert dominant negative activity on triiodothyronine-mediated transcriptional activity. J. Biol. Chem 271, 10910-10916.[Abstract/Free Full Text]

Yoshizawa, T., Handa, Y., Uematsu, Y., Takeda, S., Sekine, K., Yoshihara, Y., Kawakami, T., Arioka, K., Sato, H., Uchiyama, Y. et al (1997). Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nat. Genet 16, 391-396.[Medline]

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[Abstract] [Full Text] [PDF]

M. Mori, D. Metzger, S. Picaud, C. Hindelang, M. Simonutti, J. Sahel, P. Chambon, and M. Mark
Retinal Dystrophy Resulting from Ablation of RXR{alpha} in the Mouse Retinal Pigment Epithelium
Am. J. Pathol., February 1, 2004; 164(2): 701 - 710.
[Abstract] [Full Text] [PDF]

L. A. Hansen, D. Brown, V. Virador, T. Tanaka, F. Andreola, K. Strain, B. Dancheck, R. Riley, J. M. Arbeit, L. M. De Luca, et al.
A PMLRARA Transgene Results in a Retinoid-deficient Phenotype Associated with Enhanced Susceptibility to Skin Tumorigenesis
Cancer Res., September 1, 2003; 63(17): 5257 - 5265.
[Abstract] [Full Text] [PDF]

L. Alonso and E. Fuchs
Stem cells in the skin: waste not, Wnt not
Genes & Dev., May 15, 2003; 17(10): 1189 - 1200.
[Full Text] [PDF]

G. M. Zinser, J. P. Sundberg, and J. Welsh
Vitamin D3 receptor ablation sensitizes skin to chemically induced tumorigenesis
Carcinogenesis, December 1, 2002; 23(12): 2103 - 2109.
[Abstract] [Full Text] [PDF]

K. Prufer and J. Barsony
Retinoid X Receptor Dominates the Nuclear Import and Export of the Unliganded Vitamin D Receptor
Mol. Endocrinol., August 1, 2002; 16(8): 1738 - 1751.
[Abstract] [Full Text] [PDF]

C. K. Kaufman, S. Sinha, D. Bolotin, J. Fan, and E. Fuchs
Dissection of a Complex Enhancer Element: Maintenance of Keratinocyte Specificity but Loss of Differentiation Specificity
Mol. Cell. Biol., June 15, 2002; 22(12): 4293 - 4308.
[Abstract] [Full Text] [PDF]

M. Mori, D. Metzger, J.-M. Garnier, P. Chambon, and M. Mark
Site-Specific Somatic Mutagenesis in the Retinal Pigment Epithelium
Invest. Ophthalmol. Vis. Sci., May 1, 2002; 43(5): 1384 - 1388.
[Abstract] [Full Text] [PDF]

L. Michalik, B. Desvergne, N. S. Tan, S. Basu-Modak, P. Escher, J. Rieusset, J. M. Peters, G. Kaya, F. J. Gonzalez, J. Zakany, et al.
Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR){alpha} and PPAR{beta} mutant mice
J. Cell Biol., August 20, 2001; 154(4): 799 - 814.
[Abstract] [Full Text] [PDF]

T. Imai, M. Jiang, P. Kastner, P. Chambon, and D. Metzger
Selective ablation of retinoid X receptor alpha in hepatocytes impairs their lifespan and regenerative capacity
PNAS, April 10, 2001; 98(8): 4581 - 4586.
[Abstract] [Full Text] [PDF]

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