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About the Cover
Cover: A gathering of sea urchin plutei viewed under crossed polarized light reveals the birefringent calcite spicules that form the internal skeleton of the larvae. In the sea urchin embryo, the patterning of spicules depends in part upon the allocation of ectoderm during early development. Notch signaling plays an important role in regulating the amount of ectoderm by mediating the position of the ectoderm-endoderm boundary. For further details, see article by D. R. Sherwood and D. R. McClay, in this issue, Development 128, 2221-2232.
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