Special Issue: development at the single cell level

Our Special Issue on single cell approaches to developmental biology contains a wealth of content, from research papers using various model systems to the latest cutting edge techniques and a selection of reviews and commentaries surveying the field and its future.

Meet New York-based Eduardo Leyva-Díaz and Oliver Hobert, authors of a recent Development paper on transcriptional autoregulation in C. elegans. 

The Development team are going to be out and about through June and July. Do come and meet them! Going to the Gordon conference on Developmental Biology in South Hadley, USA, June 16 – 21? Meet our Executive Editor Katherine Brown. At the ISSCR 2019: The global stem cell event in Los Angeles, 26-29 June you can meet Senior Editor Seema Grewal. Reviews Editor Alex Eve and Online Editor Aidan Maartens will be at the SDB 78th Annual Meeting in Boston, USA, July 26-30.

The Company of Biologists Workshops - Chromatin-Based Regulation of Development

Watch a short video from this workshop, where we discussed what mechanisms related to chromatin biology inform developmental processes, explored plans to integrate unsolved developmental questions with exciting new avenues in chromatin biology, and which outstanding questions in gene regulation might be best revealed in the context of dynamic cell fate transitions. Find out about upcoming workshops here.

Are TAD borders that important to prevent enhancer rewiring? preLighter Jesus Victorino highlights a preprint by Wendy Bickmore and Laura Lettice’s team which shows that tissue-specific enhancers maintain robust control of Shh gene expression after challenging the architectural chromatin context.

Catch up with other recent preLights selected for the developmental biology community.

Articles of interest in our sister journals

Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure
Max B. Butler, Nina E. Short, Eirini Maniou, Paula Alexandre, Nicholas D. E. Greene, Andrew J. Copp, Gabriel L. Galea
Journal of Cell Science

Suppressor of Fused regulates the proliferation of postnatal neural stem and precursor cells via a Gli3-dependent mechanism
Hector G. Gomez, Hirofumi Noguchi, Jesse Garcia Castillo, David Aguilar, Samuel J. Pleasure, Odessa R. Yabut
Biology Open