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Development at a glance – Vascular endothelial growth factor signaling in development and disease
In a new poster and article, Sinem Karaman, Veli-Matti Leppänen and Kari Alitalo provide an overview of the VEGF signalling pathway and highlight the functions of VEGF/VEGFR signalling in blood and lymphatic vessel development and pathology.
Review – Polyploidy in tissue homeostasis and regeneration
In regenerating tissues, polyploidization is a commonly used strategy to compensate for cell loss. Jan Inge Øvrebø and Bruce A. Edgar review how such tissues are less dependent on resident stem cells, an advantage that may be exploited in regenerative therapy.
The people behind the papers – Takanori Wakatake & Ken Shirasu
Parasitic plants rely on the haustorium, a specialised root structure that invades host root vasculature to derive nutrients and water. A recent Research Article addresses the developmental origins of these crucial structures in the facultative root parasite Phtheirospermum japonicum. The Node caught up with first author Takanori Wakatake and his supervisor Ken Shirasu to find out more about the story.
The Node – Building the BSDB family network.
The Node has digitised a network originally made at the BSDB Spring Meeting in Warwick that shows the connections between attendees and their advisers. You can add yourself if you’re not on there yet, and explore the digitised network.
Meet the team!
The Development team are going to be out and about through July and August. Come and meet Reviews Editor Seema Grewal at the SDB Annual Meeting; Executive Editor Katherine Brown at the GRC Neural Development Conference and the Node Community Manager Aidan Maartens at the SCDB Annual Meeting.
Call for papers – Development at the single cell level
Development is pleased to welcome submissions for an upcoming special issue on ‘Development at the single cell level’, guest-edited by Allon Klein and Barbara Treutlein. This special issue aims to showcase the best research in stem cell and developmental biology, building on the rapidly evolving tools of single cell analysis. Submission deadline: 31 October 2018.
preLights – To regenerate, or not to regenerate?
Shikha Nayar highlights a preprint from Catherina G. Becker and co-workers that sheds light on key immune mechanisms and spatiotemporal dynamics that orchestrate spinal cord regeneration in zebrafish. This preLight includes a response from the author team on the surprising complexity of regeneration in their study.
We are pleased to announce that Development will now feature recent preLights that are of interest to the developmental biology community as part of each issue's Table of Contents.
Articles of interest in our sister journals
Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis
Francesca Pala, Daniela Di Girolamo, Sébastien Mella, Siham Yennek, Laurent Chatre, Miria Ricchetti, Shahragim Tajbakhsh. J Cell Sci 2018 131: jcs21297
High-throughput live-imaging of embryos in microwell arrays using a modular specimen mounting system
Seth Donoughe, Chiyoung Kim, Cassandra G. Extavour. Biology Open 2018 7: bio031260