Masanori Kawaguchi, Kota Sugiyama and Yoshiyuki Seki at Kwansei Gakuin University in Japan tell us the story behind their research addressing the evolution of pluripotency with an analysis of the function of PRDM14 in zebrafish, amphioxus and sea urchin.
Read this Primer by Salvador Herrera and Erika Bach to get an overview of the role of JAK/STAT signaling in stem cells and regeneration in Drosophila testis, intestine and appendages and see the similarities between Drosophila and vertebrates.
Developmental biology has achieved many amazing accomplishments over the years, but the field needs to consider new strategies for increasing its visibility within the wider scientific community, writes Leonard Zon.
Majlinda Lako and colleagues share an integrated transcriptional and immunohistochemical analysis of human retinogenesis in vivo. Read the highlight and the full Human Development article
Development is pleased to welcome submissions for an upcoming Special Issue on ‘Chromatin and Epigenetics’, edited by Benoit Bruneau, Haruhiko Koseki, Susan Strome and Maria-Elena Torres-Padilla. This special issue aims to showcase the best research covering the chromatin-based and epigenetic mechanisms which regulate development across the plant and animal kingdoms. Submission deadline: 31 March 2019.
Extensive and dynamic genome binding by a steroid hormone receptor highlights the interconnection between systemic and local cues for organ development, shows a preprint written by Christopher Uyehara and Daniel McKay and highlighted by Natalie Dye.
The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch
Kelsey F. Sugrue, Anjali A. Sarkar, Linda Leatherbury, Irene E. Zohn
Disease Models & Mechanisms 2019 12: dmm036491
Maintenance of cell fates and regulation of the histone variant H3.3 by TLK kinase in Caenorhabditis elegans
Yukimasa Shibata, Yoshiyuki Seki, Kiyoji Nishiwaki
Biology Open 2019 8: bio038448