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JOURNAL ARTICLES
Genetic control of sex determination in the germ line and soma of the housefly, Musca domestica
D. Hilfiker-Kleiner, A. Dubendorfer, A. Hilfiker, R. Nothiger
Development 1994 120: 2531-2538;

Summary

In Musca domestica, sex in the soma is cell autonomously determined by the male-determiner M, or by the female-determiner FD. Transplanted pole cells (precursors of the germ line) show that sex determination of germ cells is non-autonomous genotypically male pole cells form functional eggs in female hosts, and genotypically female pole cells form functional sperm in male hosts. When M/+ cells undergo oogenesis, a male-determining maternal effect predetermines offspring without M, i.e. of female genotype, to develop as fertile males. FD is epistatic to M in the female germ line, as it is in the soma, overruling the masculinizing effect of M. The results suggest that maternal F product is needed for activation of the zygotic F gene.

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JOURNAL ARTICLES
Genetic control of sex determination in the germ line and soma of the housefly, Musca domestica
D. Hilfiker-Kleiner, A. Dubendorfer, A. Hilfiker, R. Nothiger
Development 1994 120: 2531-2538;
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