spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online 24 January 2007
doi: 10.1242/dev.000497

Development 134, 813-823 (2007)
Published by The Company of Biologists 2007
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
dev.000497v1
134/5/813    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chitwood, D. H.
Right arrow Articles by Timmermans, M. C. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chitwood, D. H.
Right arrow Articles by Timmermans, M. C. P.

Review

Establishing leaf polarity: the role of small RNAs and positional signals in the shoot apex

Daniel H. Chitwood1,2, Mengjuan Guo1, Fabio T. S. Nogueira1 and Marja C. P. Timmermans1,2,*

1 Cold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724, USA.
2 Watson School of Biological Sciences, One Bungtown Road, Cold Spring Harbor, NY 11724, USA.

* Author for correspondence (e-mail: timmerma{at}cshl.edu)

SUMMARY

The flattening of leaves results from the juxtaposition of upper (adaxial) and lower (abaxial) domains in the developing leaf primordium. The adaxial-abaxial axis reflects positional differences in the leaf relative to the meristem and is established by redundant genetic pathways that interpret this asymmetry through instructive, possibly non-cell autonomous, signals. Small RNAs have been found to play a crucial role in this process, and specify mutually antagonistic fates. Here, we review both classical and recently-discovered factors that contribute to leaf polarity, as well as the candidate positional signals that their existence implies.




This article has been cited by other articles:


Home page
 DevelopmentHome page
G. Coupland
Mechanisms and variation in plant development: sorting the wood from the trees in Vermont
Development, December 1, 2008; 135(23): 3813 - 3816.
[Abstract] [Full Text] [PDF]


© The Company of Biologists Ltd 2007