iPSC
- Single-cell mechanical phenotype is an intrinsic marker of reprogramming and differentiation along the mouse neural lineage
Summary: Stiffening accompanies reprogramming of murine fetal neural progenitor cells towards pluripotency and is reversed in neural differentiation of pluripotent cells.
- Using brain organoids to understand Zika virus-induced microcephaly
Summary: This Spotlight article summarises the latest advances in using cerebral organoids to model Zika virus infection and the resulting pathology.
- A developmental framework for induced pluripotency
Summary: This Review explores the differences and similarities between the biological processes driving developmental cell differentiation and those mediating cell reprogramming.
- Interspecific in vitro assay for the chimera-forming ability of human pluripotent stem cells
Summary: An approach to assess the chimera-forming ability of PSCs is developed and used to assess the developmental potential of rodent, monkey and human PSCs.