spacer gif spacer gif spacer gif spacer gif ARCHIVE ANNOUNCEMENT! spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search    

The fully linked HTML version of this article has now been published.
Development ePress online publication date 13 Aug 2003
doi: 10.1242/dev.00681

This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
dev.00681v1
130/20/4859    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zhang, F.
Right arrow Articles by Lloyd, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhang, F.
Right arrow Articles by Lloyd, A.

Research article

A network of redundant bHLH proteins functions in all TTG1-dependent pathways of Arabidopsis


Fan Zhang, Antonio Gonzalez, Mingzhe Zhao, C. Thomas Payne, and Alan Lloyd*
* Author for correspondence (e-mail: lloyd{at}uts.cc.utexas.edu)

GLABRA3 (GL3) encodes a bHLH protein that interacts with the WD repeat protein, TTG1. GL3 overexpression suppresses the trichome defect of the pleiotropic ttg1 mutations. However, single gl3 mutations only affect the trichome pathway with a modest trichome number reduction. A novel unlinked bHLH-encoding locus is described here, ENHANCER OF GLABRA3 (EGL3). When mutated, egl3 gives totally glabrous plants only in the gl3 mutant background. The double bHLH mutant, gl3 egl3, has a pleiotropic phenotype like ttg1 having defective anthocyanin production, seed coat mucilage production, and position-dependent root hair spacing. Furthermore, the triple bHLH mutant, gl3 egl3 tt8, phenocopies the ttg1 mutation. Yeast two-hybrid and plant overexpression studies show that EGL3, like GL3, interacts with TTG1, the myb proteins GL1, PAP1 and 2, CPC and TRY, and it will form heterodimers with GL3. These results suggest a combinatorial model for TTG1-dependent pathway regulation by this trio of partially functionally redundant bHLH proteins.


This article has been cited by other articles:


Home page
 J Exp BotHome page
X.-X. Shangguan, B. Xu, Z.-X. Yu, L.-J. Wang, and X.-Y. Chen
Promoter of a cotton fibre MYB gene functional in trichomes of Arabidopsis and glandular trichomes of tobacco
J. Exp. Bot., October 1, 2008; 59(13): 3533 - 3542.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
R. A. E. Laitinen, M. Ainasoja, S. K. Broholm, T. H. Teeri, and P. Elomaa
Identification of target genes for a MYB-type anthocyanin regulator in Gerbera hybrida
J. Exp. Bot., October 1, 2008; 59(13): 3691 - 3703.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Y. Pang, G. J. Peel, S. B. Sharma, Y. Tang, and R. A. Dixon
A transcript profiling approach reveals an epicatechin-specific glucosyltransferase expressed in the seed coat of Medicago truncatula
PNAS, September 16, 2008; 105(37): 14210 - 14215.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
M. Zhao, K. Morohashi, G. Hatlestad, E. Grotewold, and A. Lloyd
The TTG1-bHLH-MYB complex controls trichome cell fate and patterning through direct targeting of regulatory loci
Development, June 1, 2008; 135(11): 1991 - 1999.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
A. Macquet, M.-C. Ralet, O. Loudet, J. Kronenberger, G. Mouille, A. Marion-Poll, and H. M. North
A Naturally Occurring Mutation in an Arabidopsis Accession Affects a {beta}-D-Galactosidase That Increases the Hydrophilic Potential of Rhamnogalacturonan I in Seed Mucilage
PLANT CELL, December 1, 2007; 19(12): 3990 - 4006.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
K. Morohashi, M. Zhao, M. Yang, B. Read, A. Lloyd, R. Lamb, and E. Grotewold
Participation of the Arabidopsis bHLH Factor GL3 in Trichome Initiation Regulatory Events
Plant Physiology, November 1, 2007; 145(3): 736 - 746.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
Y. Gan, H. Yu, J. Peng, and P. Broun
Genetic and Molecular Regulation by DELLA Proteins of Trichome Development in Arabidopsis
Plant Physiology, November 1, 2007; 145(3): 1031 - 1042.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
R. Zentella, Z.-L. Zhang, M. Park, S. G. Thomas, A. Endo, K. Murase, C. M. Fleet, Y. Jikumaru, E. Nambara, Y. Kamiya, et al.
Global Analysis of DELLA Direct Targets in Early Gibberellin Signaling in Arabidopsis
PLANT CELL, October 1, 2007; 19(10): 3037 - 3057.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
I.-C. Jang, S. W. Yang, J.-Y. Yang, and N.-H. Chua
Independent and interdependent functions of LAF1 and HFR1 in phytochrome A signaling
Genes & Dev., August 15, 2007; 21(16): 2100 - 2111.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
T. Ishida, S. Hattori, R. Sano, K. Inoue, Y. Shirano, H. Hayashi, D. Shibata, S. Sato, T. Kato, S. Tabata, et al.
Arabidopsis TRANSPARENT TESTA GLABRA2 Is Directly Regulated by R2R3 MYB Transcription Factors and Is Involved in Regulation of GLABRA2 Transcription in Epidermal Differentiation
PLANT CELL, August 1, 2007; 19(8): 2531 - 2543.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
A. Macquet, M.-C. Ralet, J. Kronenberger, A. Marion-Poll, and H. M. North
In situ, Chemical and Macromolecular Study of the Composition of Arabidopsis thaliana Seed Coat Mucilage
Plant Cell Physiol., July 1, 2007; 48(7): 984 - 999.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
B. Dombrecht, G. P. Xue, S. J. Sprague, J. A. Kirkegaard, J. J. Ross, J. B. Reid, G. P. Fitt, N. Sewelam, P. M. Schenk, J. M. Manners, et al.
MYC2 Differentially Modulates Diverse Jasmonate-Dependent Functions in Arabidopsis
PLANT CELL, July 1, 2007; 19(7): 2225 - 2245.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
R. Tominaga, M. Iwata, K. Okada, and T. Wada
Functional Analysis of the Epidermal-Specific MYB Genes CAPRICE and WEREWOLF in Arabidopsis
PLANT CELL, July 1, 2007; 19(7): 2264 - 2277.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
K. Baumann, M. Perez-Rodriguez, D. Bradley, J. Venail, P. Bailey, H. Jin, R. Koes, K. Roberts, and C. Martin
Control of cell and petal morphogenesis by R2R3 MYB transcription factors
Development, May 1, 2007; 134(9): 1691 - 1701.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
H. Mano, F. Ogasawara, K. Sato, H. Higo, and Y. Minobe
Isolation of a Regulatory Gene of Anthocyanin Biosynthesis in Tuberous Roots of Purple-Fleshed Sweet Potato
Plant Physiology, March 1, 2007; 143(3): 1252 - 1268.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
F. Paolocci, M. P. Robbins, L. Madeo, S. Arcioni, S. Martens, and F. Damiani
Ectopic Expression of a Basic Helix-Loop-Helix Gene Transactivates Parallel Pathways of Proanthocyanidin Biosynthesis. Structure, Expression Analysis, and Genetic Control of Leucoanthocyanidin 4-Reductase and Anthocyanidin Reductase Genes in Lotus corniculatus
Plant Physiology, January 1, 2007; 143(1): 504 - 516.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
M. L. Churchman, M. L. Brown, N. Kato, V. Kirik, M. Hulskamp, D. Inze, L. De Veylder, J. D. Walker, Z. Zheng, D. G. Oppenheimer, et al.
SIAMESE, a Plant-Specific Cell Cycle Regulator, Controls Endoreplication Onset in Arabidopsis thaliana
PLANT CELL, November 1, 2006; 18(11): 3145 - 3157.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
A. M. Takos, F. W. Jaffe, S. R. Jacob, J. Bogs, S. P. Robinson, and A. R. Walker
Light-Induced Expression of a MYB Gene Regulates Anthocyanin Biosynthesis in Red Apples
Plant Physiology, November 1, 2006; 142(3): 1216 - 1232.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
A. Feller, J. M. Hernandez, and E. Grotewold
An ACT-like Domain Participates in the Dimerization of Several Plant Basic-helix-loop-helix Transcription Factors
J. Biol. Chem., September 29, 2006; 281(39): 28964 - 28974.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
J. Liu, K.-F. Xia, J.-C. Zhu, Y.-G. Deng, X.-L. Huang, B.-L. Hu, X. Xu, and Z.-F. Xu
The Nightshade Proteinase Inhibitor IIb Gene is Constitutively Expressed in Glandular Trichomes
Plant Cell Physiol., September 1, 2006; 47(9): 1274 - 1284.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
Y. Gan, R. Kumimoto, C. Liu, O. Ratcliffe, H. Yu, and P. Broun
GLABROUS INFLORESCENCE STEMS Modulates the Regulation by Gibberellins of Epidermal Differentiation and Shoot Maturation in Arabidopsis
PLANT CELL, June 1, 2006; 18(6): 1383 - 1395.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
F. Quattrocchio, W. Verweij, A. Kroon, C. Spelt, J. Mol, and R. Koes
PH4 of Petunia Is an R2R3 MYB Protein That Activates Vacuolar Acidification through Interactions with Basic-Helix-Loop-Helix Transcription Factors of the Anthocyanin Pathway
PLANT CELL, May 1, 2006; 18(5): 1274 - 1291.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
Y. Morita, M. Saitoh, A. Hoshino, E. Nitasaka, and S. Iida
Isolation of cDNAs for R2R3-MYB, bHLH and WDR Transcriptional Regulators and Identification of c and ca Mutations Conferring White Flowers in the Japanese Morning Glory
Plant Cell Physiol., April 1, 2006; 47(4): 457 - 470.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
K. Schwinn, J. Venail, Y. Shang, S. Mackay, V. Alm, E. Butelli, R. Oyama, P. Bailey, K. Davies, and C. Martin
A Small Family of MYB-Regulatory Genes Controls Floral Pigmentation Intensity and Patterning in the Genus Antirrhinum
PLANT CELL, April 1, 2006; 18(4): 831 - 851.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
M. T. Sweeney, M. J. Thomson, B. E. Pfeil, and S. McCouch
Caught Red-Handed: Rc Encodes a Basic Helix-Loop-Helix Protein Conditioning Red Pericarp in Rice
PLANT CELL, February 1, 2006; 18(2): 283 - 294.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
T. Kurata, T. Ishida, C. Kawabata-Awai, M. Noguchi, S. Hattori, R. Sano, R. Nagasaka, R. Tominaga, Y. Koshino-Kimura, T. Kato, et al.
Cell-to-cell movement of the CAPRICE protein in Arabidopsis root epidermal cell differentiation
Development, December 15, 2005; 132(24): 5387 - 5398.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S. Teng, J. Keurentjes, L. Bentsink, M. Koornneef, and S. Smeekens
Sucrose-Specific Induction of Anthocyanin Biosynthesis in Arabidopsis Requires the MYB75/PAP1 Gene
Plant Physiology, December 1, 2005; 139(4): 1840 - 1852.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
C.-R. Xu, C. Liu, Y.-L. Wang, L.-C. Li, W.-Q. Chen, Z.-H. Xu, and S.-N. Bai
Histone acetylation affects expression of cellular patterning genes in the Arabidopsis root epidermis
PNAS, October 4, 2005; 102(40): 14469 - 14474.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
K.-H. Jung, M.-J. Han, Y.-S. Lee, Y.-W. Kim, I. Hwang, M.-J. Kim, Y.-K. Kim, B. H. Nahm, and G. An
Rice Undeveloped Tapetum1 Is a Major Regulator of Early Tapetum Development
PLANT CELL, October 1, 2005; 17(10): 2705 - 2722.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
S. Vanderauwera, P. Zimmermann, S. Rombauts, S. Vandenabeele, C. Langebartels, W. Gruissem, D. Inze, and F. Van Breusegem
Genome-Wide Analysis of Hydrogen Peroxide-Regulated Gene Expression in Arabidopsis Reveals a High Light-Induced Transcriptional Cluster Involved in Anthocyanin Biosynthesis
Plant Physiology, October 1, 2005; 139(2): 806 - 821.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
L. Serna
Epidermal cell patterning and differentiation throughout the apical-basal axis of the seedling
J. Exp. Bot., August 1, 2005; 56(418): 1983 - 1989.
[Abstract] [Full Text] [PDF]

Home page
 Plant Cell PhysiolHome page
Y. Koshino-Kimura, T. Wada, T. Tachibana, R. Tsugeki, S. Ishiguro, and K. Okada
Regulation of CAPRICE Transcription by MYB Proteins for Root Epidermis Differentiation in Arabidopsis
Plant Cell Physiol., June 1, 2005; 46(6): 817 - 826.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
V. V. Symonds, A. V. Godoy, T. Alconada, J. F. Botto, T. E. Juenger, J. J. Casal, and A. M. Lloyd
Mapping Quantitative Trait Loci in Multiple Populations of Arabidopsis thaliana Identifies Natural Allelic Variation for Trichome Density
Genetics, March 1, 2005; 169(3): 1649 - 1658.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
C. Bernhardt, M. Zhao, A. Gonzalez, A. Lloyd, and J. Schiefelbein
The bHLH genes GL3 and EGL3 participate in an intercellular regulatory circuit that controls cell patterning in the Arabidopsis root epidermis
Development, January 15, 2005; 132(2): 291 - 298.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
J. M. Hernandez, G. F. Heine, N. G. Irani, A. Feller, M.-G. Kim, T. Matulnik, V. L. Chandler, and E. Grotewold
Different Mechanisms Participate in the R-dependent Activity of the R2R3 MYB Transcription Factor C1
J. Biol. Chem., November 12, 2004; 279(46): 48205 - 48213.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
L. Serna
A Network of Interacting Factors Triggering Different Cell Fates
PLANT CELL, September 1, 2004; 16(9): 2258 - 2263.
[Full Text] [PDF]

Home page
 Plant Physiol.Home page
L. Hennig, W. Gruissem, U. Grossniklaus, and C. Kohler
Transcriptional Programs of Early Reproductive Stages in Arabidopsis
Plant Physiology, July 1, 2004; 135(3): 1765 - 1775.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
T. L. Western, D. S. Young, G. H. Dean, W. L. Tan, A. L. Samuels, and G. W. Haughn
MUCILAGE-MODIFIED4 Encodes a Putative Pectin Biosynthetic Enzyme Developmentally Regulated by APETALA2, TRANSPARENT TESTA GLABRA1, and GLABRA2 in the Arabidopsis Seed Coat
Plant Physiology, January 1, 2004; 134(1): 296 - 306.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
C. Bernhardt, M. M. Lee, A. Gonzalez, F. Zhang, A. Lloyd, and J. Schiefelbein
The bHLH genes GLABRA3 (GL3) andENHANCER OF GLABRA3 (EGL3) specify epidermal cell fate in the Arabidopsis root
Development, December 29, 2003; 130(26): 6431 - 6439.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
J. J. Esch, M. Chen, M. Sanders, M. Hillestad, S. Ndkium, B. Idelkope, J. Neizer, and M. D. Marks
A contradictory GLABRA3 allele helps define gene interactions controlling trichome development in Arabidopsis
Development, December 15, 2003; 130(24): 5885 - 5894.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
K.-Y. Yang, Y.-M. Kim, S. Lee, P.-S. Song, and M.-S. Soh
Overexpression of a Mutant Basic Helix-Loop-Helix Protein HFR1, HFR1-{Delta}N105, Activates a Branch Pathway of Light Signaling in Arabidopsis
Plant Physiology, December 1, 2003; 133(4): 1630 - 1642.
[Abstract] [Full Text]

Home page
 Plant CellHome page
P. C. Bailey, C. Martin, G. Toledo-Ortiz, P. H. Quail, E. Huq, M. A. Heim, M. Jakoby, M. Werber, and B. Weisshaar
Update on the Basic Helix-Loop-Helix Transcription Factor Gene Family in Arabidopsis thaliana
PLANT CELL, November 1, 2003; 15(11): 2497 - 2502.
[Full Text] [PDF]


© The Company of Biologists Ltd 2003