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JOURNAL ARTICLES
CLAVATA1, a regulator of meristem and flower development in Arabidopsis
S.E. Clark, M.P. Running, E.M. Meyerowitz
Development 1993 119: 397-418;

Summary

We have investigated the effects on plant development of mutations in the Arabidopsis thaliana CLAVATA1 gene. In clavata1 plants, vegetative, inflorescence and floral meristems are all enlarged relative to wild type. The apical meristem can fasciate in the more severe mutant alleles, and this fasciation can occur prior to the transition to flowering. Flowers of clavata1 plants can have increased numbers of organs in all four whorls, and can also have additional whorls not present in wild-type flowers. Double mutant combinations of clavata1 with agamous, apetala2, apetala3 and pistillata indicate that CLAVATA1 controls the underlying floral meristem structure upon which these homeotic genes act. Double mutant combinations of clavata1 with apetala1 and leafy indicate CLAVATA1 plays a role in establishing and maintaining floral meristem identity, in addition to its role in controlling meristem size. In support of this, RNA expression patterns of AGAMOUS and APETALA1 are altered in clavata1 flowers.

REFERENCES

    1. Bowman J. L.,
    2. Smyth D. R.,
    3. Meyerowitz E. M.
    (1989). Genes directing flower development in Arabidopsis. Plant Cell 1, 37–52
    OpenUrlAbstract/FREE Full Text
    1. Bowman J. L.,
    2. Smyth D. R.,
    3. Meyerowitz E. M.
    (1991). Genetic interactions among floral homeotic genes of Arabidopsis. Development 112, 1–20
    OpenUrlAbstract
    1. Coen E. S.,
    2. Meyerowitz E. M.
    (1991). The war of the whorls: genetic interactions controlling flower development. Nature 353, 31–37
    OpenUrlCrossRefPubMed
    1. Drews G. N.,
    2. Bowman J. L.,
    3. Meyerowitz E. M.
    (1991). Negative regulation of the Arabidopsis homeotic gene AGAMOUS by the APETALA2 product. Cell 65, 991–1002
    OpenUrlCrossRefPubMedWeb of Science
    1. Goto N.,
    2. Kumagai T.,
    3. Koornneef M.
    (1991). Flowering responses to light-breaks in photomorphogenic mutants of Arabidopsis thaliana, a long day plant. Physiol. Plant 83, 209–215
    OpenUrlCrossRef
    1. Huala E.,
    2. Sussex I. M.
    (1992). LEAFY interacts with floral homeotic genes to regulate Arabidopsis floral development. Plant Cell 4, 901–913
    OpenUrlAbstract/FREE Full Text
    1. Irish V. F.,
    2. Sussex I. M.
    (1990). Function of the apetala-1 gene during Arabidopsis floral development. Plant Cell 2, 741–751
    OpenUrlAbstract/FREE Full Text
    1. Jack T.,
    2. Brockman L. L.,
    3. Meyerowitz E. M.
    (1992). The homeotic gene APETALA3 of Arabidopsisthaliana encodes a MADS box and is expressed in petals and stamens. Cell 68, 683–697
    OpenUrlCrossRefPubMedWeb of Science
    1. Koornneef M.,
    2. van Eden J.,
    3. Hanhart C. J.,
    4. Stam P.,
    5. Braaaksma F. J.,
    6. Feenstra W. J.
    (1983). Linkage map of Arabidopsisthaliana. J. Hered 74, 265–272
    OpenUrlAbstract/FREE Full Text
    1. Leyser H. M. O.,
    2. Furner I. J.
    (1992). Characterization of three shoot apical meristem mutants of Arabidopsis thaliana. Development 116, 397–403
    OpenUrlAbstract/FREE Full Text
    1. Mandel M. A.,
    2. Gustafson-Brown C.,
    3. Savidge B.,
    4. Yanofsky M. F.
    (1992). Molecular characterization of the Arabidopsis floral homeotic gene APETALA1. Nature 360, 273–277
    OpenUrlCrossRefPubMed
    1. Medford J. I.,
    2. Behringer F. J.,
    3. Callos J. D.,
    4. Feldmann K. A.
    (1992). Normal and abnormal development in the Arabidopsis vegetative shoot apex. Plant Cell 4, 631–643
    OpenUrlAbstract/FREE Full Text
    1. Mertens T. R.,
    2. Burdick A. B.
    (1954). The morphology, anatomy and genetics of a stem fasciation in Lycopersicon esculentum. Amer. J. Bot 41, 726–732
    OpenUrlCrossRef
    1. Meyerowitz E. M.,
    2. Bowman J. L.,
    3. Brockman L. L.,
    4. Drews G. N.,
    5. Jack T.,
    6. Sieburth L. E.,
    7. Weigel D.
    (1991). A genetic and molecular model for flower development in Arabidopsis thaliana. Development 1, 157–167
    OpenUrl
    1. Miksche J. P.,
    2. Brown J. A. M.
    (1965). Development of vegetative and floral meristems of Arabidopsis thaliana. Am. J. Bot 52, 533–537
    OpenUrlCrossRefWeb of Science
    1. Reed J. W.,
    2. Nagpal P.,
    3. Poole D. S.,
    4. Furuya M.,
    5. Chory J.
    (1993). Mutations in the gene for the red/far-red light receptor phytochrome B alter cell elongation and physiological responses throughout Arabidopsis development. Plant Cell 5, 147–157
    OpenUrlAbstract/FREE Full Text
    1. Satina S.,
    2. Blakeslee A. F.,
    3. Avery A. G.
    (1940). Demonstration of the three germ layers in the shoot apex of Datura by means of induced polyploidy in periclinal chimeras. Am. J. Bot 27, 895–905
    OpenUrlCrossRefWeb of Science
    1. Schultz E. A.,
    2. Haughn G. W.
    (1991). LEAFY, a homeotic gene that regulates inflorescence development in Arabidopsis. Plant Cell 3, 771–781
    OpenUrlAbstract/FREE Full Text
    1. Smyth D. R.,
    2. Bowman J. L.,
    3. Meyerowitz E. M.
    (1990). Early flower development in Arabidopsis. Plant Cell 2, 755–767
    OpenUrlAbstract/FREE Full Text
    1. Szymkowiak E. J.,
    2. Sussex I. M.
    (1992). The internal meristem layer (L3) determines floral meristem size and carpel number in tomato periclinal chimeras. Plant Cell 4, 1089–1100
    OpenUrlAbstract/FREE Full Text
    1. Vaughn J. G.
    (1952). Structure of the angiosperm apex. Nature 169, 458–459
    OpenUrl
    1. Vaughn J. G.,
    2. Jones F. R.
    (1953). Structure of the angiosperm inflorescence apex. Nature 171, 751–752
    OpenUrlPubMed
    1. Weigel D.,
    2. Alvarez J.,
    3. Smyth D. R.,
    4. Yanofsky M. F.,
    5. Meyerowitz E. M.
    (1992). LEAFY controls floral meristem identity in Arabidopsis. Cell 69, 843–859
    OpenUrlCrossRefPubMedWeb of Science
    1. Yanofsky M. F.,
    2. Ma H.,
    3. Bowman J. B.,
    4. Drews G. N.,
    5. Feldmann K. A.,
    6. Meyerowitz E. M.
    (1990). The protein encoded by the Arabidopsis homeotic gene AGAMOUS resembles transcription factors. Nature 346, 35–39
    OpenUrlCrossRefPubMed
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JOURNAL ARTICLES
CLAVATA1, a regulator of meristem and flower development in Arabidopsis
S.E. Clark, M.P. Running, E.M. Meyerowitz
Development 1993 119: 397-418;
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