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About the Cover

April 15, 2013; 140 (8)

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Cover: Confocal image (extended focus z-stack) of an E10.5 mouse embryo (lateral view, thorax) immunostained for PECAM (endothelial factor present in the vasculature; red) and β-III-tubulin (neurons; green) and with DAPI (nuclei; blue). This image, taken by Joyce Pieretti, Manuela Truebano, Saori Tani and Daniela Di Bella at the 2012 Woods Hole MBL Embryology Course, was chosen by readers of the Node (http://thenode.biologists.com).

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Development: 140 (8)
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    Trans-splicing of the C. elegans let-7 primary transcript developmentally regulates let-7 microRNA biogenesis and let-7 family microRNA activity

    Charles Nelson, Victor Ambros
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    Lmx1a drives Cux2 expression in the cortical hem through activation of a conserved intronic enhancer

    Santiago Fregoso, Brett E. Dwyer, Santos J. Franco
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    Rho-of-plant-activated root hair formation requires Arabidopsis YIP4a/b gene function

    Delphine Gendre, Anirban Baral, Xie Dang, Nicolas Esnay, Yohann Boutté, Thomas Stanislas, Thomas Vain, Stéphane Claverol, Anna Gustavsson, Deshu Lin, Markus Grebe, Rishikesh P. Bhalerao
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    Generating intravital super-resolution movies with conventional microscopy reveals actin dynamics that construct pioneer axons

    Yide Zhang, Evan L. Nichols, Abigail M. Zellmer, Ian H. Guldner, Cody Kankel, Siyuan Zhang, Scott S. Howard, Cody J. Smith
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    ATML1 activity is restricted to the outermost cells of the embryo through post-transcriptional repressions

    Hiroyuki Iida, Ayaka Yoshida, Shinobu Takada
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The people behind the papers – Masanori Kawaguchi, Kota Sugiyama and Yoshiyuki Seki

Yoshiyuki Seki, Kota Sugiyama and Masanori Kawaguchi

Masanori Kawaguchi, Kota Sugiyama and Yoshiyuki Seki at Kwansei Gakuin University in Japan tell us the story behind their research addressing the evolution of pluripotency with an analysis of the function of PRDM14 in zebrafish, amphioxus and sea urchin.


Primer - JAK/STAT signaling in stem cells and regeneration: from Drosophila to vertebrates

Part of Fig. 3: JAK/STAT signaling in homeostasis and regeneration in the Drosophila intestine

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Spotlight - Improving the visibility of developmental biology: time for induction and specification

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Research Highlight - A deeper look at human retina development

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Call for papers: Chromatin and Epigenetics

Call for papers: Chromatin and Epigenetics

Development is pleased to welcome submissions for an upcoming Special Issue on ‘Chromatin and Epigenetics’, edited by Benoit Bruneau, Haruhiko Koseki, Susan Strome and Maria-Elena Torres-Padilla. This special issue aims to showcase the best research covering the chromatin-based and epigenetic mechanisms which regulate development across the plant and animal kingdoms. Submission deadline: 31 March 2019. 


PreLights – A direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila

PreLighter Natalie Dye

Extensive and dynamic genome binding by a steroid hormone receptor highlights the interconnection between systemic and local cues for organ development, shows a preprint written by Christopher Uyehara and Daniel McKay and highlighted by Natalie Dye.


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Kelsey F. Sugrue, Anjali A. Sarkar, Linda Leatherbury, Irene E. Zohn
Disease Models & Mechanisms 2019 12: dmm036491

Maintenance of cell fates and regulation of the histone variant H3.3 by TLK kinase in Caenorhabditis elegans
Yukimasa Shibata, Yoshiyuki Seki, Kiyoji Nishiwaki
Biology Open 2019 8: bio038448

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