- Enthesis regeneration: a role for Gli1+ progenitor cells
Summary: Tendon enthesis progenitor cells are capable of healing enthesis injuries in immature mice, in a hedgehog pathway-dependent manner. This capacity is lost in mature animals.
- Direct conversion of root primordium into shoot meristem relies on timing of stem cell niche development
- Shh promotes direct interactions between epidermal cells and osteoblast progenitors to shape regenerated zebrafish bone
- Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells
Summary: Paracrine signals from MSCs or HUVECs are able to promote hepatocyte differentiation independently, but both must co-exist to allow for the cell-cell contact and organization into a 3D liver organoid.
- Development of a human cardiac organoid injury model reveals innate regenerative potential
Summary: Human cardiac organoids, which represent immature tissue, show an innate regenerative response and robust recovery after cryoinjury without pathological fibrosis or hypertrophy.
- Integrins are required for tissue organization and restriction of neurogenesis in regenerating planarians
- Retinoic acid receptor regulation of epimorphic and homeostatic regeneration in the axolotl
Summary: A unique transcriptional program that regulates the coordination of positional information and tissue differentiation in regenerating salamander limbs and tails .
- Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration
Summary: In mouse, mutations in different subunits of the PRC2 complex have specific effects on urothelial progenitor cell proliferation and differentiation.
- Early bioelectric activities mediate redox-modulated regeneration