Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants

Lints, T. J., Parsons, L. M., Hartley, L., Lyons, I. and Harvey, R. P. (1993). Development 119, 419-431.

We have detected four errors in the sequence for NkX-2.5a cDNA given in Fig. 1. The corrected version is printed below.

Fig. 1.

DNA sequence of the Nkx-2.5a cDNA clone with the predicted Nkx-2.5 amino acid sequence. The start and stop codons, and the homeobox are boxed. The amino terminal homology is underlined (see Fig. 2B). The NK2-specific domain is doubly underlined (see Fig. 2C). The region between the homeodomain and the NK2-specific domain shared by Nkx2.5 and Nkx-2.6 is indicated with dashes (Fig. 2C). A possible polyadenylation signal and mRNA instability sequence are respectively overlined and underlined in bold.

Fig. 1.

DNA sequence of the Nkx-2.5a cDNA clone with the predicted Nkx-2.5 amino acid sequence. The start and stop codons, and the homeobox are boxed. The amino terminal homology is underlined (see Fig. 2B). The NK2-specific domain is doubly underlined (see Fig. 2C). The region between the homeodomain and the NK2-specific domain shared by Nkx2.5 and Nkx-2.6 is indicated with dashes (Fig. 2C). A possible polyadenylation signal and mRNA instability sequence are respectively overlined and underlined in bold.

We would also like to point out that the Drosophila NK4/msh-2 gene has been renamed tinman (see Bodmer (1993) Development 118, 719-729).