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Cover: Understanding the developmental signals that enable cells to build complex tissue and organ structures may lead to major advances in regenerative medicine. Here, two ectopic limbs have been induced in Xenopus laevis by modulating expression of K+ channels and thereby altering bioelectrical signaling in the early embryo (image courtesy of Sherry Aw). See meeting review by Ingber and Levin on p. 2541.

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