spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Methot, N.
Right arrow Articles by Basler, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Methot, N.
Right arrow Articles by Basler, K.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?
Adams, M. D., Celniker, S. E., Holt, R. A., Evans, C. A., Gocayne, J. D., Amanatides, P. G., Scherer, S. E., Li, P. W., Hoskins, R. A., Galle, R. F. et al. ( (2000). The genome sequence of Drosophila melanogaster. Science 287, 2185-2195.[Abstract/Free Full Text]

Alcedo, J. and Noll, M (1997). Hedgehog and its Patched-Smoothened receptor complex: a novel signalling mechanism at the cell surface. Biol. Chem 378, 583-590.

Alves, G., Limbourg-Bouchon, B., Tricoire, H., Brissard-Zahraoui, J., Lamour-Isnard, C. and Busson, D (1998). Modulation of Hedgehog target gene expression by the Fused serine-threonine kinase in wing imaginal discs. Mech. Dev 78, 17-31.[Medline]

Aza-Blanc, P., Ramirez-Weber, F. A., Laget, M. P., Schwartz, C. and Kornberg, T. B (1997). Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor. Cell 89, 1043-1053.[Medline]

Aza-Blanc, P. and Kornberg, T. B (1999). Ci \320 a complex transducer of the Hedgehog signal. Trends Genet 15, 458-462.[Medline]

Baker, N. E (1988). Localization of transcripts from the wingless gene in whole Drosophila embryos. Development 103, 289-298.[Abstract]

Bejsovec, A. and Martinez Arias, A (1991). Roles of wingless in patterning the larval epidermis of Drosophila. Development 113, 471-485.[Abstract]

Bejsovec, A. and Wieschaus, E (1993). Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. Development 119, 501-517.[Abstract]

Blair, S. S (1992). engrailed expression in the anterior lineage compartment of the developing wing blade of Drosophila. Development 115, 21-33.[Abstract]

Blair, S. S. and Ralston, A (1997). Smoothened-mediated Hedgehog signalling is required for the maintenance of the anterior-posterior lineage restriction in the developing wing of Drosophila. Development 124, 4053-4063.[Abstract]

Capdevila, J., Estrada, M. P., Sanchez-Herrero, E. and Guerrero, I (1994). The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development. EMBO J 13, 71-82.[Medline]

Cavallo, R. A., Cox, R. T., Moline, M. M., Roose, J., Polevoy, G. A., Clevers, H., Peifer, M. and Bejsovec, A (1998). Drosophila Tcf and Groucho interact to repress Wingless signalling activity. Nature 395, 604-608.[Medline]

Chen, Y. and Struhl, G (1996). Dual roles for patched in sequestering and transducing Hedgehog. Cell 87, 553-563.[Medline]

Cole, E. S. and Palka, J (1982). The pattern of campaniform sensilla on the wing and haltere of Drosophila melanogaster and several of its homeotic mutants. J. Embryol. Exp. Morphol 71, 41-61.[Medline]

Dahmann, C. and Basler, K (2000). Opposing transcriptional outputs of Hedgehog signaling and engrailed control compartmental cell sorting at the Drosophila A/P boundary. Cell 100, 411-422.[Medline]

Denhardt, D. T (1996). Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling. Biochem. J 318, 729-747.[Medline]

DiNardo, S., Sher, E., Heemskerk-Jongens, J., Kassis, J. A. and O'Farrell, P. H (1988). Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis. Nature 332, 604-609.[Medline]

Dominguez, M., Brunner, M., Hafen, E. and Basler, K (1996). Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science 272, 1621-1625.[Abstract]

Forbes, A. J., Nakano, Y., Taylor, A. M. and Ingham, P. W (1993). Genetic analysis of hedgehog signalling in the Drosophila embryo. Development 118, 115-124.

Gallet, A., Angelats, C., Kerridge, S. and Therond, P.P (2000). Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila. Development 127, 5509-5522.[Abstract]

Goodrich, L. V., Johnson, R. L., Milenkovic, L., McMahon, J. A. and Scott, M. P (1996). Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev 10, 301-312.[Abstract/Free Full Text]

Gritzan, U., Hatini, V. and DiNardo, S (1999). Mutual antagonism between signals secreted by adjacent wingless and engrailed cells leads to specification of complementary regions of the Drosophila parasegment. Development 126, 4107-4115.[Abstract]

Hammerschmidt, M., Brook, A. and McMahon, A. P (1997). The world according to hedgehog. Trends Genet 13, 14-21.[Medline]

Hidalgo, A (1994). Three distinct roles for the engrailed gene in Drosophila wing development. Curr. Biol 4, 1087-1098.[Medline]

Hidalgo, A. and Ingham, P (1990). Cell patterning in the Drosophila segment: spatial regulation of the segment polarity gene patched. Development 110, 291-301.[Abstract]

Ingham, P. W (1993). Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo. Nature 366, 560-562.[Medline]

Ingham, P. W (1998). Transducing Hedgehog: the story so far. EMBO J 17, 3505-3511.[Medline]

Ingham, P. W., Baker, N. E. and Martinez-Arias, A (1988). Regulation of segment polarity genes in the Drosophila blastoderm by fushi tarazu and even skipped. Nature 331, 73-75.[Medline]

Ingham, P. W., Taylor, A. M. and Nakano, Y (1991). Role of the Drosophila patched gene in positional signalling. Nature 353, 184-187.[Medline]

Kingsley, D. M (1994). The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 8, 133-146.[Free Full Text]

Krishnan, V., Elberg, G., Tsai, M. J. and Tsai, S. Y (1997). Identification of a novel sonic hedgehog response element in the chicken ovalbumin upstream promoter-transcription factor II promoter. Mol. Endocrinol 11, 1458-1466.[Abstract/Free Full Text]

Krishnan, V., Pereira, F. A., Qiu, Y., Chen, C. H., Beachy, P. A., Tsai, S. Y. and Tsai, M. J (1997). Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase. Science 278, 1947-1950.[Abstract/Free Full Text]

Lawrence, P. A., Casal, J. and Struhl, G (1999). The hedgehog morphogen and gradients of cell affinity in the abdomen of Drosophila. Development 126, 2441-2449.[Abstract]

Lawrence, P. A. and Struhl, G (1996). Morphogens, compartments, and pattern: lessons from Drosophila ?. Cell 85, 951-961.[Medline]

Lee, J. J., von Kessler, D. P., Parks, S. and Beachy, P. A (1992). Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog. Cell 71, 33-50.[Medline]

Lessing, D. and Nusse, R (1998). Expression of wingless in the Drosophila embryo: a conserved cis-acting element lacking conserved Ci-binding sites is required for patched -mediated repression. Development 125, 1469-1476.[Abstract]

Lewis, K. E., Drossopoulou, G., Paton, I. R., Morrice, D. R., Robertson, K. E., Burt, D. W., Ingham, P. W. and Tickle, C (1999). Expression of ptc and gli genes in talpid3 suggests bifurcation in Shh pathway. Development 126, 2397-2407.[Abstract]

Luschnig, S., Krauss, J., Bohmann, K., Desjeux, I. and Nusslein-Volhard, C (2000). The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases. Mol. Cell 5, 231-241.

Marigo, V., Scott, M. P., Johnson, R. L., Goodrich, L. V. and Tabin, C. J (1996). Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb. Development 122, 1225-1233.[Abstract]

Mason, I. J (1994). The ins and outs of fibroblast growth factors. Cell 78, 547-552.[Medline]

McMahon, A. P (2000). More surprises in the Hedgehog signaling pathway. Cell 100, 185-188.[Medline]

Methot, N. and Basler, K (1999). Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. Cell 96, 819-831.[Medline]

Methot, N. and Basler, K (2000). Suppressor of Fused opposes Hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. Development 127, 4001-4010.[Abstract]

Morel, V. and Schweisguth, F (2000). Repression by suppressor of hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo. Genes Dev 14, 377-388.[Abstract/Free Full Text]

Muller, B. and Basler, K (2000). The repressor and activator forms of Cubitus interruptus control Hedgehog target genes through common generic Gli-binding sites. Development 127, 2999-3007.[Abstract]

Neumann, C. and Cohen, S (1997). Morphogens and pattern formation. BioEssays 19, 721-729.[Medline]

Nusslein-Volhard, C. and Wieschaus, E (1980). Mutation affecting segment number and polarity in Drosophila. Nature 287, 795-801.[Medline]

Phillips, R. G., Roberts, I. J., Ingham, P. W. and Whittle, J. R (1990). The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs. Development 110, 105-114.[Abstract]

Ram\222rez-Weber, F.-A., Casso, D. J., Aza-Blanc, P., Tabata, T. and Kornberg, T. B (2000). Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc. Mol. Cell 6, 479-485.

Rodriguez, I. and Basler, K (1997). Control of compartmental affinity boundaries by hedgehog. Nature 389, 614-618.[Medline]

Rubin, G. M., et al. ( (2000). Comparative genomics of the eukaryotes. Science 287, 2204-2215.[Abstract/Free Full Text]

Ruiz i Altaba, A (1999). Gli proteins and Hedgehog signaling: development and cancer. Trends Genet 15, 418-425.[Medline]

Sanchez-Herrero, E., Couso, J. P., Capdevila, J. and Guerrero, I (1996). The fu gene discriminates between pathways to control dpp expression in Drosophila imaginal discs. Mech. Dev 55, 159-170.[Medline]

Sanicola, M., Sekelsky, J., Elson, S. and Gelbart, W. M (1995). Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed. Genetics 139, 745-756.[Abstract]

Sanson, B., Alexandre, C., Fascetti, N. and Vincent, J. P (1999). engrailed and hedgehog make the range of Wingless asymmetric in Drosophila embryos. Cell 98, 207-216.[Medline]

Schamel, W. W. and Dick, T. P (1996). Signal transduction: specificity of growth factors explained by parallel distributed processing. Med. Hypoth 47, 249-255.[Medline]

Schweitzer, R. and Shilo, B.-Z (1997). A thousand and one roles for the Drosophila EGF receptor. Trends Genet 13, 191-196.[Medline]

Selbie, L. A. and Hill, S. J (1998). G protein-coupled-receptor cross-talk: the fine-tuning of multiple receptor-signalling pathways. Trends Pharmacol. Sci 19, 87-93.[Medline]

Slusarski, D. C., Motzny, C. K. and Holmgren, R (1995). Mutations that alter the timing and pattern of cubitus interruptus gene expression in Drosophila melanogaster. Genetics 139, 229-240.[Abstract]

Strigini, M. and Cohen, S. M (1997). A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing. Development 124, 4697-4705.[Abstract]

Suzuki, T. and Saigo, K (2000). Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus. Development 127, 1531-1540.[Abstract]

Tabata, T. and Kornberg, T. B (1994). Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.[Medline]

Tabata, T., Schwartz, C., Gustavson, E., Ali, Z. and Kornberg, T. B (1995). Creating a Drosophila wing de novo, the role of engrailed , and the compartment border hypothesis. Development, 121, 3359-3369.[Abstract]

Therond, P.P., Limbourg-Bouchon, B., Gallet, A., Dussilol, F., Pietri, T., van den Heuvel, M. and Tricoire, H (1999). Differential requirements of the Fused kinase for Hedgehog signaling in the Drosophila embryo. Development 126, 4039-4051.[Abstract]

Waltzer, L. and Bienz, M (1998). Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature 395, 521-525.[Medline]

Wodarz, A. and Nusse, R (1998). Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol 14, 59-88.[Medline]

Xu, T. and Rubin, G. M (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.[Abstract]

Zecca, M., Basler, K. and Struhl, G (1995). Sequential organizing activities of engrailed , hedgehog and decapentaplegic in the Drosophila wing. Development 121, 2265-2278.[Abstract]

Zwick, E., Wallasch, C., Daub, H. and Ullrich, A (1999). Distinct calcium-dependent pathways of epidermal growth factor receptor transactivation and PYK2 tyrosine phosphorylation in PC12 cells. J. Biol. Chem 274, 20989-20996.[Abstract/Free Full Text]


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
Mol. Cell. Biol.Home page
M. Galletti, S. Riccardo, F. Parisi, C. Lora, M. K. Saqcena, L. Rivas, B. Wong, A. Serra, F. Serras, D. Grifoni, et al.
Identification of Domains Responsible for Ubiquitin-Dependent Degradation of dMyc by Glycogen Synthase Kinase 3{beta} and Casein Kinase 1 Kinases
Mol. Cell. Biol., June 15, 2009; 29(12): 3424 - 3434.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
A. N. Hoover, A. Wynkoop, H. Zeng, J. Jia, L. A. Niswander, and A. Liu
C2cd3 is required for cilia formation and Hedgehog signaling in mouse
Development, December 15, 2008; 135(24): 4049 - 4058.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
M. Varjosalo and J. Taipale
Hedgehog signaling
J. Cell Sci., January 1, 2007; 120(1): 3 - 6.
[Full Text] [PDF]


Home page
GeneticsHome page
Q. Zhou, S. Apionishev, and D. Kalderon
The Contributions of Protein Kinase A and Smoothened Phosphorylation to Hedgehog Signal Transduction in Drosophila melanogaster
Genetics, August 1, 2006; 173(4): 2049 - 2062.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
M. C. Hu, R. Mo, S. Bhella, C. W. Wilson, P.-T. Chuang, C.-c. Hui, and N. D. Rosenblum
GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis
Development, February 1, 2006; 133(3): 569 - 578.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
E. G. Huntzicker, I. S. Estay, H. Zhen, L. A. Lokteva, P. K. Jackson, and A. E. Oro
Dual degradation signals control Gli protein stability and tumor formation
Genes & Dev., February 1, 2006; 20(3): 276 - 281.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
L. Koziel, M. Wuelling, S. Schneider, and A. Vortkamp
Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation
Development, December 1, 2005; 132(23): 5249 - 5260.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
V. Nguyen, A. L. Chokas, B. Stecca, and A. R. i Altaba
Cooperative requirement of the Gli proteins in neurogenesis
Development, July 15, 2005; 132(14): 3267 - 3279.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
K. S. Ho, K. Suyama, M. Fish, and M. P. Scott
Differential regulation of Hedgehog target gene transcription by Costal2 and Suppressor of Fused
Development, March 15, 2005; 132(6): 1401 - 1412.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
C. A. Callahan, T. Ofstad, L. Horng, J. K. Wang, H. H. Zhen, P. A. Coulombe, and A. E. Oro
MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription
Genes & Dev., November 15, 2004; 18(22): 2724 - 2729.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
M. Merchant, F. F. Vajdos, M. Ultsch, H. R. Maun, U. Wendt, J. Cannon, W. Desmarais, R. A. Lazarus, A. M. de Vos, and F. J. de Sauvage
Suppressor of Fused Regulates Gli Activity through a Dual Binding Mechanism
Mol. Cell. Biol., October 1, 2004; 24(19): 8627 - 8641.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
Q. Lei, A. K. Zelman, E. Kuang, S. Li, and M. P. Matise
Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord
Development, August 1, 2004; 131(15): 3593 - 3604.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
L. Lum and P. A. Beachy
The Hedgehog Response Network: Sensors, Switches, and Routers
Science, June 18, 2004; 304(5678): 1755 - 1759.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
K. Sekimizu, N. Nishioka, H. Sasaki, H. Takeda, R. O. Karlstrom, and A. Kawakami
The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling
Development, June 1, 2004; 131(11): 2521 - 2532.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
O. V. Bulgakov, J. T. Eggenschwiler, D.-H. Hong, K. V. Anderson, and T. Li
FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues
Development, May 1, 2004; 131(9): 2149 - 2159.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
L. Buttitta, R. Mo, C.-C. Hui, and C.-M. Fan
Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction
Development, December 22, 2003; 130(25): 6233 - 6243.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
C. W. Larsen, E. Hirst, C. Alexandre, and J.-P. Vincent
Segment boundary formation in Drosophila embryos
Development, December 1, 2003; 130(23): 5625 - 5635.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
L. Schweizer, D. Nellen, and K. Basler
Requirement for Pangolin/dTCF in Drosophila Wingless signaling
PNAS, May 13, 2003; 100(10): 5846 - 5851.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
R. O. Karlstrom, O. V. Tyurina, A. Kawakami, N. Nishioka, W. S. Talbot, H. Sasaki, and A. F. Schier
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development
Development, April 15, 2003; 130(8): 1549 - 1564.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
C. B. Bai, W. Auerbach, J. S. Lee, D. Stephen, and A. L. Joyner
Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway
Development, March 12, 2003; 129(20): 4753 - 4761.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
M. Persson, D. Stamataki, P. te Welscher, E. Andersson, J. Bose, U. Ruther, J. Ericson, and J. Briscoe
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity
Genes & Dev., November 15, 2002; 16(22): 2865 - 2878.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
P. te Welscher, A. Zuniga, S. Kuijper, T. Drenth, H. J. Goedemans, F. Meijlink, and R. Zeller
Progression of Vertebrate Limb Development Through SHH-Mediated Counteraction of GLI3
Science, October 25, 2002; 298(5594): 827 - 830.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
S. Barolo and J. W. Posakony
Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling
Genes & Dev., May 15, 2002; 16(10): 1167 - 1181.
[Full Text] [PDF]


Home page
DevelopmentHome page
J. Bai and D. Montell
Eyes Absent, a key repressor of polar cell fate during Drosophila oogenesis
Development, January 12, 2002; 129(23): 5377 - 5388.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
C. B. Bai and A. L. Joyner
Gli1 can rescue the in vivo function of Gli2
Development, December 15, 2001; 128(24): 5161 - 5172.
[Abstract] [Full Text] [PDF]


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Methot, N.
Right arrow Articles by Basler, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Methot, N.
Right arrow Articles by Basler, K.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?