- Stomach curvature is generated by left-right asymmetric gut morphogenesis
- Distinct and redundant functions of Esama and VE-cadherin during vascular morphogenesis
Summary: Genetic analyses of Esama function in mutant zebrafish embryos reveal specific and redundant functions of Esama and VE-cadherin proteins in endothelial cell recognition and blood vessel morphogenesis.
- Automated cell tracking identifies mechanically oriented cell divisions during Drosophila axis elongation
Summary: Using body axis elongation in Drosophila embryos as a model, novel image analysis and machine learning methods identify cell divisions oriented by mechanical cues to reduce strain.
- Using synthetic biology to explore principles of development
Summary: This Review highlights how synthetic biology-based approaches have been used to explore the principles underlying patterning, differentiation and morphogenesis during development.
- Self-organisation after embryonic kidney dissociation is driven via selective adhesion of ureteric epithelial cells
Summary: Time-lapse imaging, high-resolution confocal analyses and mathematical modelling demonstrate how component cells of a developing tissue can reform complex multicellular structures, even after dissociation.
- Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish
Summary: This Development at a Glance article summarises how knowledge gained from developmental biology can be used to guide human in vitro organogenesis, and discusses the potential applications of this technology.
- Integrin suppresses neurogenesis and regulates brain tissue assembly in planarian regeneration
- Neural tube closure: cellular, molecular and biomechanical mechanisms
Summary: This Review discusses the cellular, molecular and biomechanical mechanisms involved in neural tube closure, focusing on the most recent advances in the field.
- Nodal and FGF coordinate ascidian neural tube morphogenesis
Summary: Live imaging of neural tube morphogenesis in Ciona uncovers roles for FGF and Nodal signaling in controlling the intercalation and stacking behaviors of cells.
- Monitoring cell-cell contacts in vivo in transgenic animals
Summary: A synthetic genetic system is used to monitor cell-cell contacts in animals, to genetically manipulate interacting cells, and to investigate the connectivity of neurons in brain circuits.