The editorial team occasionally selects specific papers that they feel are appropriate for press releases. Below is a list of recent press releases distributed by the journal.
Peripheral nerve injuries, such as those resulting from neuropathies, physical trauma or surgery, are common and can cause partial or complete loss of nerve function and a reduced quality of life. Now, researchers are able to produce large quantities of specialised cells known as Schwann cells that could be used to help treat such injuries. This strategy offers great potential in cell-based therapies for peripheral nerve injuries, including spinal cord injuries. Read the full release Read the paper
Millions of people worldwide have permanent hearing and balance impairments due to damage to the hair cells in their inner ears. Now, researchers have developed a simple strategy to produce hair cells more efficiently than previously reported. A similar strategy could be used in the future to produce large numbers of hair cells for use in drug screening or cell replacement therapies. Read the full release Read the paper
Obesity has been linked to fertility problems and long-lasting effects on offspring, partially because overnutrition in females causes damage to the egg cells they produce. Now, researchers are able to reverse this damage in the eggs of obese mice, leading to improved fertility and embryo development. This work suggests that some of the effects of obesity on fertility may be reverted by therapeutic intervention. Read the full release Read the paper
The repair of large bone defects and damaged cartilage remains a significant clinical challenge, with current strategies unable to reliably generate the cells that make bone and cartilage. Now, researchers are able to produce such cells by exposing embryonic stem cells to a combination of small molecules, mimicking normal development. This strategy is easily scalable, offering great potential in bone and cartilage regenerative medicine. Read the full release Read the paper
Cardiovascular disease (CVD) is responsible for approximately one-third of all deaths. A major problem with CVD is that adult hearts do not repair well after injury. Now, researchers have discovered a way to change that. By identifying and manipulating the normal signals that block heart repair, they were able to show complete functional heart recovery in adult mice after myocardial infarction, which mimics a human heart attack. This breakthrough brings new hope for treating CVD. Read the full release Read the paper