The single most important criterion for acceptance in Development is scientific excellence. Articles must therefore pose and test a significant hypothesis and should provide novel perspectives and approaches to understanding development. Experimental papers are given the highest priority, although the submission of manuscripts that are entirely theoretical or descriptive, or that combine these approaches with experimental analysis, is encouraged, providing they report the necessary novel insights into developmental mechanisms.
Criteria for Stem Cells & Regeneration papers
Development has a dedicated section of the journal for stem cells and regeneration papers. The journal welcomes and encourages the submission of papers in these fields that offer new insights into the cells, pathways or molecules involved in self-renewal, cell fate specification, differentiation, regeneration and reprogramming. Stem cell biology papers need not be limited to developing organisms. Development will also consider reports of technical advances in stem cell identification and manipulation. Reports of in vitro differentiation protocols are welcome but these studies should be based on or should provide insight into the mechanisms underlying cell differentiation, and the reported protocols should demonstrate efficiency, robustness and reproducibility across several independent stem cell lines or cultures.
Criteria for Techniques and Resources papers
Techniques and Resources papers should describe a novel technique or substantial advance of an existing technique, or a new resource that will have a significant impact on developmental biology research. Techniques and Resources papers can be in short (Research Report) or long (Research Article) format. Of particular interest are technical papers describing: new methods for the live imaging of cellular processes, single cells or whole organs during different stages of development in an experimental organism; new genetic techniques for the analysis of in vivo gene function; and new approaches for studying stem cells during development, in adult organs and during regeneration. The new technique should be described in sufficient detail to be easily replicated in other laboratories, and validation of the approach should be included. Technical papers submitted in the Research Article format should include an application of the technique to an area of developmental or stem cell biology. We also welcome submission of Resource papers describing new databases, systems-level datasets or genetic resources that will be of major value to the developmental biology community. The data or resource described must be made available to the community with minimal restrictions upon publication.
Criteria for papers reporting results of screens
Where a study involves a genome-wide or high-throughput screen, authors need to provide additional and novel insight into the functions of the identified targets by either verifying at least one target such that it is shown to be a crucial functional component of the network or phenotype of interest, or by using the data to make system-wide predictions about how the transcriptional network acts. Experiments should ideally be performed to test these predictions where it is feasible to do so.