It is becoming increasingly clear that cellular metabolite levels regulate the activity of signaling pathways, and conversely that signaling pathways affect cellular physiology and growth via metabolic pathways. Thus, metabolism and signaling mutually influence each other. The Company of Biologists' Workshop ‘Metabolism in Development and Disease’ brought together people studying signaling and development with people studying metabolism, particularly in a cancer context. This Meeting Review discusses examples of talks that illustrated this principle.
The authors declare no competing or financial interests.
This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.